Rapid identification of virulent type I strains of the protozoan pathogen Toxoplasma gondii by PCR-restriction fragment length...
Protozoan Proteins / genetics* Actions. * Search in PubMed * Search in MeSH * Add to Search ... Rapid identification of virulent type I strains of the protozoan pathogen Toxoplasma gondii by PCR-restriction fragment length ... Rapid identification of virulent type I strains of the protozoan pathogen Toxoplasma gondii by PCR-restriction fragment length ...
Simulation of B cell affinity maturation explains enhanced antibody cross-reactivity induced by the polyvalent malaria vaccine...
A Comprehensive Analysis of Plasmodium Circumsporozoite Protein Binding to Hepatocytes
... is the dominant protein on the surface of Plasmodium sporozoites and plays a critical role in the invasion by sporozoites of ... Protein Binding * Protozoan Proteins / metabolism* * Signal Transduction * Sporozoites / metabolism* Substances * Protozoan ... Circumsporozoite protein (CSP) is the dominant protein on the surface of Plasmodium sporozoites and plays a critical role in ... A Comprehensive Analysis of Plasmodium Circumsporozoite Protein Binding to Hepatocytes PLoS One. 2016 Aug 25;11(8):e0161607. ...
EN (en)
The small GTP-binding protein RacG regulates uroid formation in the protozoan parasite Entamoeba histolytica. ... This protein belongs to the Rac subfamily of small GTPases implicated in interactions between the actin cytoskeleton and the ... Cloning of the EhracG gene and analysis of the protein activity either in murine fibroblasts or in E. histolytica revealed that ... When expressed in amoebae, an EhRacG-V12 mutant protein not only deregulated cell polarity, but also caused a defect in ...
Giardiasis - Wikipedia
Rupil, Lucía Lara; Serradell, Marianela Del Carmen; Luján, Hugo Daniel (January 2020). "Using Protozoan Surface Proteins for ... They are targeting: recombinant proteins, DNA vaccine, variant-specific surface proteins (VSP), cyst wall proteins (CWP), ... "Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins". Nature Communications. 10 ( ... substantial downregulation of the anti-apoptotic protein Bcl-2 and upregulation of the proapoptotic protein Bax. These ...
Primary Faculty | Microbial Pathogenesis
Protozoan Proteins. *Legionella pneumophila. *Coxiella burnetii. *Vesicular Transport Proteins. *. [email protected] ...
Shimi Meleppattu, Ph.D. | Harvard Catalyst Profiles | Harvard Catalyst
Dr. Robert D. Hinrichsen - Department of Biology - IUP
Protein phosphatases in the protozoan Paramecium. In: Advances in Protein Phosphatases. (ed. W. Merlevede). ... This research included the study of the calcium-binding protein calmodulin and its role in both the activation of Ca2+-dep. K+ ... We have also shown that this frequency also has a circadian component as well that is altered when the protein kinase glycogen ... Protein Phosphatase 2B (PP2B, Calcineurin) in Paramecium: Partial Characterization Reveals that Two Members of the Unusually ...
What's New for 2010 MeSH. NLM Technical Bulletin. 2009 Nov-Dec
"Protozoan." Thus the headings Protozoan Infections, Protozoan Genes, and Protozoan Proteins, etc. have not changed. ... Common usage of the word "protozoan" still exists in the literature, though it is diminishing; for now we are going to retain ... Most of the organism descriptors that were treed under Protozoa are now treed under Eukaryota, some under different taxonomic ... The 20th century classification of Protozoa emphasized modes of nutrition and locomotion; 21st century classification is based ...
Felix O. Yarovinsky, M.D. | UR Medicine
... a protozoan protein sensor, has an intracellular localization that is controlled by a chaperone protein, Unc93B1. More recently ... TLR11 activation of dendritic cells by a protozoan profilin-like protein.. Yarovinsky F, Zhang D, Andersen JF, Bannenberg GL, ... The innovative use of cell type-specific ablation of the TLR/IL-1R adaptor protein MyD88 using the Cre-lox system has allowed ... Redundant and pathogenic roles for IL-22 in mycobacterial, protozoan, and helminth infections.. Wilson MS, Feng CG, Barber DL ...
Publication Detail
Protozoan Proteins/immunology*; Sequence Analysis, RNA; Toxoplasma/chemistry*; Toxoplasmosis/parasitology ... Title: Transcriptional Profiling Suggests T Cells Cluster around Neurons Injected with Toxoplasma gondii Proteins. ... a protozoan parasite, has evolved to evade the immune system and establish a chronic infection in specific cells and organs, ... gondii-Cre system that allows permanent marking and tracking of neurons injected with parasite effector proteins in vivo Using ...
