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*  Intracoronary Thrombus and Platelet Glycoprotein IIb/IIIa Receptor Blockade With Tirofiban in Unstable Angina or Non-Q-Wave...
5 6 Blood markers of platelet activity and fibrin generation are usually increased.7 8 Antithrombotic therapy is effective to ... The clinical, ECG, and angiographic characteristics of tirofiban plus heparin and heparin alone were compared by χ2 test for ... The effects of tissue plasminogen activator, streptokinase, or both on coronary-artery patency, ventricular function, and ... Platelet adhesion, activation, and aggregation play a critical role in initiating steps in the pathogenesis of platelet-rich ...
  http://circ.ahajournals.org/content/100/15/1609
*  Multiple electrode aggregometry - Wikipedia
... is a test of platelet function in whole blood. The test can be used to diagnose platelet disorders, monitor antiplatelet ... and is the best overall measure of platelet activity. Adenosine diphosphate (ADP) is a platelet agonist. When it is added to ... The ASA Reagent is used as a quality control in the platelet function testing with Multiplate, allowing the assessment of ... This reagent is used as a quality control in Multiplate platelet function testing. The GPIIb/IIIa antagonist blocks the binding ...
  https://en.wikipedia.org/wiki/Multiple_electrode_aggregometry
*  Effects of Physical (In)activity on Platelet Function
B. Harrison and M. Lordkipanidzé, "Clinical tests of platelet function," in Platelets, A. D. Michelson, Ed., 2012. View at ... "Platelet activity, sensitivity to agonist, and platelet-leukocyte conjugate formation after long-term exercise," Platelets, vol ... W. K. Drygas, "Changes in blood platelet function, coagulation, and fibrinolytic activity in response to moderate, exhaustive, ... Effects of Physical (In)activity on Platelet Function. Stefan Heber and Ivo Volf ...
  https://www.hindawi.com/journals/bmri/2015/165078/ref/
*  Flashcards - drugs
Monitor CBC, platelet count, serum renal/hepatic function tests, Hgb, daily bowel activity, ... Monitor hepatic function tests. Monitor daily pattern of bowel activity, stool consistency. Check for myalgia, arthralgia, ... Monitor hepatic function tests, CPK.*Pt. Teaching: • Follow special diet (important part of treatment). • Periodic lab tests ... Monitor hepatic function tests.*Patient Teaching: • Follow special diet (important part of treatment). • Periodic lab tests are ...
  https://www.freezingblue.com/flashcards/print_preview.cgi?cardsetID=172231
*  Patent US7534620 - Method and device for monitoring platelet function - Google Patents
The flow and composition change in response to the formation of a platelet mass in the passageway. Devices, articles, and kits ... and monitoring the flow or composition of the blood in the passageway to detect the platelet mass. ... the body of the mammal through a passageway to contact an obstruction or irregularity in the passageway to generate a platelet ... The invention provides a method of monitoring platelet function in a mammal by passing blood removed from ...
  http://www.google.com/patents/US7534620?dq=5,241,671
*  The Inhibition of Platelet Antiaggregating Activity of Clopidogrel by Atorvastatin Detected by Erythromycin Breath Test: a...
Blood samples will also be obtained to assess platelet function. The criteria for exclusion are patient refusal or inability to ... The Inhibition of Platelet Antiaggregating Activity of Clopidogrel by Atorvastatin Detected by Erythromycin Breath Test: a ... A new test called the erythromycin breath test will be administered to you three times during the study to measure how your ... Platelet Aggregation Inhibitors. Anticholesteremic Agents. Hypolipidemic Agents. Antimetabolites. Molecular Mechanisms of ...
  https://clinicaltrials.gov/ct2/show/NCT00004564?recr=Open&cond=%22Platelet+Aggregation+Inhibitors%22&rank=15
*  Thrombocyte Activity Reassessment and GEnoTyping for PCI(TARGET-PCI) - Full Text View - ClinicalTrials.gov
... algorithm for guided antiplatelet therapy integrating genotyping and platelet function testing.. *Utilizing Patient ... Physicians will be blinded to genotyping and platelet function results for subjects randomized to the standard therapy group ... Platelet Reactivity, Verify Now [ Time Frame: 6 months ]. To determine the stability of platelet reactivity over time as ... Platelet Mapping and Ischemic Event [ Time Frame: 6 months ]. To determine a relation between platelet mapping results and ...
  https://clinicaltrials.gov/ct2/show/NCT01177592
*  Platelet count decreased with Prozac
PLATELET COUNT DECREASED Causes, Patient Concerns and Latest Treatments and Prozac Reports and Side Effects. ... Grade 4/5 Motor Activity Log (MAL) Arm Use Scale; Grade 4/5 MAL Arm Use scale; Grade 4/5 Wolf Motor Function Test Performance ... test results; Correlation between cognitive functioning and cerebral metabolism by correlating neuropsychological testing ... PLATELET COUNT DECREASED Symptoms and Causes. Platelets, also known as thrombocytes, are small pieces of blood cells. They form ...
  http://patientsville.com/i.htm?q=PLATELET%20COUNT%20DECREASED&mp=Prozac
*  Characterization of a novel splicing mutation in UNC13D gene through amplicon sequencing: a case report on HLH | BMC Medical...
