*  Iron response element - Wikipedia
"Fe2+ binds iron responsive element-RNA, selectively changing protein-binding affinities and regulating mRNA repression and ... For example, In high iron conditions in humans, IRP1 binds with an iron-sulphur complex [4Fe-4S] and adopts an aconitase ... "Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network". Annual Review ... For example, the mRNA of ferritin (an iron storage protein) contains one IRE in its 5' UTR. When iron concentration is low, ...
  https://en.wikipedia.org/wiki/Iron_response_element
*  Toluene dioxygenase - Wikipedia
Subramanian V, Liu TN, Yeh WK, Gibson DT (1979). "Toluene dioxygenase: purification of an iron-sulfur protein by affinity ...
  https://en.wikipedia.org/wiki/Toluene_dioxygenase
*  Molecular Mechanisms of Enzyme-Catalyzed Dioxygenation (An Interdisciplinary Review) | Springer for Research & Development
Purification of an Iron-Sulfur Protein by Affinity Chromatography. Biochem. Biophys. Commun. 91, 1131 (1979).Google Scholar ... Crutcher, S. E., and P. J. Geary: Properties of the Iron-Sulphur Proteins of the Benzene Dioxygenase System from Pseudomonas ... Sutin, N., and J. K. Yandell: Autoxidation Reactions Catalyzed by Iron (III) and Iron (IV) Dithiolate Complexes. J. Amer. Chem ... Hammond, G. S., and C.-H. S. Wu: Oxidation of Iron(II) Chloride in Nonaqueous Solvents. Adv. in Chem. 77, 186 (1968).Google ...
  https://rd.springer.com/chapter/10.1007/978-3-7091-8611-4_5
*  Design and Fine-tuning Redox Potentials of Metalloproteins Involved in Electron Transfer in Bioenergetics
... iron sulfur protein in the hydroquinone oxidation (Q(P)) site of the cytochrome bc1 complex. The 'proton-gated affinity change ... Meyer J. Iron-sulfur protein folds, iron-sulfur chemistry, and evolution. J Biol Inorg Chem. 2008;13:157-170. [PubMed] ... Design of FeS proteins. Iron-sulfur (FeS) containing proteins are the most versatile class of ET proteins in that they offer a ... De novo design of a non-natural fold for an iron-sulfur protein: alpha-helical coiled-coil with a four-iron four-sulfur cluster ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC4761536/
*  The identification of novel proteins involved in iron-sulphur cluster biogenesis in mycobacteria
Utilising this method, we were able to demonstrate affinity enrichment for Fe-S cluster assembly proteins, and Fe-S cluster- ... The identification of novel proteins involved in iron-sulphur cluster biogenesis in mycobacteria. Arries, Jesmine S. (2016-03) ... Iron-sulphur (Fe-S) clusters are ubiquitous cofactors that are required for the maturation of various proteins, many of which ... Soluble expression of the fusion protein was optimised and confirmed by immunodetection. We then employed affinity enrichment ...
  http://scholar.sun.ac.za/handle/10019.1/98341
*  Rieske protein - Wikipedia
... iron sulfur protein in the hydroquinone oxidation (Q(P)) site of the cytochrome bc1 complex. The 'proton-gated affinity change ... Rieske proteins are iron-sulfur protein (ISP) components of cytochrome bc1 complexes and cytochrome b6f complexes which were ... Iwata S, Saynovits M, Link TA, Michel H (May 1996). "Structure of a water soluble fragment of the 'Rieske' iron-sulfur protein ... Rieske iron-sulphur protein, C-terminal InterPro: IPR005805 Arsenite oxidase, small subunit InterPro: IPR014067 AIFM3; RFESD; ...
