*  US20080008694A1 - Methods to prevent and treat diseases - Google Patents
SEQ ID NO:10), the entire FPR, or at least one soluble receptor, the truncated 17 amino acid loop of the FPR, pentoxifylline, ... It is one of the tachykinins, such as bradykinin, which have contractile effects. The protein sequence of Substance P is ... N-Formylmethionine (fMet) is an amino acid found in all living cells. It is a derivative of the amino acid methionine. It is a ... Spinorphin is an endogenous 7 amino acid peptide of Leu-Val-Val-Tyr-Pro-Trp-Thr (SEQ ID NO:3), which can be isolated from ...
  https://patents.google.com/patent/US20080008694A1/en
*  Expression of TAC1 in cancer - Summary - The Human Protein Atlas
Citric acid cycle related proteins. Disease related genes. Enzymes. FDA approved drug targets. G-protein coupled receptors. ... GO:0007217 [tachykinin receptor signaling pathway]. GO:0007218 [neuropeptide signaling pathway]. GO:0007267 [cell-cell ... The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide ( ... RNA-seq data in 17 cancer types are reported as median FPKM (number Fragments Per Kilobase of exon per Million reads), ...
  http://www.proteinatlas.org/ENSG00000006128-TAC1/pathology
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
A four amino-acid duplication in CmPH distinguishes between primitive acidic varieties and modern dessert melons. This ... We analyzed ChIP-Seq data and found that both Pou5f1 and Sox2 bind to mych and mycl1b control regions. The regulation of mych ... This system was also used for demonstrating the role of ROS in phosphorylation and activation of the EGF receptor as well as ... Although the piscine Tac3 gene encodes for two putative tachykinin peptides, the mammalian ortholog encodes for only one. The ...
  https://www.jove.com/visualize?author=Shifra%20Ben-Dor%20
*  Hematopoietic Growth Factor Inducible Neurokinin-1 Gene and Uses Thereof - Patent application
... amino acid sequence of SEQ ID NO:2, over the entire length of the recited amino acid sequences. [0126] The nucleotide sequences ... acid protein was aligned to the sequence of the NK-1 receptor. PredictProtein results were used to determine the ... 0009] The tachykinins are immune and hematopoietic modulators that belong to a family of peptides encoded by a single copy of ... Polypeptides may contain amino acids other than the gene-encoded amino acids. "Polypeptides" include amino acid sequences ...
  http://www.patentsencyclopedia.com/app/20110237519
*  Patent US8017131 - Clostridial toxin derivatives and methods for treating pain - Google Patents
... and the subsequent 17 amino acid sequences set forth in Table one can be similarly identified as SEQ ID NO:2 to SEQ ID NO:18. ... SEQ ID NO: 14, SEQ ID NO: 15, SEQ ID NO: 16, SEQ ID NO: 17, or SEQ ID NO: 18 that binds to a substance P receptor. ... A preferred group of transmission compounds can be selected from the tachykinin family of which substance P is a member. ... SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 10, ...
  http://www.google.com/patents/US8017131?dq=%22robert+sheehan%22
*  METHODS OF TREATMENT USING BIASED LIGANDS FOR RECEPTORS SUCH AS THE PTH RECEPTOR - Patent application
For example, there are numerous D amino acids or amino acids which have a different functional substituent then the amino acids ... TABLE-US-00003 1. SEQ ID NO: 1 TYPE 1 PARATHYROID HORMONE RECEPTOR [Homo sapiens] ACCESSION AAI10389 REFERENCE: Strausberg RL, ... with tachykinin neurokinin-1 receptors using [3-Prolinomethionine(11)]SP analogues. J Biol Chem 274:23770-23776. [0379] Samama ... acetic acid, propionic acid, glycolic acid, lactic acid, pyruvic acid, oxalic acid, malonic acid, succinic acid, maleic acid, ...
  http://www.patentsencyclopedia.com/app/20110178015
*  Protocols and Video Articles Authored by Peter Nagy (Translated to Norwegian)
Role of Tachykinin 1 and 4 Gene-derived Neuropeptides and the Neurokinin 1 Receptor in Adjuvant-induced Chronic Arthritis of ... Here, heterozygous sequence variants in LMNA, which result in single amino-acid substitutions, were identified in patients ... Using small RNA-seq, we also examined miRNA species putatively involved in SAT1 post-transcriptional regulation. A DSM-IV ... In this study, we analysed the involvement of tachykinins derived from the Tac1 and Tac4 genes, as well as the NK1 receptor in ...
  https://www.jove.com/author/Peter_Nagy?language=Norwegian
*  US7928059B2 - Use of neuropeptides for traumatic cartilage injury - Google Patents
A61K38/04-Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof ... "Impaired IL-1beta-induced neutrophil accumulation in tachykinin NK1 receptor knockout mice." British Journal of Pharmacology, ... SEQ. ID. NO: 1), reverse: 5′-ACT GGA TTC CTT GAA CGT C-3′ (SEQ. ID. NO: 2), length 283 bp; Cathepsin K: forward: 5′-TGC GAC CGT ... A61K38/04-Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof ...
