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*  Neothramycin - Wikipedia
Ehrlich Ascites carcinoma, Walker carcinosarcoma-256, and light activity against leukemia L-1210 in mice. These activities ... The antibiotic activity, since these first studies, has been determined to be due to its direct binding of DNA. More ... It showed moderate activity towards malaria with an IC50 value of about 1 µg/mL. Neothramycin also showed high cytotoxicity ... Its activities against cancer warranted phase I testing of the drug. More recently, in 1991, anthramycin derivatives, which are ...
  https://en.wikipedia.org/wiki/Neothramycin
*  Comparison of Tacrolimus and Myfortic Versus Tacrolimus and Sirolimus
Walker. A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino ... They possess rotamase activity, which is inhibited by the immunosuppressant drugs that bind to them. ... rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. (Stedman, 25th ed) ...
  https://www.bioportfolio.com/resources/trial/69525/Comparison-of-Tacrolimus-and-Myfortic-Versus-Tacrolimus-and-Sirolimus.html
*  US4943579A - Water soluble prodrugs of camptothecin - Google Patents
... on the carcinostatic activity of camptothecin were based on inhibitor activity toward an experimentally transplanted carcinoma ... or Walker 256 tumor in rats (Chem. Rev. 23 (1973), 385; Cancer Treat. Rep., 60 (1967), 1007] stimulated synthetical researches ... Indolyl-3-glyoxylic acid derivatives with antitumoral activity US4296105A (en) 1981-10-20. Derivatives of doxorubicine, their ... Table 1 represents the aqueous solubility and the anti-tumor activity of these compounds. The anti-tumor testing was carried ...
  https://patents.google.com/patent/US4943579?oq=7%2C190%2C101
*  Selection of nitrogen mustard resistance in a rat tumor cell line results in loss of guanine-O6-alkyl transferase activity. |...
Cell killing, DNA-interstrand crosslinks, and DNA-protein crosslinks were assayed in nitrogen mustard-resistant Walker 256 ... carcinoma (WR) cells and the parent cell line (WS) after treatment with 5-[3-(2-chloroethyl)-1-triazenyl]imidazo-4-carboxamide ... Selection of nitrogen mustard resistance in a rat tumor cell line results in loss of guanine-O6-alkyl transferase activity.. S ... Selection of nitrogen mustard resistance in a rat tumor cell line results in loss of guanine-O6-alkyl transferase activity.. S ...
  http://molpharm.aspetjournals.org/content/30/1/77
*  Plus it
Lewis lung carcinoma, Human sarcoma HS1, Hepatoma 129, Walker 256 (intramuscular) and Cloudman melanoma (S91). Data are ... reported only on compounds which have not demonstrated sufficient activity in these systems to warrant further investigation. ... Almost all of the compounds were tested in Sarcoma 180, Carcinoma 755, Leukemia 1210, and KB cells in culture; some tests were ...
  http://cancerres.aacrjournals.org/content/25/9_Part_2/1626
*  Iguratimod prevents ovariectomy‑induced bone loss and suppresses osteoclastogenesis via inhibition of peroxisome proliferator...
Iguratimod is known for its anti‑inflammatory activities and therapeutic effects in patients with rheumatoid arthritis. It has ... previously been demonstrated that iguratimod attenuates bone destruction and osteoclast formation in the Walker 256 rat mammary ... gland carcinoma cell‑induced bone cancer pain model. Therefore, it was hypothesized that iguratimod may additionally exhibit ... It was demonstrated that iguratimod may prevent ovariectomy‑induced bone loss by suppressing osteoclast activity in vivo. ...
  https://www.spandidos-publications.com/mmr/16/6/8200/abstract
*  Taxodone - Wikipedia
Taxodone and taxodione possess in vivo activity against Walker intramuscular carcinosarcoma 256 in rats (25 and 40 mg/kg, ... respectively) and in vitro activity against cells derived from human carcinoma of the nasopharynx (KB) (ED50 = 0.6 and 3 ug/ml ... The antifeedant activity of natural plant products towards the larvae of Spodoptera littoralis". Spanish Journal of ... Ayhan Ulubelen, Gülaçti Topçu, Hee-Byung Chai and John M. Pezzuto (1999). "Cytotoxic Activity of Diterpenoids Isolated from ...
