RNA-binding protein - Wikipedia
DNA-binding protein RNA-binding protein database Ribonucleoprotein Wikimedia Commons has media related to RNA-binding proteins ... identification of RNA-binding proteins has extended the number of RNA-binding proteins significantly RNA-binding protein Sam68 ... intricacy of protein-RNA recognition of RRM as it entails RNA-RNA and protein-protein interactions in addition to protein-RNA ... cureted human RNA binding proteins database. RsiteDB: RNA binding site database SPOT-Seq-RNA: Template-based prediction of RNA ...
Modular RNA-Binding Protein System Kicks A**, Takes Names
First, they designed two Pumby proteins that would bind to adjacent RNA sequences. Each protein is also attached to half of a ... "We further demonstrate a new use of such RNA-binding proteins, measurement of RNA translation in living cells." ... These RNA-binding proteins could also be used to build molecular assembly lines that would bring together enzymes needed to ... Hoping to make the assembly of RNA-binding proteins less of a trial-and-error and more programmable task, the MIT researchers ...
![ELAVL3 ELAV like RNA binding protein 3 [Homo sapiens (human)] - Gene - NCBI](data:image/png;base64,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)
ELAVL3 ELAV like RNA binding protein 3 [Homo sapiens (human)] - Gene - NCBI
ELAVL3 ELAV like RNA binding protein 3 [Homo sapiens] ELAVL3 ELAV like RNA binding protein 3 [Homo sapiens]. Gene ID:1995 ... A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA ... ELAV like RNA binding protein 3provided by HGNC. Primary source. HGNC:HGNC:3314 See related. Ensembl:ENSG00000196361 MIM:603458 ... Analysis of the RNA recognition motifs of human neuronal ELAV-like proteins in binding to a cytokine mRNA. Sakai K, et al. ...
Specific RNA Binding Proteins News, Articles | Lab Manager
The Tristetraprolin Family of RNA-Binding Proteins in Cancer: Progress and Future Prospects
The tristetraprolin family of RNA-binding proteins (RBPs), which include Zinc Finger Protein 36 (ZFP36; commonly referred to as ... The Tristetraprolin Family of RNA-Binding Proteins in Cancer: Progress and Future Prospects Cancers (Basel). 2020 Jun 11;12(6): ... Mechanistically, these proteins function by binding to the AU-rich elements within the 3-untranslated regions of their target ... tristetraprolin (TTP)), Zinc Finger Protein 36 like 1 (ZFP36L1), and Zinc Finger Protein 36 like 2 (ZFP36L2), play key roles in ...
SCOP 1.71: Family a.232.1.1: RNA-binding protein She2p
RNA-binding protein She2p. Timeline for Family a.232.1.1: RNA-binding protein She2p: *Family a.232.1.1: RNA-binding protein ... Superfamily a.232.1: RNA-binding protein She2p [116942] (1 family) *. Family a.232.1.1: RNA-binding protein She2p [116943] (1 ... Family a.232.1.1: RNA-binding protein She2p appears in SCOP 1.73. *Family a.232.1.1: RNA-binding protein She2p appears in the ... Protein:. *. RNA-binding protein She2p [116944] (1 species). *. Species Bakers yeast (Saccharomyces cerevisiae) [TaxId:4932] [ ...
Integrating thermodynamic and sequence contexts improves protein-RNA binding prediction | PLOS Computational Biology
Identifying protein-RNA interactions and the binding preferences of RBPs are critical to unraveling the mechanism of post- ... we present a computational approach that integrates both structure and sequence contexts for protein-RNA binding prediction. We ... study suggests the great potential of our method as a practical tool for identifying novel protein-RNA interactions and binding ... empowered by a deep neural network that combines the sequence and structure information to achieve improved protein-RNA binding ...
