*  Protein phosphatase 2A promotes the transition to G0 during terminal differentiation in Drosophila | Development
Error bars indicate s.e.m. (C,D) S2R+ cells transfected with a CycE expression vector were treated with 50 nM okadaic acid (OA ... where we can use short-term treatments with the pan-PP2A inhibitor okadaic acid (OA) to discern immediate versus indirect ...
  http://dev.biologists.org/content/142/17/3033
*  Entry into mitosis without Cdc2 kinase activation | Journal of Cell Science
Okadaic acid-induced entry into mitosis is accompanied by partial activation of Cdc25C and may be prevented by tyrosine ... Using in-gel assays, we show that a 45-kDa protein kinase normally activated at mitosis is also activated by okadaic acid ... We now show that okadaic acid also induces two other landmark events of early mitosis, nuclear lamina depolymerization and ... Incubation of arrested cells with the protein phosphatase 1 and 2A inhibitor okadaic acid induces morphologically normal ...
  http://jcs.biologists.org/content/111/22/3401
*  Plus it
... and okadaic acid (100 nM) caused tau mobility shifts similar to those seen after 10 microM okadaic acid treatment; similar ... Okadaic acid (1-20 microM) induced variant forms of tau at 60-68 kDa, which were recognized by the monoclonal antibodies Alz-50 ... A proposed tau-directed kinase, 42-kDa mitogen-activated protein kinase (p42mapk), was activated by okadaic acid (, 100 nM) but ... Treatment of human slices with 10 microM okadaic acid decreased both protein phosphatase 2A and calcineurin activity; FK-520 ...
  http://molpharm.aspetjournals.org/content/47/4/745
*  Protein kinase-dependent effects of okadaic acid on hepatocytic autophagy and cytoskeletal integrity | Biochemical Journal
Protein kinase-dependent effects of okadaic acid on hepatocytic autophagy and cytoskeletal integrity. I Holen, P B Gordon, P O ... Okadaic acid was effectively antagonized by the general protein kinase inhibitors K-252a and KT-5926, the calmodulin antagonist ... The protein phosphatase inhibitor okadaic acid suppressed autophagy completely in isolated rat hepatocytes, as measured by the ... Protein kinase-dependent effects of okadaic acid on hepatocytic autophagy and cytoskeletal integrity ...
  http://www.biochemj.org/content/284/3/633
*  Protein phosphatase 2A is the main phosphatase involved in the regulation of protein kinase B in rat adipocytes.
Incubation of adipocytes with 1 microM okadaic acid inhibited PP2A by 75% and PP1 activity by only 17%, while 1 microM ... Incubation of adipocytes with 1 microM okadaic acid inhibited PP2A by 75% and PP1 activity by only 17%, while 1 microM ... Incubation of adipocytes with 1 microM okadaic acid inhibited PP2A by 75% and PP1 activity by only 17%, while 1 microM ... Okadaic Acid/pharmacology, Rats, Subcellular Fractions, Support, Non-U.S. Gov't, Proto-Oncogene Proteins/*metabolism. in ...
  https://lup.lub.lu.se/search/publication/106427
*  OKADAIC ACID for protein prep - Protein and Proteomics
OKADAIC ACID for protein prep - (Apr/08/2010 ). Has anyone used okadaic acid as a phosphatase inhibitor when prepping protein ... Has anyone used okadaic acid as a phosphatase inhibitor when prepping protein from cell or tissue homogenates (for use in ... 3. How worried should I be about working with okadaic acid? It has a rather daunting MSDS....Any specific recommendations on ... 3. How worried should I be about working with okadaic acid? It has a rather daunting MSDS....Any specific recommendations on ...
  http://www.protocol-online.org/biology-forums-2/posts/14141.html
*  Marine Drugs | Free Full-Text | Okadaic Acid: A Tool to Study the Hippo Pathway
However other components of the Hippo pathway could also be targets of okadaic acid. In this review we first briefly summarize ... We explain how MST kinases are regulated by PP2A and how okadaic acid activates MST2. Thereafter we discuss which components of ... Okadaic acid has been frequently used to enhance the phosphorylation of MST1 and MST2 and to trigger the activation of the ... are activated in NIH3T3 cells exposed to okadaic acid. The Hippo pathway is a newly emerging signaling that functions as a ...
  http://mdpi.com/1660-3397/11/3/896/xml
*  Marine Drugs | Free Full-Text | Self-Association of Okadaic Acid: Structural and Pharmacological Significance | HTML
Okadaic acid (OA) has been an invaluable pharmacological tool in the study of cellular signaling. The great affinity of this ... 2. Dimerization of Okadaic Acid Overview. 2.1. Complexation of Okadaic Acid. Norte et al. first reported in 1991 that the toxin ... Figure 2. Structure proposed for the okadaic acid-potassium complex [21]. Each okadaic acid monomer is shown in a different ... Figure 2. Structure proposed for the okadaic acid-potassium complex [21]. Each okadaic acid monomer is shown in a different ...
