*  Erythropoietin and Erythropoietin Receptor Expression in Human Cancer | Cancer Research
Autocrine stimulation by erythropoietin of autonomous growth of human erythroid leukemic cells in vitro. J. Clin. Investig., 88 ... Activating Mutations of the Noonan Syndrome-Associated SHP2/PTPN11 Gene in Human Solid Tumors and Adult Acute Myelogenous ... and induce differentiation of RBC precursors (1) . Expression of EPO and EPOR has recently been demonstrated in several ... HeLa cervical carcinoma cells, SHSY5Y neuroblastoma cells, U87 glioblastoma cells, U251 glioma cells, and U373 glioma cells. ...
  http://cancerres.aacrjournals.org/content/61/9/3561.long
*  Treosulfan Based Conditioning Acute Myeloid Leukaemia (AML)
A pediatric acute myeloid leukemia involving both myeloid and monocytoid precursors. At least 20% of non-erythroid cells are of ... Allogeneic haematopoietic cell transplantation for adult acute myeloid leukaemia in second remission: a retrospective study of ... Acute myeloid leukaemia presenting with bilateral breast masses.. A 46-year-old woman with a known history of acute myeloid ... Treosulfan and Fludarabine in Treating Younger Patients Who Are Undergoing a Donor Stem Cell Transplant for Acute Myeloid ...
  https://www.bioportfolio.com/resources/trial/68175/Treosulfan-Based-Conditioning-Acute-Myeloid-Leukaemia-AML.html
*  Risk of acute myeloid leukemia and myelodysplastic syndrome after autotransplants for lymphomas and plasma cell myeloma.
Exposures to DNA-damaging drugs and ionizing radiations increase risks of acute myeloid leukemia (AML) and myelodysplastic ... A pediatric acute myeloid leukemia involving both myeloid and monocytoid precursors. At least 20% of non-erythroid cells are of ... cell myeloma.". Exposures to DNA-damaging drugs and ionizing radiations increase risks of acute myeloid leukemia (AML) and ... Risk of acute myeloid leukemia and myelodysplastic syndrome after autotransplants for lymphomas and plasma cell myeloma.. 08:00 ...
  https://www.bioportfolio.com/resources/pmarticle/2111271/Risk-of-acute-myeloid-leukemia-and-myelodysplastic-syndrome-after-autotransplants-for-lymphomas.html
*  Study of Vidaza Versus Conventional Care Regimens for the Treatment of Acute Myeloid Leukemia (AML)
A pediatric acute myeloid leukemia involving both myeloid and monocytoid precursors. At least 20% of non-erythroid cells are of ... Leukemia, Biphenotypic, Acute. An acute leukemia exhibiting cell features characteristic of both the myeloid and lymphoid ... Relapse is the main cause of treatment failure after allogeneic stem cell transplant (alloSCT) in acute myeloid leukemia (AML) ... CC-486 Maintenance After Stem Cell Transplantation in Patients with Acute Myeloid Leukemia or Myelodysplastic Syndromes. ...
  https://www.bioportfolio.com/resources/trial/67616/Study-of-Vidaza-Versus-Conventional-Care-Regimens-for-the-Treatment-of-Acute.html
*  N-methyl-d-aspartate receptors in human erythroid precursor cells and in circulating red blood cells contribute to the...
Administration of NMDA/glycine to the cells at day 12 resulted in acute increase in the intracellular Ca2+ levels as shown in ... N-methyl-d-aspartate receptors in human erythroid precursor cells and in circulating red blood cells contribute to the ... N-methyl-d-aspartate receptors in human erythroid precursor cells and in circulating red blood cells contribute to the ... N-methyl-d-aspartate receptors in human erythroid precursor cells and in circulating red blood cells contribute to the ...
  http://ajpcell.physiology.org/content/305/11/C1123
*  Natural killer T cells contribute to the control of acute retroviral infection | Retrovirology | Full Text
NKT cells probably due to the fact that FV mainly infects erythroid precursor cells as well as granulocytes and B cells [17]. ... Thus, NKT cells activate and recruit several other cell types including NK cells, T cells, B cells, dendritic cells and ... NKT cells express markers, which are associated with the T cell (αβ T cell receptor) as well as the NK cell (e.g. NK cell ... FV inoculation into mice leads to infection of erythroid precursor cells as well as granulocytes and B cells [17]. FV consists ...
  https://retrovirology.biomedcentral.com/articles/10.1186/s12977-017-0327-8
*  Human parvovirus B19-induced aplastic crisis in an adult patient with hereditary spherocytosis: a case report and review of the...
