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*  Nucleoside-phosphate kinase - Wikipedia
Byeon, L.; Shi, Z.; Tsai, M.D. (1995). "Mechanism of adenylate kinase. The "essential lysine" helps to orient the phosphates ... and other molecular motor proteins G protein and other proteins involved in signal transduction Helicases for unwinding DNA and ... binding by holding the ATP molecule in a position allowing for specific binding to the active site and by providing additional ... "Ancient Divergence of long and short isoforms of adenylate kinase molecular evolution of the nucleoside monophosphate kinase ...
  https://en.wikipedia.org/wiki/Nucleoside-phosphate_kinase
*  Extracellular Signal-Regulated Kinase - Drug Resistance to EGFR Inhibitors in Lung Cancer
Lammens and Hopfner (21) solved the crystal structure of the ABC-NBD of the SMC protein in complex with the adenylate kinase ... and γ-phosphates of Ap5A destined the canonical Mg2+-ATP-binding site on lobe I from the SMC NBD. The additional adenosine the ... adenylate kinase activity is coupled to channel function (18). Adenylate kinases are enzymes that bind ATP and AMP at separate ... detect adenylate kinase activity as well as the authors figured Ataluren CFTR can be an ATPase however not an adenylate kinase ...
  http://elevateblogconference.com/category/extracellular-signal-regulated-kinase/
*  Nucleic acid metabolism - Wikipedia
AMP and GMP can then be converted into ATP and GTP, respectively, by kinases that add additional phosphates. ATP stimulates ... Adenylate kinase is a specific nucleoside-monophosphate kinase that functions only on adenosine-monophosphate. Nucleic acid RNA ... DNA Carbohydrate metabolism Protein metabolism Voet, Donald; Voet, Judith; Pratt, Charlotte (2008). Fundamentals of ... Once the nucleotides are synthesized they can exchange phosphates among one another in order to create mono-, di-, and tri- ...
  https://en.wikipedia.org/wiki/Nucleic_acid_metabolism
*  Metabolic suppression during protracted exposure to hypoxia in the jumbo squid, Dosidicus gigas, living in an oxygen minimum...
eukaryotic elongation factor 2 kinase. eEF2. eukaryotic elongation factor 2. GSH. glutathione. HSP. heat shock protein. M. body ... For juvenile squid, adenylate analysis was done with a high performance liquid chromatographic method similar to that reported ... 2A,B). Arg-P levels in juveniles declined by an additional 50% over the next few hours while adult levels remained constant ... arginine phosphates) had been converted to arginine via acid hydrolysis (Arg-P=Σarginine-arginine). Arginine is reductively ...
  http://jeb.biologists.org/content/217/14/2555
*  LHL.net Don'ts.html
... by release of cytosolic adenylate kinase measuring membrane damage. Glyphosate formulations induce apoptosis , cell suicide , ... 6. GM crops are not about feeding the poor. Additional to control over needed food, they are about supplying the developed ... However, changing plant protein may alter these chemicals, increase plant toxins and/or reduce its phytonutrients. For example ... Acid Phosphatase which contributes to uptake of phosphates was reduced by 26.6%. Nitrogenase enzymes which help fix nitrogen ...
  https://longerhealthylife.net/Don%27ts.html
*  PPT - Metabolism 10/27/09 PowerPoint Presentation - ID:3351756
3. Adenylate kinase reaction AMP + ATP 2ADP. About 1.5 kg of ATP turnover per hour for the average person (about 3 moles) ... In the separated phosphates, there is no competition so the resonance is better. ... insulin causes an ___________in protein synthesis; while glucagon causes an __________. answer. increase : decrease back. ... 4. Additional phosphoanhydride cleavage in highly endergonic reactions.. Formation of ATP. 1. Substrate level phosphorylation ...
