*  Abstract 307: Systemic Deficiency Of The Map Kinase Activated Protein Kinase 2 Reduces Atherosclerosis In Hypercholesterolemic...
Abstract 307: Systemic Deficiency Of The Map Kinase Activated Protein Kinase 2 Reduces Atherosclerosis In Hypercholesterolemic ... Abstract 307: Systemic Deficiency Of The Map Kinase Activated Protein Kinase 2 Reduces Atherosclerosis In Hypercholesterolemic ... Abstract 307: Systemic Deficiency Of The Map Kinase Activated Protein Kinase 2 Reduces Atherosclerosis In Hypercholesterolemic ... Abstract 307: Systemic Deficiency Of The Map Kinase Activated Protein Kinase 2 Reduces Atherosclerosis In Hypercholesterolemic ...
  http://circ.ahajournals.org/content/116/Suppl_16/II_43.2
*  Mitogen Activated Protein Kinase 1 (MAP Kinase 1 or MAPK 1 or Extracellular Signal Regulated Kinase 2 or ERK-2 or Protein...
Global Markets Direct's, 'Mitogen Activated Protein Kinase 1 (MAP... ... MAP Kinase 1 or MAPK 1 or Extracellular Signal Regulated Kinase 2 or ERK-2 or Protein Tyrosine Kinase ERK2 or EC 2.7.11.24) - ... 46 Pages Report] Check for Discount on Mitogen Activated Protein Kinase 1 ( ... Mitogen Activated Protein Kinase 1 (MAP Kinase 1 or MAPK 1 or Extracellular Signal Regulated Kinase 2 or ERK-2 or Protein ...
  http://www.reportsnreports.com/reports/648583-mitogen-activated-protein-kinase-1-map-kinase-1-or-mapk-1-or-extracellular-signal-regulated-kinase-2-or-erk-2-or-protein-tyrosine-kinase-erk2-or-ec-271124-pipeline-review-h1-2016.html
*  MAPKAPK2 Gene - GeneCards | MAPK2 Protein | MAPK2 Antibody
Mitogen-Activated Protein Kinase-Activated Protein Kinase 2, including: function, proteins, disorders, pathways, orthologs, and ... The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2. (PMID: 8280084) ... 1156 : Mitogen-activated protein kinase-activated protein kinases. IUPHAR :. *mitogen-activated protein kinase-activated ... This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=MAPKAPK2
*  OriGene - Mapkapk2 (NM 008551) Human ORF cDNA Clone
Mouse MAP kinase-activated protein kinase 2 (Mapkapk2) available for purchase from OriGene - Your Gene Company. ... GFP-tagged ORF clone of Mus musculus MAP kinase-activated protein kinase 2 (cDNA clone MGC:67217 IMAGE:5687007) in a GFP ... MAPKAPK2 (untagged)-Kinase deficient mutant (K93M) of Human mitogen-activated protein kinase-activated protein kinase 2 ( ... MAPKAPK2 (untagged)-Kinase deficient mutant (K93M) of Human mitogen-activated protein kinase-activated protein kinase 2 ( ...
  http://www.origene.com/Mouse_ORF/MR206027.aspx
*  Stretch-Induced MAP Kinase Activation in Cardiac Myocytes: Differential Regulation through β1-Integrin and Focal Adhesion Kinase
3.1 Mechanical stretch activates MAP kinase phosphorylation independent of AT1 and AT2. Mechanical stretch has been shown to ... including protein kinase C [5], p70/85 S6 kinase [6], as well as the MAP kinase family members ERK1/2 [4], p38 [7] and JNK [8] ... Mitogen-activated protein (MAP) kinases have been implicated in hemodynamic load induced heart failure. Both angiotensin II ( ... Pulsatile stretch activates mitogen-activated protein kinase (MAPK) family members and focal adhesion kinase (p125(FAK)) in ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2039913/?lang=en-ca
*  20-Hydroxyeicosatetraenoic Acid Mediates Angiotensin Ii-Induced Phospholipase D Activation in Vascular Smooth Muscle Cells |...
