Biomedicines | Free Full-Text | Decoding the Pluripotency Network: The Emergence of New Transcription Factors | HTML
... whose expression level determines itself to be a transcriptional repressor or activator . ... Other Zinc Finger Proteins. Besides the above zinc finger proteins, several other identified zinc finger proteins, including ... 7. Zinc Finger Proteins. 7.1. Zfp206 (Zscan10). Zfp206 (zinc finger protein 206) is highly expressed in both mouse and human ... In a recent study, direct protein-protein interactions of both Sall4-Oct4 and Sall4-Sox2 were demonstrated by pull-down assay ...http://www.mdpi.com/2227-9059/1/1/49/htm
Repression by SSN 6 - TUP 1 is directed by MIG 1 , a repressor / activator protein ( transcription / yeast / zinc - finger...
Some repressors block the function of specific activators, whereas others interfere with the transcriptional machinery (for ... MIG1 is a Cys2His2 zinc-finger protein related to the mammalian EGR1/Zif268 and WT1 (Wilms tumor) proteins (14). MIG1 binds to ... To test its function as a transcriptional repressor, we fused MIG1 to the LexA DNA-binding domain so that binding could be ... Here we present evidence that MIG1, a zinc-finger protein in the EGR1/Zif268 family, recruits SSN6-TUP1 to glucose-repressed ...https://www.semanticscholar.org/paper/Repression-by-SSN-6-TUP-1-is-directed-by-MIG-1-%2C-a-Treitel/2359ae45aceca48b54cbf409d803966164b96c47
A model for extradenticle function as a switch that changes HOX proteins from repressors to activators | The EMBO Journal
A model for extradenticle function as a switch that changes HOX proteins from repressors to activators. Julia Pinsonneault, ... EXD is the only factor that discriminates between HOX proteins as transcriptional activators in embryos, and HOX proteins as ... HOX proteins apparently act with the help of cofactors in larger nucleoprotein complexes (Mann, 1995). The protein-protein ... EXD as a co‐activator of DFD response elements. The EXD protein function has a critically important role in the maintenance of ...http://emboj.embopress.org/content/16/8/2032
Conversion of the LIN-1 ETS Protein of Caenorhabditis elegans from a SUMOylated Transcriptional Repressor to a Phosphorylated...
Phosphorylation of LIN-1 by ERK converts LIN-1 from a transcriptional repressor to a transcriptional activator. We examined how ... Proteins recruited by phosphorylated LIN-1 might reverse the chromatin modifications caused by transcriptional repressors, such ... Conversion of the LIN-1 ETS Protein of Caenorhabditis elegans from a SUMOylated Transcriptional Repressor to a Phosphorylated ... Conversion of the LIN-1 ETS Protein of Caenorhabditis elegans from a SUMOylated Transcriptional Repressor to a Phosphorylated ...http://www.genetics.org/content/199/3/761
GIS1 - Transcriptional activator/repressor GIS1 - Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) - GIS1...
Can act as a transcriptional activator (e.g. of stress genes like SSA3, HSP12 and HSP26) as well as a repressor (e.g. of ... pyrophosphate phosphatase DPP1). GIS1 also acts as a DNA damage-responsive transcriptional repressor of photolyase PHR1. ... Protein. Similar proteins. Organisms. Length. Cluster ID. Cluster name. Size. Q03833. C7GVP2. B5VFZ2. A0A250W9G7. G2WAK0. ... Transcriptional activator/repressor GIS1Add BLAST. 894. Amino acid modifications. Feature key. Position(s). DescriptionActions ...http://www.uniprot.org/uniprot/Q03833
The redox‐regulated SoxR protein acts from a single DNA site as a repressor and an allosteric activator | The EMBO Journal
The redox‐regulated SoxR protein acts from a single DNA site as a repressor and an allosteric activator. Elena Hidalgo, ... Autophagy proteins control goblet cell function by potentiating reactive oxygen species production Khushbu K Patel, Hiroyuki ...http://emboj.embopress.org/content/17/9/2629
Terf2ip - Telomeric repeat-binding factor 2-interacting protein 1 - Mus musculus (Mouse) - Terf2ip gene & protein
TRF2-interacting telomeric protein 1. Alternative name(s):. Repressor/activator protein 1 homolog. Short name: ... Protein-protein interaction databases. Protein interaction database and analysis system. More...IntActi. Q91VL8. 2 interactors. ... Protein-protein interaction databases. Protein interaction database and analysis system. More...IntActi. Q91VL8. 2 interactors. ... Protein. Similar proteins. Organisms. Length. Cluster ID. Cluster name. Size. Q91VL8. Q5EAN7. UPI000A318140. Mus musculus ( ...http://www.uniprot.org/uniprot/Q91VL8
Repressor activator protein 1-promoted colorectal cell migration is associated with the regulation of Vimentin. Tumour Biol ... Stat3 enhances vimentin gene expression by binding to the antisilencer element and interacting with the repressor protein, ZBP- ... Cullin2 (Cul2) is a core component of multiple ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, ... which mediate the ubiquitination of target proteins. Cul2 was predicted to be a tumor-suppressor protein that degrades ...http://cancerres.aacrjournals.org/content/78/15/4150
Emerging role of silent information regulator 1 (SIRT1) in hepatocellular carcinoma: a potential therapeutic target |...
