Viruses | Free Full-Text | African Swine Fever Virus Ubiquitin-Conjugating Enzyme Is an Immunomodulator Targeting NF-κB...
In contrast, activation of IRF3 and ISRE signaling upon stimulation with TRIFΔRIP, cGAS/STING or RIG-I-CARD remained unaltered ... In this work, we have revealed that early viral protein UBCv1, the only known conjugating enzyme encoded by a virus, modulates ... Transient overexpression of UBCv1 impaired activation of NF-κB and AP-1 transcription factors induced by several agonists of ... is an acute and persistent swine virus with a high economic burden that encodes multiple genes to evade host immune response. ...
Table - Macrophage Activation Marker Soluble CD163 Associated with Fatal and Severe Ebola Virus Disease in Humans - Volume 25,...
Infection and activation of monocytes by Marburg and Ebola viruses. J Virol. 2001;75:11025-33. DOIPubMedGoogle Scholar ... Macrophage Activation Marker Soluble CD163 Associated with Fatal and Severe Ebola Virus Disease in Humans1 Anita K. McElroy. , ... Human Ebola virus infection results in substantial immune activation. Proc Natl Acad Sci U S A. 2015;112:4719-24. DOIPubMed ... Kreuels B, Wichmann D, Emmerich P, Schmidt-Chanasit J, de Heer G, Kluge S, et al. A case of severe Ebola virus infection ...
Bacterial Outer Membrane Vesicles Provide Broad-Spectrum Protection against Influenza Virus Infection via Recruitment and...
National planning assists in determining the actions that should be taken in the upcoming weeks, months, and years to prevent, detect, and respond to risks and threats. These actions can be identified through comprehensive tools such as all-hazards National Action Plans for Health Security (NAPHS), disease-specific plans, contingency plans, and other sources. ...
DNA sequence of the herpes simplex virus type 1 gene whose product is responsible for transcriptional activation of immediate...
Apart from its role in trans-activation, Vmw65 is a major constituent of the virion. Its possible significance in virus ... DNA sequence of the herpes simplex virus type 1 gene whose product is responsible for transcriptional activation of immediate ... Previous work has shown that transcriptional activation of herpes simplex virus type 1 (HSV-1) immediate early genes is ... DNA sequence of the herpes simplex virus type 1 gene whose product is responsible for transcriptional activation of immediate ...
Trans-activation of human immunodeficiency virus gene expression is mediated by nuclear events.
"Trans-activation of human immunodeficiency virus gene expression is mediated by nuclear events." Proceedings of the National ... "Trans-activation of human immunodeficiency virus gene expression is mediated by nuclear events." Proceedings of the National ... Trans-activation of human immunodeficiency virus gene expression is mediated by nuclear events.. Publication , Journal Article ... Trans-activation of human immunodeficiency virus gene expression is mediated by nuclear events. Proceedings of the National ...
Virus Activation | Profiles RNS
"Virus Activation" by people in this website by year, and whether "Virus Activation" was a major or minor topic of these ... "Virus Activation" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... Below are the most recent publications written about "Virus Activation" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Virus Activation". ...
Complement-Related Disorders: Background, Pathophysiology, Activation
The terminal components of the complement system result in lysis of virus-infected cells, tumor cells, and some gram-negative ... C-reactive protein (CRP, not shown) leads to classic pathway activation analogous to lectin pathway activation by MBL and ... C-reactive protein (CRP, not shown) leads to classic pathway activation analogous to lectin pathway activation by MBL and ... Sialic acid blocks activation by favoring the binding of factor H to C3b, which is then inactivated by factor I. [1] ...
Virus Activation Via Electromagnetic Field - Health Keys
The following research paper is significant as it shows that electromagnetic fields can activate viruses in human cells: https ... Virus Activation Via Electromagnetic Field. The following research paper is significant as it shows that electromagnetic fields ... What does it mean to "activate" a virus?. Keep in mind that a virus is not alive. It is just a string of RNA/DNA surrounded by ... Exposure to a 50 Hz electromagnetic field induces activation of the Epstein-Barr virus genome in latently infected human ...