Ang II also stimulates the Ras/MAP kinase pathway, and MAP kinase activates cPLA2 and PLD in VSMC. The increase in Ras/MAP ... Inhibitors of ras farnesyltransferase (FPT III, 25 μM, 18 hr) and MAP kinase kinase (UO126, 10 μM) significantly attenuated the ... stimulates Ras/MAP kinase pathway, which in turn activates PLD and release additional AA. ... stimulation in VSMC from rabbit aorta is mediated by the Ras/MAP kinase pathway via AA metabolites generated by cPLA2. Ang II ( ...
  http://hyper.ahajournals.org/content/36/Suppl_1/723.1
*  KEGG SSDB Paralog Search Result: mmu:234135
mmu:17164 MAP kinase-activated protein kinase 2 K04443 386 129 ( -) 35 0.356 59 -, mmu:93695 glycoprotein (transmembrane) nmb ... mmu:225028 mitogen-activated protein kinase kinase kina K04406 894 105 ( -) 30 0.396 48 -, mmu:230824 grainyhead-like 3 ( ... mmu:53859 mitogen-activated protein kinase kinase kinas K04466 942 100 ( -) 29 0.308 52 -, mmu:66060 cysteine-rich ... mmu:107503 activating transcription factor 5 K09044 283 125 ( -) 34 0.636 22 -, mmu:11501 a disintegrin and metallopeptidase ...
  http://www.kegg.jp/ssdb-bin/ssdb_paralog?org_gene=mmu:234135
*  MAPKAPK2 - Wikipedia
MAP) kinase and MAP-kinase-activated kinases 1 and 2". Eur. J. Biochem. 217 (2): 715-22. doi:10.1111/j.1432-1033.1993.tb18297.x ... This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is ... MAP kinase-activated protein kinase 2 is an enzyme that in humans is encoded by the MAPKAPK2 gene. This gene encodes a member ... "Entrez Gene: MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2". Rane MJ, Coxon PY, Powell DW, Webster R, ...
  https://en.wikipedia.org/wiki/MAPKAPK2
*  KEGG PATHWAY: Thyroid hormone signaling pathway - Homo sapiens (human)
One binding site binds only T3 and activates the phosphatidylinositol 3-kinase (PI3K) pathway. The other binding site binds ... Pathway menu , Organism menu , Pathway entry , Download KGML , Show description , User data mapping ] The thyroid hormones (THs ... both T3 and T4 and activates the ERK1/2 MAP kinase pathway. ...
  http://www.kegg.jp/kegg-bin/show_pathway?hsa04919+117247
*  MAPKAPK2 | Cancer Genetics Web
MAP kinase-activated protein kinase 2 (MAPKAPK2), Cytochrome P450, family 24, subfamily A, polypeptide 1 (CYP24A1) and ... This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is ... The stress-activated p38 mitogen-activated protein kinase (MAPK)/MAPKAP kinase-2 (MK2) pathway is a critical component of the ... UNLABELLED: Mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2) is recognized as oncogenic and simulative ...
  http://www.cancerindex.org/geneweb/MAPKAPK2.htm
*  Vascular Cell
Normal endothelial but impaired arterial development in MAP-Kinase activated protein kinase 2 (MK2) deficient mice Letter to ... Erratum to: 'Normal endothelial but impaired arterial development in MAP-Kinase activated protein kinase 2 (MK2) deficient mice ...
  http://vascularcell.com/index.php/vc
*  TENM1 - Teneurin-1 - Homo sapiens (Human) - TENM1 gene & protein
Activates the mitogen-activated protein (MAP) kinase 2 (MEK2) and extracellular signal-regulated kinase (ERK) cascade. Acts ... positive regulation of MAP kinase activity Source: UniProtKB. *positive regulation of peptidyl-serine phosphorylation Source: ... Q9UKZ4-2]. NP_001156751.1. NM_001163279.1. NP_055068.2. NM_014253.3. [Q9UKZ4-1]. XP_011529532.1. XM_011531230.2. [Q9UKZ4-2]. XP ... Q9UKZ4-2]. NP_001156751.1. NM_001163279.1. NP_055068.2. NM_014253.3. [Q9UKZ4-1]. XP_011529532.1. XM_011531230.2. [Q9UKZ4-2]. XP ...
