*  Protein phosphatase 2A promotes the transition to G0 during terminal differentiation in Drosophila | Development
Error bars indicate s.e.m. (C,D) S2R+ cells transfected with a CycE expression vector were treated with 50 nM okadaic acid (OA ... where we can use short-term treatments with the pan-PP2A inhibitor okadaic acid (OA) to discern immediate versus indirect ...
  http://dev.biologists.org/content/142/17/3033
*  Entry into mitosis without Cdc2 kinase activation | Journal of Cell Science
Okadaic acid-induced entry into mitosis is accompanied by partial activation of Cdc25C and may be prevented by tyrosine ... Using in-gel assays, we show that a 45-kDa protein kinase normally activated at mitosis is also activated by okadaic acid ... We now show that okadaic acid also induces two other landmark events of early mitosis, nuclear lamina depolymerization and ... Incubation of arrested cells with the protein phosphatase 1 and 2A inhibitor okadaic acid induces morphologically normal ...
  http://jcs.biologists.org/content/111/22/3401
*  Protein kinase-dependent effects of okadaic acid on hepatocytic autophagy and cytoskeletal integrity | Biochemical Journal
Protein kinase-dependent effects of okadaic acid on hepatocytic autophagy and cytoskeletal integrity. I Holen, P B Gordon, P O ... Okadaic acid was effectively antagonized by the general protein kinase inhibitors K-252a and KT-5926, the calmodulin antagonist ... The protein phosphatase inhibitor okadaic acid suppressed autophagy completely in isolated rat hepatocytes, as measured by the ... Protein kinase-dependent effects of okadaic acid on hepatocytic autophagy and cytoskeletal integrity ...
  http://www.biochemj.org/content/284/3/633
*  Protein phosphatase 2A is the main phosphatase involved in the regulation of protein kinase B in rat adipocytes.
Incubation of adipocytes with 1 microM okadaic acid inhibited PP2A by 75% and PP1 activity by only 17%, while 1 microM ... Incubation of adipocytes with 1 microM okadaic acid inhibited PP2A by 75% and PP1 activity by only 17%, while 1 microM ... Incubation of adipocytes with 1 microM okadaic acid inhibited PP2A by 75% and PP1 activity by only 17%, while 1 microM ... Okadaic Acid/pharmacology, Rats, Subcellular Fractions, Support, Non-U.S. Gov't, Proto-Oncogene Proteins/*metabolism. in ...
  https://lup.lub.lu.se/search/publication/106427
*  Okadaic acid - Wikipedia
However, the unique function of okadaic acid upon cells maintained biological interest in the molecule. Okadaic acid has been ... okadaic acid has shown promise in the world of medicine for numerous potential uses. During its initial discovery, okadaic acid ... was compared to and shown to be very chemically similar to okadaic acid several years later, and okadaic acid itself was ... several studies have been performed toward the synthesis of okadaic acid and its derivatives. 3 total syntheses of okadaic acid ...
  https://en.wikipedia.org/wiki/Okadaic_acid
*  OKADAIC ACID for protein prep - Protein and Proteomics
OKADAIC ACID for protein prep - (Apr/08/2010 ). Has anyone used okadaic acid as a phosphatase inhibitor when prepping protein ... Has anyone used okadaic acid as a phosphatase inhibitor when prepping protein from cell or tissue homogenates (for use in ... 3. How worried should I be about working with okadaic acid? It has a rather daunting MSDS....Any specific recommendations on ... 3. How worried should I be about working with okadaic acid? It has a rather daunting MSDS....Any specific recommendations on ...
  http://www.protocol-online.org/biology-forums-2/posts/14141.html
*  Marine Drugs | Free Full-Text | Okadaic Acid: A Tool to Study the Hippo Pathway
However other components of the Hippo pathway could also be targets of okadaic acid. In this review we first briefly summarize ... We explain how MST kinases are regulated by PP2A and how okadaic acid activates MST2. Thereafter we discuss which components of ... Okadaic acid has been frequently used to enhance the phosphorylation of MST1 and MST2 and to trigger the activation of the ... are activated in NIH3T3 cells exposed to okadaic acid. The Hippo pathway is a newly emerging signaling that functions as a ...
