Cathepsin S Is Required for Murine Autoimmune Myasthenia Gravis Pathogenesis | The Journal of Immunology
Because presentation of acetylcholine receptor (AChR) peptides to T cells is critical to the development of myasthenia gravis, ... of AChR per mouse was determined according to previously published methods and expressed in picomoles of α-bungarotoxin (α-BT) ... Mapping myasthenia gravis-associated T cell epitopes on human acetylcholine receptors in HLA transgenic mice. J. Clin. Invest. ... Association of HLA-B8, Drw3 and anti-acetylcholine receptor antibodies in myasthenia gravis. Tissue Antigens 12:381. ...http://www.jimmunol.org/content/174/3/1729.full
086001: Myasthenia Gravis Profile With Reflex | LabCorp
Acetylcholine Receptor (AChR)-binding Antibodies. *Acetylcholine Receptor (AChR)-binding Antibodies With Reflex to AChR- ... Antibodies to alpha-bungarotoxin may sometimes be found in patients treated with snake venom. Recently administered ... Clinical correlations of antibodies that bind, block, or modulate human acetylcholine receptors in myasthenia gravis. Ann N Y ... Rhabdomyosarcoma cell line can be used for the isolation of soluble acetylcholine receptor for assaying blocking and modulating ...https://www.labcorp.com/test-menu/31661/myasthenia-gravis-profile-with-reflex
Human Nicotinic Acetylcholine Receptor alpha 7 peptide (ab24285)
Buy our Human Nicotinic Acetylcholine Receptor alpha 7 peptide. Ab24285 is a blocking peptide for ab23832 and has been ... The channel is blocked by alpha-bungarotoxin.. * Sequence similarities. Belongs to the ligand-gated ion channel (TC 1.A.9) ... Human Nicotinic Acetylcholine Receptor alpha 7 peptide. See all Nicotinic Acetylcholine Receptor alpha 7 proteins and peptides ... Suitability of Nicotinic Acetylcholine Receptor a7 and Muscarinic Acetylcholine Receptor 3 Antibodies for Immune Detection: ...http://www.abcam.com/human-nicotinic-acetylcholine-receptor-alpha-7-peptide-ab24285.html
Mice Deficient in the α7 Neuronal Nicotinic Acetylcholine Receptor Lack α-Bungarotoxin Binding Sites and Hippocampal Fast...
1994) Neuronal acetylcholine receptors that bind α-bungarotoxin mediate neurite retraction in a calcium-dependent manner. J ... 1994) Neuronal acetylcholine receptors that bind α-bungarotoxin with high affinity function as ligand-gated ion channels. ... 1997) The alpha-bungarotoxin-binding nicotinic acetylcholine receptor from rat brain contains only the alpha7 subunit. J Biol ... 1996) Synaptic currents generated by neuronal acetylcholine receptors sensitive to α-bungarotoxin. Neuron 17:1231-1240. ...http://www.jneurosci.org/content/17/23/9165
Effects of Eserine and Neostigmine on the Interaction of α-Bungarotoxin with Aplysia Acetylcholine Receptors | Molecular...
Effects of Eserine and Neostigmine on the Interaction of α-Bungarotoxin with Aplysia Acetylcholine Receptors. DAVID O. ... Effects of Eserine and Neostigmine on the Interaction of α-Bungarotoxin with Aplysia Acetylcholine Receptors. DAVID O. ... Effects of Eserine and Neostigmine on the Interaction of α-Bungarotoxin with Aplysia Acetylcholine Receptors. DAVID O. ... Binding of [125I]α-bungarotoxin to acetylcholine receptors of ganglionic homogenate of the marine mollusc Aplysia is blocked by ...http://molpharm.aspetjournals.org/content/12/6/999
Strychnine: A Potent Competitive Antagonist of α-Bungarotoxin-Sensitive Nicotinic Acetylcholine Receptors In Rat Hippocampal...
