Association between asthma and serum adiponectin concentration in women | Thorax
Adipose tissue, adipokines and inflammation. J Allergy Clin Immunol 2005;115:911-20. ... The dependent variable measured at the same time was current asthma status defined as (1) a subject report of taking a ... Background: The association of murine asthma with adiposity may be mediated by adiponectin, an anti-inflammatory adipokine with ... One of the anti-inflammatory adipokines is adiponectin. Although central (visceral) adipocytes are the most important source of ...http://thorax.bmj.com/content/63/10/877
Nicotinamide Phosphoribosyltransferase Summary Report | CureHunter
It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin). ... It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin). ... 07/01/2013 - "A significant correlation between visfatin concentrations and insulin resistance (HOMA at the time of the study) ...http://www.curehunter.com/public/keywordSummaryD054409-Nicotinamide-Phosphoribosyltransferase.do
NAMPT (nicotinamide phosphoribosyltransferase)
Using real-time PCR and Western blotting, NAMPT was overexpressed at the mRNA and protein levels in gastric cancer cells and ... A novel role for the adipokine visfatin/pre-B cell colony-enhancing factor 1 in prostate carcinogenesis.. ... Increased NAMPT expression was found in glioblastoma samples using cDNA microarray based expression profiling, real-time RT- ... Using quantitative one-step real time RT-PCR, circulating Nampt mRNAs in postoperative esophagectomy patients were upregulated ...http://atlasgeneticsoncology.org/Genes/GC_NAMPT.html
Vagal Hyperactivity Due to Ventromedial Hypothalamic Lesions Increases Adiponectin Production and Release | Diabetes
Real-time PCR was performed with a Real-Time PCR System (Applied Biosystems Japan, Tokyo, Japan) (31). Two independent ... ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol Metab 2002;13:84-89pmid:11854024. ... The MONA LISA hypothesis in the time of leptin. Recent Prog Horm Res 1998;53:95-117; discussion 117-118pmid:9769705. ... Adiponectin is an adipokine that plays an important role in preventing development of type 2 diabetes and cardiovascular ...http://diabetes.diabetesjournals.org/content/63/5/1637.full
These differentially expressed adipokines include leptin (4,5), plasminogen activator inhibitor-1 (6), and interleukin-6 (7). ... Human visfatin gene expression was measured by quantitative real-time RT-PCR in a fluorescent temperature cycler using the ... Recently, visfatin was identified as an adipokine, which is predominantly secreted from visceral adipose tissue both in humans ... Hug C, Lodish HF: Visfatin: a new adipokine. Science307 :366 -367,2005. ...http://diabetes.diabetesjournals.org/content/54/10/2911
RBP4, rat recombinant protein - Retinol Binding Protein 4, Plasma retinol-binding protein, PRBP, RBP - Buy Now! |Abgent
A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. ... Certify that your antibodies work, while saving time and money. Abgent's experienced staff custom validates more than 1,000 ... Expression-ready clones are convenient solution that decreases the time required to start an experiment and increases the ... team employs the latest in instrumentation and specialized synthetic techniques to deliver high quality products on time at a ...http://www.abgent.com/products/PBV11176r-RBP4-rat-recombinant-protein
Design and development of a peptide-based adiponectin receptor agonist for cancer treatment | BMC Biotechnology | Full Text
Hu PF, Bao JP, Wu LD: The emerging role of adipokines in osteoarthritis: a narrative review. Mol Biol Rep. 2010, 38 (2): 873- ... Hilpert K, Winkler DF, Hancock RE: Peptide arrays on cellulose support: SPOT synthesis, a time and cost efficient method for ... Analysis was performed using a MALDI time-of-flight tandem mass spectrometer (MALDI-TOF/TOF-MS, 4700 proteomic analyzer, ... Schaffler A, Scholmerich J, Buechler C: Mechanisms of disease: adipokines and breast cancer - endocrine and paracrine ...https://bmcbiotechnol.biomedcentral.com/articles/10.1186/1472-6750-11-90
Vitamin D and Vascular Health in Children - Full Text View - ClinicalTrials.gov
inflammatory markers [ Time Frame: 6 months ]. *adipokines [ Time Frame: 6 months ]. *nitric oxide metabolites [ Time Frame: 6 ... As a secondary objective, we will examine the vitamin D supplementation-induced effect on adipokines and inflammatory markers ... fasting glucose/fasting insulin ratio [ Time Frame: 6 months ]. Homeostasis Model of Assessment - Insulin Resistance (HOMA-IR) ... blood pressure, waist circumference, HDL cholesterol, triglycerides, and fasting blood glucose [ Time Frame: 6 months ]. ...https://clinicaltrials.gov/ct2/show/NCT01797302?term=%22Metabolic+Syndrome%22&lup_s=02%2F17%2F2013&lup_d=14&show_rss=Y&sel_rss=mod14
An Exercise RCT Targeting African-American Women With Metabolic Syndrome and High Risk for Breast Cancer - Full Text View -...