SCOPe 2.08: Domain d1s61b : 1s61 B
Protein Protozoan/bacterial hemoglobin [46460] (6 species). *. Species Mycobacterium tuberculosis, HbN [TaxId:1773] [63437] (8 ... PDB Compounds: (B:) Hemoglobin-like protein HbN. SCOPe Domain Sequences for d1s61b_:. Sequence; same for both SEQRES and ATOM ... Class a: All alpha proteins [46456] (290 folds). *. Fold a.1: Globin-like [46457] (2 superfamilies). core: 6 helices; folded ... Family a.1.1.1: Truncated hemoglobin [46459] (2 proteins). lack the first helix (A). ...
Historical shifts in Brazilian P. falciparum population structure and drug resistance alleles - PubMed
Flavopereirine-An Alkaloid Derived from Geissospermum vellosii-Presents Leishmanicidal Activity In Vitro - PubMed
Pf CDPK1 is critical for malaria parasite gametogenesis and mosquito infection - PubMed
... calcium-dependent protein kinase 1 (,i,Pf,/i,CDPK1) from asexual erythrocytic stage have not been successful, indicating an ... Protozoan Proteins / physiology* Actions. * Search in PubMed * Search in MeSH * Add to Search ... Efforts to knock out Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) from asexual erythrocytic stage have ... A) Analysis of CDPK1 protein expression in the CDPK1 KO parasites. A representative Western blot with late asexual stages of WT ...
Tudor staphylococcal nuclease: biochemistry and functions | Cell Death & Differentiation
Owing to its high protein-protein binding affinity coexistent with enzymatic activity, TSN can exert its biochemical function ... Conservation along significant evolutionary distance, from protozoa to plants and animals, suggests important physiological ... here we took an attempt to summarize and update the available information about this intriguing multifunctional protein. ... is an evolutionarily conserved protein with invariant domain composition, represented by tandem repeat of staphylococcal ...
Biomarkers Search
1. Actin-related protein 4: An unconventional negative regulator of mitochondrial calcium in protozoan parasite Leishmania. ... 8. Unconventional actins and actin-binding proteins in human protozoan parasites.. Gupta CM; Thiyagarajan S; Sahasrabuddhe AA. ... Mitochondrial protein import pathways are functionally conserved among eukaryotes despite compositional diversity of the import ... In vitro import of proteins into mitochondria of Trypanosoma brucei and Leishmania tarentolae.. Hauser R; Pypaert M; Häusler T ...
Protozoan Parasite Aquaporins
Aquaporin Genes in Selected Protozoan Parasites as Drug Targets. *Protein Motion Analysis of Structure of Plasmodium falciparum ... Aquaporin Genes in Selected Protozoan Parasites as Drug Targets. *Protein Motion Analysis of Structure of Plasmodium falciparum ... The AQP family of small integral membrane proteins that transport water and proteins are evolutionarily conserved, although ... which codes for the N-terminal cytosolic protein part. As shown by northern and western blots, the characterized protozoan AQPs ...
Medical Science Monitor | Editorial: Current Status of Two Adjuvanted Malaria Vaccines and the World Health Organization (WHO)...
... trials involving the two leading adjuvanted malaria vaccines directed to the Plasmodium falciparum circumsporozoite protein ( ... Protozoan Proteins, World Health Organization ... directed to the Plasmodium falciparum circumsporozoite protein ...
The Importance of Technology Transfer | Better World
"We had discovered that protozoan parasites contain the enzyme protein farnesyltransferase," he says. "This same enzyme plays an ... We were working on the hypothesis that protein farnesyltransferase inhibitors might work against parasites," Buckner says. ... for years with a group of chemists led by Michael Gelb to develop compounds to treat infectious diseases caused by protozoan ...
Pneumocystis jiroveci Pneumonia (PJP): Overview of Pneumocystis jiroveci Pneumonia, Microbiology of Pneumocystis jiroveci...
... a component of fungi protein synthesis not found in protozoa, further supported this notion. ... It was initially mistaken for a trypanosome and then later for a protozoan. In the 1980s, biochemical analysis of the nucleic ... composition of Pneumocystis rRNA and mitochondrial DNA identified the organism as a unicellular fungus rather than a protozoan ...
New perspectives on the use of tropical plants to improve ruminant nutrition | Proceedings of the Nutrition Society | Cambridge...
