*  FGFR1肽 (806-821) (ab45685)|Abcam中国
Receptor for basic fibroblast growth factor. Receptor for FGF23 in the presence of KL (By similarity). A shorter form of the ... Defects in FGFR1 are a cause of Pfeiffer syndrome (PS) [MIM:101600]; also known as acrocephalosyndactyly type V (ACS5). PS is ... Fibroblast growth factor receptor subfamily.. Contains 3 Ig-like C2-type (immunoglobulin-like) domains.. Contains 1 protein ... Some isoforms are detected in foreskin fibroblast cell lines, however isoform 17, isoform 18 and isoform 19 are not detected in ...
  http://www.abcam.cn/fgfr1-peptide-806-821-ab45685.html
*  EEF1A1 | Cancer Genetics Web
Receptor, Fibroblast Growth Factor, Type 3. *Chromosome 6. *HeLa Cells. *Breast Cancer ... Here, we show that XPG knockdown represses epidermal growth factor (EGF)-induced FOS transcription at the level of ... The expression levels of the translational factors eEF1A 1/2 correlate with cell growth but not apoptosis in hepatocellular ... The role of translation elongation factor eEF1A in intracellular alkalinization-induced tumor cell growth.. Lab Invest. 2009; ...
  http://www.cancerindex.org/geneweb/EEF1A1.htm
*  FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy.
Novel therapies targeting receptor tyrosine kinases or activated oncogenes may improve ... Receptor, Fibroblast Growth Factor, Type 3 / genetics*. Tumor Markers, Biological / genetics. Tumor Suppressor Protein p53 / ... EC 2.7.10.1/Receptor, Fibroblast Growth Factor, Type 3; EC 3.6.5.2/ras Proteins ... Novel therapies targeting receptor tyrosine kinases or activated oncogenes may improve outcome. Hence, it is necessary to ...
  http://www.biomedsearch.com/nih/Fgfr3-hras-kras-nras-pik3ca/21072204.html
*  Dovitinib - AdisInsight
... an oral multi-targeted receptor tyrosine kinase inhibitor, for the treatment of cancer. Dovitinib strongly ... Platelet-derived growth factor beta receptor antagonists; Proto oncogene protein c-kit inhibitors; Type 3 fibroblast growth ... factor receptor antagonists; Vascular endothelial growth factor receptor antagonists * Orphan Drug Status Orphan designation is ... Alternative Names: CHIR-258; Dovitinib lactate; GFKI-258; Growth factor kinase inhibitor 258; TKI 258 Latest Information Update ...
  http://adisinsight.springer.com/drugs/800019244?error=cookies_not_supported&code=f9baf102-28b3-4938-adb3-5af360056640
*  Indian hedgehog (protein) - Wikipedia
... hedgehog expression is preserved in the growth plate of human fetuses affected with fibroblast growth factor receptor type 3 ... Zhang D, Schwarz EM, Rosier RN, Zuscik MJ, Puzas JE, O'Keefe RJ (September 2003). "ALK2 functions as a BMP type I receptor and ... 2002). "A novel mutation in the IHH gene causes brachydactyly type A1: a 95-year-old mystery resolved". Hum. Genet. 111 (4-5): ... 2003). "Identification of a mutation in the Indian Hedgehog (IHH) gene causing brachydactyly type A1 and evidence for a third ...
  https://en.wikipedia.org/wiki/Indian_hedgehog_(protein)
*  FGFR2 peptide (ab76150) | Abcam
Fibroblast growth factor receptor subfamily.. Contains 3 Ig-like C2-type (immunoglobulin-like) domains.. Contains 1 protein ... type 2); craniosynostosis, early demise, sporadic (type 3).. Defects in FGFR2 are the cause of Beare-Stevenson cutis gyrata ... By product type. Proteins and Peptides. Proteomics tools. Agonists, activators, antagonists and inhibitors. Lysates. Multiplex ... By product type. Primary antibodies. Secondary antibodies. ELISA, Matched Antibody Pairs and Multiplex Immunoassays. Cell and ...
  http://www.abcam.com/fgfr2-peptide-ab76150.html
*  Recombinant human FGFR3 protein (ab60857) | Abcam
Fibroblast growth factor receptor subfamily.. Contains 3 Ig-like C2-type (immunoglobulin-like) domains.. Contains 1 protein ... By product type. Proteins and Peptides. Proteomics tools. Agonists, activators, antagonists and inhibitors. Lysates. Multiplex ... By product type. Primary antibodies. Secondary antibodies. ELISA, Matched Antibody Pairs and Multiplex Immunoassays. Cell and ... Other types of bladder cancer include squamous cell carcinoma (cancer that begins in thin, flat cells) and adenocarcinoma ( ...
