*  UniProtKB/SwissProt variant VAR 032277
It can be associated with cerebral amyloid angiopathy. Alzheimer disease is a neurodegenerative disorder characterized by ... Indicates the amino acid change of the variant. The one-letter and three-letter codes for amino acids used in UniProtKB/Swiss- ... Alzheimer disease 1 (AD1) [MIM:104300]: A familial early-onset form of Alzheimer disease. ... V -> K. Decreased amyloid-beta protein 42/total amyloid-beta ratio.. Mutagenesis. 717 - 717. V -> M. Increased amyloid-beta ...
  https://web.expasy.org/variant_pages/VAR_032277.html
*  ALZFORUM | NETWORKING FOR A CURE
Interestingly, substitution of Asp-23 by Asn is associated with a familial form of early onset cerebral amyloid angiopathy in ... Predicted intermolecular associations offer explanations of how mutations producing amino acid substitutions at Glu-22 (the ... Amyloid beta -protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways. Proc Natl Acad Sci U S A. ... Tycko model provides a wonderful theoretical foundation for the design of experiments to test the roles of specific amino acids ...
  http://www.alzforum.org/papers/structural-model-alzheimers-beta-amyloid-fibrils-based-experimental-constraints-solid-state
*  Patent US6331296 - Food additives which affect conformationally altered proteins - Google Patents
Aβ peptide in amyloid plaques of Alzheimer's disease and cerebral amyloid angiopathy (CAA); α-synuclein deposits in Lewy bodies ... The conformationally altered protein appears in another conformation which has the same amino acid sequence. In general, the ... and familial amyloid polyneuropathy (FAP) (Kelly (1996) Curr Opin Strut Biol 6(1):11-7). The cause of amyloid formation in FAP ... The term "cerebral amyloid angiopathy" (abbreviated herein as CAA) as used herein refers to a condition associated with ...
  http://www.google.com/patents/US6331296?dq=6272333
*  List of MeSH codes (C16) - Wikipedia
... familial MeSH C16.320.565.100.050 --- amyloid neuropathies, familial MeSH C16.320.565.100.160 --- cerebral amyloid angiopathy, ... amino acid metabolism, inborn errors MeSH C16.320.565.066.102 --- albinism MeSH C16.320.565.066.102.090 --- albinism, ocular ... cerebral amyloid angiopathy, familial MeSH C16.320.565.150.175 --- citrullinemia MeSH C16.320.565.150.320 --- galactosemias ... amyloid neuropathies, familial MeSH C16.320.400.150 --- canavan disease MeSH C16.320.400.200 --- cockayne syndrome MeSH C16.320 ...
  https://en.wikipedia.org/wiki/List_of_MeSH_codes_(C16)
*  Anti-beta Amyloid 1-40 antibody [BDI350] (ab20068)
Mouse monoclonal beta Amyloid 1-40 antibody [BDI350] validated for WB, ELISA, IHC, ICC and tested in Human. Referenced in 1 ... Patients develop cerebral hemorrhage because of the severe cerebral amyloid angiopathy. Parenchymal amyloid deposits are rare ... However, additional amino acids either N- or C-terminal to the NPXY motif are often required for complete interaction. The PID ... Defects in APP are the cause of Alzheimer disease type 1 (AD1) [MIM:104300]. AD1 is a familial early-onset form of Alzheimer ...
  http://www.abcam.com/beta-amyloid-1-40-antibody-bdi350-ab20068.html
*  Anti-beta Amyloid 1-40 antibody (ab17295) | Abcam
Rabbit polyclonal beta Amyloid 1-40 antibody validated for WB, ELISA and tested in Human and Mouse. Immunogen corresponding to ... Patients develop cerebral hemorrhage because of the severe cerebral amyloid angiopathy. Parenchymal amyloid deposits are rare ... However, additional amino acids either N- or C-terminal to the NPXY motif are often required for complete interaction. The PID ... Defects in APP are the cause of Alzheimer disease type 1 (AD1) [MIM:104300]. AD1 is a familial early-onset form of Alzheimer ...
