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*  gq g11 gtp binding protein alpha subunits
Research Grants about gq g11 gtp binding protein alpha subunits ... gtp binding protein beta subunits*estrenes*calcium channels*gtp ... heterotrimeric gtp binding proteins , gtp binding protein alpha subunits , gq g11 gtp binding protein alpha subunits ... gtp binding protein alpha subunits*cyclic amp*knockout mice*g12 g13 gtp binding protein alpha subunits*patch clamp techniques* ... gq g11 gtp binding protein alpha subunits. Summary. Summary: A family of heterotrimeric GTP-binding protein alpha subunits that ...
  https://www.labome.org/topics/chemicals/and/peptides/intracellular/heterotrimeric/gtp/gq-g11-gtp-binding-protein-alpha-subunits-12352.html
*  Coatomer beta subunit, C-terminal (IPR011710) | InterPro | EMBL-EBI
We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their ... InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites ... which are small GTP-binding proteins. Coatomer complexes are hetero-oligomers composed of at least an alpha, beta, beta', gamma ... This entry represents the C-terminal domain of the beta subunit from coatomer proteins (Beta-coat proteins). The C-terminal ...
  http://www.ebi.ac.uk/interpro/entry/IPR011710
*  KAKEN - Research Projects | Qualitative change of GTP-binding protein. (KAKENHI-PROJECT-02670084)
... an experiment about dissociation of the trimer of the three alpha beta gamma-subunits into alpha -subunits and beta gamma - ... Publications] Y. Watanabe: 'GTP-binding protein, protein kinase.' Hirokawa Shoten, Lecture of Neuroscience.. *. Description. 「研 ... GTP-binding Protein / lithium / Protein kinase / phosphorylation / Qualitative Change / ADP-ribosylation / Pertussis Toxin / ... of Gi protein by cyclic AMP-dependent protein kinase inhibits its dissociation into alpha-subunits and betaalpha-subunits by Mg ...
  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-02670084/
*  Gene Report for G00001504 - Genes2Cognition Neuroscience Research Programme
The heterotrimeric GTP binding proteins, G proteins, consist of three distinct subunits: alpha, beta, and gamma. There are 12 ... The beta and gamma subunits of G proteins are tightly bound under physiological conditions, and so far, seven beta and 11 gamma ... Using antibodies against the recombinant proteins for the alpha, beta, gamma1, and gamma2 subunits of the G protein complexes, ... Genomic characterization of the human heterotrimeric G protein alpha, beta, and gamma subunit genes.. Hurowitz EH, Melnyk JM, ...
  http://www.genes2cognition.org/db/Gene/G00001504
*  Immune response - CXCR4 signaling via second messenger Pathway Map - PrimePCR | Life Science | Bio-Rad
... beta/gamma. This causes the exchange of GDP for GTP bound to G protein alpha subunits and the dissociation of the beta/gamma ... G-alpha q11 activates phospholipase C beta (PLC-beta). PLC beta hydrolyses PI(4,5)P2 to generate two second messengers inositol ... The G-protein beta/gamma heterodimers activate PI3K gamma, recruiting noncatalytic p101 subunit and directly stimulating ... P3 is a second messenger that directly binds to PtdIns (3,4,5)P3-dependent protein kinase-1 (PDK1) and protein kinase B (AKT). ...
  http://www.bio-rad.com/en-us/prime-pcr-assays/pathway/immune-response-cxcr4-signaling-via-second-messenger
*  GTP binding and hydrolysis by the signal recognition particle during initiation of protein translocation. - Walter Lab
... a membrane protein composed of two subunits, SR alpha and SR beta, each of which also contains a GTP-binding domain. In the ... consists of one RNA and six protein subunits. The N-terminal domain of the 54K subunit contains a putative GTP-binding site, ... Here we show that the 54K subunit (M(r) 54,000) of SRP (SRP54) is a GTP-binding protein stabilized in a nucleotide-free state ... GTP binding and hydrolysis by the signal recognition particle during initiation of protein translocation.. Miller J, Wilhelm H ...
  http://walterlab.ucsf.edu/publication/454/gtp-binding-and-hydrolysis-by-the-signal-recognition-particle-during-initiation-of-protein-translocation/
*  KPNA6 Gene - GeneCards | IMA7 Protein | IMA7 Antibody
Protein Coding), Karyopherin Subunit Alpha 6, including: function, proteins, disorders, pathways, orthologs, and expression. ... a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in ... In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore ... Protein Symbol:. O60684-IMA7_HUMAN. Recommended name:. Importin subunit alpha-7 Protein Accession:. O60684. Secondary ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=KPNA6&keywords=GH01G033035&prefilter=genomic_location
*  RANBP5 (Human) Recombinant Protein (Q01) - (H00003843-Q01) - Products - Abnova
... recombinant protein with GST-tag at N-terminal. (H00003843-Q01) - Products - Abnova ... OTTHUMP00000040733,RAN binding protein 5,Ran_GTP binding protein 5,importin beta-3 subunit,karyopherin (importin) beta 3 ... a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in ... Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between ...