Blood analysis and liver function test showed significant decrease of platelets and NK-cell activity, along with high level of ... Liver function test resulted in alanine aminotransferase (ALT) of 379 IU/L, aspartate transaminase (AST) of 158 IU/L, and ... Platelets (PLT), white blood cell (WBC) and red blood cell (RBC) were measured to be 50 × 109/L, 3.5 × 109/L and 2.8 × 1012/L, ... Low NK-cell activity (4.75%) and low plasma albumin (19.2 g/L) were also observed. The bone marrow examination suggested ...
  https://bmcmedgenet.biomedcentral.com/articles/10.1186/s12881-017-0489-1
*  A Study of the Pharmacokinetics, Pharmacodynamics, and Safety of ARC1779 Injection in Patients With Von Willebrand Disease Type...
... platelet function analyzer (PFA-100®) closure time, bleeding time (BT), VWF multimer test, VWF: platelet-binding (VWF:PB) ... platelet count, concentration of VWF antigen (VWF:Ag), VWF ristocetin cofactor activity (VWF:RCo), Factor VIII (FVIII) activity ... activity, etc.). *Thrombocytopenia (defined as a platelet count , 100 per nL on at least 2 occasions within the month preceding ... To evaluate the effect of ARC1779 Injection on platelet counts in vWD-2B patients who have thrombocytopenia at baseline. [ Time ...
  https://clinicaltrials.gov/ct2/show/record/NCT00694785
*  The Significance of Elevated Clotting Factor VIII
... platelet function tests, platelet count, activated clotting time and fibrinogen test. ... Another test which can also indicate the activity of this clotting factor is the partial thromboplastin time (PTT). Other tests ... A blood test for the assay of clotting factor VIII is frequently done to measure its activity inside the body. Blood is taken ... These different clotting factors function by following a pattern known as the coagulation cascade. Each factor plays different ...
  https://www.brighthub.com/science/medical/articles/75279.aspx
*  Refractoriness legal definition of refractoriness
Platelet function testing: auditing local practice and broader implications. Sexual refractoriness and the locomotion effects ... whereas others warn of the dangers related to loss of platelet activity because of over-handling and refractoriness.. ... Single-donor platelets are indicated for patients where allo-immunisation and refractoriness have occurred.. Bleeding in ...
  http://legal-dictionary.thefreedictionary.com/refractoriness
*  Magazine Archives - Page 4 of 161 - Minority Nurse
... the ENT guys order more platelets and some liver function tests. Her blood pressure has been stable. I finish my computerized ... 2:40 am: As I've now become to feel quite possessive of patient #1's platelet activity, I feel like celebrating as her number ... Before leaving the room, I do a platelet check.. 4:30 am: Platelets are done. Will this shift ever end? Whatever could go wrong ... The platelets have yet to be delivered, and no one has even called from the blood bank to say, "Come and get them," or even ...
  http://minoritynurse.com/category/magazine/page/4/
*  4 u1.0-b978-1-4160-4224-2..50040-5..docpdf - English
... test is of little clinical use in function diagnosing abruption Whole blood clotting time Platelet function Clot formation: 4-8 ... most sensitive test degradation products Euglobulin clot lysis time Fibrinolytic activity None in 2 hr Difficult to interpret ... Platelet concentrate 35-60 Platelets; small amounts of fibrinogen; ↑ Platelet count approximately 8000/mm3 factors V, VIII RBCs ... Although studies addressing this frozen plasma and platelets). The coagulation tests most frequentlyissue have found no ...
  https://www.slideshare.net/AimmyKhumpuangdee/4-u10b9781416042242500405docpdf
*  Patent US20020028517 - Novel method of platelet function analysis using platelet count - Google Patents
... have been activated with a platelet agonist in the absence of EDTA and using that difference as a measure of platelet activity. ... of platelets before a sample of platelets has been activated and after the activatable platelets are activated with a platelet ... indication of the platelet activity of the sample. There is also disclosed a method for using the electronic impedance cell ... counting technique for determining platelet activation wherein EDTA is used as a preservative by counting the platelets in an ...
  http://www.google.com/patents/US20020028517?dq=60/310,746
*  Novel Uses for Platelet Function Testing in the Clinical Laboratory: Where Are We Now? | Clinical Chemistry
... this is a situation of low response or high residual platelet activity, which is not a result of resistance. ... Novel Uses for Platelet Function Testing in the Clinical Laboratory: Where Are We Now?. Brad S. Karon, Gilles Montalescot, Neil ... platelet function testing; LTA, light transmission aggregometry; ARCTIC, Double Randomization of a Monitoring Adjusted ... Platelet function testing (PFT),7 usually performed by techniques such as light transmission aggregometry (LTA), has ...
  http://clinchem.aaccjnls.org/content/60/3/441
*  Final Report Summary - BASEFOOD (Sustainable exploitation of bioactive components from the Black Sea Area traditional foods) |...
