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*  Cardiovascular response to hyperoxemia, hemodilution and burns : a clinical and experimental study
During preoperative acute normovolemic hemodilution a reduction of hemoglobin to 80 g/l did not compromise systolic or ... Conclusions: A reduction in hemoglobin to 80 g/l during acute normovolemic hemodilution does not normally compromise systolic ... Background: Preoperative acute normovolemic hemodilution may compromise oxygen transport. The aims of our study were to ... 1. Transesophageal echocardiographic hemodynamic monitoring during preoperative acute normovolemic hemodilution. Open this ...
  http://liu.diva-portal.org/smash/record.jsf?pid=diva2:17348
*  Hemodynamic Compensation during Acute Normovolemic Hemodilution | Anesthesiology | ASA Publications
Acute normovolemic hemodilution (ANH) causes a reduction in arterial oxygen content because of reduced hemoglobin concentration ... Hemodynamic Compensation during Acute Normovolemic Hemodilution You will receive an email whenever this article is corrected, ... Hemodynamic Compensation during Acute Normovolemic Hemodilution. Anesthesiology 4 2004, Vol.100, 1034. doi: ... Estafanous FG, Smith CE, Selim WM, Tarazi RC: Cardiovascular effects of acute normovolemic hemodilution in rats with ...
  http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1943322
*  ARTICLES | Journal of Applied Physiology
acute normovolemic hemodilution (ANH) reduces arterial hemoglobin (Hb) concentration, and thus arterial O2 content, triggering ... Although a slight reduction of mucosal oxygenation was observed at 40 ml/kg exchange, the mucosal μHbO2 still approximated ... Wu J, Mo L, Tan J, and Peng W. The effects of moderate acute normovolemic hemodilution on intestinal oxygen supply and ... Acute normovolemic hemodilution (ANH) compromizes intestinal microcirculatory oxygenation; however, the underlying mechanisms ...
  http://jap.physiology.org/content/98/3/1070.featured-podcasts
*  Acute Normovolemic Hemodilution: The Subgroup of Patients Likely To Benefit Remains Uncertain | Anesthesiology | ASA...
Matot et al. reported a significant reduction in exposure to allogeneic blood transfusion by acute normovolemic hemodilution ( ... 4 The tolerance of lower intraoperative hemoglobin concentrations, together with the limitation of intraoperative fluid ... Acute Normovolemic Hemodilution: The Subgroup of Patients Likely To Benefit Remains Uncertain. Anesthesiology 6 2003, Vol.98, ... Matot I, Scheinin O, Jurim O, Eid A: Effectiveness of acute normovolemic hemodilution to minimize allogeneic blood transfusion ...
  http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1943434
*  Iron: Uses, Side Effects, Interactions, Dosage, and Warning
Preoperative acute hypervolemic hemodilution with hydroxyethylstarch: an alternative to acute normovolemic hemodilution? Anesth ... Hemoglobin diseases: Taking iron might cause iron overload in people with these conditions. If you have a hemoglobin disease, ... with or without leucocyte reduction, on acute-phase response to surgery for total knee replacement. Acta Anaesthesiol.Scand ... Goodnough, L. T., Monk, T. G., Despotis, G. J., and Merkel, K. A randomized trial of acute normovolemic hemodilution compared ...
  https://www.webmd.com/vitamins/ai/ingredientmono-912/iron
*  Protocols and Video Articles Authored by Pedro Cabrales (Translated to Russian)
Acute moderate isovolemic hemodilution was induced by two isovolemic hemodilution steps: in the first step, 6% 70-kDa dextran ( ... Blood Pressure Reduction Due to Hemoglobin Glycosylation in Type 2 Diabetic Patients Vascular Health and Risk Management. 2008 ... Fifteen anesthetized rats were subjected to a two-exchange normovolemic hemodilution of 40% of the circulating blood volume ... Low Oxygen-affinity Hemoglobin Solution Increases Oxygenation of Partially Ischemic Tissue During Acute Anemia Journal of the ...
  https://www.jove.com/author/Pedro_Cabrales?language=Russian
*  Blood management - Wikipedia
Shander A, Rijhwani TS (December 2004). "Acute normovolemic hemodilution". Transfusion. 44 (12 Suppl): 26S-34S. doi:10.1111/j. ... Better outcomes are achieved with the reduction or avoidance of exposure to allogeneic blood. Numerous clinical studies have ... increasingly clinicians are giving parenteral iron to ensure that the haemoglobin is increased the maximal amount before the ... This procedure is known as "Intraoperative Blood Salvage." Another technique, acute normovolemic hemodilution" involves the ...
  https://en.wikipedia.org/wiki/Blood_management
*  Anemia and Patient Blood Management in Hip and Knee Surgery:A Systematic Review of the Literature | Anesthesiology | ASA...
