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*  Drug overdose - Wikipedia
Among Poly drug use (F19) Drug "cocktails" (Speedballs) Medications Aspirin poisoning (T39.0) Acetaminophen poisoning (Alone or ... List of deaths from drug overdose and intoxication Responsible drug use Suicide methods ยง Drug overdose Water intoxication ... Drug overdose was the leading cause of injury death in 2013. Among people 25 to 64 years old, drug overdose caused more deaths ... The term drug overdose (or simply overdose or OD) describes the ingestion or application of a drug or other substance in ...
  https://en.wikipedia.org/wiki/Drug_overdose
*  Cheese (recreational drug) - Wikipedia
... abuse and overdose of cheese are more dangerous than pure-form opiate overdoses. Emergency personnel must address the overdose ... The acetaminophen content of the drug induces severe, irreversible damage to the liver when taken in high doses for long ... As of 2012 the drug use is now among older people who were teenagers around the period the drug was first discovered. Cheese is ... Some toxicologists questioned the results due to the absence of acetaminophen. Other experts argued that acetaminophen has a ...
  https://en.wikipedia.org/wiki/Cheese_(recreational_drug)
*  Nonsteroidal anti-inflammatory drug - Wikipedia
Wilkes JM, Clark LE, Herrera JL (November 2005). "Acetaminophen overdose in pregnancy". Southern Medical Journal. 98 (11): 1118 ... Nonsteroidal anti-inflammatory drugs (NSAIDs) are a drug class that groups together drugs that reduce pain, decrease fever, and ... Colebatch, AN (2011). "Safety of non-steroidal anti-inflammatory drugs, including aspirin and paracetamol (acetaminophen) in ... Moore DE (2002). "Drug-induced cutaneous photosensitivity: incidence, mechanism, prevention and management". Drug Safety. 25 (5 ...
  https://en.wikipedia.org/wiki/Nonsteroidal_anti-inflammatory_drug
*  Derek Boogaard - Wikipedia
He died at 28 from an accidental drug and alcohol overdose while recovering from a concussion. A posthumous examination of his ... "Percocet oxycodone and acetaminophen tablets USP" (PDF). Endo Pharmaceuticals. May 2011. Archived from the original (PDF) on ... Biography portal Ice hockey portal Minnesota portal Saskatchewan portal List of deaths from drug overdose and intoxication List ... Len Boogaard, now in a desk job with the RCMP, has been investigating his son's drug use when he can, trying to see which of ...
  https://en.wikipedia.org/wiki/Derek_Boogaard
*  Combined drug intoxication - Wikipedia
The problem is with paracetamol (acetaminophen/Tylenol for example ) overdose and liver damage. These two drugs, in combination ... Adverse drug reaction Drug interaction List of deaths from drug overdose and intoxication People referred to as "Doctor ... Drug Interactions Checker at Drugs.com: Drug Information Online Drug Interaction Checker at Medscape (registration required). ... with other drugs like Nyquil and Theraflu, can cause death by multiple drug intake and/or drug overdose. Another solution would ...
  https://en.wikipedia.org/wiki/Combined_drug_intoxication
*  Paracetamol poisoning - Wikipedia
One strategy for reducing harm done by acetaminophen overdoses is selling paracetamol pre-combined in tablets either with an ... A drug nomogram developed in 1975, called the Rumack-Matthew nomogram, estimates the risk of toxicity based on the serum ... acetaminophen). Most people have few or non-specific symptoms in the first 24 hours following overdose. This may include ... Acute paracetamol overdose in children rarely causes illness or death, and it is very uncommon for children to have levels that ...
  https://en.wikipedia.org/wiki/Paracetamol_poisoning
*  Overmedication - Wikipedia
For example, overmedication[dubious - discuss] (in the form of acute overdose) can occur when a prescription drug like Vicodin ... which contains acetaminophen as the active ingredient. In other words, overmedication can be caused by both prescribers and ... While these drugs can provide relief from some symptoms the children may suffer, psychiatric drugs have been shown in some ... Drug companies have benefited considerably with profits made in sales for drugs such as stimulants for hyperactive children, ...
  https://en.wikipedia.org/wiki/Overmedication
*  Paracetamol - Wikipedia
Food and Drug Administration launched a public education program to help consumers avoid overdose, warning: "Acetaminophen can ... Kidney damage is seen in rare cases, most commonly in overdose. On August 2, 2013, the U.S. Food and Drug Administration (FDA) ... Paracetamol toxicity is the foremost cause of acute liver failure in the Western world and accounts for most drug overdoses in ... Patents on paracetamol have long expired, and generic versions of the drug are widely available. Acetaminophen is the name ...