Rbfox1 MGI Mouse Gene Detail - MGI:1926224 - RNA binding protein, fox-1 homolog (C. elegans) 1
protein coding gene. Chr16:5702566-7230344 (+). 129S1/SvImJ MGP_129S1SvImJ_G0022490. protein coding gene. Chr16:3429752-4069285 ... protein coding gene. Chr16:3423402-4031042 (+). C57BL/6NJ MGP_C57BL6NJ_G0022906. protein coding gene. Chr16:3512693-4137041 (+) ... protein coding gene. Chr16:3514609-4149610 (+). NZO/HlLtJ MGP_NZOHlLtJ_G0022918. protein coding gene. Chr16:3379863-4004963 (+) ... protein coding gene. Chr16:3390551-4005556 (+). SPRET/EiJ MGP_SPRETEiJ_G0021321. protein coding gene. Chr16:3455679-4082114 (+) ...
PRIME PubMed | Structural characterization of Escherichia coli ribosomal protein S8 and its binding site in 16S ribosomal RNA
Structural characterization of Escherichia coli ribosomal protein S8 and its binding site in 16S ribosomal RNA. Download Prime ... The RNA binding site of S8 ribosomal protein of Escherichia coli: Selex and hydroxyl radical probing studies. ... "Structural Characterization of Escherichia Coli Ribosomal Protein S8 and Its Binding Site in 16S Ribosomal RNA." Nucleic Acids ... Structural characterization of Escherichia coli ribosomal protein S8 and its binding site in 16S ribosomal RNA. Nucleic Acids ...
Axonal localization of the Fragile X family of RNA binding proteins is conserved across mammals | bioRxiv
The function and regulation of RNA granules are heavily dependent on the RNA binding proteins found within those granules. FXGs ... family of RNA binding proteins: FMRP (Fragile X mental retardation protein), FXR2P, and FXR1P. FMRP, which is mutated in the ... Axonal localization of the Fragile X family of RNA binding proteins is conserved across mammals. Katherine A. Shepard, Lulu I T ... Fragile X granules (FXGs) are axonal RNPs containing the Fragile X related family of RNA binding proteins along with ribosomes ...
A Candidate RNAi Screen Reveals Diverse RNA-Binding Protein Phenotypes in Drosophila Flight Muscle
RNA binding proteins (RBPs) regulate the diverse steps in RNA processing, including alternative splicing, which generates fiber ... A Candidate RNAi Screen Reveals Diverse RNA-Binding Protein Phenotypes in Drosophila Flight Muscle. In: Cells, Vol. 10, No. 10 ... The proper regulation of RNA processing is critical for muscle development and the fine-tuning of contractile ability among ... specific isoforms of structural proteins that confer contractile sarcomeres with distinct biomechanical properties. Alternative ...
High expression of insulin-like growth factor binding protein-2 messenger RNA in epithelial ovarian cancers produces elevated...
High expression of insulin-like growth factor binding protein-2 messenger RNA in epithelial ovarian cancers produces elevated ... High expression of insulin-like growth factor binding protein-2 messenger RNA in epithelial ovarian cancers produces elevated ... High expression of insulin-like growth factor binding protein-2 messenger RNA in epithelial ovarian cancers produces elevated ... Using microarray expression analysis, we recently reported that expression of the insulin-like growth factor binding protein-2 ...
RNA-binding proteins distinguish between similar sequence motifs to promote targeted deadenylation by Ccr4-Not | eLife
Biochemical reconstitution of deadenylation and analysis of binding kinetics reveals how RNA-binding proteins select their mRNA ... A) RNA-binding proteins (RBPs) promote targeted deadenylation by simultaneously binding to RNA via an RNA-binding domain (RBD) ... Identification of mRNA targets of RNA-binding proteins. Even when the consensus motif recognized by an RNA-binding protein is ... Ccr4-Not recruitment by RNA-binding proteins. RNA-binding proteins that interact with the mRNA decay machinery typically ...
Description: Y-Complex Proteins Show RNA-Dependent Binding Events at the Cell Membrane and Distinct Single-Molecule Dynamics ::...
Y-Complex Proteins Show RNA-Dependent Binding Events at the Cell Membrane and Distinct Single-Molecule Dynamics Bacteria are ... supporting their involvement in global RNA degradation. However, Y-complex proteins show distinguishable protein dynamics, and ... In Bacillus subtilis, RNase Y in turn interacts with the so-called "Y-complex" consisting of three proteins, which play ... A prerequisite for rapid adaptations is efficient RNA turnover, with endonuclease RNase Y playing a crucial role in mRNA ...
