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*  Sodium thiopental - Wikipedia
Inhaled anesthetics are eliminated relatively quickly, so that stopping the inhaled anesthetic will allow rapid return of ... Ketamine. *Neuroactive steroids (e.g., alfaxolone, pregnenolone (eltanolone), pregnenolone acetate, minaxolone, ORG-20599) ... Sodium thiopental would have to be given in large amounts to maintain an anesthetic plane, and because of its 11.5- to 26-hour ... Thiopental is famously associated with a number of anesthetic deaths in victims of the attack on Pearl Harbor. These deaths, ...
  https://en.wikipedia.org/wiki/Pentothal
*  Penn Medicine: New receptors could underlie the many actions of the anesthetic ketamine | EurekAlert! Science News
Their most recent study looked at ketamine, an anesthetic discovered in the 1960s and recently prescribed as an anti-depressant ... Researchers have identified an entirely new class of receptors that ketamine binds in the body, which may underlie its diverse ... Penn Medicine researchers are continuing their work in trying to understand the mechanisms through which anesthetics work to ... Penn Medicine: New receptors could underlie the many actions of the anesthetic ketamine First of its kind study uses olfactory ...
  https://www.eurekalert.org/pub_releases/2015-04/uops-pmn040115.php
*  Anesthetic Ketamine Impairs Rats' Recall of Previous Information:The Nitric Oxide Synthase Inhibitor N-nitro-l-arginine...
... ketamine, 100 mg/kg; ketamine, 100 mg/kg + L-NAME, 1 mg/kg; ketamine, 100 mg/kg + L-NAME, 3 mg/kg; ketamine, 100 mg/kg + L-NAME ... 2 Ketamine is widely used as an anesthetic in both clinical practice and animal research.3 Ketamine is devoid of cardiovascular ... Animals that received anesthetic ketamine explored significantly less during T2 with respect to the vehicle-treated rats (P , ... Posttraining administration of anesthetic ketamine did not disrupt the performance of mice in the passive avoidance test7 and ...
  http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1933530
*  Effect of S-ketamine as an Anesthetic Adjuvant to Propofol o... : The Journal of ECT
Home , June 2014 - Volume 30 - Issue 2 , Effect of S-ketamine as an Anesthetic Adjuvant to Propofol o... ... Effect of S-ketamine as an Anesthetic Adjuvant to Propofol on Treatment Response to Electroconvulsive Therapy in Treatment- ... Effect of S-ketamine as an anesthetic adjuvant to propofol on treatment response to electroconvulsive therapy in treatment- ... Effect of S-ketamine as an Anesthetic Adjuvant to Propofol on Treatment Response to Electroconvulsive Therapy in Treatment- ...
  http://journals.lww.com/ectjournal/Fulltext/2014/06000/Effect_of_S_ketamine_as_an_Anesthetic_Adjuvant_to.18.aspx?WT.mc_id=HPxADx20100319xMP
*  Sub-anesthetic doses of ketamine attenuate nicotine self-administration in rats, Neuroscience Letters | 10.1016/j.neulet.2018...
"Sub-anesthetic doses of ketamine attenuate nicotine self-administration in rats, Neuroscience Letters" on DeepDyve, the largest ... Sub-anesthetic doses of ketamine attenuate nicotine self-administration in rats. Sub-anesthetic doses of ketamine attenuate ... Sub-anesthetic doses of ketamine attenuate nicotine self-administration in rats. Rezvani, Amir H.; Tizabi, Yousef; Slade, Susan ... Sub-anesthetic concentrations of (R, S)-ketamine metabolites inhibit acetylcholine-evoked currents in α7 nicotinic ...
  https://www.deepdyve.com/lp/elsevier/sub-anesthetic-doses-of-ketamine-attenuate-nicotine-self-Gt9n5EXjcP
*  An Investigation to Dissociate the Analgesic and Anesthetic Properties of Ketamine Using Functional Magnetic Resonance Imaging ...
KETAMINE, a dissociative anesthetic, is as a noncompetitive antagonist to the phencyclidine site of the N -methyl-d-aspartate ( ... Ketamine is an anesthetic drug, and so it would be expected to have global cognitive effects. Behavioral pain scores are ... Ketamine produces analgesia at plasma concentrations of 100-200 ng/ml. 15-17 Standard intravenous anesthetic induction doses (2 ... Saline versus 200 ng/ml ketamine yielded a P value of 0.5, and saline versus 50 ng/ml ketamine yielded a P value of 0.7 (two- ...
  http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1942838
*  Ketamine's Split Personality: Risky Club Drug, Effective Anesthetic | KUOW News and Information
Ketamine's Split Personality: Risky Club Drug, Effective Anesthetic By Michaeleen Doucleff • Sep 7, 2016 ... "Ketamine is a safe, simple and cheap anesthetic," says Dr. Jannicke Mellin-Olsen, an anesthesiologist at Baerum Hospital in ... But over time, better anesthetics and analgesics slowly replaced ketamine in Western operating rooms, except for pediatric and ... "Ketamine is the most popular of all recreational drugs taken in South China, which is arguably the epicenter of global ketamine ...
  http://kuow.org/post/ketamines-split-personality-risky-club-drug-effective-anesthetic
*  How do we dream and what are nightmares?