  https://en.wikipedia.org/wiki/Taxodone
*  A Study of the Safety and Pharmacokinetics of AGS-8M4 Given in Combination With Chemotherapy in Women With Ovarian Cancer
Walker. A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino ... Avelumab is a human anti-PD-L1 checkpoint inhibitor with clinical activity in multiple solid tumors. Here, we describe the ... There are 3 types of breast carcinoma in situ: DUCTAL CARCINOMA IN SITU; LOBULAR CARCINOMA IN SITU; and PAGET DISEASE OF THE ... It is a common histological type of ovarian CARCINOMA and ENDOMETRIAL CARCINOMA. There is a high frequency of co-occurrence of ...
  https://www.bioportfolio.com/resources/trial/70697/A-Study-of-the-Safety-and-Pharmacokinetics-of-AGS-8M4-Given-in.html
*  Antiproliferative and Cytotoxic Activities | SpringerLink
Human pancreatic carcinoma cell lines. MDR P-gp CEM/ADR5000 cells. Multidrug-resistant P-gp over expressing CEM/ADR5000 ... floccosum have antineoplastic effects in Walker-256 tumor-bearing rats. Chem Biol Interact 228:46-56CrossRefGoogle Scholar ... Cho JY, Kim AR, Jung JH et al (2004) Cytotoxic and pro-apoptotic activities of cynaropicrin, a sesquiterpene lactone on the ... Anesini C.A., Alonso M.R., Martino R.F. (2018) Antiproliferative and Cytotoxic Activities. In: Sülsen V., Martino V. (eds) ...
  https://link.springer.com/chapter/10.1007%2F978-3-319-78274-4_13
*  osteosarcoma cells 的翻译结果--cnki翻译助手
... from human transitional cell carcinoma (TCC) , rat Walker 256 carcinoma and mouse 7,12 dimethyl benz (a) anthracene (DMBA) ... Conclusion The BMP-2 can induce kinase activity of ERK and expression of c-fos/c-jun mRNA in rat osteosarcoma cells are reduced ... 某些源自外胚层的骨外实体瘤,它们并未浸润至骨组织,但可引起血钙显著增高,提示这些肿瘤可能分泌体液因子作用于骨导致溶骨。我们从人膀胱癌、大鼠乳腺癌(Walker 256)及
  http://dict.cnki.net/h_50068634000.html
*  Miltefosine - Wikipedia
It was highly effective against methylnitrosourea-induced mammary carcinoma, but less so on transplantable mammary carcinomas ... Miltefosine exerts its activity by interacting with lipids, inhibiting cytochrome c oxidase and causing apoptosis-like cell ... and relatively inactive on Walker 256 carcinosarcoma and autochthonous acetoxymethylmethylnitrosamine-induced colonic tumors of ... Initial in vivo investigation on the antineoplastic activity showed positive result, but then only at high dosage and at high ...
  https://en.wikipedia.org/wiki/Miltefosine
*  Modification of the endoplasmic reticulum in some mammalian oocytes.
tivation of synthetic activity dependent on Epstein, M. A. 1961 Some unusual features of fine structure observed in HeLa cells ... mitotic cells of Walker 256 carcinoma. J. BioThey might, in this manner, express rephys. Biochem. Cytol., 11: 227-236. gional ...
  https://www.docme.ru/doc/2179258/modification-of-the-endoplasmic-reticulum-in-some-mammali..
*  Patent US5846565 - Controlled local delivery of chemotherapeutic agents for treating solid tumors - Google Patents
The 3 H-labeled paclitaxel had a final specific activity of 0.019 μCi/mg and was obtained by mixing 3 H-labeled paclitaxel at ... such as the L1210 and rat Walker 256 carcinosarcoma (Venditti, J. M., and B. J. Abbott, Lloydia 30:332-348 (1967); Moertel, C. ... Phase I and II clinical trials of camptothecin in human patients with melanoma and advanced gastrointestinal carcinoma, however ... All of the rats recovered from the implant surgery and were indistinguishable from controls in terms of motor activity, ...