  http://www.abcam.com/beta-amyloid-1-40-antibody-ab17295.html
*  List of MeSH codes (C18) - Wikipedia
... cerebral amyloid angiopathy MeSH C18.452.090.100.160 --- cerebral amyloid angiopathy, familial MeSH C18.452.100.100 --- brain ... amino acid metabolism, inborn errors MeSH C18.452.648.066.102 --- albinism MeSH C18.452.648.066.102.090 --- albinism, ocular ... familial MeSH C18.452.090.075.050 --- amyloid neuropathies, familial MeSH C18.452.090.075.160 --- cerebral amyloid angiopathy, ... familial MeSH C18.452.648.100.050 --- amyloid neuropathies, familial MeSH C18.452.648.100.160 --- cerebral amyloid angiopathy, ...
  https://en.wikipedia.org/wiki/List_of_MeSH_codes_(C18)
*  Patent US5837672 - Methods and compositions for the detection of soluble β-amyloid peptide - Google Patents
Soluble β-amyloid peptide (βAP) is measured in biological fluids at very low concentrations, typically in the range from 0.1 ng ... amyloid) plaques and the amyloid deposits in small cerebral and meningeal blood vessels (amyloid angiopathy). βAP can occur in ... such as the junction region consisting of amino acid residues 13-28 and the amino terminus consisting of amino acid residues 1- ... Citron, M., et al., Mutation of the Beta amyloid precursor protein in familial Alzheimer s disease increases Beta protein ...
  http://www.google.com/patents/US5837672?dq=6519629
*  METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS - Patent application
... cerebral amyloid angiopathies, cerebral palsy, chronic fatigue syndrome, corticobasal degeneration, conditions due to ... 4-597 amino acids, preferably 4-400 amino acids, preferably 4-300 amino acids, preferably 4-200 amino acids, preferably 4-100 ... fatal familial insomnia, Gerstmann-Straussler-Scheinker disease and other transmissible spongiform encephalopathies, prion ... acetic acid, propionic acid, glycolic acid, lactic acid, pyruvic acid, oxalic acid, malonic acid, succinic acid, maleic acid, ...
  http://www.patentsencyclopedia.com/app/20090118135
*  Recombinant Human beta Amyloid 1-42 protein (ab82795)
Recombinant Human beta Amyloid 1-42 protein Full length protein datasheet (ab82795). Abcam offers quality products including ... Patients develop cerebral hemorrhage because of the severe cerebral amyloid angiopathy. Parenchymal amyloid deposits are rare ... However, additional amino acids either N- or C-terminal to the NPXY motif are often required for complete interaction. The PID ... Defects in APP are the cause of Alzheimer disease type 1 (AD1) [MIM:104300]. AD1 is a familial early-onset form of Alzheimer ...
  http://www.abcam.co.jp/recombinant-human-beta-amyloid-1-42-protein-ab82795.html
*  beta Amyloid 1-40抗体[BDI350]| Abcam中国
... beta Amyloid 1-40抗体经WB,ICC验证,可与人样本反应。1篇 ... 购买beta Amyloid 1-40小鼠单克隆抗体[BDI350](ab20068), ... Defects in APP are the cause of cerebral amyloid angiopathy APP ... However, additional amino acids either N- or C-terminal to the NPXY motif are often required for complete interaction. The PID ... Defects in APP are the cause of Alzheimer disease type 1 (AD1) [MIM:104300]. AD1 is a familial early-onset
  http://www.abcam.cn/beta-amyloid-1-40-antibody-bdi350-ab20068.html
*  Anti-beta Amyloid 1-40 抗体 (ab17295) | アブカム
"ウサギ・ポリクローナル抗体 ab17295 交差種: Ms,Hu 適用: WB,ELISA…beta Amyloid 1-40抗体一覧…画像、プロトコール、文献などWeb上の情報 ... Patients develop cerebral hemorrhage because of the severe cerebral amyloid angiopathy. Parenchymal amyloid deposits are rare ... However, additional amino acids either N- or C-terminal to the NPXY motif are often required for complete interaction. The PID ... Defects in APP are the cause of Alzheimer disease type 1 (AD1) [MIM:104300]. AD1 is a familial early-onset
  http://www.abcam.co.jp/beta-amyloid-1-40-antibody-ab17295.html
*  beta Amyloid 1-40抗体|Abcam中国|Anti-beta Amyloid 1-40抗体(ab17295)
beta Amyloid 1-40兔多克隆抗体(ab17295)可与小鼠, 人样本反应并经WB, ELISA实验严格验证 ... Patients develop cerebral hemorrhage because of the severe cerebral amyloid angiopathy. Parenchymal amyloid deposits are rare ... However, additional amino acids either N- or C-terminal to the NPXY motif are often required for complete interaction. The PID ... Defects in APP are the cause of Alzheimer disease type 1 (AD1) [MIM:104300]. AD1 is a familial early-onset
  http://www.abcam.cn/beta-amyloid-1-40-antibody-ab17295.html
*  Methods and Compositions Related to Delivery of Chemical Compounds to Invertebrate Embryos - Patent application
0090]The protein encoded by SEQ ID NO: 2 is Amyloid A, which is associated with Cerebral Amyloid Angiopathy. Cerebral Amyloid ... For example, there are numerous D amino acids or amino acids which have a different functional substituent then the amino acids ... fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Two transcript variants encoding ... Amino Acid Abbreviations Amino Acid Abbreviations alanine AlaA allosoleucine AIle arginine ArgR asparagine AsnN aspartic acid ...