Biomarkers of breast cancer risk - adipokines [ Time Frame: 6 months ]. Serum leptin and adiponectin ... Waist circumference [ Time Frame: 6 months ]. Reduction in waist circumference. *Body Mass Index [ Time Frame: 6 months ]. ... Metabolic syndrome [ Time Frame: 6 months ]. Greater improvements in metabolic syndrome and metabolic syndrome components ... Body composition [ Time Frame: 6 months ]. Measured using DEXA scan: fat mass, lean mass ...https://clinicaltrials.gov/ct2/show/NCT02103140?term=%22Metabolic+Syndrome%22&lup_s=03%2F24%2F2014&lup_d=14&show_rss=Y&sel_rss=mod14
Testosterone Replacement in Metabolic Syndrome and Inflammation - Full Text View - ClinicalTrials.gov
Adipokines [ Time Frame: 3 months ]. Estimate of within subject absolute change in serum:. ADIPONECTIN, LEPTIN, RESISTIN. ... Fat-free mass [ Time Frame: 6 months ]. *Fat Mass [ Time Frame: 6 months ]. *HOMA-IR [ Time Frame: 6 months ]. *CRP [ Time ... Waist circumference [ Time Frame: 3 months ]. Waist circumference (cm). *IIEF [ Time Frame: 3 months ]. International Index of ... PSA (prostatic specific antigen) [ Time Frame: 3 months ]. PSA. *Hb, Htc [ Time Frame: 3 months ]. haemoglobin and haematocrit ...https://clinicaltrials.gov/ct2/show/NCT01123278?term=metabolic+syndrome+AND+syndrome+X+AND+insulin+resistance&recr=Open&no_unk=Y&cond=%22Metabolic+Syndrome+X%22&rank=13
Assess the Additional Weight Loss Effect of Orlistat Used in Combination With Sibutramine - Tabular View - ClinicalTrials.gov
Adipokines improvement [ Time Frame: with in 18weeks ]. Serum insulin, adiponectin, leptin, ghrelin, serum ostecalcin, urine ... Lipid profile [ Time Frame: with in 18weeks ]. Total cholesterol, HDL-C(high-density lipoprotein-cholesterol), LDL-C(low- ... Sibutramine monotherapy group would receive Sibutramine 10mg once daily and Orlistat placebo three times daily for 12 weeks; ... Orlistat and Sibutramine combination group: Sibutramine 1 capsule once daily + Orlistat 1 capsule three times daily ...https://clinicaltrials.gov/ct2/show/record/NCT01184560
Pre-, Peri- and Postnatal Programming and Origins of Disease: Early Targeting the Epidemics of Allergy and Overweight - Full...
Adipokines [ Time Frame: Up to 13 years ]. *Amount of crying in minutes [ Time Frame: Up to 1 year ]. Crying minutes per day ... GHbA1c [ Time Frame: Up to 13 years ]. *Fatty acids [ Time Frame: Up to 13 years ]. *Lipoproteins [ Time Frame: Up to 13 years ... Plasma glucose [ Time Frame: Up to 13 years ]. *Cytokines in peripheral blood [ Time Frame: Up to 13 years ]. *Cytokine profile ... Weight gain [ Time Frame: Up to 13 years ]. *Number of patients with chronic inflammatory disease [ Time Frame: Up to 13 years ...https://clinicaltrials.gov/ct2/show/NCT00167700?term=Allergy&recr=Open&rank=43
New Frontiers on Bariatric Surgical Procedures: Classical Bypass for Type-2 Diabetic Patients With Obesity Grade I - Full Text...
