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*  Patent US5112804 - Pharmaceutical composition and method of intranasal administration - Google Patents
A composition and method for nasal administration of pharmaceuticals utilizes glycyrrhetinic acid as an absorption enhancer. ... The intranasal administration of vitamin B-12 is illustrated as follows.. 1 ml of a vitamin B-12 solution containing 1,000μg/ml ... The intranasal administration of human ACTH is illustrated as follows.. A 0.5% (w/v) 18β-glycyrrhetinic acid vehicle solution ... Pharmaceutical preparations for intranasal administration. US5989582 *. 14 Feb 1996. 23 Nov 1999. Weg; Stuart L.. ...
  http://www.google.com.au/patents/US5112804
*  Cell-Penetrating Peptide-Modified Block Copolymer Micelles Promote Direct Brain Delivery via Intranasal Administration |...
We evaluated the brain distribution of coumarin, acting as a model chemical, after intravenous or intranasal administration of ... The amount of coumarin in the brain after intranasal administration was significantly higher than that after intravenous ... Finally, we determined the brain distribution and biodistribution after intranasal administration of coumarin-loaded MPEG-PCL- ... Cell-Penetrating Peptide-Modified Block Copolymer Micelles Promote Direct Brain Delivery via Intranasal Administration. ...
  https://link.springer.com/article/10.1007%2Fs11095-011-0440-7
*  Intragastric and Intranasal Administration of Lactobacillus paracasei NCC2461 Modulates Allergic Airway Inflammation in Mice
... ... We aimed at testing the immunomodulatory effects of intranasal versus intragastric administration of Lactobacillus paracasei ... A concerted selection of intervention schedule, doses, and administration routes (intranasal versus intragastric) may markedly ... Intranasal L. paracasei NCC2461 efficiently protected sensitized mice upon exposure to OVA aerosols in a dose-dependent manner ...
  https://www.hindawi.com/journals/iji/2012/686739/abs/
*  Molecules | Free Full-Text | Identification of Absorbed Constituents in the Rabbit Plasma and Cerebrospinal Fluid after...
... after intranasal administration of Asari Radix et Rhizoma (AR). In total, 47 absorbed AR constituents including 14 monoterpenes ... and comprehensively analyze the absorbed constituents after intranasal administration of TCM. These findings extend our ... Keywords: nasal therapy; Asarum heterotropoides var. mandshuricum; intranasal administration; effective substance; ... Identification of Absorbed Constituents in the Rabbit Plasma and Cerebrospinal Fluid after Intranasal Administration of Asari ...
  http://www.mdpi.com/1420-3049/19/4/4857
*  Efficacy and Safety Study of Intranasal Administration of 100, 200, and 400 μg of Fluticasone Propionate - Full Text View -...
Must be able to cease treatment with intranasal medications including, but not limited to, intranasal steroids, intranasal ... Efficacy and Safety Study of Intranasal Administration of 100, 200, and 400 μg of Fluticasone Propionate. The safety and ... The primary objective of this study is to compare the efficacy of intranasal administration of 100, 200, and 400 μg of ... Multicenter Study Evaluating the Efficacy and Safety of Intranasal Administration of 100, 200, and 400 μg of Fluticasone ...
  https://clinicaltrials.gov/ct2/show/NCT01624662?term=optinose&rank=4
*  Viruses | Free Full-Text | Intranasal Administration of Maleic Anhydride-Modified Human Serum Albumin for Pre-Exposure...
Intranasal administration of ML-HSA before RSV infection resulted in significant decrease of the viral titers in the lungs of ... ML-HSA shows promise for further development into an effective, safe, affordable, and easy-to-use intranasal regimen for pre- ... Sun Z, Wang Q, Jia R, Xia S, Li Y, Liu Q, Xu W, Xu J, Du L, Lu L, Jiang S. Intranasal Administration of Maleic Anhydride- ... Intranasal administration of ML-HSA before RSV infection resulted in significant decrease of the viral titers in the lungs of ...
  http://www.mdpi.com/1999-4915/7/2/798
*  Study Evaluating the Safety of Intranasal Administration of 400 μg of Fluticasone Propionate Twice a Day (BID) Using a Novel Bi...