TRF1-interacting protein 2. TPP1. POT1-TIN2 organizing protein. Rap1. Repressor/activator protein 1 ... Resveratrol is not a direct activator of SIRT1 enzyme activity. Chem Biol Drug Des. 2009;74:619-24.PubMedGoogle Scholar ... de Lange T. Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev. 2005;19:2100-10.PubMedGoogle ... Gang D, Hongwei H, Hedai L, Ming Z, Qian H, Zhijun L. The tumor suppressor protein menin inhibits NF-κB-mediated ...https://link.springer.com/article/10.1007/s13277-015-3488-x
The Dictyostelium bZIP transcription factor DimB regulates prestalk-specific gene expression | Development
Kawata, T., Early, A and Williams, J. G. (1996). Evidence that a combined activator-repressor protein regulates Dictyostelium ... activator; and DimB, functioning as a repressor. The relative occupancy of the -510 site by these two proteins would establish ... One obvious candidate for the activator is the previously mentioned MYB domain protein that binds to R2 but not R1 (M.F. and J. ... The ecmB oligonucleotide is the activator, that binds to DdSTATa and to an unidentified protein by virtue of repeated GAAA ...http://dev.biologists.org/content/133/3/439
TERF2IP Gene - GeneCards | TE2IP Protein | TE2IP Antibody
Protein Coding), TERF2 Interacting Protein, including: function, proteins, disorders, pathways, orthologs, and expression. ... Dopamine Receptor-Interacting Protein 5 3 4 * Repressor/Activator Protein 1 Homolog 3 4 ... Protein Symbol:. Q9NYB0-TE2IP_HUMAN. Recommended name:. Telomeric repeat-binding factor 2-interacting protein 1 Protein ... TERF2IP (TERF2 Interacting Protein) is a Protein Coding gene. Diseases associated with TERF2IP include Malignant Melanoma, ...http://www.genecards.org/cgi-bin/carddisp.pl?gene=TERF2IP
Similar articles for PubMed (Select 24918052) - PubMed - NCBI
Regulation of expression of the ethanol dehydrogenase gene (adhE) in Escherichia coli by catabolite repressor activator protein ... Molecular analysis of two ScrR repressors and of a ScrR-FruR hybrid repressor for sucrose and D-fructose specific regulons from ... In vitro binding of the pleiotropic transcriptional regulatory protein, FruR, to the fru, pps, ace, pts and icd operons of ... Regulation of the central glycolytic genes in Bacillus subtilis: binding of the repressor CggR to its single DNA target ...https://www.ncbi.nlm.nih.gov/pubmed?linkname=pubmed_pubmed&from_uid=24918052
Assessment 1 Flashcards by Christine Joyce | Brainscape
Activators & repressor proteins are aka gene regulatory proteins or transcription factors • Act like gene switches to turn ... CAP + cAMP = example of ligand activating an activator gene regulatory protein. • Repressor Proteins ◦ Decrease transcription ... Activator Proteins ◦ Increase the number of transcription starts. ◦ Inc. amount of gene transcribed ◦ ... Aka co-activator. • Molded like a puzzle piece b/w the activator and general transcription factor-polymerase complex ...https://www.brainscape.com/flashcards/assessment-1-6154596/packs/9488671
Control Of Gene Expression I Flashcards by Monica Kelley | Brainscape
The repressor binds to the activation domain of the activator protein. 50 ... Gene repressor proteins attract histone deacetylase to the promoter. What effect does this have on histones? ... Gene repressor proteins attract histone methyl transferases, which methylate histones. What is the function of the methylated ... After a gene repressor protein binds to DNA, what does it block? ... Where do gene regulatory proteins (activators or repressors) ...https://www.brainscape.com/flashcards/control-of-gene-expression-i-4784823/packs/6951705
Repression and Activation Domains of Rme1p Structurally Overlap, but Differ in Genetic Requirements
Some proteins act as activators in one context and as repressors in another. The precise mechanism of action of these proteins ... acts as both a transcriptional repressor and activator. Rme1p is a zinc-finger protein with no other homology to any protein of ... which may facilitate protein-protein interactions. These patches of similarity to other repressors and activators are ... Interaction of yeast repressor-activator protein Ume6p with glycogen synthase kinase 3 homolog Rim11p. Mol Cell Biol. 1997;17: ...http://pubmedcentralcanada.ca/pmcc/articles/PMC111138/?lang=en-ca
Regulation of two pair-rule strip... preview & related info | Mendeley
Activator and repressor proteins bind in vitro to several sites within the enhancer. These findings suggest a general model for ... The zinc finger repressor hunchback appears to be responsible for establishing the anterior border of stripe 3 and the ... The stripe 3 + 7 enhancer appears to be regulated by one or more ubiquitously distributed activators, including components of a ... The two-stripe pattern results via multiple tiers of repressors which delimit this ubiquitous activation. ...https://www.mendeley.com/research-papers/regulation-two-pairrule-stripes-single-enhancer-drosophila-embryo/