  http://www.uniprot.org/uniprot/Q9UKZ4
*  VEGF Signaling | www.antikoerper-online.de
Der p38 Signalweg übermittelt über MAPKAPK2/3 (MAP Kinase Activated Protein Kinase-2/3) und HSP27 (Heat Shock Protein-27) ... MAPK - Mitogen-Activated Protein Kinase: MAPK Antikörper MAPK ELISA Kits PRKCG - PKC gamma: PRKCG Antikörper PRKCG ELISA Kits ... SPHK1 - Sphingosine Kinase 1: SPHK1 Antikörper SPHK1 ELISA Kits SPHK1 Proteine SPHK2 - Sphingosine Kinase 2: SPHK2 Antikörper ... Ganju RK (1998): "Human immunodeficiency virus tat modulates the Flk-1/KDR receptor, mitogen-activated protein kinases, and ...
  http://www.antikoerper-online.de/vegf-signaling-pathway-124/
*  Tyrosine hydroxylase - Wikipedia
MAP) kinase and MAP-kinase-activated kinases 1 and 2". European Journal of Biochemistry / FEBS. 217 (2): 715-22. doi:10.1111/j. ... mitogen-activated-protein kinase-activating protein kinase) has a preference for Ser40, but also phosphorylates Ser19 about ... that are phosphorylated by a variety of protein kinases.[12][25] Ser40 is phosphorylated by the cAMP-dependent protein kinase.[ ... Tyrosine hydroxylase is activated by phosphorylation dependent binding to 14-3-3 proteins.[34] Since the 14-3-3 proteins also ...
  https://en.wikipedia.org/wiki/Tyrosine_3-monooxygenase
*  Staff Profile - Institute for Cell and Molecular Biosciences - Newcastle University
Specifically we are investigating the role of stress-activated MAP kinase pathways in mediating stress-induced changes in gene ... Peroxide sensors for the fission yeast stress-activated mitogen-activated protein kinase pathway. Molecular Biology of the Cell ... Enjalbert B, Smith DA, Cornell MJ, Alam I, Nicholls S, Brown AJP, Quinn J. Role of the Hog1 stress-activated protein kinase in ... Smith DA, Nicholls S, Morgan BA, Brown AJP, Quinn J. A conserved stress-activated protein kinase regulates a core stress ...
  http://www.ncl.ac.uk/camb/staff/profile/janetquinn.html
*  R827352C002 (Final)
... activates pro-inflammatory signaling pathways, e.g., the MAP kinase cascades. These cascades are involved in AP-1 ... An example of a Tier 1 antioxidant defense is the expression of HO-1. This gene is activated by the nuclear accumulation of ... Aim 2 was to use a murine model for asthma to study the effects of DEP on the enhancement of ovalbumin (OVA)-induced allergic ... Journal of Allergy and Clinical Immunology 2006;118(2):455-465. R827352 (Final). R827352C002 (Final). R832413 (2008). ...
  https://cfpub.epa.gov/ncer_abstracts/index.cfm/fuseaction/display.abstractDetail/abstract/8458/report/F
*  Gut microbiota translocation to the pancreatic lymph nodes triggers NOD2 activation and contributes to T1D onset | JEM
... as Card9-deficient mice exhibit defects in p38 MAP kinase and JNK activation in MDP-stimulated cells, whereas NF-κb activation ... It has been shown by in vitro experiments that Rip2−/− cells stimulated with MDP still activate JNK1/2 and p38 MAP kinases, ... suggesting that NOD2-mediated MAP kinase activation may involve other CARD domain-containing adapter proteins (Yang et al., ... 6 B). Thus, to further assess the contribution of the gut microbiota to activating the NOD2 receptor inside the PLNs, WT mice ...
  http://jem.rupress.org/content/213/7/1223
*  Activation of the novel stress‐activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6);...
... the MAP kinase kinases MKK1 and MKK2 (also called MEK1 and MEK2) activate the ERK1 and ERK2 group of MAP kinases. ERK1 and ERK2 ... MAP) kinaseactivated protein kinase‐3, a novel substrate of CSBP p38 MAP kinase. J Biol Chem, 271, 8488-8492. ... These include four protein kinases, namely MAP kinaseactivated protein kinase2 (MAPKAP‐K2, Rouse et al., 1994) and the ... The SAP kinase kinase SKK2 (also called MKK3) activates SAPK2a (also termed p38, RK, CSBP and Mxi2). The SAP kinase kinase SKK3 ...
