*  Study of Azithromycin for Lymphocytic Bronchiolitis/Bronchitis After Lung Transplantation - Full Text View - ClinicalTrials.gov
chronic allograft rejection. bronchiolitis obliterans syndrome. Additional relevant MeSH terms: Bronchiolitis. Bronchitis. ... The role of the IL23/IL17 axis in bronchiolitis obliterans syndrome after lung transplantation. Am J Transplant. 2008 Sep;8(9): ... lymphocytic bronchitis or bronchiolitis. lung transplantation. acute allograft rejection. ... Azithromycin reduces airway neutrophilia and interleukin-8 in patients with bronchiolitis obliterans syndrome. Am J Respir Crit ...
  https://clinicaltrials.gov/ct2/show/NCT01109160?term=Bronchitis%3A+Clinical+Trials&rank=15
*  The impact of traffic air pollution on bronchiolitis obliterans syndrome and mortality after lung transplantation | Thorax
Pseudomonas aeruginosa colonization of the allograft after lung transplantation and the risk of bronchiolitis obliterans ... Circulating and intrapulmonary C-reactive protein: a predictor of bronchiolitis obliterans syndrome and pulmonary allograft ... Bronchiolitis obliterans syndrome 2001: an update of the diagnostic criteria. J Heart Lung Transplant 2002;21:297-310. ... The role of the IL23/IL17 axis in bronchiolitis obliterans syndrome after lung transplantation. Am J Transplant 2008;8:1911-20. ...
  http://thorax.bmj.com/content/early/2011/03/31/thx.2010.155192
*  Association between a Single Donor TARC/CCL17 Promotor Polymorphism and Obstructive Chronic Lung Allograft Dysfunction after...
AR, acute rejection; BOS, bronchiolitis obliterans syndrome; CF, cystic fibrosis; CLAD, chronic lung allograft dysfunction; ... bronchiolitis obliterans syndrome, BOS) and a restrictive form (restrictive allograft syndrome, RAS) (2). CLAD pathogenesis is ... Bronchiolitis obliterans syndrome 2001: an update of the diagnostic criteria. J Heart Lung Transplant (2002) 21(3):297-310.10. ... 4. Todd JL, Palmer SM.. Bronchiolitis obliterans syndrome: the final frontier for lung transplantation. Chest (2011) 140(2):502 ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC5592199/
*  Huber, Lars C<...
Therapy options for chronic lung allograft dysfunction-bronchiolitis obliterans syndrome following first-line immunosuppressive ... Development of allograft cancer after lung transplantation: a case report. Annals of thoracic and cardiovascular surgery : ... Plasma and bronchoalveolar lavage samples in acute lung allograft rejection: the potential role of cytokines as diagnostic ... Diagnostic value of plasma and bronchoalveolar lavage samples in acute lung allograft rejection: differential cytology. ...
  http://www.zora.uzh.ch/view/authors_for_linking_in_citation/Huber=3ALars_C=3A=3A.html
*  JCI - Welcome
... has addressed the importance of angiogenesis during fibro-obliteration of the allograft airway during bronchiolitis obliterans ... Bronchiolitis obliterans syndrome (BOS), a process of fibro-obliterative occlusion of the small airways in the transplanted ... Small airway fibrosis (bronchiolitis obliterans syndrome) is the primary obstacle to long-term survival following lung ... Role of CXCR2/CXCR2 ligands in vascular remodeling during bronchiolitis obliterans syndrome. ...
  https://www.jci.org/tags/40?content=articles&page=5
*  Lung Transplant - Cancer Therapy Advisor
a. Allograft dysfunction: Long term allograft dysfunction can lead to bronchiolitis obliterans and graft failure. Acute ... Veno-venous ECMO is an option to treat postoperative allograft dysfunction which delivers oxygenated blood to newly ... allograft dysfunction, related to acute rejection and/or ischemia-reperfusion injury, occurs in 10-25% of patients and causes ...
  https://www.cancertherapyadvisor.com/anesthesiology/lung-transplant/article/582469/
*  Search of: 'Bronchiolitis obliterans' - List Results - ClinicalTrials.gov
Immune Mechanisms of Rejection in Human Lung Allografts. *Bronchiolitis Obliterans. Observational. *Washington University ... Microparticles and Bronchiolitis Obliterans Syndrome. *Bronchiolitis Obliterans. *Other: Dosage of Microparticles (MPs) in ... L-CsA in the Prevention of Bronchiolitis Obliterans Syndrome (BOS) in Lung Transplant (LT) Patients. *Bronchiolitis Obliterans ... Long-term Safety Follow-up Study in the Prevention of Bronchiolitis Obliterans Syndrome (BOS). *Bronchiolitis Obliterans ...
  https://clinicaltrials.gov/ct2/results?cond=%22Bronchiolitis+obliterans%22&show_down=Y
*  The macrolide clarithromycin inhibits experimental posttransplant bronchiolitis obliterans - Zurich Open Repository and Archive
Chronic allograft dysfunction in form of bronchiolitis obliterans is the most important hurdle to improved longterm survival ... Chronic allograft dysfunction in form of bronchiolitis obliterans is the most important hurdle to improved longterm survival ... Recently, it was observed that the progression of bronchiolitis obliterans in lung transplant recipients might be inhibited by ... Recently, it was observed that the progression of bronchiolitis obliterans in lung transplant recipients might be inhibited by ...
  http://www.zora.uzh.ch/id/eprint/31367/
*  Effect of Continuous Positive Airway Pressure on Airway Inflammation and Oxidative Stress in Patients with Obstructive Sleep...