Rice proteins that bind single-stranded G-rich telomere DNA, Plant Molecular Biology | 10.1023/A:1005994719175 | DeepDyve
"Rice proteins that bind single-stranded G-rich telomere DNA, Plant Molecular Biology" on DeepDyve, the largest online rental ... Separation of transcriptional activation and silencing functions of RAP1encoded repressor/activator protein. 1. Isolation of ... Rice proteins that bind single-stranded G-rich telomere DNA. Rice proteins that bind single-stranded G-rich telomere DNA Kim, ... These proteins are called rice G-rich telomere binding protein (RGBP) and none of them show binding affinity to double-stranded ...https://www.deepdyve.com/lp/springer_journal/rice-proteins-that-bind-single-stranded-g-rich-telomere-dna-XzJHLkrG3a
SMART: PLP domain annotation
CRYSTAL STRUCTURE OF AHRC, THE ARGININE REPRESSOR/ACTIVATOR PROTEIN FROM BACILLUS SUBTILIS. ... Click on the protein counts, or double click on taxonomic names to display all proteins containing PLP domain in the selected ... Protein. Disease. Myelin proteolipid protein (P60201) (SMART). OMIM:312080: Pelizaeus-Merzbacher disease ; Spastic paraplegia-2 ... Myelin proteolipid protein (PLP or lipophilin) [(PUBMED:1711121)] is the major myelin protein from the central nervous system ( ...http://smart.embl-heidelberg.de/smart/do_annotation.pl?DOMAIN=PLP&BLAST=DUMMY
Vanderbilt University Medical Center
"Mechanisms of Transcription Activation by the DNA-Binding Transfactor Repressor Activator Protein 1 (Rapl) Uncovered Using an ... "Nuthin' but a G (protein) thang: Insights on G Protein Signaling Mechanics from Sequence and Structure" ...http://www.mc.vanderbilt.edu/calendar/?xtags=vumc&calendarview=week&month=05&day=2&year=2017
HKU Scholars Hub: Researcher Page
Prostaglandin E receptor subtype 4 and Repressor activator protein 1: Independent Multifaceted Metabolic Players. ... A study of tissue plasminogen activator in blood vessels: expression, regulation and vasorelaxing effect. Chinese Medicine/ ...http://hub.hku.hk/cris/rp/rp00234/achievements
RAP1 at the Yeast Telomere
cytogenetik, DNA-binding, Saccharomyces, yeast, telomeric repeat, telomere, RAP1, repressor activator protein 1, Genetics, ... contain a sequence resembling the consensus binding sequence of the major telomere-binding protein Repressor Activator Protein ... contain a sequence resembling the consensus binding sequence of the major telomere-binding protein Repressor Activator Protein ... contain a sequence resembling the consensus binding sequence of the major telomere-binding protein Repressor Activator Protein ...https://lup.lub.lu.se/search/publication/464700
Telomeric armor: the layers of end protection | Journal of Cell Science
The sixth protein, repressor activator protein 1 (RAP1), interacts exclusively with TRF2 (Li et al., 2000). Although all six ... Accessory proteins. TRF1 and TRF2, the focal point of protein-protein interactions at telomeres, share a common TRF homology ( ... It was first identified as a TRF2-interacting protein that exhibited significant sequence identity with the Rap1p protein from ... heterodimerization of the two proteins has not been observed. Curiously, the two proteins exploit the TRFH motif to recruit ...http://jcs.biologists.org/content/122/22/4013
Magni:Research - OpenWetWare
Synthetic circuits are composed by transcriptional and post-transcriptional regulators: activator/repressor proteins, small ... a synthetic bacterial self-destruction device for recombinant protein release; 3) mathematical studies that support the design ...https://openwetware.org/wiki/Magni:Research
HKU Scholars Hub: Phosphorylation influences the binding of the yeast RAP1 protein to the upstream activating sequence of the...
Yeast repressor activator protein 1 (RAP1) binds in vitro to specific DNA sequences that are found in diverse genetic elements ... Yeast repressor activator protein 1 (RAP1) binds in vitro to specific DNA sequences that are found in diverse genetic elements ... end of the activator core sequence. When the sequence flanking the 5' end of the activator core sequence was different from the ... end of the activator core sequence. When the sequence flanking the 5' end of the activator core sequence was different from the ...http://hub.hku.hk/handle/10722/178503
ASMscience | Reconstruction and Use of Microbial Metabolic Networks: the Core |span class='jp-italic'|Escherichia coli|/span|...
... proteins, and reactions. Network reconstructions have been used extensively to study the phenotypic behavior of wild-type and ... Regulation of expression of the ethanol dehydrogenase gene (adhE) in Escherichia coli by catabolite repressor activator protein ... above the protein. For complexes of multiple functional proteins, the proteins are connected with an "&" above the reaction. ... above the protein. For complexes of multiple functional proteins, the proteins are connected with an "&" above the reaction. ...http://www.asmscience.org/content/journal/ecosalplus/10.1128/ecosalplus.10.2.1