Bordetella pertussis filamentous hemagglutinin interacts with a leukocyte signal transduction complex and stimulates bacterial...
... filamentous hemagglutinin interacts with a leukocyte signal transduction complex and stimulates bacterial adherence to monocyte ... Enhancement requires a monocyte signal transduction complex, composed of leukocyte response integrin (alpha? beta 3) and ... Bordetella pertussis, the causative agent of whooping cough, adheres to human monocytes/macrophages by means of a bacterial ... filamentous hemagglutinin interacts with a leukocyte signal transduction complex and stimulates bacterial adherence to monocyte ...http://jem.rupress.org/content/180/4/1225
8/7- Atherosclerosis Flashcards by Kathryn Kudlaty | Brainscape
2. Adherence of monocytes to EC. - Clustering of monocytes/macrophages. - LDL oxidation and accumulation in monocytes -, ... Lipid rich (monocytes) foam cells. 3. Production of GFs and inflammatory cytokines by damaged EC, platelets, and macrophages ... GFs derived from platelets (PDGF), EC, and monocytes stimulate smooth muscle cell proliferation and migration into the intima ...https://www.brainscape.com/flashcards/8-7-atherosclerosis-4057905/packs/6029491
Pharmaceuticals | Free Full-Text | Cannabinoids and Viral Infections | HTML
increased adherence for monocytes. uncoupled NO release, inhibited NO. human saphenous vein or internal thoracic artery; ... and monocytes were stickier on endothelial cells [57,58]. In one study, KHSV was more likely to exit latency and enter lytic ... and anandamide increases endothelial adhesion of monocytes: Uncoupling of nitric oxide release. J. Cardiovasc. Pharmacol. 1998 ...http://www.mdpi.com/1424-8247/3/6/1873/htm
CCL4L1 Gene - GeneCards | CC4L Protein | CC4L Antibody
Monocyte Adherence-Induced Protein 5-Alpha 3 4 * Macrophage Inflammatory Protein 1-Beta 3 4 ... Inhibits HIV replication in peripheral blood monocytes that express CCR5. *CC4L_HUMAN,Q8NHW4 ...http://www.genecards.org/cgi-bin/carddisp.pl?gene=CCL4L1&rf=/home/genecards/current/website/carddisp.pl&many_orthologs=all
Table of Contents - October 01, 1985, 135 (4) | The Journal of Immunology
Human monocyte adherence to cultured vascular endothelium: monoclonal antibody-defined mechanisms. W J Wallis, P G Beatty, H D ...http://www.jimmunol.org/content/135/4
Bone Marrow-Specific Deficiency of Nuclear Receptor Nur77 Enhances AtherosclerosisNovelty and Significance | Circulation...
Adherence of Ly6C+ Monocytes to Activated Endothelial Cells. Human umbilical cord endothelial cells were isolated.2 Cells were ... Identification of novel mediators of NF-kappaB through genome-wide survey of monocyte adherence-induced genes. J Leukoc Biol. ... After 3 hours, nonadherent cells were removed and monocyte adherence was quantified. ... monocyte chemotactic protein-1. NFκB. nuclear factor kappa-light-chain-enhancer of activated B cells. NIK. NFκB-inducing kinase ...http://circres.ahajournals.org/content/110/3/428
The Expression of NF-κB in the Glomerulus of Hyperlipidemia Rats
Hyperlipidemia could increase monocyte adherence to vascular endothelium. This process is intermediated by MCP-112. Monocyte ... MCP-1 is crucial in recruiting and activating monocytes, mast cells and basophils during inflammation . MCP-1 is produced ... R. K. Tangirala, K. Murao and O. Quehenberger, "Regulation of Expression of the Human Monocyte Chemotactic Protein-1 Receptor ( ... and the level of monocyte chemoattractant protein-1 (MCP-1) in hyperlipidemia rats. Methods: Rats were given with high fat diet ...http://file.scirp.org/Html/q1%202100053_3924.htm
Atherosclerosis facts, information, pictures | Encyclopedia.com articles about Atherosclerosis
NO also inhibits clot formation, and adherence of monocytes to the vessel. It also inhibits the growth of vascular smooth- ... The monocytes migrate into the vessel wall, where they begin to accumulate cholesterol. They become engorged by cholesterol in ... White blood cells (specifically monocytes and T-lymphocytes) begin to stick to the lining of the vessel, and to infiltrate the ...https://www.encyclopedia.com/medicine/diseases-and-conditions/pathology/atherosclerosis
Increases in CD4+ T lymphocytes, macrophages, neutrophils and interleukin 8 positive cells in the airways of patients with...
