Creatine as a neuroprotective agent in manganese-induced neurotoxicity. UNCG Author/Contributor (non-UNCG co-authors, if there ... Creatine as a neuroprotective agent in manganese-induced neurotoxicity. PDF (Portable Document Format). 1089 KB. Created on 8/1 ... Creatine, Manganese, Neuroprotection, Neuroprotective, Neurotoxicity, Parkinson. Subjects. Creatine $x Therapeutic use $x ...

The results of this study suggest tropisetron warrants further investigation as a therapeutic agent against neurodegenerative ... Tropisetron as a Neuroprotective Agent Against Glutamate-Induced Excitotoxicity: Potential Mechanisms of Neuroprotection. ... Swartz, Michael M., "Tropisetron as a Neuroprotective Agent Against Glutamate-Induced Excitotoxicity: Potential Mechanisms of ... The results of this study suggest tropisetron warrants further investigation as a therapeutic agent against neurodegenerative ...

Progesterone as a neuroprotective agent in neonatal hypoxic-ischaemic encephalopathy-a systematic review. Developmental ... Progesterone as a neuroprotective agent in neonatal hypoxic-ischaemic encephalopathy-a systematic review ... Progesterone as a neuroprotective agent in neonatal hypoxic-ischaemic encephalopathy-a systematic review. ... Here, our objective was to evaluate the evidence base for PROG as a potential therapeutic agent in HIE. The PICO framework was ...

Neuroprotective Agents / pharmacology* * Neuroprotective Agents / therapeutic use * Pyrrolidinones / therapeutic use * ... Neuroprotective and cerebrovascular effects of GABA mimetics] Eksp Klin Farmakol. 2003 Mar-Apr;66(2):53-6. ...

Agents Med. Chem. 2012, 12, 82-94. [Google Scholar] [CrossRef] [PubMed]. *Kovacheva, V.P.; Mellott, T.J.; Davison, J.M.; Wagner ... Neuroprotective Actions of Perinatal Choline in Animal Models of Disease. 2.3.1. Epilepsy. Status epilepticus, a period of ... Moreover, choline is neuroprotective in a variety of experimental models of neuronal damage. Choline intake in adulthood may ... Blusztajn, J.K.; Mellott, T.J. Neuroprotective actions of perinatal choline nutrition. Clin. Chem. Lab. Med. 2013, 51, 591-599 ...

Neuroprotective Agents / chemistry * Neuroprotective Agents / pharmacology* * Rats Substances * Basic Helix-Loop-Helix ... Discovery of a proneurogenic, neuroprotective chemical Cell. 2010 Jul 9;142(1):39-51. doi: 10.1016/j.cell.2010.06.018. ...

... already been translated to first clinical pilot studies with encouraging results with the use of EPO as a neuroprotective agent ... Encouraging results with the use of EPO as a neuroprotective agent have been recently reported in clinical pilot studies after ... Erythropoietin: a multimodal neuroprotective agent. Exp & Trans Stroke Med 1, 4 (2009). https://doi.org/10.1186/2040-7378-1-4 ... The neuroprotective actions of EPO can be separated from its hematopoietic actions, a fact that is of value for therapeutic ...

"Diketopiperazines as neuroprotective agents". Mini Reviews in Medicinal Chemistry. 12 (1): 2-12. doi:10.2174/138955712798868959 ... Derivatives of cyclo(L-His-L-Pro) have been studied extensively to develop therapeutic agents for neurodegeneration. These ... The unsaturated derivatives are illustrated by phenylahistin the anti-cancer microtubule binding agent, and the mycotoxin ... an antibacterial agent used as food additives to prevent diarrhea in animals while the thio derivatives such as the cytotoxic ...

... has role neuroprotective agent (CHEBI:63726) choline alfoscerate (CHEBI:16870) has role ... neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. ...

... has role neuroprotective agent (CHEBI:63726) CDP-choline (CHEBI:16436) has role psychotropic drug ( ... neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. ...

Neuroprotective Agents * Neurotoxins * Calcium-Calmodulin-Dependent Protein Kinase Type 2 * Calcium-Calmodulin-Dependent ...

Special Issue in Molecules: Neuroprotective Agents to Treat Dementias. Special Issue in Molecules: New Synthetic Methodology ... Interests: drug discovery; multitarget ligands; antioxidants; neuroprotective agents; autophagy; anticancer; kinase inhibitor. ... as well as neuroprotective and anticancer agents. Besides, due to their straightforward preparation and intrinsic chemical ... Special Issue in Molecules: Nature-Inspired Antitumor Agents. Special Issue in Molecules: Recent Contributions of Female ...

... clinical drug as a procognitive agent with high in vivo potency and with GABAA potentiating activity for use in dementia. ... Re-engineering a neuroprotective, clinical drug as a procognitive agent with high in vivo potency and with GABAA potentiating ... with neuroprotective and anti-inflammatory properties via addition of nitric oxide (NO) and cGMP signaling property. RESULTS: ... that NMZ embodies a promising pharmacological approach targeting synaptic dysfunction and opens new avenues for neuroprotective ...

... Novel Neuroprotective Agent Promising in Stroke Medscape Medical News, February 9, 2023 ...

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Neuroprotective Agents, Prophylactic Agents ... Riboflavin is a potential neuroprotective agent affecting a wide range of neurological disorders.Dec 31, 2016. ... Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Prophylactic Agents. Additional Keywords : Natural Substance ... Pharmacological Actions : Analgesics, Prophylactic Agents. Additional Keywords : Analgesics, Coenzyme Q10, Headache: Migraine, ...