"MUTATIONS OF FUS CAUSE AGGREGATION OF RNA BINDING PROTEINS, DISRUPTION" by Marisa Elizabeth Kamelgarn
We identified a cohort of proteins involved in translation, splicing, and RNA export to be associated with the FUS inclusions. ... Further pathway and disease association analysis suggested that proteins associated with translation and RNA quality control ... Protein translation assays using both N2A and ALS patient fibroblasts demonstrated suppression of protein biosynthesis in ... RNA splicing, RNA transport, localized translation, and stress response. Their interaction with FUS varied greatly in their ...
Identification of nonspecific RNA-binding proteins leads to characterization of Lhp1 as a robust ATP-independent RNA chaperone
These RNA chaperone proteins are biologically critical, and they have long been hypothesized to possess nonspecific RNA binding ... we performed affinity purifications of budding yeast RNA-binding proteins, using an exogenous and non-orthologous RNA as bait: ... and analysis of multiple replicates revealed a sizable consistent population that was highly enriched in RNA-binding proteins. ... Proteins that co-purified with the RNA were identified by mass spectrometry, ...
Research Associate in Secreted Extra-Organismal RNA-Binding Proteins - University of Cambridge - Department of Biochemistry,...
Apply for the Research Associate in Secreted Extra-Organismal RNA-Binding Proteins Job, University of Cambridge - Department of ... Research Associate in Secreted Extra-Organismal RNA-Binding Proteins. Saved Save this Job Saved Save ... imaging and high-throughput sequencing to assess the impact of RNA binding on protein/RNA stability and function. They will ... We isolated two secreted milk proteins with robust yet unknown RNA-binding capacity, playing essential metabolic roles. Both ...
It takes three to tango: transcription factors bind DNA, protein, and RNA | Whitehead Institute
Now, researchers in Whitehead Institute Member Richard Youngs lab find that many transcription factors can also bind RNA, ... RNA binding region as such is because it is not a typical RNA binding domain. Typical RNA binding domains form stable ... RNA binding fine tunes gene expression. Next, the researchers tested to see if RNA binding affected the transcription factors ... However, Tat does not contain a structured RNA binding site; instead, it binds RNA from a region called an arginine-rich motif ...
RNA binding proteins involved in regulation of protein synthesis to initiate biogenesis of secondary tumor in hepatocellular...
... based on the function of RNA binding proteins (RBPs)-encoding genes in the physiological microenvironment (PM). Methods The ... The samples were analyzed using the technology of RNA-seq and bioinformatics. The differentially expressed RBPs-encoding genes ... and translation of proteins. Conclusion The genes encoding RBPs and the relevant genes are involved in the transformation from ... PM to PTM, then constructing the TM by regulating protein synthesis. This regulation included whole process of biological ...
Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins. - Wikidata
Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins.. scientific article published in ... Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins. (English) ... A Drosophila RNA polymerase II transcription factor binds to the regulatory site of an hsp 70 gene. ... A Drosophila RNA polymerase II transcription factor contains a promoter-region-specific DNA-binding activity. ...
Deep neural networks for inferring binding sites of RNA-binding proteins by using distributed representations of RNA primary...
... which combines primary RNA sequence and secondary structure information to effectively predict RBP binding sites. Specifically ... However, the determination of RBP binding sites on a large scale is a challenging task due to high cost of biochemical assays. ... The identification of RBP binding sites is a crucial step in understanding the biological mechanism of post-transcriptional ... Quite a number of studies have exploited machine learning methods to predict binding sites. Especially, deep learning is ...
The case for membrane-associated RNA-binding proteins in Saccharomyces cerevisiae
... is the site of protein synthesis for secretory and membrane proteins. I aimed to identify RNA-binding proteins (RBPs) in yeast ... The case for membrane-associated RNA-binding proteins in Saccharomyces cerevisiae. DSpace Repository. Login ... The case for membrane-associated RNA-binding proteins in Saccharomyces cerevisiae. Syed, Muhammad Ibrahim ... RNA seq analysis in combination with qPCR and microscopic data revealed that mRNAs coding for nuclear-related proteins can also ...