  http://www.mdpi.com/1660-3397/11/6/1866/htm
*  Okadaic acid - Wikipedia
However, the unique function of okadaic acid upon cells maintained biological interest in the molecule. Okadaic acid has been ... okadaic acid has shown promise in the world of medicine for numerous potential uses. During its initial discovery, okadaic acid ... was compared to and shown to be very chemically similar to okadaic acid several years later, and okadaic acid itself was ... several studies have been performed toward the synthesis of okadaic acid and its derivatives. 3 total syntheses of okadaic acid ...
  https://en.wikipedia.org/wiki/Okadaic_acid
*  Mimicking mitotic Golgi disassembly using okadaic acid | Journal of Cell Science
Mimicking mitotic Golgi disassembly using okadaic acid Message Subject (Your Name) has sent you a message from Journal of Cell ...
  http://jcs.biologists.org/content/103/4/875
*  Toxins | Free Full-Text | Single Laboratory Validation of A Ready-to-Use Phosphatase Inhibition Assay for Detection of Okadaic...
A phosphatase inhibition assay for detection of okadaic acid (OA) toxins in shellfish, OkaTest, was single laboratory validated ... Single Laboratory Validation of A Ready-to-Use Phosphatase Inhibition Assay for Detection of Okadaic Acid Toxins. Henry G. F. ... "Single Laboratory Validation of A Ready-to-Use Phosphatase Inhibition Assay for Detection of Okadaic Acid Toxins." Toxins 4, no ... A phosphatase inhibition assay for detection of okadaic acid (OA) toxins in shellfish, OkaTest, was single laboratory validated ...
  http://www.mdpi.com/2072-6651/4/5/339/xml
*  Okadaic Acid, a Bioactive Fatty Acid from Halichondria okadai, Stimulates Lipolysis in Rat Adipocytes: The Pivotal Role of...
Okadaic Acid, a Bioactive Fatty Acid from Halichondria okadai, Stimulates Lipolysis in Rat Adipocytes: The Pivotal Role of ... P. Cohen, C. F. B. Holmes, and Y. Tsukitani, "Okadaic acid: a new probe for the study of cellular regulation," Trends in ... R. Nuydens, M. De Jong, G. Van Den Kieboom et al., "Okadaic acid-induced apoptosis in neuronal cells: evidence for an abortive ... T. A. J. Haystead, A. T. R. Sim, D. Carling et al., "Effects of the tumour promoter okadaic acid on intracellular protein ...
  https://www.hindawi.com/journals/ecam/2013/545739/ref/
*  Toxins | Free Full-Text | PP2A Inhibition Assay Using Recombinant Enzyme for Rapid Detection of Okadaic Acid and Its Analogs in...
Okadaic acid and its analogs (OAs) responsible for diarrhetic shellfish poisoning (DSP) strongly inhibit protein phosphatase 2A ... Okadaic acid and its analogs (OAs) responsible for diarrhetic shellfish poisoning (DSP) strongly inhibit protein phosphatase 2A ... PP2A Inhibition Assay Using Recombinant Enzyme for Rapid Detection of Okadaic Acid and Its Analogs in Shellfish. Tsuyoshi ... "PP2A Inhibition Assay Using Recombinant Enzyme for Rapid Detection of Okadaic Acid and Its Analogs in Shellfish." Toxins 2, no ...
  http://www.mdpi.com/2072-6651/2/1/195
*  Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship | Biochemical...
The effect of structural modifications of okadaic acid (OA), a polyether C38 fatty acid, was studied on its inhibitory activity ... Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship. A Takai, M ... Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship ... Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship ...
  http://www.biochemj.org/content/284/2/539
*  Okadaic Acid, Potassium Salt - CAS 155751-72-7 - Calbiochem CAS 155751-72-7 | 459618
... is a water-soluble analog of Okadaic Acid (Cat. No. 495604). A potent inhibitor of protein phosphatase 1 (IC50 = 10-15 nM) and ... More,, Okadaic Acid, Potassium Salt, CAS 155751-72-7, is a water-soluble analog of Okadaic Acid (Cat. No. 495604). A potent ... Okadaic Acid, Potassium Salt, CAS 155751-72-7, is a water-soluble analog of Okadaic Acid (Cat. No. 495604). A potent inhibitor ... Okadaic Acid, Potassium Salt, CAS 155751-72-7, is a water-soluble analog of Okadaic Acid (Cat. No. 495604). A potent inhibitor ...