acetylcholine. nAChR. nicotinic acetylcholine receptor. α-BGT. α-bungarotoxin. CNS. central nervous system. GABA. γ-amino ... 1995) Nicotinic acetylcholine receptors. in Handbook of Receptors and Ion Channels, ed North AR (CRC, Ann Arbor, MI), pp 153- ... Strychnine: A Potent Competitive Antagonist of α-Bungarotoxin-Sensitive Nicotinic Acetylcholine Receptors In Rat Hippocampal ... Strychnine: A Potent Competitive Antagonist of α-Bungarotoxin-Sensitive Nicotinic Acetylcholine Receptors In Rat Hippocampal ...http://jpet.aspetjournals.org/content/284/3/904
Satya-Murti S[au] - PubMed - NCBI
Letter: Acetylcholine receptors and alpha-bungarotoxin.. Satya-Murti S.. Arch Ophthalmol. 1976 Feb;94(2):339. No abstract ...https://www.ncbi.nlm.nih.gov/pubmed?access_num=Satya-Murti+S&link_type=AUTHORSEARCH&cmd=search&term=Satya-Murti+S%5Bau%5D&dispmax=50
Spontaneous openings of the acetylcholine receptor channel. - Semantic Scholar
Treatment of the cells with alpha-bungarotoxin blocked the spontaneous channel currents. To determine whether the spontaneous ... These experiments indicate that the acetylcholine receptor briefly and infrequently fluctuates into an active state in the ... Agonist activation of the receptor presumably accelerates this spontaneously occurring process. ... openings were caused by an endogenous agent with cholinergic activity a reactive disulfide bond near the receptor binding site ...https://www.semanticscholar.org/paper/Spontaneous-openings-of-the-acetylcholine-receptor-Jackson/eb511a6a63967a51eab2ca826cc7c031bb15ed40
Probes for Neurotransmitter Receptors-Section 16.2 | Thermo Fisher Scientific - JP
Molecular Probes offers fluorescently labeled and unlabeled ligands for various cellular receptors, ion channels and ion ... fluorescent receptor ligands can provide a sensitive means of identifying and localizing some of the most pivotal molecules in ... Because receptor-mediated signal transduction underlies much of what occurs in cellular biochemistry and physiology, ... α-Bungarotoxin Probes for Nicotinic Acetylcholine Receptors Fluorescent α-Bungarotoxins. Nicotinic acetylcholine receptors ( ...https://www.thermofisher.com/jp/en/home/references/molecular-probes-the-handbook/probes-for-endocytosis-receptors-and-ion-channels/probes-for-neurotransmitter-receptors.html
Nicotinic acetylcholine receptor expression by directionally selective ganglion cells | Visual Neuroscience | Cambridge Core
Nicotinic acetylcholine receptor expression by directionally selective ganglion cells - Volume 24 Issue 4 - CHRISTIANNE E. ... Rabbit retinal ganglion cell responses mediated by alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors. Visual ... Contributions of GABAA receptors and GABAC receptors to acetylcholine release and directional selectivity in the rabbit retina ... Lindstrom, J.M. (1996). Neuronal nicotinic acetylcholine receptors. In Ion Channels, Vol. 4, ed. Narahashi, T., pp. 377-449. ...https://www.cambridge.org/core/journals/visual-neuroscience/article/nicotinic-acetylcholine-receptor-expression-by-directionally-selective-ganglion-cells/32C9A0906E66E744C3ABA2A4D9C80B28
α7 Nicotinic Acetylcholine Receptors Occur at Postsynaptic Densities of AMPA Receptor-Positive and -Negative Excitatory...
1994) Neuronal acetylcholine receptors that bind α-bungarotoxin with high affinity function as ligand-gated ion channels. ... 1998b) Synaptic potentials mediated via alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal ... α7 Nicotinic Acetylcholine Receptors Occur at Postsynaptic Densities of AMPA Receptor-Positive and -Negative Excitatory ... α7 Nicotinic Acetylcholine Receptors Occur at Postsynaptic Densities of AMPA Receptor-Positive and -Negative Excitatory ...http://www.jneurosci.org/content/22/12/5001
Mike Evans - Keele University
Confocal imaging of alpha-bungarotoxin-tagged acetylcholine receptors in outer hair cells. International Journal of Audiology. ... Conductance properties of the acetylcholine receptor current of guinea pig outer hair cells. J Assoc Res Otolaryngol, vol. 12(1 ... Conductance properties of the acetylcholine receptor current of guinea pig outer hair cells. J Assoc Res Otolaryngol, vol. 12(1 ... The influence of external calcium concentration on the acetylcholine receptor current in mammalian outer hair cells. British ...https://www.keele.ac.uk/lifesci/people/mikeevans/
ALD muscles at E18 were double-labeled for NRG (183N) and acetylcholine receptors (α-bungarotoxin; BTX) to localize synapses. ... 1993) ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family. Cell 72:801-815. ... 1997) Maintenance of acetylcholine receptor number by neuregulins at the neuromuscular junction in vivo. Science 276:599-603. ... 1984) Acetylcholine receptor aggregation parallels the deposition of a basal lamina proteoglycan during development of the ...http://www.jneurosci.org/content/22/6/2206
1998) Synaptic potentials mediated via α-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal ... 1989) Beta3: A new member of nicotinic acetylcholine receptor gene family is expressed in brain. J Biol Chem 264:6268-6272. ... 1998) Nicotinic acetylcholine receptor-targeted compounds: a summary of the developmental pipeline and therapeutic potential. ... 1998) The neuronal alpha6 subunit forms heteromeric acetylcholine receptors in human transfected cells. Eur J Neurosci 10:172- ...http://www.jneurosci.org/content/20/8/2783
Frontiers | Cholinergic Modulation of Cortical Microcircuits Is Layer-Specific: Evidence from Rodent, Monkey and Human Brain |...
