Inhibition of receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast formation by pyrroloquinoline quinine ...
... on receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast formation was examined using RAW 264.7 macrophage- ... NFATC Transcription Factors / antagonists & inhibitors* * NFATC Transcription Factors / metabolism * Osteoclasts / cytology* * ... PQQ inhibited the activation of nuclear factor of activated T cells (NFATc1), a key transcription factor of osteoclastogenesis ... The effect of pyrroloquinoline quinine (PQQ) on receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast ...
Characterization of a novel multifunctional resveratrol derivative for the treatment of atrial fibrillation
Calcineurin - Wikipedia
Calcineurin activates nuclear factor of activated T cell cytoplasmic (NFATc), a transcription factor, by dephosphorylating it. ... Calcineurin induces transcription factors (NFATs) that are important in the transcription of IL-2 genes. IL-2 activates T- ... Shibasaki F, Kondo E, Akagi T, McKeon F (1997). "Suppression of signalling through transcription factor NF-AT by interactions ... The activated NFATc is then translocated into the nucleus, where it upregulates the expression of interleukin 2 (IL-2), which, ...
NR2F6 protein expression summary - The Human Protein Atlas
Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional ... Enables DNA-binding transcription factor activity and sequence-specific double-stranded DNA binding activity. Involved in ... Transcription, Transcription regulation. Ligand (UniProt)i Keywords assigned by UniProt to proteins because they bind, are ... Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that ...
Pytel, Peter | Profiles RNS
DeCS
Transcription Factor NF AT Transcription Factor NF-AT Transcription Factors, NFATC NFAT Transcription Factor 4 - Narrower ... Transcription Factor, NFATC2. Transcription Factor, NFATC3. Transcription Factor, NFATC4. Transcription Factors, NFATC. ... NFAT Transcription Factor 2. NFAT Transcription Factor 3. NFAT Transcription Factor 4. NFAT Transcription Factor 5. NFAT-1 ... Facteurs de transcription NFATC Entry term(s):. Factor, NFATC1 Transcription. Factor, NFATC2 Transcription. Factor, NFATC3 ...
Downregulation of NFAT3 Due to Lack of T-Box Transcription Factor TBX5 Is Crucial for Cytokine Expression in T Cells | The...
The NFAT family transcription factors play crucial roles in immunological and other biological activities. NFAT3 is rarely ... Identification of amino acid residues and protein kinases involved in the regulation of NFATc subcellular localization. ... 5C). We found two transcription factor binding elements, T-box factor binding element (TBE) and NK-2 transcription factor- ... The binding sites of T-box transcription factor TBX5 and NK-2 transcription factor-related locus 5 Nkx2.5, which were expressed ...
Medicina - Research output - Universidad de los Andes
Ferdous, A.<...
Chi-Ying F. Huang - 研究成果 - 國立陽明交通大學研發
NFATC Transcription Factors 21% 23 引文 斯高帕斯(Scopus) ... is a marker of poor clinical outcomes that promotes metastasis of lung cancer by downregulating the transcription factor ATF3. ... Insulin-like growth factor 1 mediates 5-fluorouracil chemoresistance in esophageal carcinoma cells through increasing survivin ...
Jeffrey Langland - Scholarly Works - Arizona State University
Nuclear Factor 90 Proteins 100% * eIF-2 Kinase 75% * NFATC Transcription Factors 70% ... Nuclear factor-90 of activated T-cells: A double-stranded RNA-binding protein and substrate for the double-stranded RNA- ... Regulation of IL-2 gene expression and nuclear factor-90 translocation in vaccinia virus-infected cells. Langland, J., Kao, P. ...
In vivo cardiac gene transfer of Kv4.3 abrogates the hypertrophic response in rats after aortic stenosis - Fingerprint -...
Facultad de Medicina - Research output - Universidad de los Andes
Lan Peng - Research output - University of Texas Southwestern Medical Center
NFATC Transcription Factors 100% * Microarrays 80% * Osteoclasts 77% * Osteogenesis 65% * Block Like Crystal 50% ... Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos. Matsuo, K., Galson, D. L., ... Expression of insulin-like growth factors (IGFs) and IGF signaling: molecular complexity in uterine leiomyomas. Peng, L., Wen, ...
Department of Obstetrics and Gynecology - Research output - Penn State
Baoan D Ji - Research output - Mayo Clinic
Johnson, S. M.<...
NFATC Transcription Factors Medicine & Life Sciences 56% * Phosphatidylinositol 3-Kinase Medicine & Life Sciences 53% ... Nuclear factor of activated T cells (NFAT) signaling regulates PTEN expression and intestinal cell differentiation. Wang, Q., ...
NFAT - RHR - β-Scaffold Factors - Transcription Factors - Products
The NFAT family consists of five members: NFAT1 (also known as NFATp or NFATc2), NFAT2 (also known as NFATc or NFATc1), NFAT3 ( ... Proteins belonging to the NFAT (nuclear factor of activated T cells) family of transcription factors play a central role in ... Transcription factors of the NFAT family: regulation and function. Annu Rev Immunol. 1997;15:707-47. ... inducible gene transcription during the immune response[1]. ...