  http://emboj.embopress.org/content/16/12/3563
*  Table of Contents - January 15, 1996, 156 (2) | The Journal of Immunology
IL-5 activates a 45-kilodalton mitogen-activated protein (MAP) kinase and Jak-2 tyrosine kinase in human eosinophils. M E Bates ... Activation of type I protein kinase A during receptor-mediated human T lymphocyte activation. D Laxminarayana and G M Kammer ... IL-10 cooperates with TNF-alpha to activate HIV-1 from latently and acutely infected cells of monocyte/macrophage lineage. A ... pim-1 proto-oncogene expression in anti-CD3-mediated T cell activation is associated with protein kinase C activation and is ...
  http://www.jimmunol.org/content/156/2
*  Plus it
Abstract LB-A20: Novel Dual Oncogenic Target Inhibitor against Allosteric Mitogen-Activated Protein Kinase (MEK1) and ... Abstract LB-A20: Novel Dual Oncogenic Target Inhibitor against Allosteric Mitogen-Activated Protein Kinase (MEK1) and ... Both kinases phosphorylate translation initiation factor eIF4e on a conserved serine 209. eIF4E can contribute to the oncogenic ... Abstract C194: Repression of tumor survival pathways by novel and selective inhibitors of MNK1 and MNK2 kinases in cancer. ...
  http://mct.aacrjournals.org/content/14/12_Supplement_2/C194
*  Interleukin 31 - Wikipedia
When IL-31 binds to the receptor complex, JAK kinases are activated which phosphorylate and activate STAT1, STAT3, and STAT5. ... Interleukin 31 is an inflammatory cytokine produced by activated CD4+ T lymphocytes, in particular activated TH2 helper cells, ... These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways. IL-31 is a cytokine with an ... Through Shc, the RAS/RAF/MEK/ERK pathway is activated along with the p38 and JNK pathways. When IL-31 binds to the IL-31RA/OSMR ...
  https://en.wikipedia.org/wiki/Interleukin_31
*  MAP3K8 - Wikipedia
MAP3K8 mitogen-activated protein kinase kinase kinase 8". Arthur JS, Ley SC (Sep 2013). "Mitogen-activated protein kinases in ... a novel MAP kinase kinase kinase". The EMBO Journal. 15 (4): 817-26. PMC 450280 . PMID 8631303. Ballester A, Tobeña R, Lisbona ... Mitogen-activated protein kinase kinase kinase 8 is an enzyme that in humans is encoded by the MAP3K8 gene. This gene was ... This kinase was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This kinase was also ...
  https://en.wikipedia.org/wiki/MAP3K8
*  Protocols and Video Articles Authored by Vincent Prinz
Pituitary Adenylate Cyclase-activating Polypeptide is Up-regulated in Cortical Pyramidal Cells After Focal Ischemia and ... Jun, 2014 , Pubmed ID: 24335820 FLOW 800 delivers a color-coded map for snapshot visualization of the temporal distribution ... Feb, 2008 , Pubmed ID: 18098126 Microglia is activated by brain injury. They migrate in response to ATP and although adenosine ... These data indicate that MMP-14 expression is not a general marker for activated microglia/macrophages but is upregulated in ...
  https://www.jove.com/author/Vincent_Prinz
*  Plus it
Inhibition of HSP27 phosphorylation by kinase-specific inhibitors and siRNA-mediated knock-down of the MAP kinase-activated ... Interestingly, the induction of HSP27 phosphorylation in GSTP1-ve cells was independent of HSP27 upstream kinase activation and ... Abstract SY14-03: Anaplastic lymphoma kinase (ALK): Normal biology and role in hematopoietic malignancies ... Using 2-D native/SDS-PAGE, the level of large (,200 kD) oligomeric HSP27 species was increased in GSTP1+ve, relative to GSTP1- ...
  http://cancerres.aacrjournals.org/content/71/8_Supplement/703
*  MAPK14 - Wikipedia
In addition, one substrate of p38 MAPK, MAP kinase-activated protein kinase 2 (MAPAK2 or MK2) can modulate and direct p38α MAPK ... The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple ... "Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase". Proceedings of the National ... "Cell type-specific inhibition of the ETS transcription factor ER81 by mitogen-activated protein kinase-activated protein kinase ...
  https://en.wikipedia.org/wiki/MAPK14