  https://en.wikipedia.org/wiki/Rieske_protein
*  The N-Terminal Domain of Human DNA Helicase Rtel1 Contains a Redox Active Iron-Sulfur Cluster
... expressed in Escherichia coli cells produces a protein that contains a redox active iron-sulfur cluster with the redox midpoint ... Purified RtelN retains a weak binding affinity for the single-stranded (ss) and double-stranded (ds) DNA in vitro. However, ... The N-Terminal Domain of Human DNA Helicase Rtel1 Contains a Redox Active Iron-Sulfur Cluster. Aaron P. Landry and Huangen Ding ... suggesting that the iron-sulfur cluster is not directly involved in the DNA interaction in the N-terminal domain of Rtel1. ...
  https://www.hindawi.com/journals/bmri/2014/285791/abs/
*  Biochimie
Mitochondrial iron-sulfur protein biogenesis and human disease Oliver Stehling , Claudia Wilbrecht , ... ... Why do antifreeze proteins require a solenoid? M. Banach , L. Konieczny , ... * Aptamer affinity ligands in protein ... Mitochondrial iron-sulfur protein biogenesis and human disease Oliver Stehling , Claudia Wilbrecht , ... ... Why do antifreeze proteins require a solenoid? M. Banach , L. Konieczny , ... * Aptamer affinity ligands in protein ...
  https://www.journals.elsevier.com/biochimie
*  Influence of Heme-Thiolate in Shaping the Catalytic Properties of a Bacterial Nitric-oxide Synthase
... and iron-sulfur proteins provided strong evidence that a relationship exists between changes in oxidation state of the iron ... affinity has been reported for Drosophila melanogaster iNOS (28). Binding affinities of BsNOS and W66H for imidazole were very ... Protein Expression and Purification Wild-type and mutant BsNOS proteins containing a His6 tag attached to their N termini were ... Determination of the redox potential of BsNOS wild-type, W66H, and W66F proteins. The fraction of oxidized protein at each ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC3234747/
*  Characterization of the metallo-cofactors of the tetrachloroethene reductive dehalogenase purified from Sulfurospirillum...
However, until now, only little is known about the role of the iron-sulfur clusters in the electron transfer within the enzyme ... In this study a mutant strain of S. multivorans producing an affinity-tagged PceA was characterized with regard to growth and ... The iron content and the number of corrinoids per molecule PceA were quantified. Using electron paramagnetic resonance ... which is a corrinoid-containing iron-sulfur protein [1]. This enzyme is located at the periplasmic face of the cytoplasmic ...
  https://infoscience.epfl.ch/record/186803
*  CDGSH iron sulfur domain - Wikipedia
The CDGSH iron sulfur domain 1 protein (also referred to as mitoNEET) is an integral membrane protein located in the outer ... also has been shown to bind mitoNEET with approximately equal affinity. Paddock ML, Wiley SE, Axelrod HL, Cohen AE, Roy M, ... The CDGSH iron sulfur domain are a group of iron-sulfur (Fe-S) clusters and a unique 39 amino acid CDGSH domain [C-X-C-X2-(S/T ... Iron in turn is essential for the function of several mitochondrial enzymes. The antidiabetic drug pioglitazone, in addition to ...
  https://en.wikipedia.org/wiki/CDGSH_iron_sulfur_domain
*  Cysteine - Wikipedia
Beyond the iron-sulfur proteins, many other metal cofactors in enzymes are bound to the thiolate substituent of cysteinyl ... The thiol group also has a high affinity for heavy metals, so that proteins containing cysteine, such as metallothionein, will ... Lill R, Mühlenhoff U (2006). "Iron-sulfur protein biogenesis in eukaryotes: components and mechanisms". Annu. Rev. Cell Dev. ... The sulfide in iron-sulfur clusters and in nitrogenase is extracted from cysteine, which is converted to alanine in the process ...
  https://en.wikipedia.org/wiki/Cysteine
*  Arabidopsis Glutaredoxin S17 and Its Partner, the Nuclear Factor Y Subunit C11/Negative Cofactor 2α, Contribute to Maintenance...