  http://www.google.com/patents/US5846565?dq=4393663
*  1 - Forex how is margin calculated
Sarcoma-180 ascites Leukemia L1210 Primary Lewis lung carcinoma Ehrlich ascites Walker 256 carcino-sarcoma (advanced) Dunning ... 2002). Best Results of the Antitumor Activity of cis-Dichlorodiammineplatinum(II) in Animal Systems Tumor Host Best Results ... DMBA-induced mammary carcinoma ICI 42, 464-induced myeloid and lymphatic leukemias Swiss white mice Swiss white mice Swiss ... expression is associated with advanced local invasion forex how is margin calculated human squamous cell carcinomas of the ...
  http://forex2morrow.com/forex-how-is-margin-calculated.html
*  Publications
Walker, G., Silberman, J.D., Karpov, S.A., Preisfeld, A., Foster, P., Ol Frolov, A., Novozhilov, Y., and Sogin, M.L. (2003). " ... Li, H., Veldhuis, M.J.W., and Post, A.F. (1998). "Alkaline phosphatase activities among planktonic communities in the northern ... "Gene expression profile of peripheral blood lymphocytes from renal cell carcinoma patients treated with IL-2, interferon-alpha ... Walker, G., Simpson, A.G.B., Edgcomb, V.P., Sogin, M.L., and Patterson, D.J. (2001). "Ultrastructural identities of ...
  http://www.mbl.edu/jbpc/publicationsparentpage/
*  Galatturoglicani - Metodo di Bella - Sito Ufficiale
Antiproliferative activity in vitro and in vivo of the spicamycin analogue KRN5500 with altered glycoprotein expression in ... Inhibitory effects of D-glucosamine on the growth of Walker 256 carcinosarcoma and on protein, RNA, and DNA synthesis. Cancer ... Bhuvarahamurthy V, Govindasamy S. Extracellular matrix components and proteolytic enzymes in uterine cervical carcinoma. Mol ... Maeda M, Takasuka N, Suga T, Uehara N, Hoshi A. Antitumor activity of a new series of platinum complexes: trans(+/-)-1,2- ...
  http://www.metododibella.org/it/Galatturoglicani.html
*  carcinosarcoma: Topics by WorldWideScience.org
... mouse Ca755 carcinoma and Walker W-256 carcinosarcoma) is essentially special: in contrary to hormone-dependant tumors, this ... The antitumor activity of the γ-Fe 2 O 3 nanoparticles strongly correlated with Fe 2+ release from the nanoparticles but not ... There are five subtypes: pleomorphic carcinoma, spindle cell carcinoma, giant cell carcinoma, carcinosarcoma and pulmonary ... como o carcinoma pleomórfico (CP, o carcinoma de células fusiformes (CCF, carcinoma de células gigantes (CCG, os ...
  https://worldwidescience.org/topicpages/c/carcinosarcoma.html
*  Cancers | Free Full-Text | The Multifaceted Roles of STAT3 Signaling in the Progression of Prostate Cancer | HTML
Suppresses AR activity.. [179,180]. Tofacitinib. Primarily a JAK3 inhibitor, but has some activity against JAK1 and therefore ... Walker, S.R.; Chaudhury, M.; Nelson, E.A.; Frank, D.A. Microtubule-targeted chemotherapeutic agents inhibit signal transducer ... Ji, J.; Wang, X.W. Clinical implications of cancer stem cell biology in hepatocellular carcinoma. Semin. Oncol. 2012, 39, 461- ... Has various pharmacological activities including inhibition of JAK2.. Inhibits PI3K pathway and AR activity in PCa cell lines. ...
  http://mdpi.com/2072-6694/6/2/829/htm
*  Analgesic effects of lappaconitine in leukemia bone pain in a mouse model [PeerJ]
Medhurst SJ, Walker K, Bowes M, Kidd BL, Glatt M, Muller M, Hattenberger M, Vaxclair J, O'Rcilly T, Wotherspoon G. 2002. A rat ... open field for spontaneous activity recording and evaluation. Score 0: free movement, same limb activity of treated limb as the ... A rat model of bone cancer pain induced by intra-tibia inoculation of Walker 256 mammary gland carcinoma cells.. Biochemical ... The then, bone pain group mouse began to exhibit reduced spontaneous activity, and decreased ground touch for the affected limb ...
  https://peerj.com/articles/936/
*  Testosterone, sex hormone-binding globulin, calculated free testosterone, and oestradiol in male vegans and omnivores | British...
