*  Three-dimensional cell growth confers radioresistance by chromatin density modification.
Xenograft Model Antitumor Assays. Chemical. Reg. No./Substance: 0/Cell Cycle Proteins; 0/Chromosomal Proteins, Non-Histone; 0/ ... cell cultures as xenografts and monolayer cell cultures were compared. Here, we show that increased levels of heterochromatin ... euchromatin to heterochromatin-associated DSBs were equally distributed in irradiated 3D cell cultures and xenograft tumors, ...
  http://www.biomedsearch.com/nih/Three-Dimensional-Cell-Growth-Confers/20442295.html
*  Preclinical modeling of EGFR inhibitor resistance in head and neck cancer.
Xenograft Model Antitumor Assays. Grant Support. ID/Acronym/Agency: F31DE020947/DE/NIDCR NIH HHS; P30CA047904/CA/NCI NIH HHS; ... We attempted to generate models of cetuximab resistance in HNSCC cell line-derived xenografts and heterotopic tumorgrafts ... While all 10 HNSCC cell line xenografts tested were sensitive to cetuximab in vivo, heterotopic patient tumorgrafts varied in ... 25176024 - In vitro modeling of her2-targeting therapy in disseminated prostate cancer.. 2640294 - Investigations on ...
  http://www.biomedsearch.com/nih/Preclinical-modeling-EGFR-inhibitor-resistance/22785204.html
*  Inhibition of melanoma development in the Nras((Q61K)) ::Ink4a(-/-) mouse model by the small molecule BI-69A11.
Xenograft Model Antitumor Assays. ras Proteins / genetics*. Grant Support. ID/Acronym/Agency: CA099961/CA/NCI NIH HHS; CA128814 ... Disease Models, Animal. Gene Expression Regulation, Neoplastic / drug effects. Humans. Injections, Intraperitoneal. Ki-67 ... Inhibition of melanoma development in the Nras((Q61K)) ::Ink4a(-/-) mouse model by the small molecule BI-69A11. ... of the tumors in this model. BI-69A11-resistant Nras((Q61K)) ::Ink4a(-/-) tumors exhibited increased CD45 expression, ...
  http://www.biomedsearch.com/nih/Inhibition-melanoma-development-in-Nras/23035722.html
*  AMFR and NOTCH1 are the direct target genes of miR-139- | Open-i
A) Initial screening of miR-139-5p target genes using a microarray assay, bioinformatics predictions ... Xenograft Model Antitumor Assays. Related in: MedlinePlus. © Copyright Policy - OpenAccess Related In: Results - Collection ... D) The protein levels of AMFR and NOTCH1 were determined by Western blot assays using LoVo and HCT-116 cells transfected with ... D) The protein levels of AMFR and NOTCH1 were determined by Western blot assays using LoVo and HCT-116 cells transfected with ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4225484_13238_2014_93_Fig3_HTML&req=4
*  In vivo AZD1480 treatment negatively impacts on the sup | Open-i
Xenograft Model Antitumor Assays. Related in: MedlinePlus. © Copyright Policy - open-access Related In: Results - Collection ... Here we investigated the effects of AZD1480 on the function of different immune cell populations in a melanoma model. When MO4 ... Here we investigated the effects of AZD1480 on the function of different immune cell populations in a melanoma model. When MO4 ... AZD1480 delays tumor growth in a melanoma model while enhancing the suppressive activity of myeloid-derived suppressor cells. ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4196164_oncotarget-05-6801-g004&req=4
*  A and B Pralatrexate is effective against H2052 xenogra | Open-i
A and B Pralatrexate is effective against H2052 xenografts. Mice bearing 100 mm3 tumors were treated by i.p injection of saline ... Xenograft Model Antitumor Assays*. Minor. *Aminopterin/administration & dosage/analogs & derivatives/pharmacology. *Animals ... Fig3: A and B Pralatrexate is effective against H2052 xenografts. Mice bearing 100 mm3 tumors were treated by i.p injection of ... Fig3: A and B Pralatrexate is effective against H2052 xenografts. Mice bearing 100 mm3 tumors were treated by i.p injection of ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4209237_280_2014_2580_Fig3_HTML&req=4
*  RGB-286638 Mediated p53-Independent Apoptosis in MM Cel | Open-i
Xenograft Model Antitumor Assays. Related in: MedlinePlus. © Copyright Policy Related In: Results - Collection ... and viability was assayed using MTT. Data represent means (+/−SD) of triplicate cultures. P53 and p-RNAPII S2 were examined by ... and viability was assayed using MTT. Data represent means (+/−SD) of triplicate cultures. P53 and p-RNAPII S2 were examined by ... are of particular interest due to their potent antitumor activity independent of p53 gene alterations. P53 deletion is ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3928098_nihms549930f5&req=4
*  embryonal carcinoma of testis diagnosis drug therapy 2000:2010[pubdate] *count=100 - BioMedLib™ search engine
Xenograft Model Antitumor Assays. *Genetic Alliance. consumer health - Testicular cancer.. *MedlinePlus Health Information. ... NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .. *[Source] The source of this record is MEDLINE®, a database of the U.S. ... NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .. *[Source] The source of this record is MEDLINE®, a database of the U.S. ... NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .. *NCI CPTC Antibody Characterization Program. NCI CPTC Antibody ...