1992) Increased adherence of monocytes to fibronectin in bronchiectasis. Regulatory effects of bacterial lipopolysaccharide and ... of these cells into foci of infection and inflammation include enhanced CD11/CD18 integrin mediated adherence of monocytes to ...http://thorax.bmj.com/content/53/8/685
Adhesion of Monocytes to Arterial Endothelium and Initiation of Atherosclerosis Are Critically Dependent on Vascular Cell...
Apo A-I inhibits foam cell formation in apo E-deficient mice after monocyte adherence to endothelium. J Clin Invest. 1999; 104 ... Figure 2. Effect of VCAM-1 on monocyte adherence and atherosclerotic lesion area in apoE−/− mice. A, Quantification of CD11a+ ... Vcam1 gene dosage affected endothelial VCAM-1 expression and the subsequent monocyte adherence to lesion-prone areas of the ... This suggests that VCAM-1 plays an important role in monocyte adherence to arterial endothelium during early atherogenesis. ...http://atvb.ahajournals.org/content/21/10/1662
Increased Expression of Neutrophil and Monocyte Adhesion Molecules LFA-1 and Mac-1 and Their Ligand ICAM-1 and VLA-4 Throughout...
Furthermore, this adherence could lead to the enhancement of monocyte tissue factor expression due to engagement of Mac-1 ... LFA-1 and Mac-1 are beta2-integrins that promote the adherence of neutrophils and monocytes to ICAM-1 on the endothelial cell ... 1993) Monocyte adherence to human vascular endothelium. J Leukocyte Biol 54:363-378. ... Monocyte adhesion, if compounded by enhancement of monocyte tissue factor expression due to engagement of Mac-1 receptor, as ...http://www.onlinejacc.org/content/31/1/120
Patente US7429488 - Method for processing lipoaspirate cells - Google Patentes
Purification of human monocytes by adherence to polymeric fluorocarbon. Characterization of the monocyte-enriched cell fraction ... Differential adherence has also been applied to positive selection of monocytes (Berdel, W. E., et al., ... Adherence to plastic followed by a short period of cell expansion has also been applied in bone marrow-derived adult stem cell ... 20(6): p. 530-41). This approach (with or without differential adherence to the tissue culture plastic) could be applied to a ...http://www.google.es/patents/US7429488?dq=flatulence
Phase contrast images indicate the inhibition of PMA-induced monocyte adherence by metformin treatment after 48 h. ... Metformin inhibits monocyte-to-macrophage differentiation via AMPK-mediated inhibition of STAT3 activation: potential role in ... Specifically, they concluded that "the AMPK-STAT3 axis plays a pivotal role in regulating monocyte-to-macrophage ... inhibit monocyte-to-macrophage differentiation." The experiments allude to a variety of molecular mechanisms that metformin ...http://diabetes.diabetesjournals.org/content/64/6/1869
Ptk2b - Protein-tyrosine kinase 2-beta - Mus musculus (Mouse) - Ptk2b gene & protein
In monocytes, adherence to substrata is required for tyrosine phosphorylation and kinase activation. Angiotensin II, ...http://www.uniprot.org/uniprot/Q9QVP9
Patente US5213970 - Method for obtaining soluble antitumor factor - Google Patentes
... obtained by the precise activation of cells of monocyte/macrophage lineage. Monocytes are isolated in the absence of endotoxin ... 3. Role of Adherence on Monocyte Production of HMT. In a single experiment, monocytes at a density of 1 106 /ml were seeded in ... Thus the poor adherence which monocytes express on a polypropylene surface does not effect their ability to product HMT in ... Monocytes were seeded in 24-well plates (1 106 cells/well) and were washed after adherence. Actinomycin D, cycloheximide, or ...http://www.google.es/patents/US5213970
GRP78 Upregulation by Atheroprone Shear Stress Via p38-, α2β1-Dependent Mechanism in Endothelial Cells | Arteriosclerosis,...
Expression of ICAM-1 and VCAM-1 and monocyte adherence in arteries exposed to altered shear stress. Arterioscler Thromb Vasc ...http://atvb.ahajournals.org/content/28/8/1534
Neonatal care, premature birth, and other infant studies sub-cluster 73
Monocyte adherence is important in localizing cells at sites of infection and is associated with enhanced antimicrobial ... We isolated cord blood monocytes from preterm and full-term infants to study their ... ...http://www.biomedsearch.com/cluster/4/Neonatal-care-premature-birth-and-other-infant-studies/sub-73-p8.html
In Hypercholesterolemia, Lower Peripheral Monocyte Count Is Unique Among the Major Predictors of Atherosclerosis |...
In view of the abundant convincing evidence for the enhanced monocyte adherence in hypercholesterolemia,1 2 4 8 9 10 11 22 23 ... some studies have noted that monocyte adherence, or chemotaxis, is reduced in diabetes.42 43 Therefore, increased monocyte ... Direct potentiation of monocyte adherence caused by smoking remains controversial4 12 26 but is unlikely to be a major cause. A ... Cigarette smoking increases monocyte adherence to cultured endothelial cell monolayer. Biochem Biophys Res Commun.. 1994;203: ...http://atvb.ahajournals.org/content/16/2/256
A vascular biology network model focused on inflammatory processes to investigate atherogenesis and plaque instability |...