Preoperative acute hypervolemic hemodilution with hydroxyethylstarch: An alternative to acute normovolemic hemodilution? Anesth ... Transfusion triggers were set at hemoglobin less than 7 g/dl or hemoglobin between 7 and 10 g/dl and symptoms. The allogeneic ... with or without leucocyte reduction, on acute-phase response to surgery for total knee replacement. Acta Anaesthesiol Scand ... Karakaya D, Ustun E, Tur A, Baris S, Sarihasan B, Sahinoglu H, Guldogus F: Acute normovolemic hemodilution and nitroglycerin- ...
  http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1933342
*  Protocols and Video Articles Authored by Stephan M. Jakob
Acute Normovolemic Hemodilution Improves Oxygenation in Ischemic Flap Tissue Anesthesiology. Jun, 2002 , Pubmed ID: 12170063 ... We explored the effects of acute cardiac preload reduction and dobutamine on hepatic arterial (Qha) and portal venous (Qpv) ... pCO(2) gradients may not parallel blood flow changes because of concomitant changes in metabolism, hemoglobin, temperature, and ... During normovolemic hemodilution, the oxygenation may further deteriorate because of the lack of erythrocytes or improve ...
  https://www.jove.com/author/Stephan++M._Jakob
*  Blood Flow and Oxygen Transport sub-cluster 59
Frequently, removed blood is replaced with intravenous fluids to maintain euvolemia (acute normovolemic hemodilution [ANH]). ... ANH may present problems when the circuit prime causes further hemodilution and unacceptably low hemoglobin. This investigation ... reduction of systemic venous pressure, and increased cardiac output to achieve hemodynamic stabilization. To meet these ... Neutrophil elastase has been reported to play an important role in acute lung injury, which is a major cause of postoperative ...
  http://www.biomedsearch.com/cluster/74/Blood-Flow-and-Oxygen-Transport/sub-59-p5.html
*  The efficacy of intravenous aminocaproic acid in primary total hip and knee arthroplasty: a meta-analysis | SpringerLink
Hemoglobin reduction. Hemoglobin reduction was reported in two included studies [6, 10]. No significant heterogeneity was found ... normovolemic hemodilution, electrocautery, hypotensive anesthesia, and hemostatic agents [5]. However, many patients still ... It is known that significant blood loss may lead to acute anemia following a THA, and blood transfusions are often required for ... postoperative hemoglobin level (MD = 0.90, 95% CI 0.78 to 1.02, P , 0.00001), hemoglobin reduction (MD = − 0.75, 95% CI − 0.93 ...
  https://link.springer.com/article/10.1186/s13018-018-0802-5
*  Prolonged Severe Anemia and Transfusion Refusal Following Abdominal Surgery. A Case Report and Short Literature Review | OMICS...
... acute normovolemic hemodilution [8,9], minimization of intra operative blood losses and optimization of tolerance of anemia [10 ... the severe reduction in hemoglobin. It is only possible to act on cardiac output by administering fluids, crystalloids and ... 2011) Evaluation of acute normovolemichemodilution and autotransfusion in neurosurgical patients undergoing excision of ... Minimal hemoglobin level that definitely compromises the process of wound healing is not clear. In animals, the effect of acute ...
  https://www.omicsonline.org/open-access/prolonged-severe-anemia-and-transfusion-refusal-following-abdominal-surgery-a-case-report-and-short-literature-review-2155-9864-1000328.php?aid=65294
*  Antepartum and Postpartum Hemorrhage - Prediction and Management - The Clinical Advisor
Normovolemic hemodilution is possible in cases when the potential for blood loss has been determined preoperatively. A few case ... Recent work describing obstetric management by leaving the placenta in situ shows a reduction in acute operative blood loss and ... The hemoglobin level should be optimized in the outpatient setting and a written plan for management of hemorrhage created, to ... Acute increases in pulmonary vascular resistance leading to acute pulmonary hypertension have also been reported. ...
