Association between asthma and serum adiponectin concentration in women | Thorax
Adipose tissue, adipokines and inflammation. J Allergy Clin Immunol 2005;115:911-20. ... The dependent variable measured at the same time was current asthma status defined as (1) a subject report of taking a ... Background: The association of murine asthma with adiposity may be mediated by adiponectin, an anti-inflammatory adipokine with ... One of the anti-inflammatory adipokines is adiponectin. Although central (visceral) adipocytes are the most important source of ...http://thorax.bmj.com/content/63/10/877
Nicotinamide Phosphoribosyltransferase Summary Report | CureHunter
It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin). ... It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin). ... 07/01/2013 - "A significant correlation between visfatin concentrations and insulin resistance (HOMA at the time of the study) ...http://www.curehunter.com/public/keywordSummaryD054409-Nicotinamide-Phosphoribosyltransferase.do
NAMPT (nicotinamide phosphoribosyltransferase)
Using real-time PCR and Western blotting, NAMPT was overexpressed at the mRNA and protein levels in gastric cancer cells and ... A novel role for the adipokine visfatin/pre-B cell colony-enhancing factor 1 in prostate carcinogenesis.. ... Increased NAMPT expression was found in glioblastoma samples using cDNA microarray based expression profiling, real-time RT- ... Using quantitative one-step real time RT-PCR, circulating Nampt mRNAs in postoperative esophagectomy patients were upregulated ...http://atlasgeneticsoncology.org/Genes/GC_NAMPT.html
Vagal Hyperactivity Due to Ventromedial Hypothalamic Lesions Increases Adiponectin Production and Release | Diabetes
Real-time PCR was performed with a Real-Time PCR System (Applied Biosystems Japan, Tokyo, Japan) (31). Two independent ... ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol Metab 2002;13:84-89pmid:11854024. ... The MONA LISA hypothesis in the time of leptin. Recent Prog Horm Res 1998;53:95-117; discussion 117-118pmid:9769705. ... Adiponectin is an adipokine that plays an important role in preventing development of type 2 diabetes and cardiovascular ...http://diabetes.diabetesjournals.org/content/63/5/1637.full
Vitamin D and Vascular Health in Children - Full Text View - ClinicalTrials.gov
inflammatory markers [ Time Frame: 6 months ]. *adipokines [ Time Frame: 6 months ]. *nitric oxide metabolites [ Time Frame: 6 ... As a secondary objective, we will examine the vitamin D supplementation-induced effect on adipokines and inflammatory markers ... fasting glucose/fasting insulin ratio [ Time Frame: 6 months ]. Homeostasis Model of Assessment - Insulin Resistance (HOMA-IR) ... blood pressure, waist circumference, HDL cholesterol, triglycerides, and fasting blood glucose [ Time Frame: 6 months ]. ...https://clinicaltrials.gov/ct2/show/NCT01797302?term=%22Metabolic+Syndrome%22&lup_s=02%2F17%2F2013&lup_d=14&show_rss=Y&sel_rss=mod14
An Exercise RCT Targeting African-American Women With Metabolic Syndrome and High Risk for Breast Cancer - Full Text View -...