  https://www.slideserve.com/lahela/metabolism-10-27-09
*  Interaction among Skeletal Muscle Metabolic Energy Systems during Intense Exercise
The creatine kinase and adenylate kinase reactions both produce ATP, yet the creatine kinase reaction has by far the greater ... Intense exercise also increases amino acid oxidation, but involves negligible protein catabolism due to the short-term nature ... Phase 1 involves six carbon phosphorylated carbohydrate intermediates called hexose phosphates. Phase 1 is also ATP costly, ... production from glycogenolysis and increased glucose uptake provides a rapid source of fuel for a sequence of 8 additional ...
  https://www.hindawi.com/journals/jnme/2010/905612/
*  Signaling Pathways Modulated by Dopamine Receptors | Springer for Research & Development
Haycock, J. W., Ahn, N. G., Cobb, M. H., and Krebs, E. G. (1992) ERK1 and ERK2, two microtubule-associated protein 2 kinases, ... Limbird, L. (1988) Receptors linked to inhibition of adenylate cyclase: additional signalling mechanisms. FASEB J. 2, 2686-2695 ... Undie, A. S. and Friedman, E. (1990) Stimulation of a dopamine D1 receptor enhances inositol phosphates formation in rat brain ... Huff, R. M. and Lajiness, M. E. (1994) D2 dopamine receptors stimulate mitogen activated protein kinases. J. Cell. Biochem 18B ...
  https://rd.springer.com/chapter/10.1007/978-1-4757-2635-0_6
*  Detecting Enzymes That Metabolize Phosphates and Polyphosphates-Section 10.3 | Thermo Fisher Scientific - AR
Probes for Protein Kinases, Protein Phosphatases and Nucleotide-Binding Proteins-Section 17.3). As with other fluorescent ... The PiPer Kit is more sensitive and better suited for high-throughput studies in microplates, but requires an additional ... adenylate cyclase and S-acetyl coenzyme A synthetase. In the PiPer pyrophosphate assay, inorganic pyrophosphatase hydrolyzes PP ... Use of natural substrates. The Antibody Beacon tyrosine kinase assay utilizes unlabeled peptide or protein substrates, is ...
  https://www.thermofisher.com/ar/es/home/references/molecular-probes-the-handbook/enzyme-substrates/detecting-enzymes-that-metabolize-phosphates-and-polyphosphates.html
*  IJMS | Free Full-Text | A Dual Role of Strigolactones in Phosphate Acquisition and Utilization in Plants | HTML
Fe and Al phosphates, or is converted to organic phosphates (e.g., phytic acid) that are not immediately available for plants [ ... Woo, H.R.; Chung, K.M.; Park, J.H.; Oh, S.A.; Ahn, T.; Hong, S.H.; Jang, S.K.; Nam, H.G. ORE9, an F-box protein that regulates ... Duff, S.M.G.; Moorhead, G.B.G.; Lefebvre, D.D.; Plaxton, W.C. Phosphate starvation inducible bypasses of adenylate and ... These findings suggested that SLs are not the only limiting factor for mycorrhizal colonization which may require additional ...
  http://www.mdpi.com/1422-0067/14/4/7681/htm
*  Construction and evolution of an Escherichia coli strain relying on nonoxidative glycolysis for sugar catabolism | PNAS
... cAMP receptor protein; cyaA, adenylate cyclase; DHAP, dihydroxyacetone phosphate; E4P, erythrose 4-phosphate; ED, Entner- ... resulting in the loss of pyruvate kinase F, one of the pyruvate kinase genes. This deletion may facilitate the flux in the ... 3B). Therefore, we transformed the NOG6/pPL274 strain with an additional plasmid (pTW371) for expressing two tkt genes (WP_ ... 7) designed a synthetic pathway termed nonoxidative glycolysis (NOG), which uses Xpk-dependent cleavage of sugar phosphates and ...
  http://www.pnas.org/content/115/14/3538
*  Regulation of Cyclin-Dependent Kinase 5 and Calcium/Calmodulin-Dependent Protein Kinase II by Phosphatidylinositol-Linked...