Gomez, M. F.<...
Transcriptional regulation of bone and joint remodeling by NFAT<...
NFATC Transcription Factors Medicine & Life Sciences 100% * Bone Remodeling Medicine & Life Sciences 76% ... The nuclear factor of activated T cells (NFAT) transcription factor family controls diverse biologic processes in vertebrates. ... The nuclear factor of activated T cells (NFAT) transcription factor family controls diverse biologic processes in vertebrates. ... The nuclear factor of activated T cells (NFAT) transcription factor family controls diverse biologic processes in vertebrates. ...
Intestinal bile acid composition modulates prohormone convertase 1β (PC1/3) expression and consequent GLP-1 production in male...
NFATC Transcription Factors Medicine & Life Sciences 11% * Dipeptidyl-Peptidase IV Inhibitors Medicine & Life Sciences 11% ... Furthermore, we demonstrate that nuclear factor of activated T cells mediates the TGR5-triggered PC1/3 gene expression. ... Furthermore, we demonstrate that nuclear factor of activated T cells mediates the TGR5-triggered PC1/3 gene expression. ... Furthermore, we demonstrate that nuclear factor of activated T cells mediates the TGR5-triggered PC1/3 gene expression. ...
PRIME PubMed | NFAT regulation of cystathionine γ-lyase expression in endothelial cells is impaired in rats exposed to...
CulturedCystathionine gamma-LyaseEndothelial CellsHydrogen SulfideHypoxiaMaleMesenteric ArteriesNFATC Transcription FactorsRats ... NOTEWORTHY This study identifies the calcium-regulated transcription factor nuclear factor of activated T cells as a novel ... NOTEWORTHY This study identifies the calcium-regulated transcription factor nuclear factor of activated T cells as a novel ... Sleep apnea is a risk factor for cardiovascular disease, and intermittent hypoxia (IH, 20 episodes/h of 5% O2-5% CO2 for 7 h/ ...
Rachel Groth | Graduate Program in Neuroscience
Recently, members of the NFATc family of transcription factors have also been implicated in shaping long-term changes in ... nuclear factor of activated T-cells)-dependent transcription: a role for the transcription factor NFATc4 in neurotrophin- ... Intriguingly, neurotrophin signaling appears ideally suited to activate NFATc transcription factors. As such, the experiments ... by examining the role of NFATc transcription factors in neurotrophin-mediated gene expression in vitro and in a model of ...
HKU Scholars Hub: Browsing DSpace
Nuclear Factor 90 Proteins | Profiles RNS
A family of double-stranded RNA-binding proteins that are related to NFATC TRANSCRIPTION FACTORS. In addition to binding to RNA ... nuclear factor 90 proteins form heterodimeric complexes that regulate GENETIC TRANSCRIPTION and may play a role in T-CELL ... "Nuclear Factor 90 Proteins" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... This graph shows the total number of publications written about "Nuclear Factor 90 Proteins" by people in this website by year ...
Allison Keeler-Klunk's research topics | Profiles RNS
The small muscle-specific protein Csl modifies cell shape and promotes myocyte fusion in an insulin-like growth factor 1...
The activities of transcription factors nuclear factor of activated T cells (NFAT) and myocyte enhancer-binding factor (MEF)2, ... The dynamic cytoskeletal localization of Csl and its dominant effects on cell shape and behavior and transcription factor ... Csl-expressing myoblasts differentiated and fused normally, although in the presence of insulin-like growth factor (IGF)-1 they ... in a screen for transcriptional targets of the cardiac homeodomain factor Nkx2-5. Csl transcripts were detected in atria and ...
Different agonists recruit different stromal interaction molecule proteins to support cytoplasmic Ca2+ oscillations and gene...
... dependent nuclear factor of activated T cells (NFAT)-driven gene expression are all exclusively maintained by the endoplasmic ... NFATC Transcription Factors, Rats, Receptors, Leukotriene, Stromal Interaction Molecule 1, Stromal Interaction Molecule 2 ... dependent nuclear factor of activated T cells (NFAT)-driven gene expression are all exclusively maintained by the endoplasmic ...
KEPE--a motif frequently superimposed on sumoylation sites in metazoan chromatin proteins and transcription factors. -...
MAF and NFATC families; chromatin modifiers like CHD-8, HDAC4 and DNA Top1; and the transcriptional regulatory kinases HIPK1 ... These candidates were particularly enriched in transcription factors, including FOS, JUN, Hif-1alpha, MLL2 and members of the ... This revealed significant enrichment of the motif using different Gene Ontology terms (e.g. transcription) that pertain to ... KEPE--a motif frequently superimposed on sumoylation sites in metazoan chromatin proteins and transcription factors. ...
Fagocitose
... inducing calcineurin-dependent nuclear translocation of the transcription factor NFATc. This selectively augments the ... MyD88 and transcription factor NFκB, and effector functions of pro-inflammatory cytokine, such as IL-1ß and TNF-α. ... and stimulates NFATc-controlled production of Syk-dependent cytokines. Our study thus identifies the CR3-Syk-NFATc axis as a ... Among the factors suspected to play a role are phenolic glycolipids (PGLs), produced notably by the major pathogenic species ...