  http://www.abnova.com/products/products_detail.asp?catalog_id=H00003843-Q01
*  GNAQ - Wikipedia
... is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta (MIM ... Receptor activation catalyzes the exchange of GDP for GTP bound to the inactive G protein alpha subunit resulting in a ... Kabouridis PS, Waters ST, Escobar S, Stanners J, Tsoukas CD (1995). "Expression of GTP-binding protein alpha subunits in human ... Guanine nucleotide-binding protein G(q) subunit alpha is a protein that in humans is encoded by the GNAQ gene. Together with ...
  https://en.wikipedia.org/wiki/GNAQ
*  KPNB1 Gene - GeneCards | IMB1 Protein | IMB1 Antibody
Protein Coding), Karyopherin Subunit Beta 1, including: function, proteins, disorders, pathways, orthologs, and expression. ... Functions in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds ... In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore ... Functions in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds ...
  https://www.genecards.org/cgi-bin/carddisp.pl?id=6400&id_type=hgnc&search=6400
*  G-protein, beta subunit (IPR001632) | InterPro | EMBL-EBI
We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their ... InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites ... and to dissociate into active alpha subunit (GTP-bound) and beta/gamma dimer. The alpha subunit and the beta/gamma dimer go on ... The activated receptor promotes the exchange of bound GDP for GTP on the G protein alpha subunit. GTP binding changes the ...
  http://www.ebi.ac.uk/interpro/entry/IPR001632
*  IPO5 - Wikipedia
... a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in ... In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore ... Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between ... IPO5 facilitates cytoplasmic polyadenylation element-binding protein (CPEB)3 translocation by binding to RRM1 motif of CPEB3 in ...
  https://en.wikipedia.org/wiki/IPO5
*  KPNA6 - Wikipedia
... a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in ... In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore ... Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by ... Importin subunit alpha-7 is a protein that in humans is encoded by the KPNA6 gene. Nucleocytoplasmic transport, a signal- and ...
  https://en.wikipedia.org/wiki/KPNA6
*  KPNB1 - Wikipedia
... a heterodimer of importin alpha and beta subunits. Each of these subunits are part of the karyopherin family of proteins. ... Ran-GTP dissociates the karyopherin alphabeta heterodimer by displacing alpha from an overlapping binding site on beta". Proc. ... "Molecular interactions between the importin alpha/beta heterodimer and proteins involved in vertebrate nuclear protein import ... "Molecular interactions between the importin alpha/beta heterodimer and proteins involved in vertebrate nuclear protein import ...
  https://en.wikipedia.org/wiki/KPNB1
*  Gtp-binding protein alpha subunits, gi-go | Article about Gtp-binding protein alpha subunits, gi-go by The Free Dictionary
Find out information about Gtp-binding protein alpha subunits, gi-go. GTP-binding protein Explanation of Gtp-binding protein ... Looking for Gtp-binding protein alpha subunits, gi-go? ... Gtp-binding proteins. *GTP-binding regulatory protein beta-3 ... Gtp-binding protein alpha subunits, gi-go , Article about Gtp-binding protein alpha subunits, gi-go by The Free Dictionary ... G protein. (redirected from Gtp-binding protein alpha subunits, gi-go). Also found in: Medical. G protein. [′jē ‚prō‚tēn] (cell ...
  http://encyclopedia2.thefreedictionary.com/Gtp-binding+protein+alpha+subunits%2C+gi-go
*  EC 4.6.1.1 | definition of EC 4.6.1.1 by Medical dictionary
G proteins dissociate into GTP-bound alpha subunits-activating adenylyl cyclase, retinal phosphodiesterase, phospholipase C, ... and ion channels-and a complex of beta and gamma subunits, selectively activating certain forms of adenylate cyclase following ... Adenylate cyclase is intimately linked to the receptor-G protein machinery on the cytoplasmic face of cell membrane, which ... It is activated by the attachment of a hormone or neurotransmitter to a specific membrane-bound receptor. ...
  http://medical-dictionary.thefreedictionary.com/EC+4.6.1.1
*  Opioid receptor - Wikipedia
The gamma and beta sub-units are permanently bound together, producing a single Gβγ sub-unit. Heterotrimeric G proteins act as ... GTP) bind to. They are classified as heterotrimeric, meaning they contain three different sub-units, which include an alpha (α ... a GTP molecule binds to the free nucleotide-binding pocket, and the G protein becomes active. A Gα(GTP) complex is formed, ... The Gβγ sub-unit binds to the intracellular loop between the two trans-membrane helices of the VDCC. When the sub-unit binds to ...
