Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5...
Myocytes, Smooth Muscle / cytology * Myocytes, Smooth Muscle / drug effects* * Myocytes, Smooth Muscle / metabolism ... Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5 ... and vascular smooth muscle cells (SMCs), which expressed EDG-5 protein weakly and abundantly, respectively. This ...
Iris sphincter muscle - Wikipedia
This structure is found in vertebrates and in some cephalopods.[citation needed] All the myocytes are of the smooth muscle type ... The iris sphincter muscle (pupillary sphincter, pupillary constrictor, circular muscle of iris, circular fibers) is a muscle in ... traveling between the sclera and the choroid to innervate the iris sphincter muscle. Iris dilator muscle Miosis Gest, Thomas R ... the muscle cells themselves are photosensitive causing iris action without brain input. It is controlled by parasympathetic ...
HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells
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JCI - New insights into the pathogenesis of asthma
Early investigators postulated that there was an intrinsic airway smooth muscle abnormality at the root of the asthmatic ... However, many studies with airway myocytes in culture have not corroborated this contention. This was followed by the ... There is impressive inflammation (I), mucus plugging (MP), subepithelial fibrosis (SF), myocyte hypertrophy and hyperplasia (MH ... myocyte hypertrophy and hyperplasia, and neovascularization are all readily appreciated in the asthmatic airway (Figure 1). ...
Increasing heart vascularisation after myocardial infarction using brain natriuretic peptide stimulation of endothelial and WT1...
In non-myocyte cells, endothelial and smooth muscle cells express PLB as explained above (point 6). We isolated these NMCs from ... In non-myocyte cells, endothelial and smooth muscle cells express PLB and BNP receptors. These cells can be directly stimulated ... It is well known than PLB is expressed by muscular cells such as cardiomyocytes and smooth muscle cells 3, 4. PLB is also ... It is well known than PLB is expressed by muscular cells such as cardiomyocytes and smooth muscle cells 3, 4. PLB is also ...
Potential Involvement of IL-17F in Asthma
... able to induce collagen synthesis and smooth muscle hyperplasia and is also a potent mitogen for fibroblasts and smooth muscle ... myofibroblasts and myocytes, and deposition of types I and III collagen [45]. IGF-I is ... Y. Chang, L. Al-Alwan, P.-A. Risse et al., "TH17 cytokines induce human airway smooth muscle cell migration," Journal of ... J. P. Noveral, A. Bhala, R. L. Hintz, M. M. Grunstein, and P. Cohen, "Insulin-like growth factor axis in airway smooth muscle ...
Kuntamallappanavar Guruprasad
is an author of over 20 publications in Steroids, Hormones, Channels, Myocytes, Ion Channels, Smooth Muscle and Patch-Clamp ...
Toxic Megacolon: Background, Pathophysiology, Etiology
NO is generated by macrophages and smooth muscles cells in the inflamed portions of the colon, inhibiting smooth muscle tone ... Neutrophils invade the muscle layer in toxic megacolon and directly damage the myocytes by the release of proteolytic enzymes, ... As inflammation progresses into the smooth-muscle layers of the colon, NO and local inflammatory modulators appear to be ... Induction of nitric oxide synthase in colonic smooth muscle from patients with toxic megacolon. Gastroenterology. 1995 Nov. 109 ...
Mechanisms of 5-Hydroxytryptamine2A Receptor Activation of the Mitogen-Activated Protein Kinase Pathway in Vascular Smooth...
In rat aortic myocytes, 5-HT (1 μM) activated Erk MAPK proteins 2- to 3-fold over basal values; activation was reduced by U0126 ... of 5-Hydroxytryptamine2A Receptor Activation of the Mitogen-Activated Protein Kinase Pathway in Vascular Smooth Muscle A. Banes ... of 5-Hydroxytryptamine2A Receptor Activation of the Mitogen-Activated Protein Kinase Pathway in Vascular Smooth Muscle A. Banes ... of 5-Hydroxytryptamine2A Receptor Activation of the Mitogen-Activated Protein Kinase Pathway in Vascular Smooth Muscle A. Banes ...
Treatment of Hypertension in the Elderly
... which controls smooth muscle contraction and cardiac myocyte contraction. By causing vascular smooth muscle relaxation, CCBs ... bind to L-type calcium channels on the vascular smooth muscle, cardiac myocytes, and cardiac nodal tissue. These channels are ... Dihydropyridines, because of their smooth muscle selectivity, are the CCBs mainly used to treat hypertension.18 ... block the effect of sympathetic nerves on blood vessels by binding to alpha-adrenoceptors located on the vascular smooth muscle ...
Cigarette smoke-induced MMP2 and MMP9 secretion from aortic vascular smooth cells is mediated via the Jak/Stat pathway.
We observed through zymograms that treatment of male rat aortic vascular smooth muscle cells (RASMC) with an aqueous extract of ... Myocytes, Smooth Muscle. *Matrix Metalloproteinase 9. *Matrix Metalloproteinase 2. *Male. *Janus Kinase 2 ... Cigarette smoke-induced MMP2 and MMP9 secretion from aortic vascular smooth cells is mediated via the Jak/Stat pathway.. ... "Cigarette smoke-induced MMP2 and MMP9 secretion from aortic vascular smooth cells is mediated via the Jak/Stat pathway." Hum ...
Cholinesterase Inhibitors: Part 4: The Cholinergic Toxidrome Section 2: Nicotinic Acetylcholine Receptors | Environmental...
Guyton and Hall 2006) (See Figure 6 below) (Smooth muscle contraction is controlled by muscarinic receptors, which are ... that penetrate through the cell walls of post-synaptic nerves and myocytes at the skeletal neuromuscular junctions. ( ... The somatic nervous system (neuromuscular junctions in skeletal muscles).. *The sympathetic and parasympathetic nervous system ... Neuromuscular junctions of skeletal muscles. *Fasciculations and myotonic jerks, followed by weakness and paralysis. ...
