Loading...


*  Head and neck cancer - Wikipedia
Smokeless tobacco is cause of oral and pharyngeal cancers (oropharyngeal cancer). Cigar smoking is an important risk factor for ... Immunotherapy with immune checkpoint inhibitors is being investigated in head and neck cancers. "Head and Neck Cancers". NCI. ... Adenocarcinoma is a cancer of epithelial tissue that has glandular characteristics. Several head and neck cancers are ... The stage at which the cancer is diagnosed is also a critical factor in the prognosis of throat cancer. Treatment guidelines ...
  https://en.wikipedia.org/wiki/Head_and_neck_cancer
*  Methods for detecting and treating cancer - The General Hospital Corporation
... and glandular cancers (or adenocarcinoma). Both squamous cancers and glandular cancers have clinically and/or histologically ... Persistent infection with high risk HPV (Types 16 and 18) has been shown to be an important risk factor for malignant ... Tumor infiltrating T cells contribute to immune control of this tumor. However the tumor dysregulates the immune response to ... In another aspect, the invention generally features a method of determining the prognosis of a subject diagnosed as having ...
  http://www.freepatentsonline.com/9885720.html
*  Signet ring cell carcinoma - Wikipedia
The role of other risk factors in gastric cancer such as salt-preserved food, smoking, auto-immune gastritis are not well ... Stomach cancers with both adenocarcinoma and some SRC (known as mixed-SRCC) exhibit more aggressive behavior than purely SRCC ... In advanced gastric cancers, the prognosis for patients with the SRCCs was significantly worse than for the other histological ... SRCC cancers are usually diagnosed during the late stages of the disease, so the tumors generally spread more aggressively than ...
  https://en.wikipedia.org/wiki/Signet_ring_cell_carcinoma
*  Cancers | Free Full-Text | The Endometriotic Tumor Microenvironment in Ovarian Cancer | HTML
An important clinical caveat to the association of endometriosis with ovarian cancer is the improved prognosis for women with ... The unique tumor microenvironment of endometriosis is composed of epithelial, stromal, and immune cells, which adapt to survive ... and available model systems for endometriosis-associated ovarian cancers. Continued research on these unique ovarian cancers ... Additionally, how the presence of endometriosis improves prognosis is also undefined, but likely relies on the endometriotic ...
  https://www.mdpi.com/2072-6694/10/8/261/htm
*  Patent US6984508 - Biological compositions and methods for treatment of cervical cancer - Google Patents
5:121-135). Other risk factors include tobacco use, DES (diethylstilbestro) use during pregnancy, long term use (more than 10 ... Stage I cancers are small, localized and usually curable. Stage II and III cancers typically are locally advanced and/or have ... It is used to assess a patient's prognosis and to determine the choice of therapy. The stage of a cancer is determined by the ... Method for immune system activation by administration of a β(1-3) glucan which is produced by Saccharomyces cerevisiae strain ...
  http://www.google.co.uk/patents/US6984508
*  Biliary Disease: Background, Pathophysiology, Etiology
Cholangiocarcinoma is an adenocarcinoma of the bile ducts. [9] It may occur without associated risk factors, but it is ... Prognosis. In primary sclerosing cholangitis (PSC), several factors suggest a high risk of death. These include advancing age, ... It represents 54% of biliary tract cancers, and more than 6500 patients die from this disease in the United States each year. ... 8] Circulating immune complexes also have been identified but are unlikely to play a pathogenic role. Circulating T lymphocyte ...
  https://emedicine.medscape.com/article/171386-overview
*  Translational Therapeutic Opportunities in Ductal Adenocarcinoma of the Pancreas | Clinical Cancer Research
Approximately 10% of cases have a hereditary cause; another major risk factor is familial pancreatitis (2). The prognosis of ... Like other cancers, PDA cells rely on fuel sources for homeostasis and proliferation; as such, interrupting the use of 2 major ... Because CD40 activation can reverse immune suppression and drive antitumor T-cell responses, clinical studies have tested the ... Upon activation by growth factors such as TGF-β1, platelet-derived growth factor (PDGF), and fibroblast growth factor (FGF), ...
  http://clincancerres.aacrjournals.org/content/18/16/4249.long
*  Women's Cancer Center: Cervical Cancer
Womens Cancer Center site with information on latest treatment of gynecological cancers,including reproductive organs,ovaries, ... the risk factors, screening, common signs and symptoms, how it is diagnosed and staged, and a treatment overview. ... RISK FACTORS. The average age of women with invasive cervical cancer in the United States is between 45 and 50, while the ... Suppression of the immune system from corticosteroids, kidney transplants, therapy for other cancers, or HIV. *A history of ...
  http://www.womenscancercenter.com/info/types/cervix.html
*  Role of Nampt and Visceral Adiposity in Esophagogastric Junction Adenocarcinoma
... immune pathology, immunodeficiency, autoimmune diseases, immune disorders, and immunotherapy. ... "Role of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma," British Journal of Surgery ... I. Vucenik and J. P. Stains, "Obesity and cancer risk: evidence, mechanisms, and recommendations," Annals of the New York ... eNampt may promote tumor progression in a large number of cancers including breast cancer [24, 25] and prostate cancer [26]. ...