Biomarkers of breast cancer risk - adipokines [ Time Frame: 6 months ]. Serum leptin and adiponectin ... Waist circumference [ Time Frame: 6 months ]. Reduction in waist circumference. *Body Mass Index [ Time Frame: 6 months ]. ... Metabolic syndrome [ Time Frame: 6 months ]. Greater improvements in metabolic syndrome and metabolic syndrome components ... Body composition [ Time Frame: 6 months ]. Measured using DEXA scan: fat mass, lean mass ...https://clinicaltrials.gov/ct2/show/NCT02103140?term=%22Metabolic+Syndrome%22&lup_s=03%2F24%2F2014&lup_d=14&show_rss=Y&sel_rss=mod14
Testosterone Replacement in Metabolic Syndrome and Inflammation - Full Text View - ClinicalTrials.gov
Adipokines [ Time Frame: 3 months ]. Estimate of within subject absolute change in serum:. ADIPONECTIN, LEPTIN, RESISTIN. ... Fat-free mass [ Time Frame: 6 months ]. *Fat Mass [ Time Frame: 6 months ]. *HOMA-IR [ Time Frame: 6 months ]. *CRP [ Time ... Waist circumference [ Time Frame: 3 months ]. Waist circumference (cm). *IIEF [ Time Frame: 3 months ]. International Index of ... PSA (prostatic specific antigen) [ Time Frame: 3 months ]. PSA. *Hb, Htc [ Time Frame: 3 months ]. haemoglobin and haematocrit ...https://clinicaltrials.gov/ct2/show/NCT01123278?term=metabolic+syndrome+AND+syndrome+X+AND+insulin+resistance&recr=Open&no_unk=Y&cond=%22Metabolic+Syndrome+X%22&rank=13
Assess the Additional Weight Loss Effect of Orlistat Used in Combination With Sibutramine - Tabular View - ClinicalTrials.gov
Adipokines improvement [ Time Frame: with in 18weeks ]. Serum insulin, adiponectin, leptin, ghrelin, serum ostecalcin, urine ... Lipid profile [ Time Frame: with in 18weeks ]. Total cholesterol, HDL-C(high-density lipoprotein-cholesterol), LDL-C(low- ... Sibutramine monotherapy group would receive Sibutramine 10mg once daily and Orlistat placebo three times daily for 12 weeks; ... Orlistat and Sibutramine combination group: Sibutramine 1 capsule once daily + Orlistat 1 capsule three times daily ...https://clinicaltrials.gov/ct2/show/record/NCT01184560
New Frontiers on Bariatric Surgical Procedures: Classical Bypass for Type-2 Diabetic Patients With Obesity Grade I - Full Text...
Changes in seric free fatty acids, lipoproteins, adiponectin and other adipokines [ Time Frame: one month, 2 months, 3 months, ... Time Frame: 6 months and 1 year ]. *Improvement of insulin sensitivity as measured by insulin tolerance test [ Time Frame: 1 ... Improvement or reversal of type 2 diabetes mellitus [ Time Frame: 7 days, 14 days, 21 days, 1 month, 2 months, 3 months, six ... Changes in body weight and fat distribution after intervention [ Time Frame: 1 month, 2 months, 3 months, 6 months and 1 year ] ...https://clinicaltrials.gov/ct2/show/study/NCT00566189?view=record
Adipokine - Wikipedia
The first adipokine to be discovered was leptin in 1994. Since that time, hundreds of adipokines have been discovered. Members ... The adipokines, or adipocytokines (Greek adipo-, fat; cytos-, cell; and -kinos, movement) are cytokines (cell signaling ... Conde J, Scotece M, Gómez R, López V, Gómez-Reino JJ, Lago F, Gualillo O (2011). "Adipokines: biofactors from white adipose ... Lehr S, Hartwig S, Sell H (2012). "Adipokines: a treasure trove for the discovery of biomarkers for metabolic disorders". ...https://en.wikipedia.org/wiki/Adipokine
Assessing the Severity of Metabolic-related Liver Injuries in Aging HIV-monoinfected Patients - Full Text View - ClinicalTrials...
... adipokines) [ Time Frame: Within 6 months after all patients have completed the study ]. *Establish a diagnosis score based on ... Percentage of patients with NASH, fibrosis and cirrhosis on liver biopsy [ Time Frame: Within 6 months after all patients have ... Percentage of steatosis detected by MRI [ Time Frame: Within 6 months after all patients have completed MRI ]. ... Percentage of fibrosis or cirrhosis using non invasive markers and concordance of non invasive markers [ Time Frame: Within 6 ...https://clinicaltrials.gov/show/NCT02093754
The Carb-Sane Asylum: Adipocyte Size & Adipokine Secretion
There were stronglinear correlations for the secretion of adipokines over time. Secretion of leptin, IL-6, IL-8, TNF-. , ... Conclusions: The results clearly suggest that adipocyte size is an important determinant of adipokine secretion. There seems to ... Relationship between Adipocyte Size and Adipokine Expression and Secretion. Context: Adipocytes are known to release a variety ... Have you come across anything suggesting these adipokines stimulate the birth of new adipocytes? It would be the perfect ...http://carbsanity.blogspot.com/2010/10/adipocyte-size-adipokine-secretion.html
Effects of L-Carnitine on Postprandial Clearance of Triglyceride-rich Lipoproteins in HIV Patients on HAART - Full Text View -...