Rumen protozoa ingest and digest bacteria and fungi, degrading their cellular protein to NH3. Microbial protein turnover due to ... The potential for tree forage supplements to manipulate rumen protozoa to enhance protein to energy ratios in ruminants fed on ... Williams, AG & Coleman, GS (1997) The rumen protozoa. In The Rumen Microbial Ecosystem, pp. 73-139 [Hobson, PN & Stewart, CS, ... Austin, PJ, Suchar, LA, Robbins, CT & Hagerman, AE (1989) Tannin-binding proteins in saliva of deer and their absence in saliva ...
SMART: SANT domain annotation
Structure of the R2R3 DNA binding domain of MYB1 protein from protozoan parasite trichomonas vaginalis in complex with MRE-1/ ... Click on the protein counts, or double click on taxonomic names to display all proteins containing SANT domain in the selected ... Solution NMR structure of the R2R3 DNA binding domain of Myb1 protein from protozoan parasite Trichomonas vaginalis. ... STRUCTURE OF MYB TRANSFORMING PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE. 1idz. STRUCTURE OF MYB TRANSFORMING PROTEIN, NMR, 20 ...
Specificity of SARS-CoV-2 antibody-detection assays against S and N protein among pre-COVID-19 sera from patients with...
... of SARS-CoV-2 antibody-detection assays against S and N protein among pre-COVID-19 sera from patients with protozoan and ... including anti-SARS-CoV-2 N-protein IgM, anti-SARS-CoV-2 N-protein IgG, and anti-Receptor Binding Domain (RBD) blocking ... We tested three SARS-CoV-2 antibody-detection assays against either the S or the N protein, among a large collection of pre- ... We tested assays against either the S or the N protein, among a large collection of well characterised pre-COVID-19 sera from ...
Theileria annulata histone deacetylase 1 (TaHDAC1) initiates schizont to merozoite stage conversion | Scientific Reports
Induction of merogony by FR235222 leads to an increase in expression of merozoite-marker (rhoptry) proteins. RNA-seq of ... Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii. ... 6). As they included TA16660 that codes for a protein with significant similarity to P. falciparum rhoptry neck protein 5 ( ... This panel included: 13 genes coding for proteins orthologous to T. gondii proteins, whose chromatin of the corresponding genes ...
Poor CD4+ T Cell Immunogenicity Limits Humoral Immunity to P. falciparum Transmission-Blocking Candidate Pfs25 in Humans.
Protozoan Proteins. , Recombinant Proteins. , Species Specificity. , Vaccination. , Young Adult. Journal Title. Front Immunol. ... Antibodies, Protozoan. , B-Lymphocytes. , CD4-Positive T-Lymphocytes. , Cells, Cultured. , Disease Models, Animal. , Epitopes. ...
MEDIA RELEASE: Looking for natural solutions to boost feed-efficiency in animal husbandry - CGIAR
The research evaluated the potential of forest plants to improve protein efficiency through inhibiting rumen protozoa, known ... Nairobi, Kenya, 8 July 2020 - More than 60% of protein fed to ruminant animals is excreted in the form of waste. This low feed- ... The study is entitled Giant milkweed (Calotropis gigantea): A new plant resource to inhibit protozoa and decrease ...
The UDP-Glc:Glycoprotein Glucosyltransferase Is Essential for Schizosaccharomyces pombe Viability under Conditions of Extreme...
Glucosylation of glycoproteins by mammalian, plant, fungal and trypanosomatid protozoa microsomal proteins ... Accumulation of misfolded proteins in the ER leads to the so-called unfolded protein response, that is, to the induction of ... Glucosylation of glycoproteins by mammalian, plant, fungal and trypanosomatid protozoa microsomal proteins ... The unfolded protein response and underglycosylation of glycoproteins in S. pombe mutant cells. (A) Wild-type, alg6, gpt1/alg6 ...
Growth of the protozoan parasite Entamoeba histolytica in 5-azacytidine has limited effects on parasite gene expression | BMC...
In the protozoan parasite Entamoeba histolytica, a DNA methyltransferase has been identified and treatment with 5-azacytidine ( ... Jacobs T, Leippe M: Purification and molecular cloning of a major antibacterial protein of the protozoan parasite Entamoeba ... Protein concentration of the cell lysate was determined relative to this standard curve. The protein concentration (ng/cell) ... Protein concentration determination. Protein concentration was determined using the method of Bradford [68]. Briefly, ...