  http://www.patentsencyclopedia.com/app/20080276327
*  Alzheimer's Disease Cell Bio - Cell Biology of Disease and Exercise
... and cerebral amyloid angiopathy (CAA).[12] The Swedish mutation results in a double amino acid substitution of lysine to ... Lantos PL, Luthert PJ, Hanger D, Anderton BH, Mullan M, Rossor M. Familial Alzheimer's disease with the amyloid precursor ... Cerebral Amyloid Angiopathy. Cerebral amyloid angiopathy (CAA) associated with AD is defined as accumulation of Aβ in the ... Amyloid-beta Plaques. Amyloid Precursor Protein (APP). The amyloid precursor protein (APP or AβPP) contains the amyloid-β (Aβ) ...
  http://pt851.wikidot.com/alzheimer-s-disease-cell-bio
*  Colorado Surveillance Program for Chronic Wasting Disease Transmission to Humans (TWO SUSPECT CASES)
cerebral amyloid angiopathy in widespread areas of the brain. Plaque-type and vascular amyloid. was immunohistochemically ... 21 kDa and 19 kDa, resulting from cleavage around amino acids 82 and 97, respectively. Methods We generated anti-PrP monoclonal ... GSS, FFI, Familial/Genetic CJD, and or the sporadic FFI that is not genetic, and don't ask me why ??? does not make sense to me ... but if you have a strain of genetic/familial TSE i.e. FFI, and then you classify a sub-type of that strain that use to be ...
  http://www.vegsource.com/talk/madcow/messages/1001271.html
*  Amyloid-Beta: A Crucial Factor in Alzheimer's Disease - FullText - Medical Principles and Practice 2015, Vol. 24, No. 1 -...
In AD, the dysregulation of the amyloid-beta (Aβ) level leads to the appearance of seni ... Aβ that accumulates along cerebral blood vessels is known as cerebral amyloid angiopathy. This is frequently seen in AD cases ... α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor trafficking are influenced by the soluble form of Aβ [46]. Aβ ... the main focus of modeling studies is on amyloid deposition [101]. After the discovery of familial AD mutations in APP, ...
  https://www.karger.com/Article/FullText/369101
*  Anti-beta Amyloid 抗体 [DE2B4] (ab11132) | アブカム
... deposition in the cerebral vessels, resulting in cerebral amyloid angiopathy. Amyloid is not found outside the nervous system. ... Synthetic peptide, corresponding to amino acids 1-17 of Human beta Amyloid. ... Defects in APP are the cause of Alzheimer disease type 1 (AD1) [MIM:104300]. AD1 is a familial early-onset form of Alzheimer ... Patients develop cerebral hemorrhage because of the severe cerebral amyloid angiopathy. Parenchymal amyloid deposits are rare ...
  http://www.abcam.co.jp/beta-amyloid-antibody-de2b4-ab11132.html
*  1x7s - Proteopedia, life in 3D
Characterization of a transthyretin-related amyloid fibril protein from cerebral amyloid angiopathy in type I familial amyloid ... Revised analysis of amino acid replacement in a prealbumin variant (SKO-III) associated with familial amyloidotic ... Categories: Human , Damas, A M , Macedo-Ribeiro, S , Neto-Silva, R M , Pereira, P J.B , Saraiva, M J , Amyloid , Familial ... Yamamoto K, Hsu SP, Yoshida K, Ikeda S, Nakazato M, Shiomi K, Cheng SY, Furihata K, Ueno I, Yanagisawa N. Familial amyloid ...