  http://www.bmlsearch.com/?kwr=embryonal+carcinoma+of+testis+diagnosis+drug+therapy+2000:2010%5Bpubdate%5D&cxts=100&stmp=b1
*  melanoma of the cornea drug therapy 2000:2010[pubdate] *count=100 - BioMedLib™ search engine
Xenograft Model Antitumor Assays. *COS Scholar Universe. author profiles.. *NCI CPTAC Assay Portal. NCI CPTAC Assay Portal . ... NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .. *[Source] The source of this record is MEDLINE®, a database of the U.S. ... NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .. *[Email] Email this result item Email the results to the following email ... NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .. *[Email] Email this result item Email the results to the following email ...
  http://www.bmlsearch.com/?kwr=melanoma+of+the+cornea+drug+therapy+2000:2010%5Bpubdate%5D&cxts=100&stmp=b1
*  b cell small lymphocytic lymphoma stage i 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Models, Biological. Osteoclasts / drug effects. Osteoclasts / pathology. Xenograft Model Antitumor Assays. *Genetic Alliance. ... NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .. *[Source] The source of this record is MEDLINE®, a database of the U.S. ... NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .. *[Source] The source of this record is MEDLINE®, a database of the U.S. ... NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .. *[Source] The source of this record is MEDLINE®, a database of the U.S. ...
  http://www.bmlsearch.com/?kwr=b+cell+small+lymphocytic+lymphoma+stage+i+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
*  grade iv astrocytic tumor of the brain drug therapy 2000:2010[pubdate] *count=100 - BioMedLib™ search engine
Xenograft Model Antitumor Assays. *Genetic Alliance. consumer health - Glioblastoma.. *MedlinePlus Health Information. consumer ... NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .. *[Source] The source of this record is MEDLINE®, a database of the U.S. ... NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .. *[Source] The source of this record is MEDLINE®, a database of the U.S. ... NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .. *[Email] Email this result item Email the results to the following email ...
  http://www.bmlsearch.com/?kwr=grade+iv+astrocytic+tumor+of+the+brain+drug+therapy+2000:2010%5Bpubdate%5D&cxts=100&stmp=b1
*  neoplasm of muscle of neck drug therapy 2000:2010[pubdate] *count=100 - BioMedLib™ search engine
Xenograft Model Antitumor Assays / methods. *[MeSH-minor] Animals. DNA, Neoplasm / metabolism. Female. HT29 Cells. Humans. Mice ... NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .. *[Source] The source of this record is MEDLINE®, a database of the U.S. ... Title] Distribution of 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl) uracil in mice bearing colorectal cancer xenografts: ... uracil in mice bearing colorectal cancer xenografts: rationale for therapeutic use and as a positron emission tomography probe ...
  http://www.bmlsearch.com/?kwr=neoplasm+of+muscle+of+neck+drug+therapy+2000:2010%5Bpubdate%5D&cxts=100&stmp=b1
*  Chemoresistant BCM2665 transplanted in the fat pad of S | Open-i
Xenograft Model Antitumor Assays*. Minor. *Adipose Tissue/drug effects. *Animals. *Cell Line, Tumor ... Stat3 inhibitor reduces breast cancer tumor-initiating cells and improves recurrence free survival in a human-xenograft model. ... Stat3 inhibitor reduces breast cancer tumor-initiating cells and improves recurrence free survival in a human-xenograft model. ... SEM in 4 treatment arms of the chemoresistant BCM2665 model for the treatment period of 14 days. Significant decrease in mean ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3412855_pone.0030207.g002&req=4
*  Expression of apoptosis-related genes in liver after CD | Open-i
Xenograft Model Antitumor Assays. Related in: MedlinePlus. © Copyright Policy Related In: Results - Collection ... Annexin V/PI assay demonstrated that apoptosis increased with increase in the concentration of CD-3. The expression levels of ... Annexin V/PI assay demonstrated that apoptosis increased with increase in the concentration of CD-3. The expression levels of ... The HCC tumor model was established in mice by injecting N-nitrosodiethylamine/carbon tetrachloride (NDEA/CCl4) and the effect ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3722203_pone.0068710.g010&req=4
*  ALDH activity and expression in L3.6pl pancreatic cance | Open-i