  https://www.clinicaladvisor.com/anesthesiology/antepartum-and-postpartum-hemorrhage--prediction-and-management/article/580719/
*  New title
To test the hypothesis that Acute reduction of haemoglobin acute severe haemodilution concentration to 7 g/dl does not produce ... on hemodynamic variables 40 patients scheduled for radical Overall, acute normovolemic hemodilution during acute normovolemic ... hetastarch of acute normovolemic hemodilution.. All patients underwent moderate During hemodilution, anesthetized patients ... Recommend normovolemic severe haemodilution as a safe method of managing acute massive anticipated blood To evaluate the ...
  http://gotomydoctor.com/a/ansatt.hig.no1.html
*  Circuitul perfuziilor minime şi managementul fluidelor (volum) | Chirurgie cardiotoracică şi vasculară
Acute normovolemic hemodilution reduces allogeneic red blood cell transfusion in cardiac surgery: a systematic review and meta- ... Significant reduction in blood loss in patients undergoing minimal extracorporeal circulation. Gerritsen WB, van Boven WJ, ... Effects of a multimodality blood conservation schema toward improvement of intraoperative hemoglobin levels and off-pump ... The effect of retrograde autologous priming volume on haemodilution and transfusion requirements during cardiac surgery. ...
  https://www.jw.org/ro/biblioteca-medicala/medicina-chirurgie-fara-sange/cardioMinPerfusCircFluidVolMng/
*  Predictors of packed red cell transfusion after isolated primary coronary artery bypass grafting - The experience of a single...
... preoperative hemoglobin ≤ 13 gm/dL, preoperative hematocrit ≤ 40%, serum creatinine > 100 μmol/L, Euro SCORE (standard/logistic ... acute perioperative normovolemic hemodilution and intraoperative blood salvage [9, 24, 25]. The adoption of available blood ... McDonald and McMillan, in 2005 [41], utilized the product of BSA (m2) and preoperative hemoglobin (gm/L) as an index for ... However, despite current reductions in transfusion requirements for patients undergoing CABG, many patients continue to require ...
  https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/1749-8090-4-20
*  US7643858B2 - System and method for detection of brain edema using spectrophotometry - Google Patents
Schou, Henning, et al., "Uncompensated Blood Los is not Tolerated During Acute Normovolemic Hemodilution in Anesthetized Pigs, ... Apparatus for measuring hemoglobin US5735284A (en) 1992-06-24. 1998-04-07. N.I. Medical Ltd.. Method and system for non- ... after weight reduction," Journal of Applied Physiology, vol. 87, pp. 294-298 (1999). ... Apparatus for measuring hemoglobin US5860919A (en) 1995-06-07. 1999-01-19. Masimo Corporation. Active pulse blood constituent ...
  https://patents.google.com/patent/US7643858
*  Patent US5929031 - Storage stable hemoglobin solutions - Google Patents
Methods for preparing such storage stable hemoglobin solutions are also provided as well as a systems for storing the solutions ... The present invention relates to storage stable hemoglobin solutions which contain partially deoxygenated and surprisingly low ... acute normovolemic hemodilution or hemoaugmentation).. Because the hemoglobin of the instant invention can bind nitric oxide ... In addition to the reduction of functionality of a hemoglobin solution by the formation of methemoglobin, the protein portions ...
  http://www.google.com.au/patents/US5929031
*  Successful perioperative management of a patient with erythropoietin-producing uterine myoma | JA Clinical Reports | Full Text
Preoperative phlebotomy and isovolemic hemodilution were performed to prevent arterial and venous thrombosis, following ... previous evidence that a hemoglobin level < 16 g/dl reduces the occurrence of polycythemia vera-related complications. ... Preoperative levels of hemoglobin and erythropoietin were 21.9 g/dl (normal 11.5-15 g/dl) and 23.2 IU/ml (normal 4.2-23.7 IU/ml ... Moreover, acute normovolemic hemodilution is helpful in cases that involve the potential for massive bleeding, as it reduces ...
