Interleukin 12 - Wikipedia
Wang KS, Frank DA, Ritz J (May 2000). "Interleukin-2 enhances the response of natural killer cells to interleukin-12 through up ... Interleukin 12 (IL-12) is an interleukin that is naturally produced by dendritic cells, macrophages, neutrophils, and human B- ... Interleukin 12 (IL-12) is produced by activated antigen-presenting cells (dendritic cells, macrophages). It promotes the ... Newport MJ, Holland SM, Levin M, Casanova JL (2007). "Inherited disorders of the interleukin-12/23-interferon gamma axis". In ...
Interleukin-12 in Treating Patients With AIDS-Related Kaposi's Sarcoma
Interleukin-12 may kill tumor cells by stopping blood flow to the tumor and by stimulating a persons white blood cells to kill ... Phase I/II Pilot Study of Interleukin-12 in Patients With AIDS-Associated Kaposis Sarcoma. Trial Phase:. Phase 1/Phase 2. ... interleukin-12 (IL-12) At least 3 weeks since prior interferon therapy At least 2 weeks. since prior cytokines or bone marrow ... Patients receive interleukin-12 (IL-12). subcutaneously twice a week (at least 3 days apart) for 6 months. Patients with stable ...
WHO EMRO | Interleukins 12 and 13 levels among beta-thalassaemia major patients | Volume 19, issue 2 | EMHJ volume 19, 2013
Interleukins 12 and 13 levels among beta-thalassaemia major patients ... Increased plasma levels of interleukin-6 and interleukin-8 in beta-thalassaemia major. Haematologia, 2001, 31:237-244. ... Increased plasma levels of interleukin-6 and interleukin-8 in beta-thalassaemia major. Haematologia, 2001, 31:237-244. ... Plasma interleukin-3 (IL-3) and IL-7 concentrations in children with homozygous beta-thalassemia. Journal of Tropical ...
EZClick - Interleukin 12
interleukin 12 23 antagonists interleukin 12 and 23 interleukin 12 and interleukin 23 interleukin 12 cpt code interleukin 12 ... deficiency interleukin 12 function interleukin 12 labcorp interleukin 12 lab test interleukin 12 p40 interleukin 12 protein ... interleukin 12 receptor interleukin 12 wikipedia interleukin 12/23 interleukin 12b interleukin 12p70 virus deaths by state ... Anti-Protein A:HRP, 12 ml (F911-12) * Naturally produced type I IFNs enhance human myeloid dendritic cell maturation and IL- ...
Gel-FAST - Interleukin 12
interleukin 12 23 antagonists interleukin 12 and 23 interleukin 12 and interleukin 23 interleukin 12 cpt code interleukin 12 ... deficiency interleukin 12 function interleukin 12 labcorp interleukin 12 lab test interleukin 12 p40 interleukin 12 protein ... interleukin 12 receptor interleukin 12 wikipedia interleukin 12/23 interleukin 12b interleukin 12p70 virus deaths by state ... Anti-Protein A:HRP, 12 ml (F911-12) * Naturally produced type I IFNs enhance human myeloid dendritic cell maturation and IL- ...
IL12RB1base: Interleukin-12 receptor β1 deficiency | Bioinformatics
Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) ( ... Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) ( ... Variation registry for Interleukin-12 receptor β1 deficiency Select database by name. ADAbase. AICDAbase. AIREbase. AK2base. ...
Multilineage hematopoietic recovery with concomitant antitumor effects using low dose Interleukin-12 in myelosuppressed tumor...
Interleukin-12 (IL-12) is a cytokine well known for its role in immunity. A lesser known function of IL-12 is its role in ... We have focused on the lesser known role of IL-12 in hematopoiesis and hypothesized that an important clinical role for IL-12 ... This putative clinical function of IL-12 focuses on the dual role of IL-12 in hematopoiesis and immunity. We assessed the ... Moreover, our protocol design utilizes single, low doses of IL-12 that did not yield any apparent toxicity. Our results portend ...
![IL12B interleukin 12B [Homo sapiens (human)] - Gene - NCBI](data:image/png;base64,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)
IL12B interleukin 12B [Homo sapiens (human)] - Gene - NCBI
Association between interleukin 12B and interleukin 23R gene polymorphisms and systemic lupus erythematosus: a meta-analysis. ... interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40). interleukin-12 beta ... Title: Association between interleukin 12B and interleukin 23R gene polymorphisms and systemic lupus erythematosus: a meta- ... IL12B interleukin 12B [Homo sapiens] IL12B interleukin 12B [Homo sapiens]. Gene ID:3593 ...
Interleukin-12 Subunit p35 | Profiles RNS
A subunit of interleukin-12. It binds to the INTERLEUKIN-12 SUBUNIT P40 via a disulfide bond that results in the active ... "Interleukin-12 Subunit p35" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... This graph shows the total number of publications written about "Interleukin-12 Subunit p35" by people in this website by year ... Below are the most recent publications written about "Interleukin-12 Subunit p35" by people in Profiles. ...
