PfEMP1-DBL1α amino acid motifs in severe disease states of Plasmodium falciparum malaria | PNAS
... severe motifs; M, mild motifs; C, cerebral malaria motifs; N, severe malaria NUD motifs; NS, nonsevere malaria NUD motifs; R, ... Specific PfEMP1-DBL1α amino acid motifs correlated with rosetting and severe malaria, with motif location corresponding to ... Amino acids involved in receptor binding are indicated by blue dots, and amino acids essential for binding are represented by ... PfEMP1-DBL1α amino acid motifs in severe disease states of Plasmodium falciparum malaria. Johan Normark, Daniel Nilsson, Ulf ...http://www.pnas.org/content/104/40/15835
The Amino Acid Motif L/IIxxFE Defines a Novel Actin-Binding Sequence in PDZ-RhoGEF
Endophytic Life Strategies Decoded by Genome and Transcriptome Analyses of the Mutualistic Root Symbiont Piriformospora indica
Amino acid motifs in P. indica In order to screen the genome of P. indica for known and unknown motifs in the amino acid ... A search for motifs (Table S12 and S13) in the amino acid sequences of these heterogeneous proteins identified a group of 25 ... amino acid permeases, transmembrane amino acid transporter proteins, nucleobase cation symporters, ABC-2 type transporters, and ... 1) Secreted proteins were predicted using TargetP and SignalP as described in material and methods, amino acid motifs in P. ...http://pubmedcentralcanada.ca/pmcc/articles/PMC3192844/
Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG.
Amino Acid Motifs. Amino Acid Sequence. Apoptosis Regulatory Proteins / metabolism*. Autophagy. Class III Phosphatidylinositol ... Another prominent feature of the Beclin 1 CC structure is the unusually high composition of charged amino acid residues, as ... Beclin 1 self-association is independent of autophagy induction by amino acid deprivation and rapamycin treatment. J. Cell ... are directly involved in Beclin 1-Atg14L interaction because mutating these amino acids to hydrophobic leucine residue nearly ...http://www.biomedsearch.com/nih/Imperfect-interface-Beclin1-coiled-coil/22314358.html
A survey of machine learning methods for secondary and supersecondary protein structure prediction. - NextBio article
Amino Acid Motifs Artificial Intelligence Computational Biology Models, Molecular Protein Structure, Secondary Proteins ...http://www.nextbio.com/b/search/article.nb?id=22987348
A Screen for New Trithorax Group Genes Identified little imaginal discs, the Drosophila melanogaster Homologue of Human...
... a bipartite nuclear localization signal is found at amino acids 1599-1616. Each of these amino acid motifs is found in human ... This domain has a previously described amino acid motif called ARID (AT-rich interaction domain; Herrscheret al. 1995). Among ... Amino acid motifs were determined using the Profilescan program and PsortII programs. Protein alignments were performed on the ... The protein contains a number of amino acid motifs found in both trithorax and Polycomb group genes. It contains an N-terminal ...http://www.genetics.org/content/156/2/645
Effects of recombinant N-terminal proteins on rates of | Open-i
Protein Interaction Domains and Motifs/physiology*. Minor. *Actin Cytoskeleton/genetics/metabolism. *Amino Acid Motifs/genetics ... Mentions: To assess whether the motif or C1 affected rates of force activation in addition to their effects on steady-state ... Mentions: To assess whether the motif or C1 affected rates of force activation in addition to their effects on steady-state ... These results suggest that the C1 domain plus the motif constitute a functional unit of MyBP-C that can activate the thin ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2571974_jgp1320575f07&req=4
Silencing SUMO E2 enzyme Ubc9 represses DENV replicatio | Open-i
Amino Acid Motifs. *Amino Acid Sequence. *Animals. *Cell Line. *Cells, Cultured. *Dengue/genetics/metabolism/virology ... we found that the SUMO acceptor sites are located in the N-terminal domain of NS5 and that a putative SUMO-interacting motif ( ... we found that the SUMO acceptor sites are located in the N-terminal domain of NS5 and that a putative SUMO-interacting motif ( ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4836324_zjv9990915840001&req=4
Overexpression of eYFP-PIAS4 disrupts SUMO pathway home | Open-i
Amino Acid Motifs. *Amino Acid Sequence. *Cell Line. *DNA Replication. *DNA, Viral ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4836348_zjv9990916200004&req=4
Stabilin-1 localizes to endosomes and the trans-Golgi network in human macrophages and interacts with GGA adaptors.