Structural Determinants of Kv7.5 Potassium Channels That Confer Changes in Phosphatidylinositol 4,5-Bisphosphate (PIP2)...
They have well-established roles in the regulation of excitability of neurons, cardiac myocytes, and smooth muscle cells ( ... Smooth muscle cells commonly express two functional Kv7 α-subunits, Kv7.4 and Kv7.5, which have different sensitivities to ... 2018) Mechanisms of PKA-Dependent Potentiation of Kv7.5 Channel Activity in Human Airway Smooth Muscle Cells. Int J Mol Sci 19 ... 1993) Spontaneous Ca2+ spiking in a vascular smooth muscle cell line is independent of the release of intracellular Ca2+ stores ...
Personalized Medicines: Disruptive Technologies in Life Sciences | Corning
Separations | Free Full-Text | The Bright and Dark Sides of Reactive Oxygen Species Generated by Copper–Peptide Complexes
Publications Citing Globals Software - Laboratory for Fluorescence Dynamics
Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle. ... Here, we tested the hypothesis that in arterial myocytes the anchoring protein AKAP150 and protein kinase C (PKC) play a ... including smooth muscle. Although TRPV4 channels play a key role in regulating vascular tone, the mechanisms controlling Ca2+ ... Four different LPSs that differed in the size of the polar headgroup (i.e., LPS smooth , LPS-Ra , LPS-Rc , LPS-Rd) were ...
R. Kirk Riemer's Profile | Stanford Profiles
Like primary myocytes, SHM cells expressed the intermediate filament desmin and the contractile protein alpha smooth muscle ... Like primary myocytes, SHM cells expressed the intermediate filament desmin and the contractile protein alpha smooth muscle ... To 10(-4) M hexamethonium (ganglionic smooth muscle blocker) and 10(-4) M decamethonium (nicotinic blocker of striated muscle) ... Regulation of uterine smooth muscle function during gestation PEDIATRIC RESEARCH Riemer, R. K., Heymann, M. A. 1998; 44 (5): ...
OPUS at UTS: Search - Open Publications of UTS Scholars
5 Myocytes, Smooth Muscle * 4 11 Medical and Health Sciences *. next > Date issued ... Ask1 Inhibition Prevented Mitogen-Induced Human Airway Smooth Muscle Growth In Chronic Obstructive Pulmonary Disease. Kota, A; ... Apoptosis signal-regulating kinase 1 inhibition attenuates human airway smooth muscle growth and migration in chronic ... N-oxide in combination with formoterol enhances the antiinflammatory effect of dexamethasone in airway smooth muscle cells. ...
Standardized fraction of Xylocarpus moluccensis fruits improve vascular relaxation and plaque stability in dyslipidemic models...
OPUS at UTS: Search - Open Publications of UTS Scholars
2 Myocytes, Smooth Muscle * 2 Respiratory System * 1 Base Sequence * 1 Biochemistry & Molecular Biology ... Induction and regulation of matrix metalloproteinase-12 in human airway smooth muscle cells. Xie, S; Issa, R; Sukkar, MB; ... TGF-β regulates Nox4, MnSOD and catalase expression, and IL-6 release in airway smooth muscle cells. Michaeloudes, C; Sukkar, ...
HAPLN1, A Potential Promising Biomarker for Heart Failure | Research Square
The major function of ANP is to relax vascular smooth muscle and promote renal water-sodium excretion. Elevated levels of ANP ... NPPA, also known as atrial natriuretic peptide (ANP), is a peptide hormone synthesized and released by atrial myocytes. ... was adopted to evaluate the CSA of the myocytes and the percentage of collagen. ... two-dimensional images were acquired from the LV parasternal long axis and parasternal short-axis near the papillary muscles. ...
Mouse RAGE Alexa Fluor® 350-conjugated Antibody FAB11795U-100UG: R&D Systems
Mechanisms of Cardiovascular Development
... and smooth muscle cells. In order to more effectively study epicardial EMT in vitro, we developed several new methods for the ... We developed an improved protocol for isolating embryonic myocyte cells, for use in co-cultures with epicardial cells. This co- ... culture system allows investigation into the effects of myocyte derived soluble factors uponepicardial EMT and mesenchymal cell ...
TASK-1 (KCNK3) channels in the lung: from cell biology to clinical implications | European Respiratory Society
TASK-1 in pulmonary arterial smooth muscle cells. a) Regulation of TASK-1 in pulmonary arterial smooth muscle cells. ET-1: ... TASK-1/TASK-3 channels were also detected in human atrial cardiac myocytes [42, 86]. Upregulation of TASK-1 was reported in ... et al. Two-pore domain K channel, TASK-1, in pulmonary artery smooth muscle cells. Circ Res 2003; 93: 957-964. ... et al. Impact of TASK-1 in human pulmonary artery smooth muscle cells. Circ Res 2006; 98: 1072-1080. ...
Atheroprotective Pulsatile Flow Induces Ubiquitin-Proteasome-Mediated Degradation of Programmed Cell Death 4 in Endothelial...
... including vascular smooth muscle cells [9], [10], cardiac myocytes [11] and fibroblasts [12], and repressing contractile gene ... 2010) An essential role of PDCD4 in vascular smooth muscle cell apoptosis and proliferation: implications for vascular disease ... and in stretched human aortic smooth muscle cells [27]. However, here we found that neither overexpression of miR-21 by ... Participating in Proliferation and Apoptosis in Cultured Human Aortic Smooth Muscle Cells. PLoS One 7: e47657. * View Article ...