Xenograft Model Antitumor Assays. Related in: MedlinePlus. © Copyright Policy Related In: Results - Collection ... In direct xenograft tumors, the proportions of total tumor cells expressing ALDH and/or CD133 in xenograft tumors were ... In direct xenograft tumors, the proportions of total tumor cells expressing ALDH and/or CD133 in xenograft tumors were ... E) Staining for ALDH1 in sections of indirect xenograft tumors formed from L3.6pl cells in nude mice. Note small clusters of ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3113804_pone.0020636.g001&req=4
*  Characterization of the OV ZD55SP/E1A. (A) A schematic | Open-i
ZD55SP/E1A-IL-24-shMPP1 also showed excellent anti-tumour effects in vivo on SW620 xenograft nude mice.In conclusion, our ... ZD55SP/E1A-IL-24-shMPP1 also showed excellent anti-tumour effects in vivo on SW620 xenograft nude mice.In conclusion, our ... Bottom Line: Our results demonstrated excellent anti-tumour effect of ZD55SP/E1A-IL-24-shMPP1 in vitro on multiple cancer cell ... Bottom Line: Our results demonstrated excellent anti-tumour effect of ZD55SP/E1A-IL-24-shMPP1 in vitro on multiple cancer cell ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3823082_jcmm0016-1298-f3&req=4
*  ZFIN Publication: White et al., 2011
Xenograft Model Antitumor Assays; Zebrafish/embryology; Zebrafish/genetics ... DHODH inhibition led to a marked decrease in melanoma growth both in vitro and in mouse xenograft studies. Taken together, ... Disease Models, Animal; Gene Expression Regulation, Neoplastic; Genes, p53/genetics; Humans; Isoxazoles/pharmacology; ...
  http://zfin.org/ZDB-PUB-110426-15
*  Flow cytometry analysis of recombinant CEA reporter pro | Open-i
Xenograft Model Antitumor Assays. Related in: MedlinePlus. © Copyright Policy Related In: Results - Collection ... Reporter gene-transfected Jurkat xenografts in mice were analyzed by immunohistochemistry (IHC) and imaged by PET using ¹²⁴I- ... Reporter gene-transfected Jurkat xenografts in mice were analyzed by immunohistochemistry (IHC) and imaged by PET using ¹²⁴I- ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2992604_11307_2010_375_Fig2_HTML&req=4
*  Next page) Thyrosine kinase inhibitors (TKI) increases | Open-i
Next page) Thyrosine kinase inhibitors (TKI) increases levels of DNA methyltransferases (DNMT). (a) MTT assay. K562 cells were ... Xenograft Model Antitumor Assays. Related in: MedlinePlus. © Copyright Policy - open-access Related In: Results - Collection ... fig01: (Next page) Thyrosine kinase inhibitors (TKI) increases levels of DNA methyltransferases (DNMT). (a) MTT assay. K562 ... fig01: (Next page) Thyrosine kinase inhibitors (TKI) increases levels of DNA methyltransferases (DNMT). (a) MTT assay. K562 ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4317938_cas0105-0297-f1&req=4
*  A) Effect of 2DG on the proliferation of LNCaP and MCF | Open-i
... xenograft models in vivo. In mice bearing MCF-7 xenografts, daily p.o. administration of STX140 (5 mg kg(-1)) resulted in a 46 ... ATPlite plate assay. Results are expressed as percent of untreated. At this dose of 2DG, no significant inhibition of cell ... xenograft models in vivo. In mice bearing MCF-7 xenografts, daily p.o. administration of STX140 (5 mg kg(-1)) resulted in a 46 ... ATPlite plate assay. Results are expressed as percent of untreated. At this dose of 2DG, no significant inhibition of cell ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2600694_6604752f2&req=4
*  SEM image and in vitro release profile of 9NC loaded li | Open-i
Xenograft Model Antitumor Assays*. Minor. *Animals. *Apoptosis/drug effects. *Cell Cycle/drug effects ... 9NC-LP has a more potent anti-tumor effect and fewer side effects in vivo, which means it is a promising reagent for cancer ... 9NC-LP has a more potent anti-tumor effect and fewer side effects in vivo, which means it is a promising reagent for cancer ... 9NC-LP has a more potent anti-tumor effect and fewer side effects in vivo, which means it is a promising reagent for cancer ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3111480_pone.0021064.g001&req=4
*  Expression patterns of GFP-tagged proteins in tetracycl | Open-i
Xenograft Model Antitumor Assays. Related in: MedlinePlus. © Copyright Policy - open-access Related In: Results - Collection ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4385921_cddis201543f1&req=4
*  Androgen Receptor Variants Mediate DNA Repair after Prostate Cancer Irradiation.
Xenograft Model Antitumor Assays. Research team. Prostate Cancer Targeted Therapy Group. Language. eng ...
  https://repository.icr.ac.uk/handle/internal/771