*  Disopyramide - Wikipedia
Disopyramide also has an anticholinergic effect on the heart which accounts for many adverse side effects. Disopyramide is ... to every patient begun on disopyramide. This combination increases acceptance of higher disopyramide dosing, important since ... Another concern about disopyramide has been the hypothetical potential for inducing sudden death from its type 1 anti- ... These concerns about the drug must be viewed from the clinical perspective that disopyramide is generally the last agent that ...
  https://en.wikipedia.org/wiki/Disopyramide
*  Torsades de pointes - Wikipedia
"FDA Drug Safety Communication: Revised recommendations for Celexa (citalopram hydrobromide) related to a potential risk of ... In addition, inherited long QT syndrome significantly increases the risk of episodes of TdP. Knowledge that TdP may occur in ... If this does not occur, however, possible adverse outcomes include palpitations, dizziness, lightheadedness (during shorter ... disopyramide, sotalol, amiodarone, amitriptyline, chlorpromazine, erythromycin) and/or congenital syndromes (LQT1-LQT4 gene ...
  https://en.wikipedia.org/wiki/Torsades_de_pointes
*  Tenoretic (Atenolol and Chlorthalidone): Side Effects, Interactions, Warning, Dosage & Uses
... drug interactions, warnings, patient labeling, reviews, and related medications. ... Potential Adverse Effects. In addition, a variety of adverse effects not observed in clinical trials with atenolol but reported ... Disopyramide is a Type I antiarrhythmic drug with potent negative inotropic and chronotropic effects. ... Consistent with its negative chronotropic effect due to beta blockade of the SA node, atenolol increases sinus cycle lengthand ...
  https://www.rxlist.com/tenoretic-drug.htm
*  Tofranil (Imipramine): Side Effects, Interactions, Warning, Dosage & Uses
... drug interactions, warnings, patient labeling, reviews, and related medications. ... especially during the initial few months of a course of drug therapy, or at times of dose changes, either increases or ... Note - Although the listing which follows includes a few adverse reactions which have not been reported with this specific drug ... the drug is essentially free from teratogenic potential. In the three species studied, only one instance of fetal abnormality ...
  https://www.rxlist.com/tofranil-drug.htm
*  Drug Summary
... dosing and administering information to help phsyicans more efficiently and accurately prescribe in their practice PDR's drug ... PDR Drug Summaries are concise point-of-care prescribing, ... thereby increasing the potential for adverse effects (i.e., ... Danazol increases circulating levels of C1 INH and therby increases C4 of the complement system, which also is deficient in ... Disopyramide: (Moderate) Danazol is a CYP3A4 inhibitor and can decrease the hepatic metabolism of disopyramide. Patients ...
  http://www.pdr.net/drug-summary/Danazol-danazol-1265
*  Cordarone IV (Amiodarone Intravenous): Side Effects, Interactions, Warning, Dosage & Uses
... drug interactions, warnings, patient labeling, reviews, and related medications. ... Disopyramide increases QT prolongation which could cause arrhythmia. Fluoroquinolones, macrolide antibiotics, and azoles are ... Hypotension is the most common adverse effect seen with Cordarone I.V. In clinical trials, treatment-emergent, drug-related ... In view of the long and variable half-life of amiodarone, potential for drug interactions exists not only with concomitant ...
  https://www.rxlist.com/cordarone-iv-drug.htm
*  Management of Grapefruit-Drug Interactions - American Family Physician
There are equally effective alternatives to these drug classes that do not have the potential to interact with grapefruit. ... However, the fruit has been shown to affect the metabolism of many medications, increasing the risk of toxicity and adverse ... These alternative drugs may be substituted if a patient experiences or is at risk of a grapefruit-drug interaction. Patients ... small increases in plasma concentration may cause drastic increases in therapeutic or adverse effects.9 ...
  https://www.aafp.org/afp/2006/0815/p605.html
*  Grapefruit-drug interactions - Wikipedia
... disopyramide (Norpace), propafenone (Rythmol) and carvedilol (Coreg) Amlodipine: Grapefruit increases the available amount of ... Bressler R (November 2006). "Grapefruit juice and drug interactions. Exploring mechanisms of this interaction and potential ... Some fruit juices and fruits can interact with numerous drugs, in many cases causing adverse effects. The effect was first ... A decrease in drug metabolism means more of the original form of the drug could pass unchanged to systemic blood circulation.[ ...