  https://www.hindawi.com/journals/jir/2017/3970605/
*  Cancer-associated fibroblast - Wikipedia
Being female in this study also proved to be a bigger risk factor, with men being protected more against the effects. Cancer- ... of podoplanin in CAFs has been found to play a fundamental role in worsening the prognosis of patients with lung adenocarcinoma ... They do this through a number of different mechanisms, notably angiogenesis, metastasis and immune evasion. CAF express various ... Cancers. 7 (4): 2443-2458. doi:10.3390/cancers7040902. Sappino, A.-P.; Skalli, O.; Jackson, B.; Schürch, W.; Gabbiani, G. (1988 ...
  https://en.wikipedia.org/wiki/Cancer-associated_fibroblast
*  LC3B globular structures correlate with survival in esophageal adenocarcinoma | BMC Cancer | Full Text
Cox regression was used to examine association with clinical risk factors. A distinct globular pattern of LC3B expression was ... Prognosis remains poor with overall five-year survival rates under 25 %. Only a limited number of patients benefit from ... Esophageal adenocarcinoma tumor tissue from two independent sites, was examined retrospectively. Tumors from 104 neoadjuvant ... Multivariate analysis found that this was a strong independent predictor of poor prognosis (p < 0.001). This distinctive ...
  https://bmccancer.biomedcentral.com/articles/10.1186/s12885-015-1574-5
*  https://www.medicalnewstoday.com/articles/319477.php
Causes and risk factors. *Prognosis. *Treatment options. *Outlook. What is papillary urothelial carcinoma?. Papillary ... adenocarcinoma. *squamous cell carcinoma. *urothelial carcinoma. There are many other rare bladder cancers besides these three ... Chemotherapy has numerous side effects, including fatigue, nausea, and a weakened immune system. These side effects may make ... the prognosis for people diagnosed with papillary urothelial carcinoma depends on many different factors. Some of the factors ...
  https://www.medicalnewstoday.com/articles/319477.php
*  Dictionary - pathology overview - The Human Protein Atlas
Many factors are known to increase the risk of cancer, including tobacco use, certain infections, radiation, obesity and ... Epithelial tumors are the most common forms of cancer and include adenocarcinoma, representing tumors originating from ... and avoiding immune destruction, which allows cancer cells to evade immunological destruction (fig.1). As stated above, the ... the corresponding normal phenotype and has in general a relative low malignancy grade whereas in poorly differentiated cancers ...
  http://www.proteinatlas.org/learn/dictionary/pathology
*  Current Research Projects - School of Medicine - Trinity College Dublin
... thromboxane synthase has been implicated as a survival factor in many cancers, and has been associated with a poor prognosis. ... including oesophageal and colorectal adenocarcinoma. Visceral adiposity, in particular, is a major risk factor for the ... We want to see whether insulin-like growth factors are produced by immune cells found in tumours. ... A major risk factor for the development of Barrett's oesophagus, is obesity. Central obesity (the build up of fatty on the ...
  http://www.tcd.ie/medicine/surgery/research/projects/
*  Management of metastatic breast cancer | Oncology Practice
Pancreatic adenocarcinoma: Staging, radiographic & laboratory evaluation. Take Quiz. Heritable risk factors for pancreatic ... Immune checkpoints & their inhibitors. Take Quiz. Immune checkpoint inhibitors & tumors with mismatch repair deficiency. Take ... Metastatic breast cancer: Prognosis. Take Quiz. Management of metastatic breast cancer in pre- and post-menopausal patients ... Risk factors & screening for gastric cancers. Take Quiz. Risk factors associated with PDA. Take Quiz. ...
  https://mdedge.com/oncologypractice/quiz/5587/breast-cancer/management-metastatic-breast-cancer?channel=192
*  Cancer therapies: Vaccine adjuvants, Part 2 | Oncology Practice
Pancreatic adenocarcinoma: Staging, radiographic & laboratory evaluation. Take Quiz. Heritable risk factors for pancreatic ... Immune checkpoints & their inhibitors. Take Quiz. Immune checkpoint inhibitors & tumors with mismatch repair deficiency. Take ... Metastatic breast cancer: Prognosis. Take Quiz. Management of metastatic breast cancer in pre- and post-menopausal patients ... Risk factors & screening for gastric cancers. Take Quiz. Risk factors associated with PDA. Take Quiz. ...
  https://mdedge.com/oncologypractice/quiz/4025/immunotherapy/cancer-therapies-vaccine-adjuvants-part-2?channel=232
*  Bladder Cancer Pictures: Warning Signs, Treatments, Survival Rates
See the warning signs, causes, treatments, and prognosis for bladder cancer. ... Other Risk Factors. Anyone can get bladder cancer, but these factors put you at greater risk:. *Gender: Men are three times ... makes it easier for the immune system to overcome the defenses of cancer cells. These drugs are primarily for advanced cancers ... Squamous cell carcinoma and adenocarcinoma are much less common. Swipe to advance ...