Study Evaluating the Safety of Intranasal Administration of 400 μg of Fluticasone Propionate Twice a Day (BID) Using a Novel Bi ... This is an open-label, multicenter study designed to assess the safety of intranasal administration of 400 μg of fluticasone ... A 3-Month Open-Label Multicenter Study Evaluating the Safety of Intranasal Administration of 400 μg of Fluticasone Propionate ... Must be able to cease treatment with intranasal steroids and inhaled corticosteroids (except permitted doses listed above for ...
  https://clinicaltrials.gov/ct2/show/NCT01623323?recr=Open&cond=%22Sinusitis%22&rank=12
*  Activity-Dependent Neurotrophic Factor: Intranasal Administration of Femtomolar-Acting Peptides Improve Performance in a Water...
Activity-Dependent Neurotrophic Factor: Intranasal Administration of Femtomolar-Acting Peptides Improve Performance in a Water ... Activity-Dependent Neurotrophic Factor: Intranasal Administration of Femtomolar-Acting Peptides Improve Performance in a Water ... Activity-Dependent Neurotrophic Factor: Intranasal Administration of Femtomolar-Acting Peptides Improve Performance in a Water ... Activity-Dependent Neurotrophic Factor: Intranasal Administration of Femtomolar-Acting Peptides Improve Performance in a Water ...
  http://jpet.aspetjournals.org/content/293/3/1091/tab-e-letters
*  GMS | 65th Annual Meeting of the German Society of Neurosurgery (DGNC) | Intranasal administration of neural stem cell-mediated...
Intranasal administration of neural stem cell-mediated enzym/prodrug therapy using a novel HSV-thymidine kinase variant ... Those receiving additional intranasal administration of NSC-TK007 displayed a significant tumor growth inhibition of 81% versus ... Here, we demonstrate that the non-invasive intranasal administration of tumor-targeting NSC is able to deliver a novel suicide ... Therapeutic effects of intratumoral (3x105 cells) and intranasal (1.5x106) NSC-TK007 application alone and the sequential ...
  http://www.egms.de/static/en/meetings/dgnc2014/14dgnc280.shtml
*  Molecular Mechanisms of Induction of Antigen-Specific Allograft Tolerance by Intranasal Peptide Administration | The Journal of...
We have previously shown that intranasal (i.n.) administration of a single MHC class II-restricted HY peptide to female mice ... Molecular Mechanisms of Induction of Antigen-Specific Allograft Tolerance by Intranasal Peptide Administration. Katy Derbyshire ... Molecular Mechanisms of Induction of Antigen-Specific Allograft Tolerance by Intranasal Peptide Administration ... Molecular Mechanisms of Induction of Antigen-Specific Allograft Tolerance by Intranasal Peptide Administration ...
  http://www.jimmunol.org/content/early/2011/04/12/jimmunol.1002444
*  A Study of Diazepam After Intranasal and Intravenous Administration to Healthy Volunteers - Tabular View - ClinicalTrials.gov
A Study of Diazepam After Intranasal and Intravenous Administration to Healthy Volunteers. This study has been completed. ... A Study of Diazepam After Intranasal and Intravenous Administration to Healthy Volunteers. ... It was approved by the Food and Drug Administration (FDA) for use in the United States and is currently sold as Valium® tablets ... Positive serum pregnancy test at Screening or urine pregnancy test prior to each administration of study drug for all women, ...