L-carnitine will impact upon the relationship between insulin and NEFA or adipokines in the postprandial state [ Time Frame: 6 ... L-carnitine supplementation will improve fasting TGRL levels and the postprandial response [ Time Frame: 6 weeks ]. ... Baseline TGRL metabolism and insulin, NEFA and adipokine levels. *Postprandial TGRL responses and the postprandial relationship ... Further, we showed a relationship between fasting insulin and postprandial adipokine levels. ...https://clinicaltrials.gov/show/NCT00386971?order=422
Acupuncture to Treat Insulin Resistance in Women With and Without Polycystic Ovary Syndrome - Full Text View - ClinicalTrials...
Change in circulating sex steroids, adipokines, lipids and inflammatory markers [ Time Frame: Day 1 and Week 5 ]. Mass ... Acupuncture (chronic i.e. 5 weeks treatment, 3 times per week) improve health related quality of life and symptoms of anxiety ... Acupuncture (acute and chronic i.e. 5 weeks treatment, 3 times per week) improves insulin sensitivity in overweight and obese ... Change in insulin signaling (muscle and adipose tissue) [ Time Frame: Day 1 and Week 5 ]. Western blot, RT-PCR ...https://clinicaltrials.gov/ct2/show/NCT01457209
Insulin Resistance in Smokers Undergoing Smoking Cessation - Full Text View - ClinicalTrials.gov
HOMA-IR index [ Time Frame: 8 weeks, 4 months, 6 months ]. *Adipokines [ Time Frame: 8 weeks, 4 months, 6 months ]. *Highly- ... Morning cortisol [ Time Frame: 8 weeeks, 4 months, 6 months ]. *IGF-1 [ Time Frame: 8 weeks, 4 months, 6 months ]. *Mean total ... Body mass index [ Time Frame: 8 weeks, 4 months, 6 months ]. *Body composition [ Time Frame: 8 weeks, 4 months, 6 months ]. * ... Body fat distribution [ Time Frame: 8 weeks, 4 months, 6 months ]. *Blood pressure [ Time Frame: 8 weeks, 4 months, 6 months ] ...https://clinicaltrials.gov/ct2/show/NCT00877513?recr=Open&cond=%22Insulin%22&rank=11
Beta Cell Restoration Through Fat Mitigation - Full Text View - ClinicalTrials.gov
Blood and urine biomarkers [ Time Frame: 0, 6, 12, 18, 24 months ]. adipokines, fatty acids ... Insulin sensitivity [ Time Frame: 0, 12, 24 months ]. ratio of clamp steady state glucose utilization to clamp steady state ... Maximum beta cell compensation [ Time Frame: 0, 12, 24 months ]. area under plasma C-peptide curve 0-10 minutes after arginine ... Insulin responses to oral glucose [ Time Frame: 0, 12, 24 months ]. 30-min insulin and C-peptide responses and modeled ...https://clinicaltrials.gov/ct2/show/NCT01763346
Effects of Intentional Weight Loss Interventions in Chronic Kidney Disease - Full Text View - ClinicalTrials.gov
Changes in markers of insulin resistance and inflammation, adipokines, and body composition. [ Time Frame: 6 months ]. Weight ... Patients will undergo adipokines, markers of inflammation,insulin resistance, renal function, bioimpedance analysis,DEXA ... Changes in renal function using iothalamate studies and urinary protein excretion using 24 hour urinary studies [ Time Frame: 6 ...https://clinicaltrials.gov/ct2/show/NCT01180101?recr=Open&cond=%22Renal+Insufficiency%2C+Chronic%22&rank=13
Corticosteroid-induced Lipodystrophy and Adipokines - Tabular View - ClinicalTrials.gov
Expression of leptin, IL6, TNFa, 11bHSD1, SREBP1c and PPARg in adipocytes [ Time Frame: at the inclusion and M3 visits ] ... Corticosteroid-induced Lipodystrophy and Adipokines. Official Title Study of Histological and Adipokines Expression Variations ... Methods: At treatment initiation and 3 months after: comparison of fat sample mRNA expression of adipokines (adiponectin, ... Plasma levels of adiponectin, leptin, sTNFR1, and IL6 [ Time Frame: at the inclusion and M3 visits ] ...https://clinicaltrials.gov/ct2/show/record/NCT00822042
Role of Vitamin D in the Prevention and Treatment of Diseases Associated With Insulin Resistance - Full Text View -...