Certain GRXs are able to transfer iron-sulfur clusters to other proteins. To investigate the function of Arabidopsis ( ... Using affinity chromatography and split-Yellow Fluorescent Protein methods, a nuclear transcriptional regulator, the Nuclear ... However, a grxs17 knockout Arabidopsis mutant exhibited only a minor decrease in the activities of iron-sulfur enzymes, ... The sHSP22 Heat Shock Protein Requires the ABI1 Protein Phosphatase to Modulate Polar Auxin Transport and Downstream Responses ...
  http://www.plantphysiol.org/content/167/4/1643.short
*  Ghent University Academic Bibliography
The Arabidopsis iron-sulfur protein GRXS17 is a target of the ubiquitin E3 ligases RGLG3 and RGLG4 Astrid Nagels Durand, ... Isolation of protein complexes from the model legume Medicago truncatula by tandem affinity purification in hairy root cultures ... Glutaredoxin GRXS17 associates with the cytosolic iron-sulfur cluster assembly pathway Sabrina Iñigo, Astrid Nagels Durand, ... Transferring an optimized TAP-toolbox for the isolation of protein complexes to a portfolio of rice tissues Maarten Dedecker, ...
  https://biblio.ugent.be/publication?q=affiliation+exact+GE07&q=author+exact+801000840220
*  SDHB Antibody
Protein Aliases: Ip; Iron-sulfur subunit of complex II; mitochondrial; PGL4; SDH1; SDH2; SDHIP; succinate dehydrogenase [ ... 2 iron, 2 sulfur cluster binding. 3 iron, 4 sulfur cluster binding. 4 iron, 4 sulfur cluster binding. oxidoreductase activity. ... Antigen affinity chromatography Storage buffer. PBS, pH 7, with 40% glycerol Contains. 0.01% thimerosal ... iron sulfur (Ip); succinate dehydrogenase complex, subunit B, iron sulfur (Ip) Gene Aliases: 0710008N11Rik; CWS2; IP; PGL4; SDH ...
  https://www.thermofisher.com/antibody/product/SDHB-Antibody-Polyclonal/PA5-21587
*  Electron Carrier Molecules | On the Shoulders of Giants
In general cytochrome proteins and their heme groups have a higher affinity for electrons than Iron Sulfur groups. Thus, ... cytochrome carriers tend to be used at the end of the chain, and Iron sulfur at the beginning. ... In the above picture, iron is in orange, nitrogen in blue, carbon in green and oxygen in red. While the structure pictured is ... The cytochrome bc complex is made up of multiple proteins, many of which have their own prosthetic groups. Several of these ...
  https://giantshoulders.wordpress.com/2007/10/29/electron-carrier-molecules/
*  The NMR contribution to protein-protein networking in Fe-S protein maturation, JBIC Journal of Biological Inorganic Chemistry |...
"The NMR contribution to protein-protein networking in Fe-S protein maturation, JBIC Journal of Biological Inorganic Chemistry" ... This sug- tein targets [169, 170]. The origin of iron and sulfur ions gests that cluster-binding affinity is lower once the ... The NMR contribution to protein-protein networking in Fe-S protein maturation. The NMR contribution to protein-protein ... Iron-sulfur proteins were among the first class of metalloproteins that were actively studied using NMR spectroscopy tai- ...
  https://www.deepdyve.com/lp/springer_journal/the-nmr-contribution-to-protein-protein-networking-in-fe-s-protein-vcnU0qiKUk
*  Cysteine - Wikipedia
Beyond the iron-sulfur proteins, many other metal cofactors in enzymes are bound to the thiolate substituent of cysteinyl ... iron in cytochrome P450 and nickel in the [NiFe]-hydrogenases.[16] The sulfhydryl group also has a high affinity for heavy ... Precursor to iron-sulfur clusters[edit]. Cysteine is an important source of sulfide in human metabolism. The sulfide in iron- ... "Iron-sulfur protein biogenesis in eukaryotes: components and mechanisms". Annu. Rev. Cell Dev. Biol. 22: 457-86. doi:10.1146/ ...