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Viruses | Free Full-Text | Dendritic Cells in Oncolytic Virus-Based Anti-Cancer Therapy
We also examine how DC-OV interaction affects DC recruitment, OV delivery, and anti-tumor immunity activation. Understanding ... Many reports thus far have studied oncolytic viruses (OVs), viruses that preferentially target and kill cancer cells, for their ... vaccinia virus [160], Newcastle disease virus [161], measles virus [162], poliovirus [163], HSV [164], coxsackievirus [165], ... CDC42 Use in Viral Cell Entry Processes by RNA Viruses. Next Article in Special Issue. Newcastle Disease Virus: Potential ...
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Epstein-Barr virus ncRNA from a nasopharyngeal carcinoma induces an inflammatory response that promotes virus production |...
The non-coding RNA EBER2 of the Epstein-Barr virus M81 strain potentiates virus lytic replication in B cells by generating a ... Thus, M81 induced chronic inflammation in its target cells and this resulted in increased virus production. These observations ... induces potent spontaneous virus production in infected B cells. We found that the M81 non-coding Epstein-Barr-encoded RNA ... provide a mechanistic molecular link between M81 virus replication-a central viral function and a cancer risk factor-and the ...
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Herpesvirus quiescence in neuronal cells IV: Virus activation induced by pituitary adenylate cyclase-activating polypeptide ...
... only partially mimicked the effect of PACAP on virus activation. Taken together, PACAP induced HSV-1 activation from QIF-PC12 ... only partially mimicked the effect of PACAP on virus activation. Taken together, PACAP induced HSV-1 activation from QIF-PC12 ... only partially mimicked the effect of PACAP on virus activation. Taken together, PACAP induced HSV-1 activation from QIF-PC12 ... only partially mimicked the effect of PACAP on virus activation. Taken together, PACAP induced HSV-1 activation from QIF-PC12 ...
Neutrophil Activation and Early Features of NET Formation Are Associated With Dengue Virus Infection in Human. - Nuffield...
However, despite studies that have referred to activation of neutrophils in DENV infections, the exact roles of neutrophils ... In vitro incubation of NETs with DENV-2 virus significantly decreased DENV infectivity. Interestingly, increased levels of NET ... this confirmed in vivo neutrophil activation during DENV infection. Spontaneous decondensation of nuclei, an early event of ... The involvement of the immune system in the protection and pathology of natural dengue virus (DENV) has been extensively ...
Discovery of a small molecule Tat-trans-activation-responsive RNA antagonist that potently inhibits human immunodeficiency...
... of a small molecule Tat-trans-activation-responsive RNA antagonist that potently inhibits human immunodeficiency virus-1 ... TR87 was also shown to specifically disrupt Tat-TAR binding in vitro and inhibit Tat-mediated transcriptional activation in ... Dive into the research topics of Discovery of a small molecule Tat-trans-activation-responsive RNA antagonist that potently ... TR87 was also shown to specifically disrupt Tat-TAR binding in vitro and inhibit Tat-mediated transcriptional activation in ...
Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity<...
Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity. Proceedings ... Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity. In: ... Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity. / ... Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity. ...
Respiratory syncytial virus replication induces Indoleamine 2,3-dioxygenase (IDO) activation in human dendritic cells | Allergy...
Hematopoietic cell activation in the subventricular zone after Theiler's virus infection. - Immunology
RESULTS: CD45+ activation (inflammation) occurred early in the forebrain and preceded cerebellar and spinal cord inflammation. ... Since inflammation can reduce neurogenesis, we tested whether Theilers murine encephalomyelitis virus (TMEV) induces ... Hematopoietic cell activation in the subventricular zone after Theilers virus infection. Goings GE., Greisman A., James RE., ... RESULTS: CD45+ activation (inflammation) occurred early in the forebrain and preceded cerebellar and spinal cord inflammation. ...
A Mechanism for the Activation of the Influenza Virus Transcriptase - Oxford Particle Imaging Centre
Activation of NLRP3 Inflammasome by Virus-like Particles of Human Polyomaviruses in Macrophages | Sciety
Activation of NLRP3 Inflammasome by Virus-like Particles of Human Polyomaviruses in Macrophages. *Asta Lučiūnaitė ... Similar activation pattern was observed in primary human macrophages treated with VLPs. Single cell RNAseq analysis of THP-1 ... Inhibitors of cathepsins and K + efflux decreased IL-1β levels and cell death indicating a complex inflammasome activation ... of paramyxoviruses and spherical virus-like particles (VLPs) of human polyomaviruses. The effects of viral proteins on cell ...