The HYP with the upstream node monocyte adherence, scored for the Mm_Ao_78w_ApoE_vs_wt dataset. This HYP contains 87 measured ... "monocyte adherence" and "kaof(Chuk)" (Additional file8: Figure S3a-d).. ... Intact endothelium from ABCG1-deficient mice has been shown to exhibit 4-fold increases in monocyte adhesion. Other lipid ... HYPs O/L with EC-Monocyte Interaction N° HYPs O/L with Foam Cell Formation N° HYPs O/L with SMC Activation N° HYPs O/L with ...https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-12-185
Shear Stress Regulates Angiotensin Type 1 Receptor Expression in Endothelial Cells | Circulation Research
Expression of ICAM-1 and VCAM-1 and monocyte adherence in arteries exposed to altered shear stress. Arterioscler Thromb Vasc ... ACE inhibition lowers angiotensin-II-induced monocyte adhesion to HUVEC by reduction of p65 translocation and AT 1 expression. ... 35 facilitating monocyte adhesion. Ang II was also found to reduce the availability of NO in ECs through an AT1R-dependent ... monocyte chemoattractant protein-1, interleukins), and growth factors that contribute to leukocyte recruitment and infiltration ...http://circres.ahajournals.org/content/105/9/869
Transient and Steady-State Effects of Shear Stress on Endothelial Cell Adherens Junctions | Circulation Research
Expression of ICAM-1 and VCAM-1 and monocyte adherence in arteries exposed to altered shear stress. Arterioscler Thromb Vasc ... Monocyte adhesion and changes in endothelial cell number, morphology, and F-actin distribution elicited by low shear stress in ... Changes in the distribution of LFA-1, catenins, and F-actin during transendothelial migration of monocytes in culture. J Cell ...http://circres.ahajournals.org/content/85/6/504
Inhibition of Nitric Oxide Biosynthesis Promotes P-selectin Expression in Platelets | Arteriosclerosis, Thrombosis, and...
... which promote PMN adherence to the endothelium.6 7 l-Arginine/NO can also attenuate monocyte adherence to the vascular ... PMN adherence was markedly enhanced by endothelial stimulation with either thrombin (2 U/mL), l-NAME (1 mmol/L), thrombin plus ... Labeled, autologous PMN adherence to feline coronary artery endothelium after stimulation by l-NAME (1 mmol/L) with or without ... Adherence of Nonstimulated PMNs to l-NAME-Stimulated Feline Coronary Artery Endothelium: Role of NO Inhibition. We then ...http://atvb.ahajournals.org/content/15/11/2068
Human TCR-αβ+ CD4− CD8− T Cells Can Derive from CD8+ T Cells and Display an Inflammatory Effector Phenotype | The Journal of...
C to allow monocyte adherence. Next, wells were washed twice with PBS and autologous CFSE-labeled T cells were added into the ... separated from autologous monocytes by a permeable membrane (0.4 μm pores); in the same well with autologous monocytes. ∗, p , ... Cell contact rather than monocyte-derived soluble factors was necessary to obtain this effect, because when monocytes and T ... 1⇑B). Additional work is needed to identify the monocyte-derived molecule(s) that induce CD8 T cells to become DN (Fig. 2⇑D). ...http://www.jimmunol.org/content/183/7/4675
US5437864A - Method of inhibiting blood coagulation in extracorporeal circulation by inhibiting human tissue factor -...
During SECC, there is a preferential adherence of monocytes and neutrophils to the oxygenator interface. Based on the ... Monocytes from the standing control sample at 6 hours expressed Mac-1 in the same range as monocytes from the circuit by 2 ... 19). The decrease in circulating monocytes was concordant with the number of monocytes subsequently recovered. This decrease ... 22 illustrates percent monocytes positive for TF during SECC. TF reported by a TF MAb cocktail (black bars) or free TF ...https://patents.google.com/patent/US5437864?oq=flatulence
Effect of isoflurane on monocyte adhesion molecule expression in ...: Ingenta Connect
Recruitment of monocytes to inflamed tissue is a crucial step in the acute inflammatory reaction. Adherence of monocytes to ... Since PSGL-1 is important during the initial step of monocyte adhesion to endothelial P-selectin, the decrease in monocyte ... In the present study, we determined the effect of isoflurane on monocyte adhesion receptor expression in vitro. Methods: ... At both concentrations, the FMLP-induced removal of PSGL-1 from the monocyte surface was increased. Furthermore, at 1 MAC ...http://www.ingentaconnect.com/content/mksg/aas/2003/00000047/00000005/art00010