  https://en.wikipedia.org/wiki/Opioid_receptor
*  Transcription - ChREBP regulation pathway Pathway Map - PrimePCR | Life Science | Bio-Rad
GDP-bound to the active GTP-bound form of G-protein alpha subunits and dissociation G-protein alpha from beta/gamma subunits. ... All of them are activated by activated G-alpha (s) subunits, whereas G-alpha (i) is capable to inhibite some forms Adenylyl ... regulation of carbohydrate-responsive element-binding protein by AMP-activated protein kinase. The Journal of biological ... Carbohydrate responsive element-binding protein (ChREBP): a key regulator of glucose metabolism and fat storage. Biochemical ...
  http://www.bio-rad.com/en-us/prime-pcr-assays/pathway/transcription-chrebp-regulation-pathway
*  How does cell know which ribosomes to target to the endoplasmic reticular membrane? | eNotes
GTP is Guanosine Triphosphate: a source of energy during protein synthesis. The SR beta has the same GTP binding capability, ... The SR is composed of two subunits: an alpha and a beta. The alpha faces the cytoplasm (outside of the ER) with an amino ... There at the alpha (SR alpha), there is a site for GTP binding. ... The SRP binds simultaneously with the ribosome, nascent protein ... Only then does the SRP recognize the N-terminal signal sequence of the protein; and the ribosome/nascent protein/SRP complex is ...
  https://www.enotes.com/homework-help/how-does-cell-know-which-ribosomes-target-123853
*  OriGene - RGS18 (NM 130782) cDNA Clone
Human regulator of G-protein signaling 18 (RGS18) available for purchase from OriGene - Your Gene Company. ... The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a ... This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers ... Gene Summary: This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, ...
  http://www.origene.com/human_cdna/NM_130782/SC321112.aspx
*  RCSB PDB - Protein Feature View - Potassium voltage-gated channel subfamily A member 2 - P16389 (KCNA2 HUMAN)
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex ... Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and ... GTP-bound form); this regulates channel activity by reducing location at the cell surface in response to CHRM1 activation (By ... Subunit Structure. Homotetramer and heterotetramer with other channel-forming alpha subunits, such as KCNA1, KCNA4, KCNA5, ...
  http://www.rcsb.org/pdb/protein/P16389
*  KCNA2 - Wikipedia
"Selective interaction of voltage-gated K+ channel beta-subunits with alpha-subunits". The Journal of Biological Chemistry. 271 ... Cachero TG, Morielli AD, Peralta EG (June 1998). "The small GTP-binding protein RhoA regulates a delayed rectifier potassium ... "Selective interaction of voltage-gated K+ channel beta-subunits with alpha-subunits". The Journal of Biological Chemistry. 271 ... Cachero TG, Morielli AD, Peralta EG (June 1998). "The small GTP-binding protein RhoA regulates a delayed rectifier potassium ...
  https://en.wikipedia.org/wiki/KCNA2
*  G alpha subunit - Wikipedia
... and to dissociate into active alpha subunit (GTP-bound) and beta/gamma dimer. The alpha subunit and the beta/gamma dimer go on ... The activated receptor promotes the exchange of bound GDP for GTP on the G protein alpha subunit. GTP binding changes the ... alpha; there are also fungal and plant classes of alpha subunits. The alpha subunit consists of two domains: a GTP-binding ... G proteins) are membrane-associated, heterotrimeric proteins composed of three subunits: alpha, beta, and gamma. G proteins and ...
  https://en.wikipedia.org/wiki/G_alpha_subunit
*  Regulator of G protein signaling - Wikipedia
The response is terminated upon GTP hydrolysis by the alpha subunit (InterPro: IPR001019), which can then re-bind the beta- ... with G protein beta subunits to form novel dimers that prevent G protein gamma subunit binding and G protein alpha subunit ... G protein gamma subunit-like) for binding G protein beta subunits (InterPro: IPR001770 Those RGS proteins that contain GGL ... RGS proteins markedly reduce the lifespan of GTP-bound alpha subunits by stabilising the G protein transition state. Whereas ...
  https://en.wikipedia.org/wiki/Regulator_of_G_protein_signaling
*  Apba1 - Amyloid-beta A4 precursor protein-binding family A member 1 - Mus musculus (Mouse) - Apba1 gene & protein
May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of AAP-beta (By similarity). ... Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle ... GTP-bound RAB6A. Also interacts with GTP-bound RAB6B (By similarity).By similarity ... Also part of the brain-specific heterotrimeric complex LIN-10/X11-alpha, LIN-2/CASK, and LIN7. Binds to the cytoplasmic domain ...
  https://www.uniprot.org/uniprot/B2RUJ5