  https://en.wikipedia.org/wiki/L-cysteine
*  3s5e - Proteopedia, life in 3D
FRDA_HUMAN] Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins ... The binding affinities follow the trend Fxn ~ I154F , W155F , W155A ~ W155R. The Fxn variants also have diminished ability to ... Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type ... Cavadini P, O'Neill HA, Benada O, Isaya G. Assembly and iron-binding properties of human frataxin, the protein deficient in ...
  http://proteopedia.org/wiki/index.php/3s5e
*  Protocols and Video Articles Authored by Janet Smith
The motion of the Rieske iron-sulfur protein extrinsic domain, essential for electron transfer, must also be different in the ... The relative affinities of the two PurBoxes differ significantly, such that upstream PurBox1 (-81 to -68 relative to the ... Indeed, two ASRA proteins, CXCR6 and BTG2, and two other related self-renewal pattern associated (SRPA) proteins identified in ... Soluble truncated proteins were subjected to crystallization trials in a 96-well format, and two of these proteins were ...
  https://www.jove.com/author/Janet_Smith
*  Cold Rice and Bean Salad
... and iron-sulphur-containing prosthetic groups, it could take the place of ferrous iron in some mononuclear metalloenzymes. ... while Dps is an iron-binding protein that can protect DNA from oxidative damage (Park et al., 2005). Thus, it appears that ... Many bacteria possess a high-affinity ABC cassette transporter for manganese and, at least in Gram-positive bacteria, ... Look up 'heme iron diabetes'. If you eat a lot of meat you need more of the minerals which prevent iron-dependent damage. ...
  https://freetheanimal.com/2014/09/rice-bean-salad.html
*  Iron - Wikipedia
4H+ outside Although the heme proteins are the most important class of iron-containing proteins, the iron-sulfur proteins are ... of all the protein chains that leads to the other subunits of hemoglobin changing shape to a form with larger oxygen affinity. ... Another important class of iron-sulfur proteins is the ferredoxins, which have multiple iron atoms. Transferrin does not belong ... Mild iron deficiency can be prevented or corrected by eating iron-rich foods and by cooking in an iron skillet. Because iron is ...
  https://en.wikipedia.org/wiki/Iron
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... and help assemble iron-sulfur clusters in proteins. Mitochondria also have an essential role in heat production. Mutations of ... the biotinylatable protein sequence has been incorporated into many target proteins because of the high affinity interaction ... Biochemistry, Issue 82, amyloid, soluble protein oligomer, amyloid precursor, protein misfolding, amyloid fibril, protein ... or protein domain (e.g., protein-protein interaction, folding). This method has been optimized in several laboratories and ...
  https://www.jove.com/visualize/abstract/23144833/population-genetic-structure-origins-native-hawaiians-multiethnic
*  NDUFS8 Antibody
... iron-sulfur protein 8; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; NADH-ubiquinone oxidoreductase 23 ... Antigen affinity chromatography Storage buffer. 0.1M tris glycine, pH 7, with 20% glycerol ... 4 iron, 4 sulfur cluster binding. molecular_function. oxidoreductase activity. oxidoreductase activity, acting on NAD(P)H. iron ... Protein Aliases: CI-23k; CI-23kD; CI23KD; complex I 23kDa subunit; Complex I-23kD; mitochondrial; NADH dehydrogenase ( ...
  https://www.thermofisher.com/antibody/product/NDUFS8-antibody-Polyclonal/PA5-22327
*  The defective splicing caused by the ISCU intron mutation in patients with myopathy with lactic acidosis is repressed by PTBP1...
All affected proteins contain iron-sulfur (Fe-S) clusters, which led to the suggestion that the disease was caused by ... IGF2BP1 was the only factor that showed higher affinity to the mutant sequence making it a possible key factor in the incorrect ... ISCU functions as a scaffold protein in the assembly of iron-sulphur (Fe-S) clusters important for electron transport in Kreb's ... dependent pain insensitivity and Iron-Sulphur cluster assembly protein U (ISCU) myopathy. ...
  http://umu.diva-portal.org/smash/record.jsf?pid=diva2:471191