  https://en.wikipedia.org/wiki/Grapefruit%E2%80%93drug_interactions
*  Sentravil PM-25 - FDA prescribing information, side effects and uses
Includes: indications, dosage, adverse reactions, pharmacology and more. ... Because of the potential for serious adverse reactions in nursing infants from amitriptyline, a decision should be made whether ... especially during the initial few months of a course of drug therapy, or at times of dose changes, either increases or ... Type 1 A and 1 C antiarrhythmics are generally contraindicated (e.g., quinidine, disopyramide, and procainamide).. In rare ...
  https://www.drugs.com/pro/sentravil-pm-25.html
*  Drug Summary
... dosing and administering information to help phsyicans more efficiently and accurately prescribe in their practice PDR's drug ... PDR Drug Summaries are concise point-of-care prescribing, ... Monitor for potential adverse effects of bosentan during ... exceeding the recommended daily dose of 40 mg/day increases drug exposure which may increase the risk of elevated hepatic ... Disopyramide: (Moderate) Zafirlukast is a CYP3A4 inhibitor which theoretically may decrease the hepatic metabolism of ...
  http://www.pdr.net/drug-summary/Accolate-zafirlukast-2054
*  PPT - Pharmacology Part 2 for Medical Students and Nurse PowerPoint presentation | free to download - id: 7ec142-NzU2N
This slower release system increases the duration of action. 133. Adverse Effects of Estrogens*Nausea and vomiting (most common ... Action Potential 11. CLASS (1A) antiarrhythmic*Quinidine *Procainamide *Disopyramide. 12. Quinidine*Prototype class 1A , bind ... 8-12 hours after drug is administered *The drug is 99 plasma bound, therefore it does not diffuse into CSF, urine, or breast ... important adverse effects of statins are elevations of the serum transaminase levels and development of myositis. These adverse ...
  http://www.powershow.com/view0/7ec142-NzU2N/Pharmacology_Part_2_for_Medical_Students_and_Nurse_powerpoint_ppt_presentation
*  Apidra (Insulin Glulisine [rDNA origin] Inj): Side Effects, Interactions, Warning, Dosage & Uses
... drug interactions, warnings, patient labeling, reviews, and related medications. ... Hypoglycemia is the most common adverse reaction of insulin therapy, including APIDRA. The risk of hypoglycemia increases with ... this drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is ... disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, propoxyphene, pentoxifylline, salicylates, somatostatin ...
  https://www.rxlist.com/apidra-drug.htm
*  Dilantin-125 (phenytoin) dose, indications, adverse effects, interactions... from PDR.net
... dosing and administering information to help phsyicans more efficiently and accurately prescribe in their practice PDR's drug ... PDR Drug Summaries are concise point-of-care prescribing, ... In addition, disopyramide doses may need to be reduced if a ... The dose of the concomitant drug may need to be adjusted. Boceprevir: (Severe) The potential for boceprevir treatment failure ... Phenytoin dosage increases of 20 to 100% have been required in some patients, depending on the chemotherapy administered. ...
  http://www.pdr.net/drug-summary/dilantin-125?druglabelid=1843
*  LUCRIN SR DCS 3.75 MG POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLE | Drugs.com
including the potential for Torsade de pointes prior to initiating LUCRIN SR.. Reporting of suspected adverse reactions. ... pregnant during treatment, the drug must be discontinued. The patient must be apprised of this evidence and. the potential for ... Transient increases in acid phosphatase levels sometimes occur early in the treatment period but usually. return to normal or ... such as class IA (e.g. quinidine, disopyramide) or class III (e.g. amiodarone, sotalol, dofetilide, ibutilide). antiarrhythmic ...
  https://www.drugs.com/uk/lucrin-sr-dcs-3-75-mg-powder-and-solvent-for-prolonged-release-suspension-for-injection-in-pre-fille-leaflet.html
*  DailyMed - AMITRIPTYLINE HYDROCHLORIDE- amitriptyline hydrochloride tablet, film coated
Because of the potential for serious adverse reactions in nursing infants from amitriptyline, a decision should be made whether ... especially during the initial few months of a course of drug therapy, or at times of dose changes, either increases or ... Type 1 A and 1 C antiarrhythmics are generally contraindicated (e.g., quinidine, disopyramide, and procainamide). ... ADVERSE REACTIONS Within each category the following adverse reactions are listed in order of decreasing severity. Included in ...