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Neuroprotective Agents. [+] Korean red ginseng ... Pharmacological Actions : Antihypertensive Agents, Nitric Oxide Enhancer, Vasodilator Agents. Additional Keywords : Plant ... Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative , Immunomodulatory. Additional Keywords : Plant Extracts ... Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, ...

Neuroprotective Agents. Gray NE, Morré J, Kelley J, Maier CS, Stevens JF, Quinn JF, Soumyanath A. 2014. Caffeoylquinic acids in ...

Cannabinoids as Neuroprotective Agents in Traumatic Brain Injury. Journal: Current Pharmaceutical Design. Volume: 10 Issue: 1 ... The Expression of Activity-Dependent Neuroprotective Protein (ADNP) is Regulated by Brain Damage and Treatment of Mice with the ... Poly (D,L-Lactide-co-Glycolide) Nanoparticles Loaded with Cerebrolysin Display Neuroprotective Activity in a Rat Model of ...

Table 1-6: Neuroprotective nanoparticles. Table 2-1: A classification of neuroprotective agents. Table 2-2: The neuroprotective ... Table 3-5: Neuroprotective gene therapy in animal stroke models. Table 3-6: Neuroprotective agents in clinical development for ... Table 11-16: Agents for neuroprotection of the peripheral nervous system. Table 11-17: Neuroprotective agents for chemotherapy- ... Table 7-7: Evaluation of neuroprotective agents for PD. Table 8-1: Relation of mutations in amyloid precursor protein to CNS ...

LR: 20131121; CI: Copyright (c) 2011; JID: 8004872; 0 (Neuroprotective Agents); 1406-18-4 (Vitamin E); EC 1.11.1.6 (Catalase); ... The neuroprotective effect of vitamin E on chronic sleep deprivation-induced memory impairment: the role of oxidative stress ... Vitamin E, on the other hand, is a strong antioxidant that has neuroprotective effect on the brain. In this study, we examined ...

Development of neuroprotective agents for use during surgery warrants further study.. Management of these potentially ...

Astrocytes produce the antiinflammatory and neuroprotective agent hydrogen sulfide. Neurobiol. Aging 30, 1523-1534. doi: ... which was demonstrated to not only have neuroprotective properties (Lee et al., 2009), but also act as neuromodulator in ...

Immunomodulator such as fingolimod or dexamethasone are neuroprotective agents. However, to apply new treatments of ICH in ... is a neuroprotective agent for ICH treatment, as it can reduce stroke volume, edema, degenerating neurons, and neurobehavioral ... it may be a neuroprotective agent [94]. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a key transcriptional factor for ... and it may be a neuroprotective agent for ICH [85]. Both argatroban or cycloheximide can prevent thrombin cytotoxicity and ...

Our data imply that maltol may offer a new powerful neuroprotective or neuroregenerative therapeutic agent for oxidative stress ... Maltol has potential as a new neuroprotective therapeutic agent for oxidative stress-related ocular diseases, including ... These neuroprotective and neurite outgrowth effects of maltol seemed to be related to the NF-κB inactivation. When the RGCs ... Neuroprotective and neurite outgrowth effects of maltol on retinal ganglion cells under oxidative stress. Samin Hong, Yoko ...

... we made an attempt to clearly describe the beneficial effects of various types of berries as promising neuroprotective agents. ... we made an attempt to clearly describe the beneficial effects of various types of berries as promising neuroprotective agents. ... Neuroprotective effects of berry fruits on neurodegenerative diseases : Neural Regeneration Research. You may be trying to ... Neuroprotective effects of berry fruits on neurodegenerative diseases. Subash, Selvaraju1,2; Essa, Musthafa Mohamed Ph.D.1,2,; ...

2020). Medicinal plants and natural products as neuroprotective agents in age-related macular degeneration.. https://www.ncbi. ...

... pharmacological and neuroprotective therapies, improve the health of people living with DCM? ... Role of neuroprotective perioperative means. What would be the role of steroids, neurotropic agents like pregabalin and ... Neuroprotective strategies during decompressive surgery for DCM. ARE ALTERNATIVE MEDICINES ANY USE, EG CANNABIS?. Is stem cell ... Are there adjunct neuroprotective/medical strategies to help improve outcome with surgical decompression?. Are we close to ...

Combined Anti-inflammatory and Neuroprotective Treatments Have the Potential to Impact Disease Phenotypes in Cln3−/− Mice. ...

Clinical trials of a variety of putative neuroprotective agents have been carried out. These include trials of the glutamate ... Neuroprotective effects of creatine in a transgenic mouse model of Huntingtons disease. J. Neurosci. 2000. 20:4389-4397. View ... R6 mice have been treated with a variety of agents, including free radical scavengers, glutamate antagonists, creatine, and ...

Isoflurane, the anesthetic agent used during MCAO surgeries, was previously shown to potentiate TRPA1 activity (Matta et al., ... All pharmacological agents (4-HNE, A967079, PEG-SOD, mitoTEMPO, extracellular SOD and apocynin) were administered via the ... However, there is a tendency to assume that pharmacological agents will work "as stated on the tin". I have the following ... However, there is a tendency to assume that pharmacological agents will work "as stated on the tin". I have the following ...