  http://proteopedia.org/wiki/index.php/1x7s
*  Full text] Role of apolipoprotein E in neurodegenerative diseases | NDT
... regulating amyloid-β aggregations and clearances in the brain. Several APOE isoforms with major structural differences were ... APOE binds to cell-surface receptors to deliver lipids and to the hydrophobic amyloid-β peptide, ... amino acid residues 225-299).22 These domains are connected to each other by a hinge region (amino acid residues 166-224).22 ... amyloid plaques, white-matter lesions, and cerebral amyloid angiopathy.58 ...
  https://www.dovepress.com/role-of-apolipoprotein-e-in-neurodegenerative-diseases-peer-reviewed-fulltext-article-NDT
*  Amyloid beta - Wikipedia
Amyloid beta may be primarily vascular, as in cerebral amyloid angiopathy, or in senile plaques in white matter. One sensitive ... Amyloid beta (Aβ or Abeta) denotes peptides of 36-43 amino acids that are crucially involved in Alzheimer's disease as the main ... However, familial Alzheimer disease is likely to result from altered proteolytic processing. The gene for the amyloid precursor ... while Aβ can also form the aggregates that coat cerebral blood vessels in cerebral amyloid angiopathy. The plaques are composed ...
  https://en.wikipedia.org/wiki/Amyloid_beta
*  Indian Patents. 255986:SUBSTITUTED N-PHENYL BENZAMIDES
... hereditary cerebral hemorrhage with amyloidosis of the Dutch type, Nieman-Pick disease type C, cerebral p-amyloid angiopathy, ... As used herein, the term "amino acid" refers to a-amino acids which are racemic, or of either the D- or L-configuration. The ... the amyloid associated with senile cardiac amyloidosis and Familial Amyloidotic Polyneuropathy (where the specific amyloid is ... protein selected from the group of Ap amyloid, AA amyloid, AL amyloid, IAPP. 87. amyloid, PrP amyloid, a2-microglobulin amyloid ...
  http://www.allindianpatents.com/patents/255986-substituted-n-phenyl-benzamides
*  APP polyclonal antibody - (PAB9763) - Products - Abnova
A synthetic peptide corresponding to amino acids 653-662 of human APP. (PAB9763) - Products - Abnova ... cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [ ... A synthetic peptide corresponding to amino acids 653-662 of human APP. ... A4 amyloid protein,amyloid beta A4 protein,amyloid-beta protein,beta-amyloid peptide,cerebral vascular amyloid peptide, ...
  http://www.abnova.com/products/products_detail.asp?catalog_id=PAB9763
*  List of OMIM disorder codes - Wikipedia
VLDLR Cerebral amyloid angiopathy; 105150; CST3 Cerebral amyloid angiopathy, Dutch, Italian, Iowa, Flemish, Arctic variants; ... CYP19A1 Aromatic L-amino acid decarboxylase deficiency; 608643; DDC Arrhythmogenic right ventricular dysplasia 1; 107970; TGFB3 ... PTHR1 Familial cold autoinflammatory syndrome 2; 611762; NALP12 Familial Mediterranean fever, AD; 134610; MEFV Familial ... FREM1 Bile acid malabsorption, primary; 613291; SLC10A2 Bile acid synthesis defect, congenital, 2; 235555; AKR1D1 Bile acid ...
  https://en.wikipedia.org/wiki/List_of_OMIM_disorder_codes
*  Impact of Amyloid Imaging on Drug Development in Alzheimer's Disease
Amyloid plaques are predominantly comprised of insoluble amyloid-beta (Aβ) peptides, mostly 40 or 42 amino acids in length, ... that may be related to the presence of cerebral amyloid angiopathy [85]. A report on a subset of patients suggested that ... cause early-onset or familial forms of AD [28,29,30]. Further genetic support for the amyloid cascade hypothesis comes from the ... Keywords: Amyloid imaging, amyloid-beta, Aβ, PiB, Alzheimer's disease, anti-amyloid therapy ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2078205/?lang=en-ca