  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=705a2bae-031d-4218-82fe-4346542c0baa
*  Quinidine Gluconate Injection (quinidine gluconate) dose, indications, adverse effects, interactions... from PDR.net
... dosing and administering information to help phsyicans more efficiently and accurately prescribe in their practice PDR's drug ... PDR Drug Summaries are concise point-of-care prescribing, ... concurrent use increases the potential for serious and/or life- ... Because of their potential to prolong refractoriness, Class IA antiarrhythmics (e.g., disopyramide, quinidine, and procainamide ... The potential for increased pharmacologic effects of amantadine, including adverse events such as dizziness, altered mental ...
  http://www.pdr.net/drug-summary/Quinidine-Gluconate-Injection-quinidine-gluconate-981
*  Tambocor - FDA prescribing information, side effects and uses
Includes: indications, dosage, adverse reactions, pharmacology and more. ... No adverse drug interactions were apparent. However, no formal studies have been performed to demonstrate the usefulness of ... Small increases in plasma digoxin levels are seen during coadministration of Tambocor with digoxin. Small increases in both ... Tambocor should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. ...
  https://www.drugs.com/pro/tambocor.html
*  Isradipine (Oral Route) Side Effects - Mayo Clinic
Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. ... Drug Interactions Although certain medicines should not be used together at all, in other cases two different medicines may be ... Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been ... As a result, isradipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its ...
  https://www.mayoclinic.org/drugs-supplements/isradipine-oral-route/side-effects/drg-20071647?p=1
*  Patente US20080125843 - Combined parasympathetic stimulation and drug therapy - Google Patentes
... disopyramide, dofetilide, flecainide, procainamide, propafenone, quinidine, and sotalol. Potential adverse effects of these ... If the detection indicates physical exertion, the neurostimulator rate increases the patient's heart rate above the normal ... The drug administered typically includes either: * *a sinus rhythm maintenance drug (i.e., an antiarrhythmic drug), such as a ... The drug administered typically includes a sinus rhythm maintenance drug (i.e., an antiarrhythmic drug) or a ventricular rate ...
  http://www.google.es/patents/US20080125843
*  Genvoya - FDA prescribing information, side effects and uses
Includes: indications, dosage, adverse reactions, pharmacology and more. ... Adverse Reactions. The following adverse drug reactions are discussed in other sections of the labeling:. *Severe Acute ... Complete information regarding potential drug-drug interactions with other antiretroviral medications is not provided [see ... No drug-related increases in tumor incidence were found in rats at doses up to 2000 mg per kg per day at exposures 12- to 27 ...
  https://www.drugs.com/pro/genvoya.html
*  Stribild - FDA prescribing information, side effects and uses
Includes: indications, dosage, adverse reactions, pharmacology and more. ... Complete information regarding potential drug-drug interactions with other antiretroviral medications is not provided [see ... No drug-related increases in tumor incidence were found in rats at doses up to 2000 mg per kg per day at exposures 12- to 27- ... Risk of Adverse Reactions or Loss of Virologic Response Due to Drug Interactions. The concomitant use of Stribild and other ...
  https://www.drugs.com/pro/stribild.html
*  Hypertrophic cardiomyopathy - Wikipedia
There are several potential challenges associated with routine screening for HCM in the United States. First, the U.S. athlete ... The result of this is that the left ventricular pressure increases and the ascending aortic pressure decreases, with an ... For people whose symptoms are not relieved by the above treatments, disopyramide can be considered for further symptom relief. ... People who continue to have symptoms despite drug therapy can consider more invasive therapies. Intravenous phenylephrine (or ...
  https://en.wikipedia.org/wiki/Hypertrophic_cardiomyopathy
*  Atrial Fibrillation/Atrial flutter: Pharmacologic and Catheter Ablation to Maintain Sinus Rhythm - The Clinical Advisor
It has a low potential for proarrhythmia. This drug increases mortality in patients with advanced heart failure and should not ... Since amiodarone treatment may be associated with serious and frequent adverse effects, especially during long-term treatment, ... The drugs more frequently used or studied include sodium channel blockers (disopyramide, quinidine, flecainide, propafenone), ... New antiarrhythmic drug strategies include more atrial selective agents, drugs similar to amiodarone but with a less toxic ...
  https://www.clinicaladvisor.com/cardiology/atrial-fibrillationatrial-flutter-pharmacologic-and-catheter-ablation-to-maintain-sinus-rhythm/article/583128/
*  Eryc - FDA prescribing information, side effects and uses
Includes: indications, dosage, adverse reactions, pharmacology and more. ... but the passage of the drug across the blood-brain barrier increases in meningitis. The drug is excreted in human milk. The ... Adverse Reactions. The most frequent side effects of oral erythromycin preparations are gastrointestinal and are dose-related. ... disopyramide, lovastatin, bromocriptine, valproate, terfenadine and astemizole. Serum concentrations of drugs metabolized by ...
  https://www.drugs.com/pro/eryc.html