  https://clinicaltrials.gov/ct2/show/record/NCT01364558
*  Intranasal administration of acetylcholinesterase inhibitors | BMC Neuroscience | Full Text
Intranasal drug delivery is an effective option for the treatment of Alzheimer's disease and other central nervous system ... and opportunities for intranasal acetylcholinesterases, in particular galantamine. An in vitro screening model facilitated the ... Liu XF, Fawcett JR, Throne RG, DeFor TA, Frey WH: Intranasal administration of insulin-like growth factor-I bypasses the blood- ... Wang D, Gao Y, Yun L: Study on brain targeting of raltitrexed following intranasal administration in rats. Cancer Chemother ...
  https://0-bmcneurosci-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/1471-2202-9-S3-S6
*  Preferential Brain Homing following Intranasal Administration of Trypanosoma cruzi▿ - CORE
Preferential Brain Homing following Intranasal Administration of Trypanosoma cruzi▿ By Kacey Caradonna and Mercio PereiraPerrin ...
  https://core.ac.uk/display/8274082
*  Intranasal Injection Versus Topical Administration of Epinephrin During Endoscopic Sinus Surgery - Full Text View -...
Drug: Epinephrin (Intranasal injection) Drug: Epinephrin (Topical administration) Hide Detailed Description Detailed ... Intranasal Injection Versus Topical Administration of Epinephrin During Endoscopic Sinus Surgery. The safety and scientific ... Active Comparator: Topical administration An an intranasal injection of saline will be used as control, and thereafter cotton ... Drug: Epinephrin (Topical administration) An intranasal injection of saline solution, followed by placement of cotton pledgets ...
  https://clinicaltrials.gov/ct2/show/study/NCT01075581?show_desc=Y
*  Intranasal Injection Versus Topical Administration of Epinephrin During Endoscopic Sinus Surgery - Full Text View -...
Intranasal Injection Versus Topical Administration of Epinephrin During Endoscopic Sinus Surgery. The safety and scientific ... Active Comparator: Topical administration An an intranasal injection of saline will be used as control, and thereafter cotton ... Drug: Epinephrin (Topical administration) An intranasal injection of saline solution, followed by placement of cotton pledgets ... We hypothesize that topical administration of epinephrine provides a hemostatic effect not inferior to that of intranasal ...
  https://clinicaltrials.gov/ct2/show/NCT01075581?recr=Open&cond=%22Bradycardia%22&rank=16
*  Intranasal administration of RSV antigen-expressing MCMV elicits robust tissue-resident effector and effector memory CD8+ T...
Intranasal administration of RSV antigen-expressing MCMV elicits robust tissue-resident effector and effector memory CD8+ T ... 2016) Intranasal administration of RSV antigen-expressing MCMV elicits robust tissue-resident effector and effector memory CD8+ ... We found that intranasal vaccination generated robust and durable tissue-resident effector and effector memory CD8+ T cell ... The generation of these antigen-experienced cells by intranasal vaccination resulted in earlier T cell responses, interferon ...
  http://researchrepository.murdoch.edu.au/id/eprint/34844/
*  Effect of intranasal administration of norethisterone and progesterone on pituitary and gonadal function in adult male and...
Effect of intranasal administration of norethisterone and progesterone on pituitary and gonadal function in adult male and ... Effect of intranasal administration of norethisterone and progesterone on pituitary and gonadal function in adult male and ... Intranasal spray of NET in adult cycling female monkeys between days 5 and 14 shortened the menstrual cycle ascribed to a ... The effect of intranasal spray of norethisterone (NET) [68-22-4] and progesterone (P) [57-83-0] on serum testosterone (T) [58- ...
  http://eprints.iisc.ernet.in/14701/
*  Pharmacoimaging of Blood-Brain Barrier Permeable (FDG) and Impermeable (FLT) Substrates After Intranasal (IN) Administration |...
Figure S1 Cine of 3-dimensional reconstruction of dynamic PET data after [18F]FLT intranasal administration co-registered with ... Figure S2 Cine of 3-dimensional reconstruction of dynamic PET data after [18F]FLT intranasal administration co-registered with ... Pharmacoimaging of Blood-Brain Barrier Permeable (FDG) and Impermeable (FLT) Substrates After Intranasal (IN) Administration. ... This product is modified to meet the requirements for administration to small animals. A 1.5-2.0 mL sample is withdrawn from ...
  https://rd.springer.com/article/10.1208/s12248-017-0157-6
*  Anesthesia and Sedation in Chough (Pyrrhocorax pyrrhocorax) Following Intranasal Administration of Diazepam, Midazolam,...