... acute lung allograft rejection, and posttransplant bronchiolitis obliterans) or history of other diseases associated with low ...
  https://www.hindawi.com/journals/crj/2016/3107324/
*  Clinical Trials sub-cluster 62
The long term survival of human lung allograft is hampered by the occurrence of chronic rejection, Bronchiolitis Obliterans ... Bronchiolitis obliterans (BrOb) is a well-recognized complication of allogeneic hematopoietic stem cell transplantation (HSCT ... BACKGROUND: Recent studies have shown strong evidence that bronchiolitis obliterans is the major long-term sequelae of exposure ... Soluble CD30 levels as a diagnostic marker for bronchiolitis obliterans syndrome following ... ...
  http://www.biomedsearch.com/cluster/19/Clinical-Trials/sub-62-p8.html
*  Profilaxis de la infección por aspergillus con anfotericina b nebulizada en pacientes trasplantados pulmonares
99m technetium-labeled AB distribution was uniform in 12 of 13 allografts without bronchiolitis obliterans syndrome (BOS) and ... PATIENTS AND METHODS: A study of risk factors was conducted in 55 consecutive lung allograft recipients. Twenty-three potential ... la distribución de nAB-99mTc fue uniforme en 12 de 13 injertos sin Síndrome de bronquiolitis obliterante (BOS) y en uno de 4 ... in 1 of 4 allografts with BOS. A close correlation was observed between regional drug distribution and regional perfusion (r= ...
  http://www.tdx.cat/handle/10803/4475
*  Physiology of chronic lung allograft dysfunction: back to the future? | European Respiratory Society
Late primary graft dysfunction after lung transplantation and bronchiolitis obliterans syndrome. Am J Transplant 2008; 8: 2454- ... The impact of traffic air pollution on bronchiolitis obliterans syndrome and mortality after lung transplantation. Thorax 2011 ... Restrictive allograft syndrome (ras): a novel form of chronic lung allograft dysfunction. J Heart Lung Transplant 2011; 30: 735 ... An international ISHLT/ATS/ERS clinical practice guideline: diagnosis and management of bronchiolitis obliterans syndrome. Eur ...
  http://erj.ersjournals.com/content/49/4/1700187
*  Immunologic Tolerance as Taught by Allografts | SpringerLink
2003). Correlation of bronchiolitis obliterans syndrome (BOS) with autoimmunity to collagen (V). Am. J. Transplantation 3, 152( ... 2000). Human allograft acceptance is associated with immune regulation. J. Clin. Invest. 106, 145.PubMedCrossRefGoogle Scholar ... 2001). Murine renal allografts: Spontaneous acceptance is associated with regulated t cell-mediated immunity. J. Immunol. 167, ... 2002). Nonhematopoietic allograft cells directly activate CD8+ T cells and trigger acute rejection: An alternative mechanism of ...
  https://link.springer.com/chapter/10.1007/978-1-4419-8999-4_21
*  Mark Nicolls | Stanford Medicine Profiles
Critical pathways leading to obliterative bronchiolitis in lung allografts CURRENT OPINION IN ORGAN TRANSPLANTATION Babu, A. N ... Bronchiolitis obliterans syndrome is a fibrotic occlusion of distal airways that is largely responsible for the morbidity and ... Small airway fibrosis (bronchiolitis obliterans syndrome) is the primary obstacle to long-term survival following lung ... also known as the bronchiolitis obliterans syndrome (BOS). BOS is the major obstacle to lung transplant success and affects up ...
  https://med.stanford.edu/profiles/mark-nicolls
*  The Role of Aspergillus in the Pathogenesis of Bronchiolitis Obliterans Syndrome - Stephen Weigt
Chronic lung allograft rejection, also known as bronchiolitis obliterans syndrome (BOS), is the most important factor limiting ... 2009) Aspergillus colonization of the lung allograft is a risk factor for bronchiolitis obliterans syndrome. Am J Transplant 9: ... The Role of Aspergillus in the Pathogenesis of Bronchiolitis Obliterans Syndrome Weigt, Stephen S. University of California Los ... The Role of Aspergillus in the Pathogenesis of Bronchiolitis Obliterans Syndrome. Weigt, Stephen S. / University of California ...
  http://grantome.com/grant/NIH/K23-HL094746-04
*  Innate Immune Regulation of Primary Graft Dysfunction - Howard Huang
2014) Hyaluronan contributes to bronchiolitis obliterans syndrome and stimulates lung allograft rejection through activation of ... Importantly, PGD is also a risk factor for developing Bronchiolitis Obliterans Syndrome, the main cause of late graft failure ... and has been associated with an increased risk for developing bronchiolitis obliterans syndrome and late graft failure. This ... 2015) Imaging mouse lung allograft rejection with (1)H MRI. Magn Reson Med 73:1970-8 ...