Ketamine: Volunteers who took a sub-anesthetic dose of ketamine experienced more dream unpleasantness over 3 nights than those ... The incidence of unpleasant dreams after sub-anesthetic ketamine [Abstract]. Psychopharmacology, 203(1), 109-20. Retrieved from ... Anesthetic use. Since the introduction of anesthesia, hallucinations and dreams that are blurred with reality have often been ... Propofol: People who have been given this anesthetic drug have reported hallucinations and dreams that are "pleasant" and may ...
  https://www.medicalnewstoday.com/articles/297625.php?iacp
*  Medicine - Scientific American
Is the Ketamine Boom Getting out of Hand?. The anesthetic and party drug offers depression patients new hope, but some clinics ...
  https://www.scientificamerican.com/medicine/
*  Therapeutic infusions of ketamine: do the psychoactive effects matter? - PubMed - NCBI
Sub-anesthetic ketamine infusions may benefit a variety of psychiatric disorders, including addiction. Though ketamine ... Ketamine led to significantly greater acute mystical-type effects (by HMS) relative to the active control lorazepam; ketamine ... for ketamine-induced dissociation (CADSS score) or mysticism (HMS score), as well as infusion type (lorazepam vs. ketamine). ... Therapeutic infusions of ketamine: do the psychoactive effects matter?. Dakwar E1, Anerella C2, Hart CL3, Levin FR4, Mathew SJ5 ...
  https://www.ncbi.nlm.nih.gov/pubmed/24480515
*  CSR&D Funded Projects
Intravenous Sub-anesthetic Ketamine Treatment in Treatment-Resistant Depression. Merit Review. Shive, Carey . Cleveland, OH. ... Ketamine for Treatment Resistant Late-Life Depression. Merit Review. May, James M. Nashville, TN. Failure of the glutamate ... CAP-Ketamine for antidepressant resistant PTSD. Merit Review. Lad, Shivanand P. Durham, NC. Evaluation of Efficiency and ... Ketamine for The Rapid Treatment of Major Depression and Alcohol Use Disorder. Merit Review. ...
  https://www.research.va.gov/services/csrd/csrd_projects.cfm
*  I have a little hope again to help with this pain!! - Chronic Pain - HealingWell.com Forum
Ketamine is a really really strong anesthetic & analgesic. We commonly use it as an anesthetic (with the bonus of analgesic ... I did an internet search on low dose sub anesthetic ketamine infusions . It does seem to be helpful in cases of CRPS and RSD ... Have you ever taken Ketamine before? Please be careful and make sure you are monitored well during this event. I had Ketamine ... I'm not real sure about ketamine other than it rings bells for tonsillectomies back when I worked the floors. I'm sure your doc ...
  http://www.healingwell.com/community/default.aspx?f=16&m=1694285
*  Schenker E[au] - PubMed - NCBI
Sub-anesthetic ketamine modulates intrinsic BOLD connectivity within the hippocampal-prefrontal circuit in the rat. ... Species-conserved reconfigurations of brain network topology induced by ketamine.. Becker R, Braun U, Schwarz AJ, Gass N, ... Clozapine counteracts a ketamine-induced depression of hippocampal-prefrontal neuroplasticity and alters signaling pathway ... Acute ketamine challenge increases resting state prefrontal-hippocampal connectivity in both humans and rats. ...
  https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Schenker+E%5Bau%5D&dispmax=50
*  Antidepressants - What does Antidepressants stand for? The Free Dictionary
Why anesthetic ketamine produces a rapid antidepressant response. Roughly one in ten people told interviewers they had been ...
  https://acronyms.thefreedictionary.com/Antidepressants
*  General anesthetics
CNS Pharmacology General anesthetics Dr. Hiwa K. Saaed, H.D, M.Sc, Ph.D Department of Pharmacology & Toxicology College of ... Intravenous anesthetics/ ketamineKetamine (phencyclidine derivative) a short-acting, anesthetic, induces a dissociated state ... General anesthetics * 1. CNS Pharmacology General anesthetics Dr. Hiwa K. Saaed, H.D, M.Sc, Ph.D Department of Pharmacology & ... For inhaled anesthetics, higher CO removes anesthetic from the alveoli faster and thus slows the rate of rise in alveolar ...
