*  Endothelial Function in Deoxycorticosterone-NaCl Hypertension | Circulation
... prostacyclin acts via adenylate cyclase and cAMP, and EDHF dilates arteries via the opening of K+ channels.15 24 Impaired ... Subsequently, NO stimulates soluble guanylate cyclase, elevating intracellular cGMP in smooth muscle; ...
  http://circ.ahajournals.org/content/93/5/1000
*  ADP-Ribosyltransferase, NAD-Agmatine - Medical Dictionary online-medical-dictionary.org
... such as activation of Adenylate Cyclase, Regulation of protein synthesis at the level of Elongation Factor 2, and Ion Transport ...
  http://www.online-medical-dictionary.org/definitions-a/adp-ribosyltransferase-nad-agmatine.html
*  Canine Cardiac Muscarinic Receptors, G Proteins, and Adenylate Cyclase after Long-Term Morphine | Journal of Pharmacology and...
Adenylate Cyclase Activity.. Basal, MnCl2-stimulated, and maximal (MnCl2 plus forskolin) adenylate cyclase activity were ... receptor/G protein coupling to adenylate cyclase. Adenylate cyclase activity was decreased by an average of 36% in the left ... Maximal muscarinic and β-adrenergic receptor/G protein coupling to adenylate cyclase were examined by determining the cyclase ... To determine whether morphine treatment altered the adenylate cyclase available for stimulation, cyclase activity was measured ...
  http://jpet.aspetjournals.org/content/291/2/725
*  5-hydroxytryptamine release into human jejunum by cholera toxin. | Gut
BACKGROUND: Cholera toxin produces intestinal secretion by activation of the adenylate cyclase complex. However animal studies ...
  http://gut.bmj.com/content/39/4/528
*  Sequence Detail
adenylate cyclase 4. 24. 7. 7. 5. Sequence references in MGI J:90438 Mouse Genome Informatics Scientific Curators, Obtaining ...
  http://www.informatics.jax.org/sequence/104110
*  Sequence Detail
Adenylate cyclase type IV;AltName: Full=Adenylyl cyclase 4; ... RecName: Full=Adenylate cyclase type 4; EC=4.6.1.1 {ECO:0000250 ...
  http://www.informatics.jax.org/sequence/Q91WF3
*  A - Genes - Genetics Home Reference - NIH
ADCY5: adenylate cyclase 5. *ADGRE2: adhesion G protein-coupled receptor E2. *ADGRG1: adhesion G protein-coupled receptor G1 ...
  https://ghr.nlm.nih.gov/gene
*  Plus it
The effects may result from activation of an unknown membrane receptor and the adenylate cyclase/cAMP pathway, which enhances ... It is well established that β-adrenergic stimulation activates the adenylate cyclase (AC), leading to an increased cyclic AMP ( ... Evidence for close coupling of β-1 and β-2 adrenergic receptors to adenylate cyclase. J Pharmacol Exp Ther 238:886-892. ...
  http://jpet.aspetjournals.org/content/293/2/592
*  ADCY8 - Wikipedia
"Entrez Gene: ADCY8 adenylate cyclase 8 (brain)". Human ADCY3 genome location and ADCY3 gene details page in the UCSC Genome ... Barcova M, Speth C, Kacani L, Uberall F, Stoiber H, Dierich MP (Mar 1999). "Involvement of adenylate cyclase and p70(S6)-kinase ... Adenylyl cyclase type 8 is an enzyme that in humans is encoded by the ADCY8 gene. Adenylyl cyclase is a membrane bound enzyme ... Parma J, Stengel D, Gannage MH, Poyard M, Barouki R, Hanoune J (Aug 1991). "Sequence of a human brain adenylyl cyclase partial ...
  https://en.wikipedia.org/wiki/ADCY8
*  3C15: Complex Of Gs-Alpha With The Catalytic Domains Of Mammalian Adenylyl Cyclase: Complex With Pyrophosphate And Mg
ADENYLATE CYCLASE TYPE 2ADENYLATE CYCLASE TYPE 5GUANINE NUCLEOTIDE-BINDING PROTEIN G(S) SUBUNIT ALPHA ISOFORMS SHORT5'- ... Adenylate Cyclase Type 2(Gene symbol: Adcy2). C. 1. Guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short(Gene ... 3C15: Complex Of Gs-Alpha With The Catalytic Domains Of Mammalian Adenylyl Cyclase: Complex With Pyrophosphate And Mg. ...