Hill P., Wynder E., Garbaczewski L., Garnes H., Walker A. R. P. & Helman P. (1980). Plasma hormones and lipids in men at ... Sanders T. A. B. & Key T. J. A. (1987). Blood pressure, plasma renin activity and aldosterone concentrations in vegans and ... Rose D. P. (1986). The biochemical epidemiology of prostatic carcinoma. Progress in Clinical and Biological Research 222, 43-68 ... Acta Endocrinologica 104, 253-256.. Henderson B. E., Ross R. K., Pike M. C. & Casagrande J. T. (1982). Endogenous hormones as a ...
  https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/testosterone-sex-hormonebinding-globulin-calculated-free-testosterone-and-oestradiol-in-male-vegans-and-omnivores/27DDFF5DF01A55EA4E1ECDBA443B7896
*  Table of Contents | Cancer Research
Mixed Function Oxidase Activities of Established Human Colon Carcinoma Cell Lines in the Activation of Cyclophosphamide ... Topical Chemotherapy of Intradermal Walker 256 Carcinosarcoma with Diaziquone and Doxorubicin in the Rat ... Mixed Function Oxidase Activities of Established Human Colon Carcinoma Cell Lines in the Activation of Cyclophosphamide ... Activity of a Novel 4-Quinolinecarboxylic Acid, NSC 368390 [6-Fluoro-2-(2′-fluoro-1,1′-biphenyl-4-yl)-3-methyl-4- ...
  http://cancerres.aacrjournals.org/content/45/11_Part_1
*  US Pivotal Studies of Irinotecan in Colorectal Carcinoma | Cancer Network | The Oncology Journal
... demonstrated some activity in patients with refractory advanced cancer. Three pivotal phase II studies of 1 ... Preclinical studies of the purified drug demonstrated activity in. mouse L1210 leukemia and rat Walker carcinosarcoma.[9,10] ... with potential activity, tegafur, did not demonstrate significant. activity in a confirmatory trial when compared to 5-FU.[15] ... carcinoma. J Clin Oncol 6:469-475, 1988.. 7. Leichman CG, Fleming TR, Muggia FM, et al: Phase II study of. fluorouracil and its ...
  http://www.cancernetwork.com/review-article/us-pivotal-studies-irinotecan-colorectal-carcinoma
*  mammary cancer 更多例句 第1页--cnki翻译助手
FdUrd at doses in the range 5-100?μg/animal was effective against meningeal carcinomatosis using Walker 256 carcinoma cells in ... Mouse mammary cancer (Shionogi carcinoma-115) has been extensively used to analyze the mechanism of androgen-dependent cancer ... 1-, 2-, 3- and 9-Aminophenanthrenes produce mammary cancer with approximately the same activity when fed to female Sprague- ... and the comparatively long survival of patients after a primary diagnosis of this type of carcinoma. ...
  http://dict.cnki.net/dict_more_exm.aspx?c=157&searchword=mammary+cancer
*  Photodynamic Therapy of Cancer II | (1995) | Publications | Spie
In vitro experiments were performed on human bladder carcinoma cells to evaluate the efficiency of photodynamic activity of ... Active immunotherapy of Walker-256 carcinosarcoma by tumor-infiltrating lymphocytes associated with photodynamic therapy Author ... Seven-day Erlich carcinomas with a diameter of 0.5 cm transplanted hypodermically to the mice have been used as an experimental ... The photodynamic activity of these pigments in living tissues is probably determined by the monomeric pigment molecules formed ...
  http://spie.org/Publications/Proceedings/Volume/2325
*  OTA Report:Herbal Treatments
NCI tested pokeroot for antitumor activity 43 times; in one of these tests, activity was reported in the Walker 256 system, but ... Significant antitumor activity of Iscador was found in some animal tests (Lewis lung carcinoma, colon adenocarcinoma 38, and ... It has been found to have antitumor activity in two types of tests (Walker 256 system (736,737) and in Sarcoma Yoshida ascites ... Cervical erosion (Papanicolaou III and IV) -dysplasia, carcinoma in situ, or invasive carcinoma of the cervix *Kraurosis vulvae ...
  https://www.quackwatch.org/01QuackeryRelatedTopics/OTA/ota04.html