  http://www.abcam.com/recombinant-human-fgfr3-protein-ab60857.html
*  Anti-FGFR3 antibody - C-terminal (ab180906) | Abcam
Fibroblast growth factor receptor subfamily.. Contains 3 Ig-like C2-type (immunoglobulin-like) domains.. Contains 1 protein ... By product type. Proteins and Peptides. Proteomics tools. Agonists, activators, antagonists and inhibitors. Lysates. Multiplex ... Fibroblast growth factor receptor 3 (achondroplasia thanatophoric dwarfism) antibody. *Fibroblast growth factor receptor 3 ... By product type. Primary antibodies. Secondary antibodies. ELISA, Matched Antibody Pairs and Multiplex Immunoassays. Cell and ...
  http://www.abcam.com/fgfr3-antibody-c-terminal-ab180906.html
*  List of MeSH codes (D12.776.543) - Wikipedia
... receptor, fibroblast growth factor, type 1 MeSH D12.776.543.750.060.092 -- receptor, fibroblast growth factor, type 2 MeSH ... receptor, fibroblast growth factor, type 1 MeSH D12.776.543.750.750.400.370.750 -- receptor, fibroblast growth factor, type 2 ... receptor, fibroblast growth factor, type 4 MeSH D12.776.543.750.750.400.370.968 -- receptor, fibroblast growth factor, type 5 ... receptors, tumor necrosis factor, type i MeSH D12.776.543.750.705.852.760.798 -- receptors, tumor necrosis factor, type ii MeSH ...
  https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D12.776.543)
*  benign cementoblastoma 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Chemical-registry-number] EC 2.7.10.1 / FGFR3 protein, human; EC 2.7.10.1 / Receptor, Fibroblast Growth Factor, Type 3 ... Publication-Type. And with publication types: Clinical Trial. Editorial. Letter. Meta-Analysis. Practice Guideline. Randomized ... include both record types include both record types but rank higher the records having abstract (the default BML behavior) + ... Hepatocyte Growth Factor; EC 3.1.3.1 / Alkaline Phosphatase ... Publication-type] Journal Article; Research Support, Non-U.S. ...
  http://www.bmlsearch.com/?kwr=benign+cementoblastoma+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
*  Anti-FGFR1 (phospho Y766) 抗体 (ab59180) | アブカム
Receptor for basic fibroblast growth factor. Receptor for FGF23 in the presence of KL (By similarity). A shorter form of the ... Defects in FGFR1 are a cause of Pfeiffer syndrome (PS) [MIM:101600]; also known as acrocephalosyndactyly type V (ACS5). PS is ... Fibroblast growth factor receptor subfamily.. Contains 3 Ig-like C2-type (immunoglobulin-like) domains.. Contains 1 protein ... ß1 integrin and Src-dependent phosphorylation of fibroblast growth factor receptor-1 at tyrosines 653/654 and 766.. J Biol Chem ...
  http://www.abcam.co.jp/fgfr1-phospho-y766-antibody-ab59180.html
*  Anti-FGFR2 抗体 [EPR5180] (ab109372) | アブカム
Fibroblast growth factor receptor subfamily.. Contains 3 Ig-like C2-type (immunoglobulin-like) domains.. Contains 1 protein ... type 2); craniosynostosis, early demise, sporadic (type 3).. Defects in FGFR2 are the cause of Beare-Stevenson cutis gyrata ... Lane 1: Wild-type HAP1 cell lysate (20 µg). Lane 2: FGFR2 knockout HAP1 cell lysate (20 µg). Lane 3: HeLa cell lysate (20 µg). ... Wild-type and FGFR2 knockout samples were subjected to SDS-PAGE. Ab109372 and ab8245 (loading control to GAPDH) were diluted at ...