HPV-B19 infects erythroid progenitor cells and inhibits erythropoiesis, leading to acute erythroblastopenia and ... The bone marrow in patients with transient aplastic crisis is characterized by an absence of maturing erythroid precursors and ... Saarinen UM,Chorba TL,Tattersall P,Young NS,Anderson LJ,Palmer E,Coccia PF,Human parvovirus B19-induced epidemic acute red cell ... The analysis of HPV-B19-induced epidemic acute red cell aplasia in 26 patients, primarily in children with hereditary hemolytic ...
  http://www.biomedsearch.com/nih/Human-parvovirus-B19-induced-aplastic/24618088.html
*  Abnormal Erythroid Precursor Cells | Lichtman's Atlas of Hematology 2016 | AccessHemOnc | McGraw-Hill Medical
... of acute alcoholism. The vacuoles usually occur in early erythroid cells as seen here and very occasionally in myeloid cells. ... Abnormal Erythroid Precursor Cells. In: MA L, MS S, RE F, N W. MA L, MS S, RE F, N W Eds. Lichtman MA, et al.eds. Lichtman's ... "Abnormal Erythroid Precursor Cells." Lichtman's Atlas of Hematology 2016 MA L, MS S, RE F, N W. MA L, MS S, RE F, N W Eds. ... Marrow cells of a patient with chronic and acute alcoholism. Note dyserythropoiesis. Small erythroblasts with scant cytoplasm. ...
  http://hemonc.mhmedical.com/content.aspx?bookid=1630§ionid=116917718
*  Acute erythroid leukemia - Wikipedia
Acute erythroid leukemias can be classified as follows: 50% or more of all nucleated bone marrow cells are erythroblasts, ... where the myeloproliferation is of erythroblastic precursors. It is defined as type "M6" under the FAB classification. The most ... Acute erythroid leukemia or Di Guglielmo syndrome is a rare form of acute myeloid leukemia (less than 5% of AML cases) ... Acute erythroid leukemia is rare, accounting for only 3-5% of all acute myeloid leukemia cases. One study estimated an ...
  https://en.wikipedia.org/wiki/Acute_erythroid_leukemia
*  Acute leukemia - Wikipedia
Forms of acute leukemia include: Acute myeloid leukemia Acute erythroid leukemia Acute lymphoblastic leukemia T-cell acute ... lymphoblastic leukemia Adult T-cell leukemia/lymphoma (Precursor)T-lymphoblastic leukemia/lymphoma Blast crisis of chronic ... Acute leukemia or acute leukaemia is a family of serious medical conditions relating to an original diagnosis of leukemia. In ... most cases, these can be classified according to the lineage, myeloid or lymphoid, of the malignant cells that grow ...
  https://en.wikipedia.org/wiki/Acute_leukemia
*  Acute myeloid leukemia diagnosis in the 21st century. - Free Online Library
Acute myeloid leukemia diagnosis in the 21st century. by 'Archives of Pathology & Laboratory Medicine'; Health, general Acute ... If there are more than 50% erythroid precursors, the erythroid progenitors are also excluded from the blast count. This is ... DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia. Cancer Cell. 2010; 17(1):13-27. ( ... Can cytoplasmic nucleophosmin be detected by immunocytochemical staining of cell smears in acute myeloid leukemia? ...
  https://www.thefreelibrary.com/Acute+myeloid+leukemia+diagnosis+in+the+21st+century-a0330499693
*  SWAP-70 regulates erythropoiesis by controlling α4 integrin | Haematologica
... is expressed in hematopoietic stem cells and myeloid-erythroid precursors. Although Swap-70-/- mice are not anemic, ... Allogeneic stem cell transplantation benefits for patients ≥ 60 years with acute myeloid leukemia and FLT3-ITD; a study from ... SWAP-70 deficiency impairs colony-forming unit erythroid (CFU-E) development, while burst-forming unit erythroid (BFU-E) ... Results We show that SWAP-70, a protein involved in cytoskeletal F-actin rearrangements and integrin regulation in mast cells, ...