  http://mdpi.com/1660-3397/11/3/896/xml
*  Marine Drugs | Free Full-Text | Self-Association of Okadaic Acid: Structural and Pharmacological Significance | HTML
Okadaic acid (OA) has been an invaluable pharmacological tool in the study of cellular signaling. The great affinity of this ... 2. Dimerization of Okadaic Acid Overview. 2.1. Complexation of Okadaic Acid. Norte et al. first reported in 1991 that the toxin ... Figure 2. Structure proposed for the okadaic acid-potassium complex [21]. Each okadaic acid monomer is shown in a different ... Figure 2. Structure proposed for the okadaic acid-potassium complex [21]. Each okadaic acid monomer is shown in a different ...
  http://www.mdpi.com/1660-3397/11/6/1866/htm
*  Mimicking mitotic Golgi disassembly using okadaic acid | Journal of Cell Science
Mimicking mitotic Golgi disassembly using okadaic acid Message Subject (Your Name) has sent you a message from Journal of Cell ...
  http://jcs.biologists.org/content/103/4/875
*  Toxins | Free Full-Text | Single Laboratory Validation of A Ready-to-Use Phosphatase Inhibition Assay for Detection of Okadaic...
A phosphatase inhibition assay for detection of okadaic acid (OA) toxins in shellfish, OkaTest, was single laboratory validated ... Single Laboratory Validation of A Ready-to-Use Phosphatase Inhibition Assay for Detection of Okadaic Acid Toxins. Henry G. F. ... "Single Laboratory Validation of A Ready-to-Use Phosphatase Inhibition Assay for Detection of Okadaic Acid Toxins." Toxins 4, no ... A phosphatase inhibition assay for detection of okadaic acid (OA) toxins in shellfish, OkaTest, was single laboratory validated ...
  http://www.mdpi.com/2072-6651/4/5/339/xml
*  Toxins | Free Full-Text | PP2A Inhibition Assay Using Recombinant Enzyme for Rapid Detection of Okadaic Acid and Its Analogs in...
Okadaic acid and its analogs (OAs) responsible for diarrhetic shellfish poisoning (DSP) strongly inhibit protein phosphatase 2A ... Okadaic acid and its analogs (OAs) responsible for diarrhetic shellfish poisoning (DSP) strongly inhibit protein phosphatase 2A ... PP2A Inhibition Assay Using Recombinant Enzyme for Rapid Detection of Okadaic Acid and Its Analogs in Shellfish. Tsuyoshi ... "PP2A Inhibition Assay Using Recombinant Enzyme for Rapid Detection of Okadaic Acid and Its Analogs in Shellfish." Toxins 2, no ...
  http://www.mdpi.com/2072-6651/2/1/195
*  Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship | Biochemical...
The effect of structural modifications of okadaic acid (OA), a polyether C38 fatty acid, was studied on its inhibitory activity ... Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship. A Takai, M ... Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship ... Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship ...
  http://www.biochemj.org/content/284/2/539
*  Okadaic acid sodium salt - Alfa Chemistry
Okadaic acid sodium salt/ACM209266808 can be provided in Alfa Chemistry. We are dedicated to provide our customers the best ...
  http://www.alfa-chemistry.com/cas_209266-80-8.htm
*  Gentaur Molecular :LCLabs \ Okadaic Acid, Ammonium Salt \ O-6410
Okadaic Acid, Ammonium Salt \ O-6410 for more molecular products just contact us ... amino acid conjugation of benzoic acid. WP1307: Fatty Acid Beta Oxidation. WP1311: Folic Acid Network. WP133: Fatty Acid Omega ... amino acid conjugation of benzoic acid. WP1020: Fatty Acid Biosynthesis. WP105: Fatty Acid Beta Oxidation 2. WP1061: Fatty Acid ... amino acid conjugation of benzoic acid. WP1139: Fatty Acid Biosynthesis. WP1177: Fatty Acid Beta Oxidation. WP1192: Folic Acid ...
  http://www.antibody-antibodies.com/product_det.php?id=1445483&supplier=search&name=Okadaic%20Acid,%20Ammonium%20Salt
*  Phosphatase ABI1 and okadaic acid-sensitive phosphoprotein phosphatases inhibit salt stress-activated SnRK2.4 kinase
... Mostrar ... Phosphatase ABI1 and okadaic acid-sensitive phosphoprotein phosphatases inhibit salt stress-activated SnRK2.4 kinase. RiuNet: ... Phosphatase ABI1 and okadaic acid-sensitive phosphoprotein phosphatases inhibit salt stress-activated SnRK2.4 kinase ... Moreover, we show that the activity of SnRK2s from group 1 is additionally regulated by okadaic acid-sensitive phosphatase(s) ...