  https://www.ncbi.nlm.nih.gov/Structure/pdb/3C15
*  Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI
Guanine nucleotide-binding protein G(i) subunit alpha-1; Adenylate cyclase-inhibiting G alpha protein. ... Guanine nucleotide-binding protein G(i) subunit alpha-1; Adenylate cyclase-inhibiting G alpha protein. ... Guanine nucleotide-binding protein G(i) subunit alpha-1; Adenylate cyclase-inhibiting G alpha protein. ... Guanine nucleotide-binding protein G(i) subunit alpha-1; Adenylate cyclase-inhibiting G alpha protein. ...
  https://www.ncbi.nlm.nih.gov/pcassay?LinkName=pcassay_pcassay_targetneighbor_list&from_uid=255377
*  VPAC1-targeted PET/CT scan: improved molecular imaging for the diagnosis of prostate cancer using a novel cell surface antigen ...
... and pituitary adenylate cyclase activating peptide (PACAP) receptor specific peptide analogues for PET imaging of breast cancer ... Vasoactive intestinal peptide/pituitary adenylate cyclase-activating peptide receptor subtypes in human tumors and their ...
  https://link.springer.com/article/10.1007/s00345-018-2263-1
*  The Controversial Role of Microglia in Malignant Gliomas
M. Delgado, J. Leceta, and D. Ganea, "Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide ...
  https://www.hindawi.com/journals/jir/2013/285246/
*  To Evaluate the Blockade of CGRP in Preventing PACAP-38 Induced Migraine-like Attacks With AMG 334 in Migraine Patients - Full...
Pituitary Adenylate Cyclase-Activating Polypeptide. Growth Substances. Physiological Effects of Drugs. Vasodilator Agents. ...
  https://clinicaltrials.gov/ct2/show/NCT02542605
*  GNAI2 - Guanine nucleotide-binding protein G(i) subunit alpha-2 - Homo sapiens (Human) - GNAI2 gene & protein
... they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division. ... The G(i) proteins are involved in hormonal regulation of adenylate cyclase: ... The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- ... negative regulation of adenylate cyclase activity Source: ProtInc ,p>Traceable Author Statement,/p> ,p>Used for information ...
  http://www.uniprot.org/uniprot/P04899
*  Gene Ontology Classifications
adenylate cyclase 7. MGI:102891 Go Annotations as Summary Text (Tabular View) (GO Graph). Summary from NCBI RefSeq. [Summary is ... This summary is for the human ortholog.] This gene encodes a membrane-bound adenylate cyclase that catalyses the formation of ... The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by ...
  http://www.informatics.jax.org/go/marker/MGI:102891
*  VIBHAR 05599 - Uncharacterized protein - Vibrio campbellii (strain ATCC BAA-1116 / BB120) - VIBHAR 05599 gene & protein
Cluster: Adenylate cyclase 2. 32. Full view. Protein. Similar proteins. Organisms. Length. Cluster ID. Cluster name. Size. ...
  http://www.uniprot.org/uniprot/A7N457
*  Gene Expression Literature Detail
adenylate cyclase 3. MGI:99675 Reference. J:171417 Henion TR, Faden AA, Knott TK, Schwarting GA, {beta}3GnT2 Maintains Adenylyl ... Cyclase-3 Signaling and Axon Guidance Molecule Expression in the Olfactory Epithelium. J Neurosci. 2011 Apr 27;31(17):6576-86 ...
  http://www.informatics.jax.org/gxdlit/key/125490
*  KEGG BRITE: KEGG Orthology (KO) - Camelus ferus (Wild Bactrian camel)
102510993 ADCY2; adenylate cyclase 2 102508985 PRKACA; protein kinase cAMP-activated catalytic subunit alpha 102506255 PRKACB; ... adenylate cyclase 2 [EC:4.6.1.1] K04345 PKA; protein kinase A [EC:2.7.11.11] K04345 PKA; protein kinase A [EC:2.7.11.11] K05870 ...