PTRE-seq reveals mechanism and interactions of RNA binding proteins and miRNAs | Cell Biology & Physiology | Washington...
Immunological detection of the messenger RNA cap-binding protein<...
Immunological detection of the messenger RNA cap-binding protein. / Hiremath, L. S.; Webb, N. R.; Rhoads, R. E. In: Journal of ... Hiremath, L. S. ; Webb, N. R. ; Rhoads, R. E. / Immunological detection of the messenger RNA cap-binding protein. In: Journal ... Hiremath, L. S., Webb, N. R., & Rhoads, R. E. (1985). Immunological detection of the messenger RNA cap-binding protein. Journal ... title = "Immunological detection of the messenger RNA cap-binding protein",. author = "Hiremath, {L. S.} and Webb, {N. R.} and ...
C6orf203 is an RNA-binding protein involved in mitochondrial protein synthesis :: MPG.PuRe
RNA, Ribosomal/genetics,br/,RNA-Binding Proteins/*genetics/physiology; Title: C6orf203 is an RNA-binding protein involved in ... Mitochondrial Proteins/*biosynthesis/genetics/physiology,br/,Mitochondrial Ribosomes/metabolism,br/,RNA, Messenger/genetics,br ... RNAs are associated with RNA-binding proteins (RBPs), forming complexes that control gene regulatory mechanisms, from RNA ... 2019). C6orf203 is an RNA-binding protein involved in mitochondrial protein synthesis. Nucleic Acids Res, 47(17), 9386-9399. ...
Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1.
Hel-N1, a human RNA-binding protein, shares significant homology with Drosophila protein ELAV, which is essential for fly ... Selection of a subset of mRNAs from combinatorial 3 untranslated region libraries using neuronal RNA-binding protein Hel-N1.. ... "Selection of a subset of mRNAs from combinatorial 3 untranslated region libraries using neuronal RNA-binding protein Hel-N1." ... "Selection of a subset of mRNAs from combinatorial 3 untranslated region libraries using neuronal RNA-binding protein Hel-N1." ...
RNA Binding Proteins in Cancer - Shrikant Anant
The broad goal of the project is to understand the mechanisms by which RNA binding protein RBM3 regulates gene expression at ... RNA Binding Proteins in Cancer. Anant, Shrikant / University of Kansas. $283,799. NIH 2012. R01 CA. RNA Binding Proteins in ... RNA Binding Proteins in Cancer. Anant, Shrikant / University of Kansas. $301,913. NIH 2010. R01 CA. RNA Binding Proteins in ... we will determine the mechanism by which RNA binding protein RBM3 regulates gene expression. Here, we will identify the RNA ...
The importance of resting phases in B cell development | ScienceDaily
"We found that the two proteins, RNA binding proteins ZFP36L1 and ZFP36L2, promote cell quiescence by blocking the RNA messages ... Role of RNA binding proteins discovered. Date:. April 21, 2016. Source:. Babraham Institute. Summary:. Everyone preparing for ... RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence. Science, 2016; 352 (6284): 453 DOI: 10.1126/science.aad5978 ... the contribution of sequence-specific RNA binding proteins was unknown. Our findings shed light on the intricate control and ...
Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans | Nature Reviews Genetics
... to a gene promoter to initiate RNA synthesis, emerging evidence points to the pausing of Pol II during early elongation as a ... whereas traditional models focused solely on the events that brought RNA polymerase II (Pol II) ... Emerging evidence points towards RNA polymerase II promoter-proximal pausing as a widespread regulatory mechanism in higher ... The nexus between RNA-binding proteins and their effectors *Shiyang He. *Eugene Valkov ...
RBPWorld - a comprehensive database of RNA Binding Proteins
RNA binding domain. Wyosine_form. Summary. Wybutosine (yW) is a hypermodified guanosine found in phenylalanine tRNA adjacent to ... enables metal ion binding. 1. IEA. Homo_sapiens(9606). Function. GO:0051539. enables 4 iron, 4 sulfur cluster binding. 1. IEA. ... Protein ID. Perc_pos. Perc_id. Species. Protein ID. Perc_pos. Perc_id. ... Protein ID. Perc_pos. Perc_id. Species. Protein ID. Perc_pos. Perc_id. ...