Changes from baseline in cytokines/adipokines at 6 months between placebo and vitamin D groups [ Time Frame: 0 and 6 months ]. ... Change from baseline in blood pressure [ Time Frame: 0 and 6 months ]. *Change from baseline in lipid profile [ Time Frame: 0 ... Change from baseline in anthropometry (weight, waist circumference and fat mass by bioimpedance analysis) [ Time Frame: 0 and 6 ...https://clinicaltrials.gov/ct2/show/NCT01779908
Inflammation, a Link between Obesity and Cardiovascular Disease
... at the current time, whether RBP4 functions as an adipokine in humans and exerts metabolic effects on glucose metabolism ... At the present time, the role of visfatin in the modulation of glucose metabolism, as well as its ability to bind to the ... At the present time, CVD is recognized as a chronic inflammatory condition of the vessel wall that results from the ... Adipokines and incident type 2 diabetes in an aboriginal Canadian population: the Sandy Lake Health and Diabetes Project. ...http://pubmedcentralcanada.ca/pmcc/articles/PMC2929614/
Study of the Effect of Diabetes on the Incidence and the Extent of Coronary Artery Disease - Full Text View - ClinicalTrials.gov
Time Perspective:. Cross-Sectional. Official Title:. The Role of Newer and Traditional Risk Factors in the Development, Extent ... The incidence, extent and clinical manifestation of coronary artery disease and the circulating levels of hs-CRP, adipokines ... Time Frame: Up to four years on average. ]. We will investigate the incidence, extent and clinical manifestation of coronary ... Time Frame: Up to 4 years on average. ]. To associate the incidence, extent and clinical manifestation of coronary artery ...https://clinicaltrials.gov/ct2/show/NCT01585948
Deficiency of Cbl-b Gene Enhances Infiltration and Activation of Macrophages in Adipose Tissue and Causes Peripheral Insulin...
Three days later, the expression of adipokine transcripts was measured by real-time RT-PCR. The fluorescence ratio of the ... Real-time RT-PCR.. Total RNA was subjected to real-time RT-PCR with SYBR Green dye by using an ABI7300 real-time PCR system ( ... Expression of cytokines and adipokines in white adipose tissue. A-C: Expression levels of cytokines (A and B) and adipokine (C ... Plasma insulin concentration of 30-week-old Cbl-b−/− mice was higher than that of Cbl-b+/+ mice before and at every time point ...http://diabetes.diabetesjournals.org/content/56/10/2511.full
Adipose Tissue and Adipokines in Health and Disease, Book by A.P. Goldberg (Paperback) | chapters.indigo.ca
Buy the Paperback Book Adipose Tissue and Adipokines in Health and Disease by A.P. Goldberg at Indigo.ca, Canada's largest ... Adipose Tissue and Adipokines in Health and Disease. Foreword byA.P. Goldberg, S.K. FriedEditorGiamila Fantuzzi. Paperback , ... Title:Adipose Tissue and Adipokines in Health and DiseaseFormat:PaperbackDimensions:422 pagesPublished:October 17, 2011 ... Adipose Tissue and Adipokines in Health and Disease presents a comprehensive survey of adipose tissue, its physiological ...https://www.chapters.indigo.ca/en-ca/books/adipose-tissue-and-adipokines-in/9781617377419-item.html
Correlation Between Various Adipokines and Vascular Inflammation Measured by Positron Emission Tomography (PET) With 18F-fluoro...
Time Perspective: Cross-Sectional. Official Title:. Correlation Between Various Adipokines and Vascular Inflammation Measured ... Circulating serum A-FABP levels [ Time Frame: 12 weeks ]. *Circulating serum leptin levels [ Time Frame: 12weeks ]. * ... The purpose of the study is to examine the relationship between various adipokine levels and PET imaging at the cross section ... Correlation Between Various Adipokines and Vascular Inflammation Measured by Positron Emission Tomography (PET) With 18F-fluoro ...https://clinicaltrials.gov/ct2/show/NCT01150006
Obesity-associated morbidity - Wikipedia
Compared to men with a BMI of 21-23, men with a BMI of 30-35 have 2.3 times more gout, and men with a BMI of greater than 35 ... The result is reduction of the testis' production of testosterone and a further increase in adipokine levels. This then feeds ... Obese individuals are twice to four times more likely to have lower back pain than their normal weight peers. In women, class ... The risk of hypertension is 5 times higher in the obese as compared to those of normal weight. A definitive link between ...https://en.wikipedia.org/wiki/Obesity-associated_morbidity