*  A-836,339 - Wikipedia
A-836,339 is a drug developed by Abbott Laboratories that acts as a potent cannabinoid receptor full agonist. It is selective ... 2009). "Characterization of a cannabinoid CB2 receptor-selective agonist, A-836339 2,2,3,3-tetramethyl-cyclopropanecarboxylic ... 2009). "A CB(2) receptor agonist, A-836339, modulates wide dynamic range neuronal activity in neuropathic rats: contributions ... Uemura, N.; Fukaya, H. (2013). "Identification of a synthetic cannabinoid A-836339 as a novel compound found in a product". ...
  https://en.wikipedia.org/wiki/A-836,339
*  Menabitan - Wikipedia
... is a synthetic drug which acts as a potent cannabinoid receptor agonist. It is closely related to natural cannabinoids of the ... ISBN 978-0-412-46630-4. Reggio PH (1987). "Molecular determinants for cannabinoid activity: refinement of a molecular ... "Acute dose response of intraocular pressure to topical and oral cannabinoids". Proceedings of the Society for Experimental ...
  https://en.wikipedia.org/wiki/Menabitan
*  A-40174 - Wikipedia
A-40174 (SP-1) is an analgesic drug which acts as a potent cannabinoid receptor agonist, and was developed by Abbott ...
  https://en.wikipedia.org/wiki/A-40174
*  MAM-2201 - Wikipedia
... is a drug that presumably acts as a potent agonist for the cannabinoid receptors. It had never previously been reported in the ... Structurally, MAM-2201 is a hybrid of two known cannabinoid compounds JWH-122 and AM-2201, both of which had previously been ... 2012). "Analysis of synthetic cannabinoids in "spice-like" herbal highs: Snapshot of the German market in summer 2011". ... 2012). "Separation and structural characterization of the synthetic cannabinoids JWH-412 and 1-(5-fluoropentyl)-1H-indol-3yl]-( ...
  https://en.wikipedia.org/wiki/MAM-2201
*  EAM-2201 - Wikipedia
EAM-2201 (4'-ethyl-AM-2201, 5"-fluoro-JWH-210) is a drug that presumably acts as a potent agonist for the cannabinoid receptors ... EAM-2201 acts as a full agonist with a binding affinity of 0.380nM at CB1 and 0.371nM at CB2 cannabinoid receptors. EAM-2201 ... Structurally, EAM-2201 is a hybrid of two known cannabinoid compounds JWH-210 and AM-2201, both of which had previously been ... 1 July 2016). "Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice". Forensic Toxicology. ...
  https://en.wikipedia.org/wiki/EAM-2201
*  Org 28312 - Wikipedia
Org 28312 is a drug developed by Organon International which acts as a potent cannabinoid receptor full agonist at both the CB1 ... and structure-activity relationships of indole-3-carboxamides as novel water soluble cannabinoid CB1 receptor agonists". ... and CB2 receptors. It was developed with the aim of finding a water-soluble cannabinoid agonist suitable for intravenous use as ... relationship study of bicyclic piperazine analogs of indole-3-carboxamides as novel cannabinoid CB1 receptor agonists". ...
  https://en.wikipedia.org/wiki/Org_28312
*  STS-135 (drug) - Wikipedia
STS-135 acts a potent cannabinoid receptor agonist in vitro, with an EC50 of 51 nM for human CB2 receptors, and 13 nM for human ... CB1 receptors. STS-135 produces bradycardia and hypothermia in rats at doses of 1-10 mg/kg, suggesting cannabinoid-like ... "Effects of Bioisosteric Fluorine in Synthetic Cannabinoid Designer Drugs JWH-018, AM-2201, UR-144, XLR-11, PB-22, 5F-PB-22, ... "Bioisosteric Fluorine in the Clandestine Design of Synthetic Cannabinoids". Australian Journal of Chemistry. 68: 4. doi:10.1071 ...
  https://en.wikipedia.org/wiki/STS-135_(drug)
*  WIN 54,461 - Wikipedia
WIN 54,461 (6-Bromopravadoline) is a drug that acts as a potent and selective inverse agonist for the cannabinoid receptor CB2 ... "Cannabinoid Receptor Agonists and Antagonists". Current Pharmaceutical Design. 1 (3): 343-352. ...
  https://en.wikipedia.org/wiki/WIN_54,461
*  5F-CUMYL-PINACA - Wikipedia
5F-CUMYL-PINACA acts as a potent agonist for the cannabinoid receptors, with the original patent claiming approximately 4x ... is an indazole-3-carboxamide based synthetic cannabinoid. ...