  http://grantome.com/grant/NIH/K08-HL107677-02
*  Acute Respiratory Failure Post Single Lung Transplantation: An Unusual Cause - Irish Medical Journal
... left sided hyper-expanded allograft and possible bronchiolitis obliterans in the allograft. ... The allograft failed to function optimally. The patient remained dyspnoeic on two litres of oxygen at discharge. CT ... Pulmonary vein stenosis with thrombus formation at the suture line or in the left atrium can mimic infection, allograft ... As little as 4-6 hours of warm ischaemia can cause irreversible allograft damage3. Embolization may result in cerebrovascular ...
  http://imj.ie/acute-respiratory-failure-post-single-lung-transplantation-an-unusual-cause/
*  Connective tissue growth factor antibodies - FibroGen, Inc.
... allograft rejection, chronic and acute transplant rejection (e.g., kidney, liver, or other organ); bronchiolitis obliterans, e. ...
  http://www.freepatentsonline.com/9034643.html
*  Effect of azithromycin on primary bronchial epithelial cells derived from stable lung allografts
1. Yates B, Murphy D M, Forrest I A. et al Azithromycin reverses airflow obstruction in established bronchiolitis obliterans ... Obliterative bronchiolitis (OB), the main cause of lung allograft failure, is characterised by airway inflammation, ... 8 in patients with bronchiolitis obliterans syndrome. Am J Respir Crit Care Med 2006. 174566-570.570 [PubMed] ... Effect of azithromycin on primary bronchial epithelial cells derived from stable lung allografts. Desmond M Murphy, Ian A ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2117319/
*  The attenuation of renal fibrosis by histone deacetylase inhibitors is associated with the plasticity of FOXP3+IL-17+ T cells |...
... blood Th17 cells and that the number of peripheral Tregs decreases after allografts in a mouse bronchiolitis obliterans model. ... Local IL-17 production and a decrease in peripheral blood regulatory T cells in an animal model of bronchiolitis obliterans. ... In one mouse bronchiolitis obliterans model, the interleukin (IL)-17 level has been shown to increase locally in the absence of ... may therefore play a role in post-transplantation allograft rejection. One UUO study has identified intra-renal dendritic cells ...
  https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-017-0630-6
*  Frank D'Ovidio, MD | Columbia University Department of Surgery
GASTRO-ESOPHAGEAL REFLUX AND ASPIRATION PROMOTES BRONCHIOLITIS OBLITERANS SYNDROME IMPAIRING LUNG ALLOGRAFT INNATE IMMUNITY. ... Development of bronchiolitis obliterans syndrome after lung transplantation is associated with bile acid aspiration. J Thorac ... Early development of bronchiolitis obliterans syndrome after lung transplantation is associated with bile acid aspiration. ... Effect of reflux and bile acid aspiration on lung allograft and its surfactant and innate immunity molecules SP-A and SP-D. Am ...
  http://dev.columbiasurgery.org/node/1304
*  Most recent papers with the keyword Hla antibodies | Read by QxMD
... also initiates the chronic alloimmune responses and airway-centred inflammation that predispose to bronchiolitis obliterans ... Allograft functioned well without rejection. She later received a pancreas allograft, again with a weakly positive FCXM, ... Similarly to HLA antibodies, recipients who have AT1R antibodies are at risk for allograft rejection and poor long-term graft ... Besides mediating allograft rejections via direct effects on endothelial and vascular smooth muscle without complement ...
  https://www.readbyqxmd.com/keyword/5934
*  Lung Transplantation (include selection, evaluation, process of organ acquisition, etc.) - ONA
CLAD was once thought to primarily manifest as bronchiolitis obliterans syndrome (BOS), a progressive and largely irreversible ... This restrictive phenotype has been termed restrictive chronic lung allograft dysfunction (rCLAD) or restrictive allograft ... and pneumonia re-emerge as a late complication in patients who develop bronchiolitis obliterans syndrome (BOS). ... Chronic lung allograft dysfunction (CLAD). This entity is thought to represent chronic alloimmune injury (chronic rejection) of ...
  https://www.oncologynurseadvisor.com/pulmonary-medicine/lung-transplantation-include-selection-evaluation-process-of-organ-acquisition-etc/article/625612/
*  Most recent papers with the keyword Lung transplantation | Read by QxMD
... therapy in lung transplant recipients with bronchiolitis obliterans syndrome (BOS) are not well established. MSCs were ... Chronic lung allograft dysfunction continues to be the main contributor to poor long-term allograft survival after lung ... Little is known about the pathogenetic mechanisms involved in restrictive chronic lung allograft dysfunction. In this study, we ... also initiates the chronic alloimmune responses and airway-centred inflammation that predispose to bronchiolitis obliterans ...
  https://www.readbyqxmd.com/keyword/3518