Interleukin 12 (IL12) 4CH - Drops - United Remedies
Biological Functions: Stimulation of the NK cells and T lymphocytes. Indications: For a regulating action on cell-mediated immune response. Dosage: 15-20 drops twice a day (standard dosage).
Interleukin 23 - wikidoc
Sedgwick JD (Feb 2003). "Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the ... Interleukin-23 (IL-23) is a heterodimeric cytokine composed of an IL12B (IL-12p40) subunit (that is shared with IL12) and the ... "Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12". Journal of Clinical Investigation. 110 ... "Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12". Journal of Experimental Medicine ...
Interleukin-10
- Interleukin 10
Summary Report | CureHunter
Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein. ... Interleukin-10: A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS; and ... Interleukin-10 (Interleukin 10). Subscribe to New Research on Interleukin-10 A cytokine produced by a variety of cell types, ... Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein. ...
IL-12 p70 (Interleukin-12 p70), Human (mammalian cell expression) - Biofargo
Update on the Management of Inflammatory Bowel Disease during Pregnancy and Breastfeeding | Digestion | Karger Publishers
Anti-Interleukin IL-12-23. Ustekinumab is an IgG1 monoclonal anti-interleukin 12-23 antibody approved for psoriasis, psoriatic ... Calcineurin inhibitors act by suppressing the production of interleukins 2 and 3, inhibiting chemotaxis of neutrophils and ... Data for anti-interleukin 12-23 and anti-integrin are very limited but due to limited transfer detectable and their monoclonal ... 12.. Van Assche G, Dignass A, Reinisch W, van der Woude CJ, Sturm A, De Vos M, et al.; European Crohns and Colitis ...
Interleukin-12 is dispensable for functional interferon (IFN)-gamma producing CD8+ cytotoxic T cells in Toxoplasma gondii...
Interleukin (IL)-12 is a proinflammatory cytokine generally regarded as a master regulator of type 1 T cell mediated immunity ... Interleukin (IL)-12 is a proinflammatory cytokine generally regarded as a master regulator of type 1 T cell mediated immunity ... Interleukin-12 is dispensable for functional interferon (IFN)-gamma producing CD8+ cytotoxic T cells in Toxoplasma gondii ... Interleukin-12 is dispensable for functional interferon (IFN)-gamma producing CD8+ cytotoxic T cells in Toxoplasma gondii ...
Frontiers | A Two-Phase Expansion Protocol Combining Interleukin (IL)-15 and IL-21 Improves Natural Killer Cell Proliferation...
Keywords: natural killer cells, radiotherapy, rhabdomyosarcoma, RH30 cells, RD cells, interleukin-15, interleukin-21 ... Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor. J Exp ... Trinchieri G. Interleukin-12 and its role in the generation of TH1 cells. Immunol Today (1993) 14:335-8. doi:10.1016/0167-5699( ... Lin S-J, Wang L-Y, Huang Y-J, Kuo M-L. Effect of interleukin (IL)-12 and IL-15 on apoptosis and proliferation of umbilical cord ...
WikiGenes - IL16 - interleukin 16
Interleukin-16 (IL-16) can cause the high affinity of IL-2 receptors on CD4+ cells and is chemotaxis to Th1 cells and CD4+ T ... Interleukin-16 (IL-16) is secreted by activated CD8+ T lymphocytes and acts on CD4+ T lymphocytes, monocytes and eosinophils [8 ... Expression of interleukin-16 by microglial cells in inflammatory, autoimmune, and degenerative lesions of the rat brain. Guo, L ... Assignment of human interleukin 16 (IL16) to chromosome 15q26.3 by radiation hybrid mapping. Kim, H.S. Cytogenet. Cell Genet. ( ...
Guinea pig IL18(Interleukin 18) ELISA Kit - iBiomagazine
Description: A sandwich ELISA kit for detection of Interleukin 12B from Guinea pig in samples from blood, serum, plasma, cell ... Description: A sandwich ELISA kit for detection of Interleukin 18 from Guinea pig in samples from blood, serum, plasma, cell ... Description: A sandwich ELISA kit for detection of Interleukin 10 from Guinea pig in samples from blood, serum, plasma, cell ... Description: A sandwich ELISA kit for detection of Interleukin 18 from Pig in samples from blood, serum, plasma, cell culture ...
Psoriatic Arthritis Medication: Nonsteroidal anti-inflammatory drugs (NSAIDs), Oral small molecules (OSMs), TNF Inhibitors,...
Interleukin Inhibitors. Class Summary. Interleukin (IL)-12/IL-23p40, IL-23, and IL-17 receptors are associated with ... Secukinumab Inhibition of Interleukin-17A in Patients with Psoriatic Arthritis. N Engl J Med. 2015 Oct. 373 (14):1329-39. [QxMD ... Kimball AB, Gordon KB, Langley RG, Menter A, Chartash EK, Valdes J. Safety and efficacy of ABT-874, a fully human interleukin ... Ixekizumab, an interleukin-17A specific monoclonal antibody, for the treatment of biologic-naive patients with active psoriatic ...