Amino Acid Motifs/immunology, Antigens; CD/immunology, Brefeldin A/pharmacology, Carrier Proteins/immunology/metabolism, Cell ...http://uu.diva-portal.org/smash/record.jsf?pid=diva2:96016
Glycogen synthase kinase 3beta interaction protein functions as an A-kinase anchoring protein - Publikationsserver der...
Amino Acid Motifs/physiology. MESH. Cell Line, Tumor. MESH. Cyclic AMP-Dependent Protein Kinases/metabolism. MESH. ... Our bioinformatics and peptide array screening approaches based on this signature motif identified GSKIP (glycogen synthase ... of the interactions between the dimerization and docking domain and various PKA-binding domains yielded a generalized motif ...https://epub.uni-regensburg.de/30633/
Amphioxus (Branchiostoma floridae) has orthologs of vertebrate odorant receptors | BMC Evolutionary Biology | Full Text
Key amino acid motifs. To identify amino acid motifs common in vertebrate and B. floridae ORs, we constructed an alignment of ... By exposing conserved amino acid motifs and testing the ability of those motifs to discriminate between ORs and non-OR GPCRs, ... from which a list of candidate amino acid motifs was generated. To determine whether these motifs were present in ORs, non-ORs ... Conserved amino acid motifs have previously been noted in alignments of human, mouse and zebrafish OR sequences [13, 27, 30, 31 ...https://0-bmcevolbiol-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/1471-2148-9-242
The diverse evolutionary pattern of ESEs and ESSs in as | Open-i
Amino Acid Motifs. *Animals. *DNA Mutational Analysis. *Enhancer Elements, Genetic. *Gene Silencing ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC3091315_gb-2009-10-11-r120-3&req=4
The distribution of mIMRs in the immature Gag protein [ | Open-i
The gag gene of HIV-1 [GenBank:K03455] was selected for the study because its protein motifs and structural components are well ... Nucleic Acid Conformation*. *Protein Conformation*. *Tandem Repeat Sequences/genetics*. *gag Gene Products, Human ... The gag gene of HIV-1 [GenBank:K03455] was selected for the study because its protein motifs and structural components are well ... The distribution of IMRs and their relationship to structural and functional motifs in the protein that they translate, suggest ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2211468_1743-422X-4-113-1&req=4
Conserved expression patterns associated with functiona | Open-i
Conserved expression patterns associated with functional binding site motif variants (BSMVs).The y-axis of each plot is the ... Amino Acid Motifs. *Binding Sites. *Computational Biology/methods. *Genome, Fungal. *Genomics. *Models, Statistical ... Bottom Line: To accomplish this, we statistically detect motif variants with effects that differ among environments.We find ... Bottom Line: To accomplish this, we statistically detect motif variants with effects that differ among environments.We find ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC3285675_pone.0032274.g003&req=4
A 20 amino acid motif in the β subunit loop is sufficient for clustering. A , CD4-β loop chimeras were generated with either ... First, we tested CD4-chimeras containing the first (amino acids 333-406) or second halves (aa 407-469) of the β loop (Fig. 2). ... By making deletions in the β loop we defined a 20 amino-acid sequence that is sufficient for clustering. The sequence contains ... Using chimeric proteins consisting of CD4 fused to each of the AChR subunit intracellular loops, we identify a 20 amino acid ...http://www.jneurosci.org/content/28/45/11468
Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2 |...
Regulation by heme of mitochondrial protein transport through a conserved amino acid motif. Science 1993;259(5094):522-525. ... Bach1 possesses at least 4 Cys-Pro motifs (CP motifs)21,22 involved in heme-binding. Heme binds to Bach1 to inhibit its DNA ... 5 Although amino acid residues involved in the heme binding represented by the 432-nm peak remain to be identified, our ... Involvement of heme regulatory motif in heme-mediated ubiquitination and degradation of IRP2. Mol Cell 2005;19(2):171-181. ...http://www.bloodjournal.org/content/117/20/5438?ijkey=2a319d5cc8692e839765f28e4f62f5d43c7eeea1&keytype2=tf_ipsecsha&sso-checked=true
Malleability of protein folding pathways : a simple reason for complex behaviour.