Changes in seric free fatty acids, lipoproteins, adiponectin and other adipokines [ Time Frame: one month, 2 months, 3 months, ... Time Frame: 6 months and 1 year ]. *Improvement of insulin sensitivity as measured by insulin tolerance test [ Time Frame: 1 ... Improvement or reversal of type 2 diabetes mellitus [ Time Frame: 7 days, 14 days, 21 days, 1 month, 2 months, 3 months, six ... Changes in body weight and fat distribution after intervention [ Time Frame: 1 month, 2 months, 3 months, 6 months and 1 year ] ...https://clinicaltrials.gov/ct2/show/study/NCT00566189?view=record
Paleo Versus Healthy ADA Diets for Treatment of Polycystic Ovarian Syndrome (PCOS) | Clinical Research Trial Listing (...
CBC, Chemical profile; blood lipids; cardiovascular risk factors and inflammatory cytokines and adipokines (time 0, week 16, ... Androgen levels (times 0, weeks 16, 32): Two serum samples will be obtained 30 minutes apart.. Serum will be isolated and ... Samples will be drawn at time 0; week 8; week 16; week 24 and week 32. We will collect serum, plasma and urine at all these ... Systemic oxidative stress (time 0, weeks 16, 32): we will measure 4 serum markers of oxidative stress; protein carbonyls (a ...http://www.centerwatch.com/clinical-trials/listings/172685/polycystic-ovarian-syndrome-paleo-versus-healthy-ada/?radius=50
Adipokine - Wikipedia
The first adipokine to be discovered was leptin in 1994. Since that time, hundreds of adipokines have been discovered. Members ... The adipokines, or adipocytokines (Greek adipo-, fat; cytos-, cell; and -kinos, movement) are cytokines (cell signaling ... Conde J, Scotece M, Gómez R, López V, Gómez-Reino JJ, Lago F, Gualillo O (2011). "Adipokines: biofactors from white adipose ... Lehr S, Hartwig S, Sell H (2012). "Adipokines: a treasure trove for the discovery of biomarkers for metabolic disorders". ...https://en.wikipedia.org/wiki/Adipokine
Assessing the Severity of Metabolic-related Liver Injuries in Aging HIV-monoinfected Patients - Full Text View - ClinicalTrials...
... adipokines) [ Time Frame: Within 6 months after all patients have completed the study ]. *Establish a diagnosis score based on ... Percentage of patients with NASH, fibrosis and cirrhosis on liver biopsy [ Time Frame: Within 6 months after all patients have ... Percentage of steatosis detected by MRI [ Time Frame: Within 6 months after all patients have completed MRI ]. ... Percentage of fibrosis or cirrhosis using non invasive markers and concordance of non invasive markers [ Time Frame: Within 6 ...https://clinicaltrials.gov/show/NCT02093754
The Carb-Sane Asylum: Adipocyte Size & Adipokine Secretion
There were stronglinear correlations for the secretion of adipokines over time. Secretion of leptin, IL-6, IL-8, TNF-. , ... Conclusions: The results clearly suggest that adipocyte size is an important determinant of adipokine secretion. There seems to ... Relationship between Adipocyte Size and Adipokine Expression and Secretion. Context: Adipocytes are known to release a variety ... Have you come across anything suggesting these adipokines stimulate the birth of new adipocytes? It would be the perfect ...http://carbsanity.blogspot.com/2010/10/adipocyte-size-adipokine-secretion.html
Even- and odd-chain saturated fatty acids in serum phospholipids are differentially associated with adipokines
Results Even- and odd-chain saturated fatty acids were differentially associated with adipokines. Higher levels of even-chain ... Objective We examined the associations of saturated fatty acids in serum phospholipids with circulating levels of adipokines ... Multiple linear regression analysis was performed to assess the association between saturated fatty acids and adipokines, with ... Conclusions The results suggest that even- and odd-chain saturated fatty acids are differentially associated with adipokine ...https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0178192
Effects of L-Carnitine on Postprandial Clearance of Triglyceride-rich Lipoproteins in HIV Patients on HAART - Full Text View -...
L-carnitine will impact upon the relationship between insulin and NEFA or adipokines in the postprandial state [ Time Frame: 6 ... L-carnitine supplementation will improve fasting TGRL levels and the postprandial response [ Time Frame: 6 weeks ]. ... Baseline TGRL metabolism and insulin, NEFA and adipokine levels. *Postprandial TGRL responses and the postprandial relationship ... Further, we showed a relationship between fasting insulin and postprandial adipokine levels. ...https://clinicaltrials.gov/show/NCT00386971?order=422
Acupuncture to Treat Insulin Resistance in Women With and Without Polycystic Ovary Syndrome - Full Text View - ClinicalTrials...