  https://en.wikipedia.org/wiki/Paracetamol
*  Dextropropoxyphene - Wikipedia
The drug has been taken off the market in Europe and the US due to concerns of fatal overdoses and heart arrhythmias. Its onset ... "Analgesic efficacy of tramadol/acetaminophen and propoxyphene/acetaminophen for relief of postoperative wound pain". Acta ... Additionally, patients have not substituted other drugs as a method of overdose. The decision to withdraw coproxamol has met ... Its withdrawal from the UK market is a result of concerns relating to its toxicity in overdose (even small overdoses can be ...
  https://en.wikipedia.org/wiki/Dextropropoxyphene
*  Hepatotoxicity - Wikipedia
In acetaminophen toxicity, however, the initial insult can be fatal. Fulminant hepatic failure from drug-induced hepatotoxicity ... As in the case of acetaminophen overdose, this type of injury occurs shortly after some threshold for toxicity is reached. ... Drug metabolism is usually divided into two phases: phase 1 and phase 2. Phase 1 reaction is thought to prepare a drug for ... Simultaneous use of multiple drugs may add to the complexity. As in acetaminophen toxicity, well established, dose-dependent, ...
  https://en.wikipedia.org/wiki/Hepatotoxicity
*  Hydrocodone/paracetamol - Wikipedia
... which is also the main ingredient in commonly used nonprescription drugs such as Tylenol. Each year, acetaminophen overdose is ... "Acetaminophen / Hydrocodone Dosage Guide with Precautions - Drugs.com". www.drugs.com. Retrieved 2015-11-04. "Rules - 2014 - ... "FDA Drug Safety Communication: Prescription Acetaminophen Products to be Limited to 325 mg Per Dosage Unit; Boxed Warning Will ... It can be addictive and is easy to overdose on. Hydrocodone/acetaminophen is a two-ingredient combination formula consisting of ...
  https://en.wikipedia.org/wiki/Hydrocodone/paracetamol
*  Oxycodone - Wikipedia
Equianalgesic Froehde reagent Illegal drug trade List of deaths from drug overdose and intoxication Psychoactive drug Kalso E ( ... Some of the cases were due to overdoses of the acetaminophen component, resulting in fatal liver damage. Reformulated OxyContin ... Oxycodone is a Class A drug under the Misuse of Drugs Act. For Class A drugs, which are "considered to be the most likely to ... Oxycodone is listed as a Class A drug in the Misuse of Drugs Act of Singapore, which means offences in relation to the drug ...
  https://en.wikipedia.org/wiki/Oxycodone
*  Oxycodone/paracetamol - Wikipedia
In 2015, nearly two-thirds of drug overdoses were linked to opioids like Percocet, OxyContin, heroin, and fentanyl. [...] ... Center for Drug Evaluation and Research. Retrieved 2009-03-30. "Percocet oxycodone and acetaminophen tablets USP" (PDF). Endo ... "Drugs@FDA. FDA approved drug products (searchable database)". U.S. Food and Drug Administration, ... In 2015, 27 million people reported current use of illegal drugs or abuse of prescription drugs. Despite this self-reporting, ...
  https://en.wikipedia.org/wiki/Oxycodone/paracetamol
*  NAPQI - Wikipedia
The prognosis is good for paracetamol overdoses if treatment is initiated up to 8 hours after the drug has been taken. Most ... acetaminophen). It is normally produced only in small amounts, and then almost immediately detoxified in the liver. However, ... In general, however, the primary concern is accidental or intentional paracetamol overdose. Since the drug is available over ... A small amount of the drug is metabolized via the cytochrome P-450 pathway (to be specific, CYP3A4 and CYP2E1) into NAPQI, ...
  https://en.wikipedia.org/wiki/NAPQI
*  Drug intolerance - Wikipedia
... resulting in an overdose-a "normal" dose can be a "toxic" dose in these individuals, leading to clinically significant effects ... after a normal dose of acetaminophen Fatal poisoning in a breastfed newborn baby due to normal use of codeine by the mother. ... Some instances of drug intolerance are known to result from genetic variations in drug metabolism. Drugs in systemic ... Adverse drug reaction Contraindication DRESS syndrome (drug hypersensitivity syndrome) Drug tolerance Food intolerance Jennedy ...
  https://en.wikipedia.org/wiki/Drug_intolerance
*  Lacing (drugs) - Wikipedia
Less common drugs in ecstasy include diphenhydramine, acetaminophen, 5-MeO-DiPT, 2C-B, procaine, and phencyclidine (PCP). ... The emergence of fentanyl-laced cocaine has led to an increase in cocaine overdose fatalities in New York City. Though ... Date rape drug Mickey Finn (drugs) Pill testing Cutting agent Darknet market Meth-laced pot a huge problem, experts say Canada. ... It is possible that drug users may accidental purchase a product without knowing that it had been laced with a more potent drug ...
  https://en.wikipedia.org/wiki/Lacing_(drugs)
*  Doxylamine - Wikipedia
The carcinogenicity of the drug in humans is not well studied, and the IARC lists the drug as "not classifiable as to its ... Rarely, an overdose results in rhabdomyolysis and acute renal failure. Studies of doxylamine's carcinogenicity in mice and rats ... Doxylamine is also used in combination with the analgesics paracetamol (acetaminophen) and codeine as an analgesic/calmative ... The drug is also acts as an antagonist of the muscarinic acetylcholine receptors to a lesser extent. This action is responsible ...