  http://www.abcam.co.jp/fgfr2-antibody-epr5180-ab109372.html
*  FGFR3抗体(ab10651)| Abcam中国
Fibroblast growth factor receptor subfamily.. Contains 3 Ig-like C2-type (immunoglobulin-like) domains.. Contains 1 protein ... One receptor type may bind several of the FGFs with a similar affinity. Also, one FGF type may bind similarly to several ... Fibroblast growth factor receptor 3 (achondroplasia thanatophoric dwarfism) antibody. *Fibroblast growth factor receptor 3 ... Fibroblast growth factors (FGFs) are members of a large family of structurally related polypeptides (MW 17-38 kD) that are ...
  http://www.abcam.cn/fgfr3-antibody-ab10651.html
*  Recombinant human FGFR2 protein (ab80368) | アブカム
Fibroblast growth factor receptor subfamily.. Contains 3 Ig-like C2-type (immunoglobulin-like) domains.. Contains 1 protein ... type 2); craniosynostosis, early demise, sporadic (type 3).. Defects in FGFR2 are the cause of Beare-Stevenson cutis gyrata ... Defects in FGFR2 are the cause of Crouzon syndrome (CS) [MIM:123500]; also called craniofacial dysostosis type I (CFD1). CS is ... Defects in FGFR2 are a cause of Pfeiffer syndrome (PS) [MIM:101600]; also known as acrocephalosyndactyly type V (ACS5). PS is ...
  http://www.abcam.co.jp/recombinant-human-fgfr2-protein-ab80368.html
*  FGF21 - Wikipedia
FGF21 stimulates phosphorylation of fibroblast growth factor receptor substrate 2 and ERK1/2 in the liver. Acute FGF21 ... FGF21 stimulates glucose uptake in adipocytes but not in other cell types. This effect is additive to the activity of insulin. ... "Liver X receptor negatively regulates fibroblast growth factor 21 in the fatty liver induced by cholesterol-enriched diet". The ... Fibroblast growth factor 21 is a protein that in mammals is encoded by the FGF21 gene. The protein encoded by this gene is a ...
  https://en.wikipedia.org/wiki/FGF21
*  Diversity of Lung Stem and Progenitor Cell Types | SpringerLink
Dynamic regulation of platelet-derived growth factor receptor alpha expression in alveolar fi broblasts during ... Evans, M. J., Cabral, L. J., Stephens, R. J., & Freeman, G. (1975). Transformation of alveolar type 2 cells to type 1 cells ... El-Hashash A. (2018) Diversity of Lung Stem and Progenitor Cell Types. In: Lung Stem Cell Behavior. Springer, Cham. * DOI https ... Li, F., He, J., Wei, J., Cho, W. C., & Liu, X. (2015). Diversity of epithelial stem cell types in adult lung. Stem Cells ...
  https://link.springer.com/chapter/10.1007%2F978-3-319-95279-6_2
*  Amelioration of Type 2 Diabetes by Antibody-Mediated Activation of Fibroblast Growth Factor Receptor 1 | Science Translational...
Amelioration of Type 2 Diabetes by Antibody-Mediated Activation of Fibroblast Growth Factor Receptor 1 ... Amelioration of Type 2 Diabetes by Antibody-Mediated Activation of Fibroblast Growth Factor Receptor 1 ... Amelioration of Type 2 Diabetes by Antibody-Mediated Activation of Fibroblast Growth Factor Receptor 1 ... Amelioration of Type 2 Diabetes by Antibody-Mediated Activation of Fibroblast Growth Factor Receptor 1 ...
  http://stm.sciencemag.org/content/3/113/113ra126
*  Interleukin-1 receptor type 1 (IPR004076) | InterPro | EMBL-EBI
Patterns of structure and sequence in the Kunitz inhibitors interleukins-1 beta and 1 alpha and fibroblast growth factors.. J. ... Interleukin-1 receptor family (IPR015621) *Interleukin-1 receptor type I/II (IPR004074) *Interleukin-1 receptor type 1 ( ... these have been termed type I and type II receptors [PMID: 8702856]. The receptors both exist in transmembrane (TM) and soluble ... This entry represents Interleukin-1 receptor type 1 (IL1R1), the crystal structure of the soluble extracellular part of type-I ...
  http://www.ebi.ac.uk/interpro/entry/IPR004076
*  Type 2 Fibroblast Growth Factor Receptor - Fibroblast Growth Factor Receptor 2 Summary Report | CureHunter
... receptor 2 is found mainly in EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. ... One receptor isoform is found in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform of fibroblast ... Mutation of the gene for fibroblast growth factor receptor 2 can result in APERT SYNDROME. ... A fibroblast growth factor receptor that is found in two isoforms. ...