During behaviour, activation of muscarinic and nicotinic acetylcholine receptors (mAChRs and nAChRs) by ACh alters the ... During behaviour, activation of muscarinic and nicotinic acetylcholine receptors (mAChRs and nAChRs) by ACh alters the ... Acetylcholine (ACh) signaling shapes neuronal circuit development and underlies specific aspects of cognitive functions and ... Acetylcholine (ACh) signaling shapes neuronal circuit development and underlies specific aspects of cognitive functions and ...https://www.frontiersin.org/articles/10.3389/fncir.2017.00100/full
Identity, developmental restriction and reactivity of extralaminar cells capping mammalian neuromuscular junctions | Journal of...
Acetylcholine receptors were counterstained with fluorescent bungarotoxin (pseudocoloured blue). (B) Co-immunostaining of rat ...http://jcs.biologists.org/content/121/23/3901.supplemental
Potentiation of α7-Containing Nicotinic Acetylcholine Receptors by Select Albumins | Molecular Pharmacology
1994) Neuronal acetylcholine receptors that bind α-bungarotoxin with high affinity function as ligand-gated ion channels. ... 1995) Novel subpopulation of neuronal acetylcholine receptors among those binding α-bungarotoxin. Mol Pharmacol 47:717-725. ... 2000) Expression and channel properties of α-bungarotoxin-sensitive acetylcholine receptors on chick ciliary and choroid ... nicotinic acetylcholine receptor. NMDA. N-methyl-d-aspartate. PACAP. pituitary adenylyl cyclase-activating protein. E. ...http://molpharm.aspetjournals.org/content/63/2/419.long
Regulation of GABAergic Inputs to CA1 Pyramidal Neurons by Nicotinic Receptors and Kynurenic Acid | Journal of Pharmacology and...
nicotinic acetylcholine receptor. α-BGT. α- bungarotoxin. ACSF. artificial cerebrospinal fluid. ANOVA. analysis of variance. ... 1998) Synaptic potentials mediated via α-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal ... Intraventricular administration of the α7 nicotinic acetylcholine receptor (nAChR) antagonist α-bungarotoxin (α-BGT) to rats ... Impaired α7 nicotinic acetylcholine receptor (nAChR) function and GABAergic transmission in the hippocampus and elevated brain ...http://jpet.aspetjournals.org/content/341/2/500
ProbesOnline-Acoustic focusing cytometer, visualizing autophagy, antibody selection tool | Thermo Fisher Scientific - CL
488 dye labeling of bungarotoxin-labeled acetylcholine receptors. (A) Alexa Fluor® 488 dye-bungarotoxin and (B) Qdot® 655 ... 655 nanocrystals bound to biotinylated α-bungarotoxin can be used to visualize and track individual acetylcholine receptors on ... Geng L, Zhang HL, Peng HB (2009) The formation of acetylcholine receptor clusters visualized with quantum dots. BMC Neurosci 10 ... While hot spots of clustered receptors can be seen in both images, only the diffuse, individual receptors were detected with ...https://www.thermofisher.com/cl/en/home/references/newsletters-and-journals/probesonline/probesonline-issues-2010/probesonline-april-2010.html
mediaTUM - Medien- und Publikationsserver
Acetylcholine receptors were quantitated using 125I-alpha-bungarotoxin. alpha1 -Acid glycoprotein concentrations in the serum ... Unbound plasma concentrations of atracurium to achieve 50% depression, as well as the expression of acetylcholine receptors, ... Systemic inflammation leads to resistance to atracurium without increasing membrane expression of acetylcholine receptors. ... acid glycoprotein and is unrelated to changes in acetylcholine receptor expression. «. BACKGROUND: Systemic inflammation may be ...http://mediatum.ub.tum.de/674593
Behavioral Characterization of Knockin Mice with Mutations M287L and Q266I in the Glycine Receptor α1 Subunit | Journal of...