  https://riunet.upv.es/handle/10251/80769
*  Okadaic acid . ammonium salt (high purity), Enzo Life Sciences | VWR
Salt form of okadaic acid (Prod. No. ALX-350-003), with slightly greater stability than the free acid after it is put into ... Okadaic acid . ammonium salt (high purity), Enzo Life Sciences. Supplier: Enzo Life Sciences. ...
  https://us.vwr.com/store/product/10916556/okadaic-acid-ammonium-salt-high-purity-enzo-life-sciences
*  Plus it
Okadaic acid treatments.. Cells were grown and treated with PMA as described above. Undifferentiated monocytes as well as PMA- ... D: choline uptake for THP-1 monocytes and PMA-derived macrophages with and without okadaic acid (10 μM) treatments. Data are ... 4D that PMA-derived macrophages experience a further decrease in choline uptake when treated with okadaic acid compared with ... In addition, to further investigate this phosphorylation of CTL1, we used the protein phosphatase inhibitor okadaic acid (10). ...
  http://ajpcell.physiology.org/content/290/4/C1230
*  Toxins | Cellular Process | Toxins mechanism | Chemical toxins- AG Scientific
Okadaic acid, Free Form, Prorocentrum concavum O-1024. Options. 50 ug $87.16. 100 ug $153.62. 1 mg $1,078.60. ...
  https://www.agscientific.com/cell-biology/toxins.html
*  Microarrays | Free Full-Text | Testing a Microarray to Detect and Monitor Toxic Microalgae in Arcachon Bay in France | HTML
The target toxins are domoic acid (DA) for amnesic shellfish poisoning (ASP), okadaic acid (OA) and dinophysistoxins (DTXs) for ... Okadaic acid was detected by ELISA in all samples except for the first (sample 1A), and the Multi SPR gave no signal at all. We ... Domoic acid (DA) was detected with ELISA [23] (Table 5) in both October samples (4A and 6A) but not in sample 3A (22.08.2011) ... Acid. Res. 2004, 32, 1363-1371. [Google Scholar]. *Metfies, K.; Borsutzki, P.; Gescher, C.; Medlin, L.K.; Frickenhaus, S. ...
  http://www.mdpi.com/2076-3905/2/1/1/htm
*  A novel tetratricopeptide repeat (TPR) containing PP5 serine/threonine protein phosphatase in the malaria parasite, Plasmodium...
When using potential activators (e.g., fatty acids) or inhibitors (e.g., okadaic acid), they were added to the enzyme mixture ... Okadaic acid sensitivity of PfPP5. The differential sensitivity of the members of the PPP family to biological toxins has been ... The marine toxin okadaic acid (OA), in particular, inhibits the PP2A class of phosphatases at sub-nanomolar concentrations ( ... Okadaic Acid Catalytic Core Tetratricopeptide Repeat Nickel Chelation Affinity Chromatography Asexual Erythrocytic Stage ...
  https://rd.springer.com/article/10.1186/1471-2180-1-31
*  Toxins - Covalab Biotechnology
Okadaic acid antibody (7E1) [Alkaline... Product code : mab0028-AlP Raised in : Mouse. Clonality : Monoclonal antibody ...
  https://www.covalab.com/research-area/toxins.html
*  Plus it
Effect of okadaic acid on phosphorylation state of synapsin I at P-sites 1, 3, 4/5, and 6 in synaptosomes.A, Okadaic acid (OA; ... Louis, MO), or okadaic acid (Sigma), as noted in the legend to each figure, and each tube was placed at 37°C to start the ... Okadaic acid (0.5 μm) was added before the transition of synaptosomes to 37°C, and the incubation was performed for 10 min. ... A prominent increase in the state of phosphorylation of P-sites 1 and 3 was observed with okadaic acid treatment (Fig.4 A, P- ...
  http://www.jneurosci.org/content/21/20/7944
*  PPP2CB Gene - GeneCards | PP2AB Protein | PP2AB Antibody
Okadaic acid. Protein phosphatase 1 and 2A inhibitor. 78111-17-8. Tautomycetin. Selective PP1 inhibitor. 119757-73-2. ... 309 amino acids. Molecular mass:. 35575 Da. Cofactor:. Name=Mn(2+); Xref=ChEBI:CHEBI:29035;. Quaternary structure:. *Found in a ... of enzymes that catalyze the removal of phosphate groups from serine and/or threonine residues by hydrolysis of phosphoric acid ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=PPP2CB