  https://jaclinicalreports.springeropen.com/articles/10.1186/s40981-018-0185-y
*  December 2017 - ORBCoN
Other techniques may include acute normovolemic hemodilution (ANH) and intraoperative autologous transfusion which may be ... Many sites are collecting the percent of transfusions that occur in patients with pre-transfusion hemoglobins less than 80g/L ... Quality improvement initiatives in Transfusion Medicine continue to increase and the reduction of unnecessary tests/procedures ... If acute postoperative bleeding is suspected, the surgeon should consider reoperation promptly. Postoperatively, judicious use ...
  http://transfusionontario.org/en/december-2017/
*  Mild Hypothermia Has Minimal Effects on the Tolerance to Severe Progressive Normovolemic Anemia in Swine | Anesthesiology | ASA...
Koehntop DE, Belani KG: Acute severe hemodilution to a hemoglobin of 1.3 g/dl tolerated in the presence of mild hypothermia. A ... In this connection, it may be noted that the observed decrease in DO2at the start of hypothermia matched the reduction in VO2( ... Chaney MA, Aasen MK: Severe acute normovolemic hemodilution and survival (letter; comment). Anesth Analg 1993; 76: 1371-2Chaney ... The main findings in this animal study were that mild hypothermia, induced before progressive acute normovolemic anemia, (1) ...
  http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1943813
*  Absence of Beneficial Effect of Acute Normovolemic Hemodilution Combined with Aprotinin on Allogeneic Blood Transfusion...
Perioperative patient hemoglobin and coagulation variables are shown in figure 2. Baseline hematocrit values (control, 43.2 ± ... Petry AF, Jost J, Sievers H: Reduction of homologous blood requirements by blood-pooling at the onset of cardiopulmonary bypass ... Laurent Höhn, Alexandre Schweizer, Marc Licker, Denis R. Morel; Absence of Beneficial Effect of Acute Normovolemic Hemodilution ... Bryson GL, Laupacis A, Wells GA, for the International Study of Perioperative Transfusion: Does acute normovolemic hemodilution ...
  http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1945062
*  Use of Tranexamic acid is a cost effective method in preventing blood loss during and after total knee replacement | Journal of...
... the mean drop in the post-op haemoglobin in Group-I was 1.49 gm/dl (unilateral) and 1.94 gm/dl (bilateral), with a mean ... The mean drop in the post-operative haemoglobin concentration in Group-II for unilateral and bilateral cases was 1.79 gm/dl and ... Bryson GL, Laupacis A, Wells GA: Does acute normovolemic hemodilution reduce perioperative allogeneic transfusion? A meta- ... Our results demonstrate significant reduction in blood loss with the use of tranexamic acid. Other studies have also had ...
  https://josr-online.biomedcentral.com/articles/10.1186/1749-799X-6-22
*  Metoprolol Reduces Cerebral Tissue Oxygen Tension after Acute Hemodilution in Rats | Anesthesiology | ASA Publications
... both heart rate and stroke volume increase in proportion to the reduction in hemoglobin concentration until very low hemoglobin ... Johannes T, Mik EG, Nohe B, Unertl KE, Ince C: Acute decrease in renal microvascular PO2 during acute normovolemic hemodilution ... 36 We hypothesize that acute β-blockade will limit the cardiovascular response to acute hemodilution, resulting in a reduction ... In this model of acute hemodilution (50% reduction in blood oxygen content ), cerebral tissue oxygen tension was relatively ...
  http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1932247
*  Medical Journal of Indonesia - ISSN: 0853-1773
Autologus normovolemic and hypervolemic hemodilution during surgery using 6% dextran 70 and lactated ringer solution: impact on ... Acute eye irritation study of a mixture of glyphosate isopropylamine salt and 2,4 D-isopropylamine Author(s): F. D. Suyatna , S ... The reduction of intraocular pressure after instillation of travoprost compared with timolol in chronic primary angle-closure ... hemoglobin and hematocrite (A preliminary study) Author(s): Ruswan Dachlan , Kristanto Kristanto , Eko Suprayogi. Volume: 15. ...
  http://journaldatabase.info/journal/issn0853-1773