1998) Strychnine: a potent competitive antagonist of α-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat ... nicotinic acetylcholine receptor. NMDA. N-methyl-d-aspartic acid. PTZ. pentylenetetrazole. Org 25935. cis-N-methyl-N-(6-methoxy ... 2003) α4 β2* Nicotinic acetylcholine receptors modulate the effects of ethanol and nicotine on the acoustic startle response. ... glycine receptor. BEC. blood ethanol concentration. CTA. conditioned taste aversion. EtOH. ethanol. HIC. handling-induced ...http://jpet.aspetjournals.org/content/340/2/317.long
Neuromuscular transmission in experimental autoimmune myasthenia gravis (EAMG) | SpringerLink
... was induced in rats by immunization with acetylcholine receptor (AChR) purified from the electroplax of Torpedo californica. 35 ... Inhibition of α-bungarotoxin binding to acetylcholine receptors. Science 186:55-57Google Scholar ... I. Immunogenicity of syngeneic muscle acetylcholine receptor and quantitative extraction of receptor and antibody-receptor and ... Heinemann S, Bevan S, Kullberg R, Lindstrom SJ, Rice J (1977) Modulation of acetylcholine receptor by anti-receptor antibody. ...https://link.springer.com/article/10.1007/BF00590199
Table of Contents - December 01, 1985, 13 (6) | Biochemical Society Transactions
Comparison of the effects of neosurugatoxin and α-bungarotoxin on nicotinic acetylcholine receptors in rat brain CATHERINE M. ... Purification of the muscarinic acetylcholine receptor from rat forebrain CHRISTOPHER P. BERRIE, NIGEL J. M. BIRDSALL, HARJIT K. ... 5-Hydroxytryptamine receptors in rat cerebrum CHRISTINE M. BROWN, ALISON C. DYE, KIM GOODWIN, ANDREW T. KILPATRICK, ROGER L. ... Receptor-mediated endocytosis in the isolated perfused rat liver: inhibition by dansylcadaverine AMAL AL-QUESY, C. G. CURTIS, G ...http://www.biochemsoctrans.org/content/13/6
A peptide derived from acetylcholinesterase induces neuronal cell death: characterisation of possible mechanisms | SpringerLink
... exhibits functions unrelated to the catalysis of acetylcholine (ACh) in particular during development. Although the underlying ... Pugh PC, Berg DK (1994) Neuronal acetylcholine receptors that bind α-bungarotoxin mediate neurite retraction in a calcium- ... Chan J, Quik M (1993) A role for the nicotinic α-bungarotoxin receptor in neurite outgrowth in PC12 cells. Neuroscience 56:441- ... Neurotoxicity of channel mutations in heterologously expressed α7-nicotinic acetylcholine receptor. Eur J Neurosci 13:1849-1860 ...https://link.springer.com/article/10.1007%2Fs00221-003-1567-5
Number and Density of AMPA Receptors in Individual Synapses in the Rat Cerebellum as Revealed by SDS-Digested Freeze-Fracture...
1974) Localization of acetylcholine receptor by 125I-labeled α-bungarotoxin binding at mouse motor endplates. Proc Natl Acad ... Plasticity of Signaling by Spinal Estrogen Receptor α, κ-Opioid Receptor, and Metabotropic Glutamate Receptors over the Rat ... 1250 receptors/μm2) (Nusser et al., 1997) but lower than that of nicotinic acetylcholine receptors in neuromuscular junction (, ... 2003) New role of δ2-glutamate receptors in AMPA receptor trafficking and cerebellar function. Nat Neurosci 6:869-876. ...http://www.jneurosci.org/content/27/8/2135