  http://www.haematologica.org/content/early/2011/08/31/haematol.2011.050468
*  Adult Acute Myeloid Leukemia Treatment (PDQ®): Treatment - Health Professional Information [NCI]
Advances in the treatment of AML (also called acute myelogenous leukemia, acute nonlymphocytic leukemia, or ANLL) have resulted ... Estimated new cases and deaths from acute myeloid leukemia (AML) in the United States in 2010:[1] New cases: 12,330. Deaths: ... 50% or more erythroid precursors in the entire nucleated cell population of the bone marrow. ... Acute erythroid leukemias (FAB classifications M6a and M6b) The two subtypes of the acute erythroid leukemias, erythroleukemia ...
  http://healthmedicinet.com/content/nci/ncicdr0000062869.html
*  Aplastic anaemia associated with parvovirus B19 infection | Archives of Disease in Childhood
5 The above data suggest that all the three precursor cell lines in bone marrow might become the target cells of parvovirus B19 ... Experimental infections with parvovirus B19 in normal volunteers showed that not only erythroid production, but also myeloid ... In virus associated haemophagocytic syndrome with acute parvovirus B19 infection, raised cytokines such as interferon γ would ... Pure red cell aplasia may also develop with a persistent infection of parvovirus B19 in immunocompromised individuals.1 On the ...
  http://adc.bmj.com/content/87/5/436
*  E-cadherin Immunohistochemistry Stain and Acute Erythroid Leukemia, the Emerging Story | OMICS International
Ecadherin regulates cell-cell adhesions and controls mobility and proli.. ... E-Cadherin is calcium-dependent cell adhesion molecule encoded by CDH1 gene at chromosome 16q22.1. ... Acute erythroid leukemia is neoplastic proliferation of immature erythroid precursors in bone marrow with or without ... Of the five cases of acute erythroid leukemia, one case was pure erythroid leukemia (PEL) and the rest were acute erythroid ...
  https://www.omicsonline.org/open-access/ecadherin-immunohistochemistry-stain-and-acute-erythroid-leukemia-theemerging-story-2157-7099-1000352.php?aid=59564
*  Dr. David M Lucas - Cancer Researcher at OSUCCC - James
... role of transcriptional and translational regulation in tumor cell survival and drug resistance ... Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myeloid, Acute, Leukemia, Hairy Cell, Lymphoma, Leukemia, B-Cell, ... p53-/- synergizes with enhanced NrasG12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia. ... Acute Lymphoblastic Leukemia Treatment Acute Myeloid Leukemia Treatment Anal Cancer Treatment Basal Cell Carcinoma Treatment ...
  https://cancer.osu.edu/research-and-education/find-a-researcher/search-researcher-directory/david-m-lucas
*  CHEMOKINE GENE-MODIFIED CELLS FOR CANCER IMMUNOTHERAPY - Patent application
... lymphoid or erythroid lineages, or precursor cells thereof. For example, the diseases can arise from poorly differentiated ... Additional exemplary myeloid disorders include, but are not limited to, acute promyeloid leukemia (APML), acute myelogenous ... Following the incubation, cells are adjusted to 1×106 to 1×108 cells/mL, e.g., 1×107 cells/mL, e.g., 3×107 cells/mL, and ... 6. The population of cells of claim 1, wherein the bystander cells are from the cell line K562. 7. The population of cells of ...
  http://www.patentsencyclopedia.com/app/20110059137
*  Anemia of Chronic Disease (ACD) - ONA
... with a marked increase in storage iron and a reduced number of siderblasts combined with iron deficient erythroid precursors is ... Ferritin is an acute-phase reactant and may also increase with acute inflammation. ... The hemoglobin levels range from 7.0 to 11.0 g/dL, and the red blood cells (RBCs) vary little with a normal or slightly ... The erythrocytes are normocytic and normochromic and the white blood cells (WBCs) and platelets do not show morphologic ...
  https://www.oncologynurseadvisor.com/labmed/anemia-of-chronic-disease-acd/article/612038/
*  Pediatric Myelodysplastic Syndromes Pathology: Overview, Epidemiology, Clinical Features
... and frequent progression to a subset of acute myeloid leukemia (AML... ... a peculiar set of morphologic abnormalities in hematopoietic cells, increased marrow blasts in some cases, frequent ... A = multinucleate erythroid precursor; B = binucleate megaloblastoid erythroid precursor; C = dysplastic erythroid nuclei. View ... Common erythroid abnormalities in pediatric MDS are as follows:. * Blood: Bimodal red blood cell (RBC) distribution, ...