4.b. Platelet aggregation tests using the PFA-100 platelet function analyser. Activated platelets play a key role in the ... exhibited relevant effects on platelet aggregation assessed using closure time as a functional measure of platelet activity ( ... Platelet activation markers and platelet aggregates were determined in basal conditions and under the effect of platelet ... Optimal platelet function is therefore, an important tool in the prevention of CVD.. Six plant food extracts (dill, sideritis, ...
  https://cordis.europa.eu/result/rcn/143081_en.html
*  Drug-induced platelet dysfunction - Renal and Urology News
Platelet function testing with light transmission aggregometry (LTA), the platelet function analyzer (PFA-100), or a template ... We recommend testing von Willebrand factor (VWF) activity, VWF antigen and either a PFA-100 or bleeding time. The VWF activity ... Platelet function assays:. *. Assays of platelet function include light transmission aggregometry (LTA), the PFA-100 and the ... without waiting for a test to assess platelet function.. What conditions can underlie drug-induced platelet dysfunction:. The ...
  https://www.renalandurologynews.com/hematology/drug-induced-platelet-dysfunction/article/597759/
*  Session 11 Evaluation Form
1. Describe the differences between PT, PTT, ACT, D-dimer and platelet function testing. ... and Factor X activity assays. ... the current clinical utility of BNP and NT-proBNP testing for ... 2. Describe antiphospholipid syndrome and discuss the relevance of Protein S & C testing, Factor 5 Leiden, ...
  https://form.jotform.com/82098610984971
*  "Methods for the measurement of platelet function" by Alan D. Michelson
The focus is on tests that can be used to monitor antiplatelet activity in the setting of cardiovascular disease and ... platelet surface P-selectin, platelet surface-activated glycoprotein IIb/IIIa, and leukocyte-platelet aggregates; TEG Platelet ... The tests described are platelet aggregometry; impedance aggregometry; VerifyNow (Accumetrics, San Diego, CA); Plateletworks ( ... Platelet Function Analyzer-100 (Siemens Healthcare Diagnostics, Inc., Deerfield, IL); phosphorylation of vasodilator-stimulated ...
  https://escholarship.umassmed.edu/peds_hematology/121/
*  Von Willebrand Disease | National Heart, Lung, and Blood Institute (NHLBI)
Platelet function test. This test measures how well your platelets are working. ... This test checks the clotting activity of factor VIII. Some people who have VWD have low levels of factor VIII activity, while ... No single test can diagnose VWD. Your doctor may recommend one or more blood tests to diagnose the disorder. These tests may ... This test is done if one or more of the first three tests are abnormal. It shows the structure of your von Willebrand factor. ...
  https://www.nhlbi.nih.gov/health-topics/von-willebrand-disease
*  Bleeding Disorders - The Clinical Advisor
For platelet function abnormalities, platelet aggregation studies need to be performed. Further testing of platelet function ... and its function (Ristocetin cofactor or von Willebrand factor activity). ... These screening tests do not rule out platelet function defects or von Willebrand disease thus specific testing for these ... For platelet function disorders, DDAVP and antifibrinolytics are the mainstays of therapy as well. For severe bleeding, ...
  http://www.clinicaladvisor.com/pediatrics/bleeding-disorders/article/623178/
*  A Novel Role for CD36 in VLDL-Enhanced Platelet Activation | Diabetes
... from rats deficient in Cd36 overcomes a number of problems associated with using antibodies in platelet function tests. The ... Miller NE, Nordoy A: Effects of human plasma lipoproteins on platelet aggregation and platelet factor 3 activity in vitro. ... Platelet aggregation.. Platelet aggregation studies were performed on an APACT-4 aggregometer. When platelets aggregate, ... to overcome potential problems of using antibodies in platelet function studies outlined below, we demonstrated that platelets ...
  http://diabetes.diabetesjournals.org/content/52/5/1248
*  AKC Canine Health Foundation
Because standard diagnostics do not assess platelet function, we propose to evaluate platelet function in dogs with chronic ... and platelet count. Unfortunately, these routine tests do not necessarily correlate with excessive biopsy-induced bleeding, ... to the research team will use two methods to evaluate platelet function in canine patients with chronic liver disease ... Humans with liver disease have abnormal platelet function that contributes to abnormal coagulation. ...
  http://www.akcchf.org/research/research-portfolio/02363-A.html
*  Assessment of platelet function in patients with stroke using multiple electrode platelet aggregometry: a prospective...
... were excluded if they had taken any NSAIDs or other agents that could affect platelet activity in the 2 weeks prior to testing. ... Nonetheless some may argue that this does not equate to similar platelet inhibition as detected by platelet function tests. ... Conflicting results exist about the effect of smoking on platelet function testing [20, 24, 34]. However in our study, ANCOVA ... Platelet function tests: a review of progresses in clinical application. BioMed Res Int. 2014; Article ID 456569. doi:10.1155/ ...
  https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-016-0778-x