Fallowing intranasal administration of the subjects, sedation or anesthesia was produced in all groups. Conclusion and Clinical ... Relevance-This study revealed that intranasal use of xylazine, diazepam and midazolame alone or combined with ketamine provides ... This study aimed to compare sedation efficacy in intranasal administration of xylazine, diazepam and midazolam with or without ... intranasal administration. Anesthesiology.1991;. 74(2):233-235.. 13. Robertson S-A, Eberhart S. Efficacy of the. intranasal ...
  http://www.ivsajournals.com/article_41019.html
*  Moderate leukocyte infiltration in the lower turbinate mucosa after a two-week intranasal administration of Mometasone Furoate,...
... rechercher des changements de la muqueuse nasale par microscopie optique après administration quotidienne par voie intra-nasale ... Moderate leukocyte infiltration in the lower turbinate mucosa after a two-week intranasal administration of Mometasone Furoate ... We used light microscopy to search for local changes of the nasal mucosa associated with daily intranasal administration of ... Conclusions: Intranasal treatment with MF, AZ or SC does not cause significant changes in the general architecture of the nasal ...
  http://ent-review.com/detail_en.lasso?id=87a74d77b882252e
*  Epitopes described in Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of...
Free resource for searching and exporting immune epitopes. Includes more than 95% of all published infectious disease, allergy, autoimmune, and transplant epitope data.
  http://www.iedb.org/pmId/8570667
*  Sumatriptan (intranasal route of administration) for acute migraine attacks in adults. - Nuffield Department of Clinical...
Intranasal administration may be preferable to oral for individuals experiencing nausea and/or vomiting, although it is ... AUTHORS' CONCLUSIONS: Intranasal sumatriptan is effective as an abortive treatment for acute migraine attacks, relieving pain, ... MAIN RESULTS: Twelve studies (4755 participants) compared intranasal sumatriptan with placebo or an active comparator. Most of ... OBJECTIVES: To determine the efficacy and tolerability of intranasal sumatriptan compared to placebo and other active ...
  https://www.ndcn.ox.ac.uk/publications/256351
*  Efficacy of Intranasal Fentanyl at Reducing Pain During Abscess Incision and Drainage (I&D) in Children - Full Text View -...
Patients will complete the FPS-R at four times during their medical encounter: (1) before analgesia administration, (2) ten ... Experimental: Intranasal Fentanyl Patients in this arm will receive intranasal Fentanyl (50 micrograms/mL) as their pre-I&D ... Efficacy of Intranasal Fentanyl at Reducing Pain During Abscess Incision and Drainage (I&D) in Children. The safety and ... Efficacy of Intranasal Fentanyl at Reducing Pain During Abscess Incision and Drainage (I&D) in Children. ...
  https://clinicaltrials.gov/show/NCT01549002
*  A Novel Intranasal Spray Device for the Administration of Nanoparticles to Rodents | Journal of Medical Devices | ASME DC
A Novel Intranasal Spray Device for the Administration of Nanoparticles to Rodents Justin E. Piazza, Chao Zhu, P. Ravi ... A Novel Intranasal Spray Device for the Administration of Nanoparticles to Rodents. ASME. J. Med. Devices. 2015;9(4):041001- ... Return to: A Novel Intranasal Spray Device for the Administration of Nanoparticles to Rodents ... Preparation and Brain Delivery After Intranasal Administration," Biomaterials, 27(18), pp. 3482-3490. [CrossRef] [PubMed] ...
  http://medicaldevices.asmedigitalcollection.asme.org/article.aspx?articleid=2468708&resultClick=1