  http://www.genome.jp/kegg-bin/get_htext?cfr00001+102511249
*  KEGG BRITE: KEGG Orthology (KO) - Tupaia chinensis (Chinese tree shrew)
... adenylate cyclase 1 102492353 ADCY2; adenylate cyclase 2 102477532 ADCY3; adenylate cyclase 3 102490273 ADCY4; adenylate ... adenylate cyclase 5 102468478 ADCY6; adenylate cyclase 6 102496578 ADCY7; adenylate cyclase 7 102472317 ADCY8; adenylate ... adenylate cyclase 1 [EC:4.6.1.1] K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1] K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1] ... adenylate cyclase 4 [EC:4.6.1.1] K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1] K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1] ...
  http://www.genome.jp/kegg-bin/get_htext?tup00001+102491327
*  Is the attenuation of beta-adrenergic agonist efficacy during labor caused by elevated prostaglandin E levels?
Adenylate Cyclase / metabolism. Adrenergic beta-Agonists / pharmacology*. Cyclic AMP / metabolism. Dinoprostone / pharmacology ... active labor exhibited a significant attenuation of beta-adrenergic receptor function as a result of reduced adenylyl cyclase ...
  http://www.biomedsearch.com/nih/attenuation-beta-adrenergic-agonist-efficacy/9822495.html
*  KEGG ORTHOLOGY: K08048
K08048 ADCY8; adenylate cyclase 8. Human Diseases. Cancers. 05200 Pathways in cancer. K08048 ADCY8; adenylate cyclase 8. ... K08048 ADCY8; adenylate cyclase 8. 04024 cAMP signaling pathway. K08048 ADCY8; adenylate cyclase 8. 04022 cGMP - PKG signaling ... K08048 ADCY8; adenylate cyclase 8. 04923 Regulation of lipolysis in adipocyte. K08048 ADCY8; adenylate cyclase 8. 04912 GnRH ... K08048 ADCY8; adenylate cyclase 8. Infectious diseases. 05166 HTLV-I infection. K08048 ADCY8; adenylate cyclase 8. Drug ...
  http://www.genome.jp/dbget-bin/www_bget?ko:K08048
*  Role of cAMP Response Element Binding Protein in Cardiovascular Remodeling | Arteriosclerosis, Thrombosis, and Vascular Biology
However, in the late response, the adenylate cyclase/cAMP pathway activated PKA. Despite these findings, it is not yet clear ...
  http://atvb.ahajournals.org/content/26/3/449
*  KEGG BRITE: KEGG Orthology (KO) - Equus caballus (horse)
100071337 ADCY2; adenylate cyclase 2 100052828 PRKACB; protein kinase cAMP-activated catalytic subunit beta 100064302 PRKACA; ... adenylate cyclase 2 [EC:4.6.1.1] K04345 PKA; protein kinase A [EC:2.7.11.11] K04345 PKA; protein kinase A [EC:2.7.11.11] K05870 ...
  http://www.genome.jp/kegg-bin/get_htext?ecb00001+100054723
*  KEGG BRITE: KEGG Orthology (KO) - Cricetulus griseus (Chinese hamster)
... adenylate cyclase 5 100768368 Adcy6; adenylate cyclase 6 100756132 Adcy7; adenylate cyclase 7 103162985 adenylate cyclase type ... adenylate cyclase 5 100768368 Adcy6; adenylate cyclase 6 100756132 Adcy7; adenylate cyclase 7 103162985 adenylate cyclase type ... adenylate cyclase 1 100773811 Adcy2; adenylate cyclase 2 100770498 Adcy3; adenylate cyclase 3 100768998 Adcy4; adenylate ... adenylate cyclase 1 100773811 Adcy2; adenylate cyclase 2 100770498 Adcy3; adenylate cyclase 3 100768998 Adcy4; adenylate ...
  http://www.genome.jp/kegg-bin/get_htext?cge00001+100774486