  https://www.slideshare.net/Pharmacologist/2014-general-anesthetics
*  Cough Medicine Abuse by Teens - AHealthyMe - Blue Cross Blue Shield of Massachusetts
The effects of DXM have been compared to PCP and the anesthetic ketamine. All 3 are called dissociative substances. At high ...
  http://www.ahealthyme.com/Library/DiseasesConditions/Adult/Men/1,2617
*  Time, action and psychosis: Using subjective time to investigate the effects of ketamine on sense of agency - Semantic Scholar
In the present study we aimed to characterise the psychotomimetic effect of ketamine, a drug model for psychosis, on the ... It was shown that ketamine produced a disruption that closely resembled previous data from patients in the early, prodromal, ... Sub-Anesthetic Ketamine Modulates Intrinsic BOLD Connectivity Within the Hippocampal-Prefrontal Circuit in the Rat. *Natalia ... Ketamine perturbs perception of the flow of time in healthy volunteers. *Jennifer T Coull, Hannah Morgan, +5 authors Paul C ...
  https://www.semanticscholar.org/paper/Time%2C-action-and-psychosis%3A-Using-subjective-time-Moore-Cambridge/427fa2a340520d0eaa0499a82e7ac3d94d78b61d
*  Marijuana drug for epilepsy, Epidiolex, wins FDA approval - Business Insider
The anesthetic ketamine, for example, is prescribed this way for some hard-to-treat forms of depression.) ...
  https://www.businessinsider.com/marijuana-epilepsy-drug-approved-fda-2018-5
*  KAKEN - Research Projects | The effect of anesthetics on mesangial cells proliferation via protein kinase pathway. (KAKENHI...
We studied the effects of intravenous anesthetics ketamine and propofol on rat mesangial cell (MC) proliferation.. (1)Ketamine ... 3)Protein Kinase A inhibitor recoverd the inhibition of ketamine on MC proliferation.. (4)Moreover, anesthetics (halothane and ... Publications] Jimi N et.al: 'Inhibitory eddects of the intravenous anesthetic,ketamine,on rat mesangial cell prollferation' ... Publications] Jimi N., et al.: 'Inhibitory effect of the intravenous anesthetic, ketamine, on rat mesangial cell proliferation ...
  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09671595/
*  Frontiers | Hippocampal-Prefrontal Interactions in Cognition, Behavior and Psychiatric Disease | Frontiers in Systems...
2014). Sub-anesthetic ketamine modulates intrinsic BOLD connectivity within the hippocampal-prefrontal circuit in the rat. ... Frohlich, J., and van Horn, J. D. (2014). Reviewing the ketamine model for schizophrenia. J. Psychopharmacol. 28, 287-302. doi ... 2015). Acute ketamine challenge increases resting state prefrontal-hippocampal connectivity in both humans and rats. ... Antagonists of the N-methyl-D-aspartate receptor (NMDAR) such as ketamine can induce symptoms reminiscent of schizophrenia in ...
  https://www.frontiersin.org/articles/10.3389/fnsys.2015.00190/full
*  Eliminating opioids from anesthesia decreases post-surgery nausea, study shows | EurekAlert! Science News
Instead, patients received various combinations of magnesium, sub-anesthetic ketamine, lidocaine and ketorolac, depending on ...
  https://www.eurekalert.org/pub_releases/2017-10/asoa-eof101817.php
*  New Tools for Depression | Proto Magazine
ONE OF THE MOST promising recent discoveries is the use of the anesthetic ketamine and its derivatives. Ketamine blocks ... Ketamine was approved by the Food and Drug Administration in 1970 as a short-acting anesthetic, and the drug, which distorts ... In 2000, ketamine was tried for the first time with depressed patients. A single 40-minute intravenous infusion of the drug ... Among those receiving ketamine, 55% showed a robust reduction in suicidal thoughts in one day, versus 30% of those who got ...
  http://protomag.com/articles/new-tools-depression
*  Plus it
Rats were injected intraperitoneally with a cocktail of the anesthetic ketamine (100 mg/ml) and the muscle relaxant xylazine ( ... 2006) Frontal responses during learning predict vulnerability to the psychotogenic effects of ketamine: linking cognition, ...
  http://www.jneurosci.org/content/35/1/74
*  Chemistry News Articles: Chemistry 2011.org
Penn Medicine Researchers "Smell" New Receptors that Could Underlie the Many Actions of the Anesthetic Drug Ketamine. Penn ... Medicine researchers are continuing their work in trying to understand the mechanisms through which anesthetics work to elicit ...
  http://www.chemistry2011.org/news/PhysicalSciences/Chemistry/?Page=19