  https://en.wikipedia.org/wiki/5F-CUMYL-PINACA
*  Org 28611 - Wikipedia
Org 28611 (SCH-900,111) is a drug developed by Organon International which acts as a potent cannabinoid receptor full agonist ... and structure-activity relationships of indole-3-carboxamides as novel water soluble cannabinoid CB1 receptor agonists". ... at both the CB1 and CB2 receptors. It was developed with the aim of finding a water-soluble cannabinoid agonist suitable for ... "Pharmacodynamic and pharmacokinetic effects of the intravenously administered CB1 receptor agonist Org 28611 in healthy male ...
  https://en.wikipedia.org/wiki/Org_28611
*  O-2113 - Wikipedia
O-2113 is a drug that is a classical cannabinoid derivative, which acts as a potent agonist for cannabinoid receptors, ... SULFONAMIDE CANNABINOID AGONISTS AND ANTAGONISTS. US Patent 7279500, Oct 9 2007. ...
  https://en.wikipedia.org/wiki/O-2113
*  PipISB - Wikipedia
PipISB is a drug used in scientific research which acts as a potent and selective inverse agonist of the cannabinoid receptor ... "Radiolabeling of a high potency cannabinoid subtype-1 receptor inverse agonist, N-(4-fluoro-benzyl)-4-(3-(piperidin-1-yl-indole ... PipISB in monkey as candidate radioligands for imaging brain cannabinoid type-1 receptors in vivo". Synapse. 63 (1): 22-30. doi ... It is highly selective for the CB1 receptor over CB2, with a Kd at CB1 of 1.5nM vs over 7000nM at CB2, has good blood-brain ...
  https://en.wikipedia.org/wiki/PipISB
*  ADB-FUBICA - Wikipedia
ADB-FUBICA is a drug that acts as a potent agonist for the cannabinoid receptors, with EC50 values of 2.6 nM at CB1 and 3.0 nM ... "Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F- ...
  https://en.wikipedia.org/wiki/ADB-FUBICA
*  APICA (synthetic cannabinoid drug) - Wikipedia
... is an indole based drug that acts as a potent agonist for the cannabinoid receptors. It had never previously been reported in ... The first published synthesis and pharmacological evaluation of APICA revealed that it acts as a full agonist at CB1 (EC50 = 34 ... and appears to be less potent than JWH-018 but more potent than THC. As of October 2015 APICA is a controlled substance in ... Pharmacological testing determined APICA to have an IC50 of 175 nM at CB1, only slightly less potent than JWH-018 which had an ...
  https://en.wikipedia.org/wiki/APICA_(synthetic_cannabinoid_drug)
*  AM-694 - Wikipedia
... is a drug that acts as a potent and selective agonist for the cannabinoid receptor CB1. It is used in scientific research for ... AM-694 is an agonist for cannabinoid receptors. Affinities are: with a Ki of 0.08 nM at CB1 and 18x selectivity over CB2 with a ... Regioselective F-18 radiolabeling of AM694, a CB1 cannabinoid receptor ligand. Journal of Labelled Compounds and ... AM-679 AM-1235 AM-2201 AM-2232 AM-2233 FUBIMINA JWH-018 List of AM cannabinoids List of JWH cannabinoids THJ-2201 WO patent ...
  https://en.wikipedia.org/wiki/AM-694
*  LBP-1 (drug) - Wikipedia
It acts as a potent and selective cannabinoid receptor agonist, with high potency at both the CB1 and CB2 receptors, but low ... Discovery of potent and orally bioavailable heterocycle-based cannabinoid CB1 receptor agonists. Bioorganic & Medicinal ... Design, synthesis and structure-activity relationships of (indo-3-yl) heterocyclic derivatives as agonists of the CB1 receptor ... and structure-activity relationships of indole-3-heterocycles as agonists of the CB1 receptor. Bioorganic & Medicinal Chemistry ...
  https://en.wikipedia.org/wiki/LBP-1_(drug)
*  A-834,735 - Wikipedia
A-834,735 is a drug developed by Abbott Laboratories that acts as a potent cannabinoid receptor full agonist at both the CB1 ... January 2008). "Differential effects of cannabinoid receptor agonists on regional brain activity using pharmacological MRI". ... identification and in vitro characterization of a series of potent cannabinoid ligands. In 2006 Symposium on the Cannabinoids. ... Poso, A.; Huffman, J. W. (2008). "Targeting the cannabinoid CB2 receptor: modelling and structural determinants of CB2 ...
  https://en.wikipedia.org/wiki/A-834,735
*  CUMYL-THPINACA - Wikipedia
CUMYL-THPINACA acts as a potent agonist for the cannabinoid receptors, with approximately 6x selectivity for CB1, having an ... CUMYL-THPINACA (also known as SGT-42) is an indazole-3-carboxamide based synthetic cannabinoid. ... EC50 of 0.1nM for human CB1 receptors and 0.59nM for human CB2 receptors. Sweden's public health agency suggested to classify ... 11 April 2013). "Patent WO 2014167530 - Cannabinoid compounds". New Zealand Patent application 623626. Retrieved 11 July 2015 ...
