Tumor Suppressor Protein p53Tumor Suppressor ProteinsGenes, Tumor SuppressorVon Hippel-Lindau Tumor Suppressor ProteinMutationTumor Suppressor Protein p14ARFRetinoblastoma ProteinPoint MutationCell Line, TumorProto-Oncogene Proteins c-mdm2Mutation, MissenseMolecular Sequence DataGenes, p53Nuclear ProteinsProtein BindingDNA-Binding ProteinsBase SequenceCell LineTranscription FactorsGene Expression Regulation, NeoplasticApoptosisTransfectionNeurofibromin 2Amino Acid SequenceAdenomatous Polyposis Coli ProteinGenes, SuppressorCell CycleProto-Oncogene ProteinsCyclin-Dependent Kinase Inhibitor p16Promoter Regions, GeneticUbiquitin-Protein LigasesTumor Cells, CulturedSignal TransductionPTEN PhosphohydrolaseCell Cycle ProteinsCell Transformation, NeoplasticCyclin-Dependent Kinase Inhibitor p21Protein Structure, TertiaryTranscription, GeneticCell ProliferationPhosphorylationNeoplasm ProteinsRNA, MessengerNeoplasmsRepressor ProteinsCell DivisionProteinsLigasesDNA DamageBinding SitesSuppression, GeneticCyclinsBlotting, WesternTranscriptional ActivationFrameshift MutationE2F Transcription FactorsDown-RegulationTumor Markers, BiologicalGene DeletionCarrier ProteinsPolymerase Chain ReactionGerm-Line MutationDNA PrimersGene SilencingProtein-Serine-Threonine KinasesLoss of HeterozygosityRecombinant Fusion ProteinsReverse Transcriptase Polymerase Chain ReactionHeLa CellsFibroblastsGene Expression RegulationCells, CulturedDNA MethylationE2F1 Transcription FactorSuppressor of Cytokine Signaling ProteinsRNA InterferenceMembrane ProteinsDNA, NeoplasmTrans-ActivatorsKidney NeoplasmsExonsCell NucleusTranscription Factor DP1RNA, Small InterferingOncogene Proteins, ViralDNAWT1 ProteinsAllelesPapillomavirus E7 ProteinsDNA Mutational AnalysisPhenotypeImmunohistochemistryBreast NeoplasmsRetinoblastoma-Binding Protein 1Tumor BurdenRecombinant ProteinsModels, BiologicalRetinoblastoma-Like Protein p107Wilms TumorSequence Homology, Amino Acid