Thus, our results reveal additional mechanisms for dopamine receptor-regulated DARPP-32/protein phosphatase 1 pathway in brain ... Undie AS and Friedman E (1990) Stimulation of a dopamine D1 receptor enhances inositol phosphates formation in rat brain. J ... stimulates phospholipase-C activity independent of adenylate cyclase. J Pharmacol Exp Ther 248: 171-175. ... protein kinase A; PLCβ, phospholipase Cβ; cdk5, cyclin-dependent kinase 5; CaMK II, calcium/calmodulin-dependent protein kinase ...
  http://molpharm.aspetjournals.org/content/66/6/1500
*  Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases | BMC...
Lienhard GE, Secemski II: P1,P5-Di(adenosine-5')pentaphosphate, a potent multisubstrate inhibitor of adenylate kinase. J. Biol ... members of the histidine triad protein family such as the FHIT tumour suppresser protein and (in lower eukaryotes) the related ... In particular, they both possess the additional Gln residue (Q86 in DIPP-2β) that distinguishes hDIPP-2β from hDIPP-2α and ... Previously, the human DIPP family comprised hDIPP-1, a ubiquitous enzyme able to hydrolyse both inositol phosphates and ...
  https://bmcbiochem.biomedcentral.com/articles/10.1186/1471-2091-3-20
*  Patent US6492130 - Modulation of the sulfonylurea receptor and calcium in adipocytes for ... - Google Patents
These effects were attributed to sulfonylurea-induced inhibition of cAMP level and protein kinase A activity. Thus, rodent ... and relatively minor amounts of citrates or phosphates. The ordinary skilled person would know of additional agents that are ... an adenylate cyclase activator, induced a 48% increase in lipolysis in human adipocytes (p,0.05); this effect was reversed by ... mg of protein. Protein was determined by the modified method of Lowry using bovine serum albumin as a standard. All data were ...
  http://www.google.com/patents/US6492130?dq=6,123,819
*  Antioxidants
... as no medically authorized kinase inhibitor is definitely selective for Src over additional SFKs or Abl kinase (Davis et al., ... Adenylate kinases (AKs) represent a set of enzymes that catalyze a reversible high-energy phosphoryl transfer reaction between ... Then protein-protein interaction network and literature information are utilized to find genes that are relevant to the ... and the buy 131189-57-6 non-oxidative PPP that recycles pentose phosphates to glycolytic intermediates or generates de novo ...
  http://www.brain-tumor-cancer-information.com/category/antioxidants/
*  Plus it
... with creatine kinase (CK) linking ATP generation to KATP channel closure and adenylate kinase (AK) regulating KATP channel ... UCP, uncoupling protein. The ATP-sensitive K+ channel (KATP channel) activity plays a crucial role in glucose-stimulated ... Their activity may be further modulated by additional factors that regulate the levels of nucleotides in the immediate ... Schulze D, Rapedius M, Krauter T, Baukrowitz T: Long-chain acyl-CoA esters and phosphatidylinositol phosphates modulate ATP ...
  http://diabetes.diabetesjournals.org/content/53/suppl_3/S113
*  METHOD FOR TREATING OR PREVENTING CONDITIONS BY ELEVATION OF THE ADENOSINE LEVEL IN AN INDIVIDUAL - Patent application
A combined administration of recombinant CD73 protein or a cytokine or both, with AMP and such an adenylate kinase inhibitor ... additional details respecting the practice, are incorporated by reference. [0004]The interaction between lymphocytes and ... such as phosphates and/or other pharmaceutically acceptable excipients. The active ingredient, e.g. the cytokines or other ... 11. The method according to claim 5 wherein an adenylate kinase inhibitor, which prevents AMP from conversion into adenosine ...
  http://www.patentsencyclopedia.com/app/20090269303
*  Phosphite-Mediated Suppression of Anthocyanin Accumulation Regulated by Mitochondrial ATP Synthesis and Sugars in Arabidopsis,...