  https://patents.google.com/patent/US7928059B2/en
*  Seiji Nishino | Stanford Medicine Profiles
Specific cholinergic agonists and antagonists, and excitatory or inhibitory amino acid neurotransmitter receptor agonists, were ... We identified two neuropeptide precursor molecules, Tachykinin precursor 1 (TAC1) and Proenkephalin (PENK), that together with ... RNA-seq, and HITS-CLIP. Importantly, the majority of the Mbnl2-regulated exons examined were similarly misregulated in DM. We ... such as benzodiazepines on gamma amino butyric acid (GABA)(A) receptors, and amphetamine-like stimulants on monoaminergic ...
  https://med.stanford.edu/profiles/seiji-nishino
*  METHODS OF TREATING INFLAMMATORY PAIN - Patent application
... identical in amino acid sequence to SEQ ID NO: 1 and a VL domain that is at least 90% identical in amino acid sequence to SEQ ... FcγRII receptors include FcγRIIA (an "activating receptor") and FcγRIIB (an "inhibiting receptor"), which have similar amino ... 0136] (xii) a tachykinin (NK) antagonist, particularly an NK-3, NK-2 or NK-1 antagonist, e.g. (αR,9R)-7-[3,5-bis( ... identical in amino acid sequence to SEQ ID NO: 19 and a VL domain that is at least 90% identical in amino acid sequence to SEQ ...
  http://www.patentsencyclopedia.com/app/20130295088
*  METHOD FOR DETERMINING THE BINDING OF A GIVEN COMPOUND TO A MEMBRANE RECEPTOR - Patent application
SEQ ID No.1) in which X is any amino acid and of a bi-arsenic compound. These bi-arsenic compounds can easily be labeled with ... Receptors of substance P NK1 tachykinin neurokinin A NK2 neurokinin B NK3 Thyroliberin receptor thyrotropin-releasing TRH1 ... receptors angiotensin AT2 Apelin receptors apelin APJ Bile acid receptors bile acids GPBA Bombesin receptors neuromedin B BB1 ... receptors FPR3 FPR1 Receptors of free Long-chain carboxylic FFA1 fatty acids acids FFA3 FFA2 GPR42 Galanin receptors galanin ...
  http://www.patentsencyclopedia.com/app/20120190048
*  15th week of 2010 patent applcation highlights part 38
FOXP3 PEPTIDE VACCINE - The present invention provides Foxp3 peptides comprising the amino acid sequence of SEQ ID NOs: 3-5, 7- ... Exemplary neuropeptides include tachykinins, such as Substance P, Substance K, and the like, as well as calcitonin gene-related ... Natural water soluble extracts for the inhibition of alpha-1-adrenergic receptors - The present invention discloses therapeutic ... and Foxp3 peptides comprising the above-mentioned amino acid sequences in which 1, 2, or several amino acids are substituted or ...
  http://www.patentsencyclopedia.com/hgl/04-15-10/04-15-10_38
*  A secretagogin locus of the mammalian hypothalamus controls stress hormone release | The EMBO Journal
Local amino acid transmitter synthesis in, and release from, nerve endings in the external layer of the median eminence may yet ... Tang F, Barbacioru C, Wang Y, Nordman E, Lee C, Xu N, Wang X, Bodeau J, Tuch BB, Siddiqui A, Lao K, Surani MA (2009) mRNA‐Seq ... Nr3c1 encodes a glucocorticoid receptor (nuclear receptor subfamily 3, group C member 1) (van Rossum et al, 2004). Nr3c1 can ... tachykinin 1 (n = 9), cocaine‐ and amphetamine‐regulated transcript (CART; n = 24), neurotensin S (n = 2), VGF nerve growth ...
  http://emboj.embopress.org/content/34/1/36
*  VEGFR - Selective suppression of excessive GluN2C expression
Mutations by displacement of one amino acid residue could greatly impact the rate and house of amyloid formation. These ... Tachykinin NK1 Receptors *Tachykinin NK2 Receptors *Tachykinin NK3 Receptors *Tachykinin Receptors *Tankyrase ... panel of transcription factors by ChIP-Seq following LPS excitement. Their data recommended that E2F-1 and RelA are normal ... receptor family of receptor tyrosine kinases.This protein has no ligand binding domain of its own and therefore cannot bind ...
  http://health-media.net/category/vegfr/
*  Purification and mass spectrometric characterization of human CXCR4 - UBC Library Open Collections
... the first two amino acids Lys-1 and Pro-2 on SDF-1 activate the receptor. When one or both of these amino acids are 15 removed ... Extracellular sequences from the crossliriked receptor, indicated in blue text were sequenced by tandem mass spectrometry. seq ... The use ofphotolabeled peptides to localize the substance-P-binding site in the human neurokinin-1 tachykinin receptor. Eur. J ... Synthetic peptides (9 amino acids long, 2 amino acid overlap) spanning the C-terminal 45 amino acids of CXCR4 were coupled to a ...
  https://open.library.ubc.ca/cIRcle/collections/ubctheses/24/items/1.0067000