  https://en.wikipedia.org/wiki/CUMYL-THPINACA
*  5F-SDB-006 - Wikipedia
5F-SDB-006 is a drug that acts as a potent agonist for the cannabinoid receptors, with an EC50 of 50 nM for human CB1 receptors ... and 123 nM for human CB2 receptors. It was discovered during research into the related compound APICA which had been sold ... "Effects of Bioisosteric Fluorine in Synthetic Cannabinoid Designer Drugs JWH-018, AM-2201, UR-144, XLR-11, PB-22, 5F-PB-22, ...
  https://en.wikipedia.org/wiki/5F-SDB-006
*  AB-FUBINACA - Wikipedia
AB-FUBINACA is a drug that acts as a potent agonist for the cannabinoid receptors, with Ki values of 0.9 nM at CB1 and 23.2 nM ... doi:10.1007/s11419-012-0171-4. Jordan Trecki; Roy R. Gerona; Michael D. Schwartz (July 2015). "Synthetic Cannabinoid-Related ... Janez Klavž; Maksimiljan Gorenjak; Martin Marinšek (August 2016). "Suicide attempt with a mix of synthetic cannabinoids and ... "Schedules of Controlled Substances: Temporary Placement of Four Synthetic Cannabinoids Into Schedule I". Drug Enforcement ...
  https://en.wikipedia.org/wiki/AB-FUBINACA
*  SDB-006 - Wikipedia
SDB-006 is a drug that acts as a potent agonist for the cannabinoid receptors, with an EC50 of 19 nM for human CB2 receptors, ... and 134 nM for human CB1 receptors. It was discovered during research into the related compound SDB-001 which had been sold ... "Effects of Bioisosteric Fluorine in Synthetic Cannabinoid Designer Drugs JWH-018, AM-2201, UR-144, XLR-11, PB-22, 5F-PB-22, ... "In vitro metabolism of new synthetic cannabinoid SDB-006 in human hepatocytes by high-resolution mass spectrometry". Forensic ...
  https://en.wikipedia.org/wiki/SDB-006
*  CUMYL-PICA - Wikipedia
CUMYL-PICA acts as a potent agonist for the cannabinoid receptors, with approximately 20x selectivity for CB1, having an EC50 ... CUMYL-PICA (SGT-56) is an indole-3-carboxamide based synthetic cannabinoid. It is the α,α-dimethylbenzyl analogue of SDB-006. ... of 0.66nM for human CB1 receptors and 13nM for human CB2 receptors. 5F-CUMYL-PINACA 5F-SDB-006 CUMYL-PINACA CUMYL-THPINACA SDB- ... 11 April 2013). "Patent WO 2014167530 - Cannabinoid compounds". New Zealand Patent application 623626. Retrieved 11 July 2015. ...
  https://en.wikipedia.org/wiki/CUMYL-PICA
*  AM-2201 - Wikipedia
... is a recreational designer drug that acts as a potent but nonselective full agonist for the cannabinoid receptor. It is part of ... AM-2201 is a full agonist for cannabinoid receptors. Affinities are: with a Ki of 1.0 nM at CB1 and 2.6 nM at CB2. The 4-methyl ... "First European case of convulsions related to analytically confirmed use of the synthetic cannabinoid receptor agonist AM-2201 ... suggesting potent cannabinoid-like activity. AM-2201 metabolism differs only slightly from that of JWH-018. AM-2201 N- ...
  https://en.wikipedia.org/wiki/AM-2201
*  O-774 - Wikipedia
O-774 is a classical cannabinoid derivative which acts as a potent agonist for the cannabinoid receptors, with a Ki of 0.6 nM ... 1998 Oct 22;41(22):4400-7. PMID 9784115 The Cannabinoid Receptors. Part I. Cannabinoid Receptor Ligands and Structure-Activity ... and very potent cannabinoid effects in animal studies. AM-2232 O-1057 O-1812 Singer M, et al. Potent cyano and carboxamido side ...
  https://en.wikipedia.org/wiki/O-774
*  CUMYL-PINACA - Wikipedia
CUMYL-PINACA acts as a potent agonist for the cannabinoid receptors, with approximately 3x selectivity for CB1, having an EC50 ... of 0.15nM for human CB1 receptors and 0.41nM for human CB2 receptors. In its pure form, it is described as a sticky oil which ... Dobaja M, Grenc D, Kozelj G, Brvar M. Occupational transdermal poisoning with synthetic cannabinoid cumyl-PINACA. Clin Toxicol ... CUMYL-PINACA (also known as SGT-24) is an indazole-3-carboxamide based synthetic cannabinoid. ...
  https://en.wikipedia.org/wiki/CUMYL-PINACA