  https://www.webmd.com/cancer/bladder-cancer/ss/slideshow-bladder-cancer-overview
*  Vulvar Cancer - Women's Health Issues - Merck Manuals Consumer Version
... treatment of Cancers of the Female Reproductive System from the Home Version of the Merck Manuals. ... include adenocarcinomas (which develop from gland cells), basal cell carcinomas (which rarely spread), and rare cancers such as ... Risk Factors. The risk of developing vulvar cancer is increased by the following:. ... Prognosis. If vulvar cancer is detected and treated early, about 3 of 4 women have no sign of cancer 5 years after diagnosis. ...
  http://www.merckmanuals.com/home/women-s-health-issues/cancers-of-the-female-reproductive-system/vulvar-cancer
*  Tumour DNA in blood may serve as prognostic marker of pancreatic cancer. ecancer - News
The incidence of pancreatic adenocarcinoma is on the rise in Western countries, and prognosis remains very poor. ... LATEST News: Putting melanoma to sleep News: New immune system regulator discovered News: New staining method enables nano-CT ... Cancer risk associated with key epigenetic changes occurring through normal ageing process (23 Feb 2018) ... Our results demonstrate the utility of circulating biomarkers in subclassifying cancers and managing treatment,' Bachet noted ...
  http://ecancer.org/news/10726-tumour-dna-in-blood-may-serve-as-prognostic-marker-of-pancreatic-cancer.php
*  Plus it
It has been observed that smoking, a risk factor for many diseases, increases the risk of developing PDACs with a factor of ... as well as other types of cancers, such as breast cancer, gastric adenocarcinoma, and glioblastoma multiforme (17, 18, 22, 25 ... Pancreatic cancer has a dismal prognosis mostly due to an advanced stage at the time of diagnosis. One way to improve prognosis ... The identified serum immune signatures could be considered snapshots of the immunologic activity in a patient at the time of ...
  http://cancerres.aacrjournals.org/content/72/10/2481
*  Sarcoma & GIST pathophysiology | Oncology Practice
Pancreatic adenocarcinoma: Staging, radiographic & laboratory evaluation. Take Quiz. Heritable risk factors for pancreatic ... Immune checkpoints & their inhibitors. Take Quiz. Immune checkpoint inhibitors & tumors with mismatch repair deficiency. Take ... Metastatic breast cancer: Prognosis. Take Quiz. Management of metastatic breast cancer in pre- and post-menopausal patients ... Sarcomas represent more than 5% of all cancers in the United States ...
  https://mdedge.com/oncologypractice/quiz/5527/sarcoma-gist/sarcoma-gist-pathophysiology?channel=292
*  direct link to this comment
Causes and risk factors. The presence of human papilloma virus infection (HPV), especially in male homosexuals are at a high ... Adenocarcinomas, which are not common behave like rectal cancers and have higher incidence of recurrence and metastasis. These ... Immune suppression. Kidney transplant patients are associated with a 100-fold increase in anogenital cancers. ... When balanced with other factors, the prognosis for patients with squamous cell carcinoma of the anus and for those with ...
  https://www.doctorslounge.com/index.php/reference/diseases/90
*  Bacteria and cancer: cause, coincidence or cure? A review | Journal of Translational Medicine | Full Text
... colon and bladder cancers. Thus bacterial species and their roles in particular cancers appear to differ among different ... This critical factor may lead to the development of non-invasive diagnostic tests, innovative treatments and cancer vaccines. ... In contrast, exposure to H. pylori appears to reduce the risk of esophageal cancer in others. Salmonella typhi infection has ... prevention or treatment of cancers. The complex relationship between bacteria and humans is demonstrated by Helicobacter pylori ...
  https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-4-14
*  Plus it
... correlation with important high-risk prognostic factors. Neoplasia 2006;8:190-8. ... PD-L1 may play an important role in the immune evasion from host immune system in cancer patients. On the other hand, some ... Tumor B7-1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up. Cancer Res 2006;66:3381 ... Pancreatic cancer is among the most lethal cancers due, in part, to a lack of effective therapies (1, 2). To improve the ...
  http://clincancerres.aacrjournals.org/content/13/7/2151
*  The Tohoku Journal of Experimental Medicine
... this study aimed to identify caries-related risk factors and develop a simplified risk prediction model for dental caries. Risk ... PINK1 Expression Is Associated with Poor Prognosis in Lung Adenocarcinoma.. In conclusion, high PINK1 expression is correlated ... Therefore, we surveyed sera from septic patients for factors that suppress the innate immune response to DAMPs, including ... eg.(cancer,cancers)(cervical,cervix)!("Squamous cell carcinoma",SCC). will return records where either the words 'cancer' or ' ...
  https://medworm.com/journal/the-tohoku-journal-of-experimental-medicine/