Amino Acid Motifs, Models; Molecular, Protein Conformation, Protein Folding, Proteins/*chemistry/*metabolism, Signal ...http://su.diva-portal.org/smash/record.jsf?faces-redirect=true&language=sv&searchType=SIMPLE&query=&af=%5B%5D&aq=%5B%5B%5D%5D&aq2=%5B%5B%5D%5D&aqe=%5B%5D&pid=diva2%3A188993&noOfRows=50&sortOrder=author_sort_asc&sortOrder2=title_sort_asc&onlyFullText=false&sf=all
Inhibition of the binding activity of recombinant PB2 w | Open-i
Amino Acid Motifs/genetics. *Amino Acid Sequence. *Animals. *Binding Sites/genetics. *Cell Line, Tumor ... In contrast, anacardic acid and garcinol drastically inhibited the interaction, and concentrations of anacardic acid greater ... In contrast, anacardic acid and garcinol drastically inhibited the interaction, and concentrations of anacardic acid greater ... p , 0.01; DMSO versus anacardic acid. †, p , 0.05 and ††, p , 0.01; DMSO versus garcinol. Mentions: One HAT, p300/cAMP-response ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4155666_zbc0411495550004&req=4
Frontiers | Microbial effectors target multiple steps in the salicylic acid production and signaling pathway | Plant Science
Among these, salicylic acid signaling is an important pathway because of its ability to trigger plant cell death. As biotrophic ... Here we review the strategies prokaryotic pathogens have developed to target salicylic acid biosynthesis and signaling, and ... Here we review the strategies prokaryotic pathogens have developed to target salicylic acid biosynthesis and signaling, and ... they have evolved efficient strategies to downregulate salicylic acid signaling by virulence effectors, which can be proteins ...https://www.frontiersin.org/articles/10.3389/fpls.2015.00349/full
1A ). In almost all the peptides, the amino acid motif GGL was seen. ... A, amino acid sequences of peptide inserts identified with the anti-CEA antibody Col-1 in biopanning procedure were subjected ... Deduced amino acid sequences were subjected to the multiple algorithm of the Vector NTI Suite and a phylogenetic tree was ... nonessential amino acids, and 1 mmol/L sodium pyruvate (Invitrogen). Cells were loosened with Na-EDTA and 107 tumor cells were ...http://clincancerres.aacrjournals.org/content/13/21/6501
... we observed motif sharing among insert amino acid sequences of tumor-homing clones and identification of those motifs in human ... The highlighted motif-sharing regions having amino acids with exact matches are shown in white letters and those with ... Several amino acid motifs were identified among tumor-homing phage clones, indicating nonrandom tumor accumulation. Phage ... Table 2 shows amino acid sequences, their frequency, and possible motifs of phage clones obtained from surgically harvested ...http://cancerres.aacrjournals.org/content/66/15/7724
Vibrational spectroscopy of a non-aromatic amino acid-based model peptide: Identification of the gamma-turn motif of the...
Vibrational spectroscopy of a non-aromatic amino acid-based model peptide: Identification of the gamma-turn motif of the ...http://repository.ubn.ru.nl/handle/2066/98878
"DC3, the smallest subunit of the Chlamydomonas flagellar outer dynein " by Diane M. Casey, Toshiki Yagi et al.
Amino Acid Motifs; Amino Acid Substitution; Animals; Calcium; Calcium-Binding Proteins; Chlamydomonas; Dynein ATPase; Flagella ...https://escholarship.umassmed.edu/gsbs_sp/187/
"Regulation of survivin stability by the aryl hydrocarbon receptor-inte" by Byoung Kang and Dario C. Altieri
This interaction is mediated by the carboxyl-terminal end of AIP, which contains three tetratricopeptide motifs, and involves ... Amino Acid Motifs; Amino Acid Sequence; Cell Death; Hela Cells; Humans; Microtubule-Associated Proteins; Molecular Sequence ... This interaction is mediated by the carboxyl-terminal end of AIP, which contains three tetratricopeptide motifs, and involves ...https://escholarship.umassmed.edu/oapubs/676/