Elevations of serum interleukin-12 concentrations in women with severe pre-eclampsia and HELLP syndrome. | J Reprod Immunol;31...
Elevations of serum interleukin-12 concentrations in women with severe pre-eclampsia and HELLP syndrome.. Dudley, D J; Hunter, ... Eleven women had elevations of serum IL-12 p75 dimer, and 10 of these 11 patients had severe pre-eclampsia or HELLP syndrome. ... It was found that serum IL-12 (p40 subunit) concentrations were elevated in women with both severe pre-eclampsia (p = 0.011) or ... While the exact role of IL-12 in hypertensive disease during pregnancy is unclear, our data support the hypothesis that the ...
MHC Class II Antigen Presentation by the Intestinal Epithelium Initiates Graft-versus-Host Disease and Is Influenced by the...
... interleukin-12; intestinal epithelial cells; microbiome; toll-like receptors; type 1 innate lymphoid cells. ... IL-12/23p40 neutralization prevented MHC class II upregulation on IECs and initiation of lethal GVHD in the GI tract. Thus, MHC ... 12 Envoi Specialist Pathologists, Brisbane, QLD 4006, Australia.. *13 Bone Marrow Transplantation Laboratory, Immunology ... IFNγ responses are characteristically driven by IL-12 secretion from myeloid cells. Antibiotic-mediated depletion of the ...
Table 1 - Poliovirus Excretion in Children with Primary Immunodeficiency Disorders, India - Volume 23, Number 10-October 2017 -...
Interleukin-15 induces IL-12 receptor β1 gene expression through PU.1 and IRF 3 by targeting chromatin remodeling<...
Interleukin-15 induces IL-12 receptor β1 gene expression through PU.1 and IRF 3 by targeting chromatin remodeling. In: Blood. ... Interleukin-12 receptor β1 (IL12RB1) is expressed on a variety of immune cells, including T and natural killer (NK) cells and ... N2 - Interleukin-12 receptor β1 (IL12RB1) is expressed on a variety of immune cells, including T and natural killer (NK) cells ... AB - Interleukin-12 receptor β1 (IL12RB1) is expressed on a variety of immune cells, including T and natural killer (NK) cells ...
Regulation of interleukin-12 gene expression and its anti-tumor activities by prostaglandin E2 derived from mammary carcinomas....
Regulation of interleukin-12 gene expression and its anti-tumor activities by prostaglandin E2 derived from mammary carcinomas. ... Regulation of interleukin-12 gene expression and its anti-tumor activities by prostaglandin E2 derived from mammary carcinomas. ... Interleukin-12 (IL-12)-mediated immune responses are critical for the control of malignant development. Tumors can actively ... Animals, Antineoplastic Agents, Cyclooxygenase 2, Dinoprostone, Female, Gene Expression Regulation, Neoplastic, Interleukin-12 ...
Plasma Interleukin-12 in Malaria-Tolerant Papua New Guineans: Inverse Correlation with Plasmodium falciparum Parasitemia and...
Adenovirus-mediated interleukin-12 gene transfer combined with cytosine deaminase followed by 5-fluorocytosine treatment exerts...
Interleukin-12 (IL-12), a heterodimeric immunoregulatory cytokine composed of covalently linked p35 and p40 subunits, has ... Ad.p35 plus Ad.p40, or Ad.IL-12, with or without Ad.CD, were administered (single-dose) intratumorally to Renca tumor-bearing ... Adenoviral vectors were constructed encoding one or both subunits of murine IL-12 (Ad.p35, Ad.p40 and Ad.IL-12) or cytosine ... Ad.CD/5-FC treatment significantly increased the antitumor effect of Ad.IL-12 in terms of tumor growth inhibition and mean ...
Spermine differentially regulates the production of interleukin-12 p40 and interleukin-10 and suppresses the release of the t...
IL-12 and IL-23 pathway inhibition in inflammatory bowel disease | Nature Reviews Gastroenterology & Hepatology
... and interleukin-23 (IL-23), which belong to the IL-12 family of cytokines, have a key role in intestinal homeostasis and ... IL-12 and IL-23 have been implicated in inflammatory bowel disease. In this Review, Vande Casteele and colleagues summarize the ... An increased understanding of these biological effects, particularly the pro-inflammatory effects mediated by IL-12 and IL ... and highlights IL-12- and IL-23-directed drug development for the treatment of Crohns disease and ulcerative colitis. ...
Low-dose exogenous interleukin (IL)-12 enhances antigen-induced interferon-γ production without affecting IL-10 production in...
keywords = "Bronchial asthma, Dermatophagoides farinae, Interferon-γ, Interleukin-10, Interleukin-12, Peripheral blood ... Background: Although interleukin (IL)-12, IL-10 and interferon (IFN)-γ are key cytokines that control the T helper (Th) 1/Th2 ... N2 - Background: Although interleukin (IL)-12, IL-10 and interferon (IFN)-γ are key cytokines that control the T helper (Th) 1/ ... AB - Background: Although interleukin (IL)-12, IL-10 and interferon (IFN)-γ are key cytokines that control the T helper (Th) 1/ ...