  https://en.wikipedia.org/wiki/Doxylamine
*  Toxication - Wikipedia
Hepatotoxicity indicates the drug's toxicity to liver. Paracetamol (acetaminophen, APAP) is converted into the hepatotoxic ... In the case of overdoses, the storage of GSH will not be enough for NAPQI detoxication, thereby resulting in acute liver injury ... While the parent drug are usually less active, both the parent drug and its metabolite can be chemically active and cause ... The unusual level of activity CYP450 enzymes might lead to the changes in drug metabolism and convert drugs into their more ...
  https://en.wikipedia.org/wiki/Toxication
*  Kidney failure - Wikipedia
Drug overdoses, accidental or from chemical overloads of drugs such as antibiotics or chemotherapy, may also cause the onset of ... Overuse of common drugs such as ibuprofen, and acetaminophen (paracetamol) can also cause chronic kidney disease. Some ... "Risk of Kidney Failure Associated with the Use of Acetaminophen, Aspirin, and Nonsteroidal Antiinflammatory Drugs". New England ...
  https://en.wikipedia.org/wiki/Kidney_failure
*  Meprobamate - Wikipedia
BEHAVIOR' DRUGS NOW ENVISIONED; Aldous Huxley Predicts They Will Bring Re-Examining of Ethics and Religion". The New York Times ... Death has been reported with ingestion of as little as 12 g of meprobamate and survival with as much as 40 g. In an overdose, ... It is also found as a component of the combination analgesic "Stopayne" capsules (along with paracetamol (acetaminophen), ... In the mid-1940s, Frank Milan Berger was working in a laboratory of a British drug company, looking for a preservative for ...
  https://en.wikipedia.org/wiki/Meprobamate
*  Recreational drug use - Wikipedia
High dosages taken to induce recreational drug effects may lead to overdoses. Antihistamines are also consumed in combination ... also known in the US as acetaminophen), the nonsteroidal anti-inflammatory drugs (NSAIDs) such as the salicylates, and opioid ... Counterfeit drug Demand reduction Drug education Gateway drug theory Entheogen Harm reduction Illegal drug trade Prohibition ( ... These drugs are not without their own particular risks. The concept of "responsible drug use" is that a person can use drugs ...
  https://en.wikipedia.org/wiki/Recreational_drug_use
*  Carisoprodol - Wikipedia
In recreational drug users, deaths have resulted from carelessly combining overdoses of hydrocodone and carisoprodol. Another ... Compounded tablets with acetaminophen are also available. Federally, carisoprodol is a Prescription Drug (Schedule I, sub- ... Drug information Carisoprodol, el soma de nuestro tiempo (in Spanish) Drug information for Patients, Drug information for ... Meprobamate and other muscle-relaxing drugs often were subjects of misuse in the 1950s and 60s. Overdose cases were reported as ...
  https://en.wikipedia.org/wiki/Carisoprodol
*  Pain management - Wikipedia
Paracetamol (acetaminophen), or a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen. Paracetamol, an NSAID and/or ... high doses are associated with an increased risk of opioid overdose. From the Food and Drug Administration's website: " ... The other major group of analgesics are nonsteroidal anti-inflammatory drugs (NSAID). Acetaminophen/paracetamol is not always ... Drugs such as gabapentin have been widely prescribed for the off-label use of pain control. The list of side effects for these ...
  https://en.wikipedia.org/wiki/Pain_management
*  Hydrocodone - Wikipedia
"Fatal hydrocodone overdose in a child: Pharmacogenetics and drug interactions". Pediatrics. 126 (4): e986-9. doi:10.1542/peds. ... "Acetaminophen ototoxicity after acetaminophen/hydrocodone abuse: Evidence from two parallel in vitro mouse models". ... "Drug-Related Hospital Emergency Room Visits". Retrieved 2017-08-11. Hydrocodone at U.S. National Library of Medicine: Drug ... "Drugs@FDA-Approval History: Hycodan". FDA. Retrieved 7 January 2006. "FDA Docket No. 2007N-0353, Drug Products Containing ...
  https://en.wikipedia.org/wiki/Hydrocodone
*  Glucuronic acid - Wikipedia
... with ethanol and acetaminophen being the most commonly implicated substances involved in cases of accidental overdoses which ... It is possible to exhaust the bodies supply of glucuronic acid by combining multiple drugs/substances whose metabolism and ... Neonates are deficient in this conjugating system, making them particularly vulnerable to drugs such as chloramphenicol, which ... Ethanol, morphine, paracetamol (acetaminophen), cyclooxygenase inhibitors (NSAIDs), endogenous steroids, and certain ...
  https://en.wikipedia.org/wiki/Glucuronic_acid