Immune Consequences of in vitro Infection of Human Peripheral Blood Leukocytes with Vesicular Stomatitis Virus | Journal of...
Several viruses are capable of regulating monocyte activation and maturation leading to either immune hyperactivation or ... Virus-Specific RNA Specified by the Group I and IV Temperature-Sensitive Mutants of Vesicular Stomatitis Virus Intervirology ( ... Over the last decade, vesicular stomatitis virus (VSV), an oncolytic virus, has demonstrated oncolytic (cancer-killing) ... 1 log TCID50 and the highly susceptible group having virus titer ,1 log TCID50. We hypothesized that virus replication in ...
Vaccinia virus protein C4 inhibits NF-κB activation and promotes virus virulence - CAMS Oxford Institute
A VACV lacking the C4L gene (vΔC4) showed no significant differences from wild-type virus in growth kinetics or spread in cell ... C4 represents the ninth VACV protein to inhibit NF-κB activation and remarkably, in every case examined, loss of each protein ... dependent promoter demonstrated that C4 inhibits NF-κB activation at, or downstream of, the inhibitor of kappa kinase (IKK) ... strain Western Reserve protein C4 has been characterized and its function and contribution to virus virulence assessed. ...
Immune activation alters cellular and humoral responses to yellow fever 17D vaccine
... and dengue virus infections. This study aimed to evaluate the contribution of the patient-specific immune microenvironment to ... Immune activation alters cellular and humoral responses to yellow fever 17D vaccine J Clin Invest. 2014 Jul;124(7):3147-58. doi ... Interestingly, activation of CD8+ T cells and B cells as well as proinflammatory monocytes at baseline negatively correlated ...
Prevention and Treatment of Tuberculosis Among Patients Infected
with Human Immunodeficiency Virus: Principles of Therapy and ...
Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear ... Mycobacterium tuberculosis enhances human immunodeficiency virus-1 replication by transcriptional activation at the long ... Human immunodeficiency virus type 1 (HIV-1) and M. tuberculosis are two intracellular pathogens that interact at the population ... A trial of three regimens to prevent tuberculosis in Ugandan adults infected with the human immunodeficiency virus. N Engl J ...
What Lies Beneath: Antibody Dependent Natural Killer Cell Activation by Antibodies to Internal Influenza Virus Proteins
Antibody Dependent Natural Killer Cell Activation by Antibodies to Internal Influenza Virus Proteins ... What Lies Beneath: Antibody Dependent Natural Killer Cell Activation by Antibodies to Internal Influenza Virus Proteins. ... We studied NP and M1-specific ADCC activity using biochemical, NK cell activation and killing assays with plasma from healthy ... Natural symptomatic and experimental influenza infections resulted in a rise in antibody dependent NK cell activation post- ...
Molluscum contagiosum and herpes simplex in maasai pastoralists; refeeding activation of virus infection following famine?<...
Molluscum contagiosum and herpes simplex in maasai pastoralists; refeeding activation of virus infection following famine? ... Molluscum contagiosum and herpes simplex in maasai pastoralists; refeeding activation of virus infection following famine?. In ... Molluscum contagiosum and herpes simplex in maasai pastoralists; refeeding activation of virus infection following famine? / ... Molluscum contagiosum and herpes simplex in maasai pastoralists; refeeding activation of virus infection following famine?. ...
Influenza B virus triggering macrophage activation syndrome in an infant<...
title = "Influenza B virus triggering macrophage activation syndrome in an infant",. abstract = "Macrophage activation syndrome ... Influenza B virus triggering macrophage activation syndrome in an infant. / Jayashree, K.; Rao, Suchetha; Kamath, Nutan. In: ... Jayashree, K., Rao, S., & Kamath, N. (2017). Influenza B virus triggering macrophage activation syndrome in an infant. Indian ... Influenza B virus triggering macrophage activation syndrome in an infant. Indian Journal of Critical Care Medicine. 2017 Nov 1; ...