  https://emedicine.medscape.com/article/1976592-overview
*  DELIVERY OF AGENTS USING INTERFERING NANOPARTICLES - Patent application
... lymphoid or erythroid lineages, or precursor cells thereof. The diseases may arise from poorly differentiated acute leukemias, ... wherein the cell is a human cell, and wherein the cell is a liver cell. [0078] In another embodiment, the invention provides ... wherein the cell is a human cell, wherein the cell is a liver cell, and wherein the miRNA inhibitory agent is delivered at a ... carried out in eukaryotic cells, or eukaryotic non-human organisms, mammalian cells or organisms and human cells, e.g. cell ...
  http://www.patentsencyclopedia.com/app/20110263514
*  The Impact of FLT3 Mutations on the Development of Acute Myeloid Leukemias
... abnormalities with reduced B-cell precursors in the bone marrow and with a defect in the generation of dendritic cells in ... Gabbianelli and coworkers have previously reported that FLT3 mRNA expression is very rapidly lost during erythroid ... "All hematopoietic cells develop from hematopoietic stem cells through Flk2/Flt3-positive progenitor cells," Cell Stem Cell, vol ... AML cells; and overexpression of Lnk in these cells induces an inhibitory effect on ERK activation and cell proliferation [41]. ...
  https://www.hindawi.com/journals/lrt/2013/275760/
*  Protocols and Video Articles Authored by Uwe Christians
... and for STZ toxicity including acute tubular necrosis and accumulations of erythroid precursors. This adverse effect was ... Surprisingly, in C6 cells, SRL and RAD exposure resulted in high ROS concentrations without significant impairment of cell ... Mar, 2006 , Pubmed ID: 16491083 Cell-based diabetes therapy requires an abundant cell source. Here, we report reversal of ... In both, Bezielle inhibited cell proliferation, induced cell death and G2 cycle arrest by regulating the mediator proteins Jab1 ...
  https://www.jove.com/author/Uwe_Christians
*  CMDT Media Library | AccessMedicine | McGraw-Hill Medical
Note increased number of erythroid cells with basophilic cytoplasm. Many of these red blood cell precursors have a "tapioca ... Acute promyelocytic leukemia. (Bone marrow aspirate, 100 ×.) Note infiltration with immature myeloid cells characterized by a ... There is inversion of the usual myeloid-to-erythroid ratio (normally 2-4:1), with predominance of early erythroid cells ( ... There are numerous erythroid precursors with iron-laden mitochondria encircling the nucleus. These are referred to as ringed ...
  http://accessmedicine.mhmedical.com/MediaLibrary.aspx?termId=47174
*  CHEMICAL MODULATORS OF PRO-APOPTOTIC BAX AND BCL-2 POLYPEPTIDES - Patent application
... lymphoid or erythroid lineages, or precursor cells thereof. Preferably, the diseases arise from poorly differentiated acute ... Such assays can use cells of a cancer cell line or cells from a patient in the presence and absence of the compound of interest ... cell that is genetically deleted for BAX/BAK (i.e. negative control cell) is compared to that same cell in which BAX has been ... Ehrlich carcinoma cells, B16 melanoma cells, or Meth-A fibrosarcoma cells. Some of the injected mice are then treated ...
  http://www.patentsencyclopedia.com/app/20110218155
*  Application # 2017/0037033. OXOPIPERAZINE HELIX MIMETICS AS INHIBITORS OF THE p53-MDM2 INTERACTION - Patents.com
... or erythroid lineages, or precursor cells thereof Exemplary disorders include acute leukemias, e.g., erythroblastic leukemia ... erythroid cells, esophageal cells, gastric cells, gliomal cells, hematopoietic cells, kidney cells, lung cells, lymphoid cells ... erythroid cells, esophageal cells, gastric cells, gliomal cells, hematopoietic cells, kidney cells, lung cells, lymphoid cells ... erythroid cells, esophageal cells, gastric cells, gliomal cells, hematopoietic cells, kidney cells, lung cells, lymphoid cells ...
  http://patents.com/us-20170037033.html