Change in circulating sex steroids, adipokines, lipids and inflammatory markers [ Time Frame: Day 1 and Week 5 ]. Mass ... Acupuncture (chronic i.e. 5 weeks treatment, 3 times per week) improve health related quality of life and symptoms of anxiety ... Acupuncture (acute and chronic i.e. 5 weeks treatment, 3 times per week) improves insulin sensitivity in overweight and obese ... Change in insulin signaling (muscle and adipose tissue) [ Time Frame: Day 1 and Week 5 ]. Western blot, RT-PCR ...https://clinicaltrials.gov/ct2/show/NCT01457209
Insulin Resistance in Smokers Undergoing Smoking Cessation - Full Text View - ClinicalTrials.gov
HOMA-IR index [ Time Frame: 8 weeks, 4 months, 6 months ]. *Adipokines [ Time Frame: 8 weeks, 4 months, 6 months ]. *Highly- ... Morning cortisol [ Time Frame: 8 weeeks, 4 months, 6 months ]. *IGF-1 [ Time Frame: 8 weeks, 4 months, 6 months ]. *Mean total ... Body mass index [ Time Frame: 8 weeks, 4 months, 6 months ]. *Body composition [ Time Frame: 8 weeks, 4 months, 6 months ]. * ... Body fat distribution [ Time Frame: 8 weeks, 4 months, 6 months ]. *Blood pressure [ Time Frame: 8 weeks, 4 months, 6 months ] ...https://clinicaltrials.gov/ct2/show/NCT00877513?recr=Open&cond=%22Insulin%22&rank=11
Beta Cell Restoration Through Fat Mitigation - Full Text View - ClinicalTrials.gov
Blood and urine biomarkers [ Time Frame: 0, 6, 12, 18, 24 months ]. adipokines, fatty acids ... Insulin sensitivity [ Time Frame: 0, 12, 24 months ]. ratio of clamp steady state glucose utilization to clamp steady state ... Maximum beta cell compensation [ Time Frame: 0, 12, 24 months ]. area under plasma C-peptide curve 0-10 minutes after arginine ... Insulin responses to oral glucose [ Time Frame: 0, 12, 24 months ]. 30-min insulin and C-peptide responses and modeled ...https://clinicaltrials.gov/ct2/show/NCT01763346
Effects of Intentional Weight Loss Interventions in Chronic Kidney Disease - Full Text View - ClinicalTrials.gov
Changes in markers of insulin resistance and inflammation, adipokines, and body composition. [ Time Frame: 6 months ]. Weight ... Patients will undergo adipokines, markers of inflammation,insulin resistance, renal function, bioimpedance analysis,DEXA ... Changes in renal function using iothalamate studies and urinary protein excretion using 24 hour urinary studies [ Time Frame: 6 ...https://clinicaltrials.gov/ct2/show/NCT01180101?recr=Open&cond=%22Renal+Insufficiency%2C+Chronic%22&rank=13
Corticosteroid-induced Lipodystrophy and Adipokines - Tabular View - ClinicalTrials.gov
Expression of leptin, IL6, TNFa, 11bHSD1, SREBP1c and PPARg in adipocytes [ Time Frame: at the inclusion and M3 visits ] ... Corticosteroid-induced Lipodystrophy and Adipokines. Official Title Study of Histological and Adipokines Expression Variations ... Methods: At treatment initiation and 3 months after: comparison of fat sample mRNA expression of adipokines (adiponectin, ... Plasma levels of adiponectin, leptin, sTNFR1, and IL6 [ Time Frame: at the inclusion and M3 visits ] ...https://clinicaltrials.gov/ct2/show/record/NCT00822042
CTRP7 deletion attenuates obesity-linked glucose intolerance, adipose tissue inflammation, and hepatic stress. - PubMed - NCBI
Expression and circulating adipokine levels in HFD-fed WT and Ctrp7-KO male mice. A: quantitative real-time PCR analysis of ... Real-time PCR data were normalized to B2M or 36B4. *P , 0.05; **P , 0.01; ***P , 0.005. Col, collagen; Sod, superoxide ... Real-time PCR data were normalized to B2M. *P , 0.05. Mgl2, macrophage galactose N-acetyl-galactosamine specific lectin 2; Tgf- ... expression of adipokine genes in gonadal adipose tissue of WT (n = 11) and KO (n = 11) male mice fed a HFD. Real-time PCR data ...https://www.ncbi.nlm.nih.gov/pubmed/28223291