  http://www.emdmillipore.com/PR/en/product/Okadaic-Acid-Potassium-Salt-CAS-155751-72-7-Calbiochem,EMD_BIO-459618
*  Okadaic Acid, Ammonium Salt - CAS 155716-06-6 - Calbiochem CAS 155716-06-6 | 459616
Water-soluble analog of Okadaic Acid. Inhibits protein phosphatases 1 and 2A. Find MSDS or SDS, a COA, data sheets and more ... Okadaic Acid, Ammonium Salt - CAS 155716-06-6 - Calbiochem. 459616 , Okadaic Acid, Ammonium Salt - CAS 155716-06-6 - Calbiochem ... Water-soluble analog of Okadaic Acid. Inhibits protein phosphatases 1 and 2A.. More,, Water-soluble analog of Okadaic Acid. ... Okadaic Acid, Prorocentrum sp. - CAS 78111-17-8 - Calbiochem. Show Pricing & Availability ...
  http://www.emdmillipore.com/US/en/product/Okadaic-Acid-Ammonium-Salt-CAS-155716-06-6-Calbiochem,EMD_BIO-459616
*  Okadaic acid sodium salt - Alfa Chemistry
Okadaic acid sodium salt/ACM209266808 can be provided in Alfa Chemistry. We are dedicated to provide our customers the best ...
  http://www.alfa-chemistry.com/cas_209266-80-8.htm
*  Gentaur Molecular :LCLabs \ Okadaic Acid, Ammonium Salt \ O-6410
Okadaic Acid, Ammonium Salt \ O-6410 for more molecular products just contact us ... amino acid conjugation of benzoic acid. WP1307: Fatty Acid Beta Oxidation. WP1311: Folic Acid Network. WP133: Fatty Acid Omega ... amino acid conjugation of benzoic acid. WP1020: Fatty Acid Biosynthesis. WP105: Fatty Acid Beta Oxidation 2. WP1061: Fatty Acid ... amino acid conjugation of benzoic acid. WP1139: Fatty Acid Biosynthesis. WP1177: Fatty Acid Beta Oxidation. WP1192: Folic Acid ...
  http://www.antibody-antibodies.com/product_det.php?id=1445483&supplier=search&name=Okadaic%20Acid,%20Ammonium%20Salt
*  Phosphatase ABI1 and okadaic acid-sensitive phosphoprotein phosphatases inhibit salt stress-activated SnRK2.4 kinase
... Mostrar ... Phosphatase ABI1 and okadaic acid-sensitive phosphoprotein phosphatases inhibit salt stress-activated SnRK2.4 kinase. RiuNet: ... Phosphatase ABI1 and okadaic acid-sensitive phosphoprotein phosphatases inhibit salt stress-activated SnRK2.4 kinase ... Moreover, we show that the activity of SnRK2s from group 1 is additionally regulated by okadaic acid-sensitive phosphatase(s) ...
  https://riunet.upv.es/handle/10251/80769
*  Okadaic acid . ammonium salt (high purity), Enzo Life Sciences | VWR
Salt form of okadaic acid (Prod. No. ALX-350-003), with slightly greater stability than the free acid after it is put into ... Okadaic acid . ammonium salt (high purity), Enzo Life Sciences. Supplier: Enzo Life Sciences. ...
  https://us.vwr.com/store/product/10916556/okadaic-acid-ammonium-salt-high-purity-enzo-life-sciences
*  Manganese in the structure of Structure of the Protein Phosphatase 2A Core Enzyme Bound to Okadaic Acid (pdb 2ie4)
Structure of the Protein Phosphatase 2A Core Enzyme Bound to Okadaic Acid ... Manganese in the structure of Structure of the Protein Phosphatase 2A Core Enzyme Bound to Okadaic Acid (pdb 2ie4). ... binding sites of Manganese atom in the structure of Structure of the Protein Phosphatase 2A Core Enzyme Bound to Okadaic Acid ( ...
  http://manganese.atomistry.com/pdb2ie4.html
*  Plus it
Okadaic acid treatments.. Cells were grown and treated with PMA as described above. Undifferentiated monocytes as well as PMA- ... D: choline uptake for THP-1 monocytes and PMA-derived macrophages with and without okadaic acid (10 μM) treatments. Data are ... 4D that PMA-derived macrophages experience a further decrease in choline uptake when treated with okadaic acid compared with ... In addition, to further investigate this phosphorylation of CTL1, we used the protein phosphatase inhibitor okadaic acid (10). ...
  http://ajpcell.physiology.org/content/290/4/C1230
*  Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein...
Okadaic acid inhibits many protein phosphatases, including protein phosphatase 1 (PP1) and PP2A, that can reverse PKA-catalyzed ... Migration of each was clearly retarded after incubation of cells for 3 h with 50 nM okadaic acid (OA), and the effect increased ... Incubation of HepG2 cells with okadaic acid caused concentration-dependent accumulation of presumably phosphorylated BIG1 and ... okadaic acid, cyclosporin A, and recombinant human PP1γ C subunit from EMD Biosciences (San Diego, CA); H-89 and orthovanadate ...
  http://www.pnas.org/content/104/9/3201