  http://www.curehunter.com/public/keywordSummaryD051497-Type-2-Fibroblast-Growth-Factor-Receptor-Fibroblast-Growth-Factor-Receptor-2.do
*  Global Fibroblast Growth Factor Receptor 3 Market Insights, Forecast to 2025 | Grand Research Store
... focuses on the consumption of Fibroblast Growth Factor Receptor 3 in these regions. This research report categ ... This report studies the global market size of Fibroblast Growth Factor Receptor 3 in key regions like North America, Europe, ... 1.4 Market by Type. 1.4.1 Global Fibroblast Growth Factor Receptor 3 Market Size Growth Rate by Type. 1.4.2 CPL-043. 1.4.3 ASP- ... 4 Breakdown Data by Type. 4.1 Global Fibroblast Growth Factor Receptor 3 Sales by Type. 4.2 Global Fibroblast Growth Factor ...
  https://www.grandresearchstore.com/life-sciences/global-fibroblast-growth-factor-receptor-2025-566
*  Nonamplified FGFR1 Is a Growth Driver in Malignant Pleural Mesothelioma | Molecular Cancer Research
Blockade of nonhormonal fibroblast growth factors by FP-1039 inhibits growth of multiple types of cancer. Sci Transl Med 2013;5 ... 17, 18), vascular-endothelial growth factor receptors (VEGFR; ref. 19), AXL (20, 21), and insulin-like growth factor receptor ( ... cell lines in which fibroblast growth factor receptor (FGFR) autocrine signaling functions as a nonmutated growth pathway. In a ... Fibroblast growth factor receptor 1 amplification is a common event in squamous cell carcinoma of the head and neck. Mod Pathol ...
  http://mcr.aacrjournals.org/content/12/10/1460
*  Thanatophoric dysplasia - Wikipedia
"The thanatophoric dysplasia type II mutation hampers complete maturation of fibroblast growth factor receptor 3 (FGFR3), which ... It can be associated with missense mutations in fibroblast growth factor receptor-3. It is inherited in an autosomal dominant ... Vajo, Zoltan; Francomano CA; Wilkin DJ (2000). "The molecular and genetic basis of fibroblast growth factor receptor 3 ... Norman AM, Rimmer S, Landy S, Donnai D (1992). "Thanatophoric dysplasia of the straight-bone type (type 2)". Clin. Dysmorphol. ...
  https://en.wikipedia.org/wiki/Thanatophoric_dysplasia
*  K-Ras and β-catenin mutations cooperate with Fgfr3 mutations in mice to promote tumorigenesis in the skin and lung, but not in...
Fibroblast growth factor receptor 3 (FGFR3) is a receptor tyrosine kinase that is known to mediate the effects of fibroblast ... 3C,D) when compared with wild-type bladders (Fig. 3A,B). By contrast, in papillomas from UroIICre+Fgfr3+/K644EK-RasG12D/+ mice ... 2001). Activated fibroblast growth factor receptor 3 is an oncogene that contributes to tumor progression in multiple myeloma. ... 1995). Fibroblast-growth-factor receptor mutations in human skeletal disorders. Trends Genet. 11, 308-313. ...
  http://dmm.biologists.org/content/4/4/548
*  Plus it
2011) Amelioration of type 2 diabetes by antibody-mediated activation of fibroblast growth factor receptor 1. Sci Transl Med 3: ... fibroblast growth factor. FGFR. fibroblast growth factor receptor. HRP. horseradish peroxidase. GLUT1. glucose transporter 1. ... 2008) Adipose fibroblast growth factor 21 is up-regulated by peroxisome proliferator-activated receptor gamma and altered ... 2012) Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor ...
  http://jpet.aspetjournals.org/content/346/2/270
*  The Multi-Level Action of Fatty Acids on Adiponectin Production by Fat Cells
Using mouse embryonic fibroblasts from C/EBPα-null mice, we have determined that the latter transcription factor may not solely ... Sortilin associates with transforming growth factor-beta family proteins to enhance lysosome-mediated degradation. The Journal ... we used differentiated Swiss fibroblasts stably transfected with wild type PPARγ or unphosphorylatable mutant of PPARγ where ... Sortilin/neurotensin receptor-3 binds and mediates degradation of lipoprotein lipase. J Biol Chem. 1999;274:8832-8836. [PubMed] ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC3226650/?lang=en-ca