Quantitative phosphoproteomics of protein kinase SnRK1 regulated protein phosphorylation in Arabidopsis under submergence . J. ... To segregate potential additional T-DNA insertion loci, we backcrossed the phi1 mutant to WT plants. All F1 progeny showed the ... of adenylate and phosphate dependent glycolytic enzymes in Brassica nigra suspension cells . Plant Physiol . 90 : 1275 - 1278 ... but reduced abundance of hexose phosphates, and their amounts are restored upon Pi replenishment (Pant et al. 2015). The ...
  https://www.deepdyve.com/lp/ou_press/phosphite-mediated-suppression-of-anthocyanin-accumulation-regulated-5ybgJsRkfl
*  The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance | SpringerLink
... protein kinase C, ERKs, phosphatidylinositol 3-kinases (PI3K), MAP kinases (MAPK) and Rho [6, 7, 8]. The situation concerning ... adenylate kinase, nucleoside diphosphate kinase, and potentially ecto-F1-Fo ATP synthases [21, 22, 23, 24, 25] that may ... ATP is released by CD4+ and CD8+ T cells upon stimulation with Con A or anti-CD3 mAb while CD39 functions as an additional ... They also contribute to recycling of nucleosides derived from extracellular nucleoside phosphates and metabolic salvage ...
  https://link.springer.com/article/10.1007%2Fs11302-006-9003-5
*  Plus it
... in a position to further analyze the details of G protein-coupled receptor/G protein coupling and the influence of additional ... Cooper DMF and Rodbell M (1979) ADP is a potent inhibitor of human platelet plasma membrane adenylate cyclase. Nature (Lond) ... Dangelmaier C, Jin J, Daniel JL, Smith JB, and Kunapuli SP (2000) The P2Y1 receptor mediates ADP-induced p38 kinase-activating ... 3H]Inositol phosphates were quantified by Dowex chromatography followed by liquid scintillation counting as described ...
  http://molpharm.aspetjournals.org/content/64/5/1210
*  Plus it
... or protein kinase G-mediated mechanism, or via prostaglandin release and activation of adenylate cyclase-coupled prostaglandin ... P2Y4 and P2Y6 receptor promoted a steady accumulation of inositol phosphates for up to 60 min (Figs. 2A and3A). Although the ... However, studies with the P2Y2(−/−) mouse indicate that additional or alternative receptors control ion transport responses to ... by protein kinase C is required for acute activation of cystic fibrosis transmembrane conductance regulator by protein kinase A ...
  http://jpet.aspetjournals.org/content/297/1/43
*  US20080008694A1 - Methods to prevent and treat diseases - Google Patents
An analogous effect is produced by choleratoxin, e.g., cAMP is a ubiquitous cofactor for many protein kinases, some of which ... In other words, the EF (adenylate cyclase) that produces cAMP would encounter a reduced pool of ATP in the presence of a given ... After the one hour of warm ischemia, hearts were removed, perfused for an additional four hours with buffer containing 1% ... delaying exhaustion of high-energy phosphates in the tissue, maintaining cell-membrane integrity in the tissue, inhibiting ...
  https://patents.google.com/patent/US20080008694A1/en
*  Plus it
... given the equilibrium nature of the Cr phosphokinase and adenylate kinase reactions (1, 7). What is unclear are the mechanisms ... 1973) A simplified method for the quantitative assay of small amounts of protein in biologic material. Anal Biochem 51:654-655. ... 1974) Glycolytic intermediates and high energy phosphates determined in biopsy samples of musculus femoris of man at rest. ... The major central responses to exercise in acute hypoxia compared with normoxia appear to involve additional increases in ...
  http://ajpregu.physiology.org/content/279/5/R1872
*  Frontiers | Genomic and proteomic evidences unravel the UV-resistome of the poly-extremophile Acinetobacter sp. Ver3 |...
... and proteins associated to amino acid and protein synthesis. Down-regulated proteins were related to several energy-generating ... and proteins associated to amino acid and protein synthesis. Down-regulated proteins were related to several energy-generating ... One was adenylate kinase, mentioned before, while the other was preliminary identified by MASCOT as a hypothetical protein. ... 6-biphosphate into triose phosphates: dehydroxyacetone phosphate and glyceraldehyde 3-phosphate; and (v) adenylate kinase ( ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2015.00328/full