Copy-Number Variation of the Glucose Transporter Gene SLC2A3 and Congenital Heart Defects in the 22q11.2 Deletion Syndrome -...
Approximately 65% of individuals with 22q11DS have a congenital heart defect (CHD), mostly of the conotruncal type, and/ … ... Copy-Number Variation of the Glucose Transporter Gene SLC2A3 and Congenital Heart Defects in the 22q11.2 Deletion Syndrome ... Copy-Number Variation of the Glucose Transporter Gene SLC2A3 and Congenital Heart Defects in the 22q11.2 Deletion Syndrome ... Different Types of Deletions Created by Low-Copy Repeats Sequences Location in 22q11.2 Deletion Syndrome: Genotype-Phenotype ...
Angiogenesis In Urologic Malignancies
... glucose transporter type 1; HIF, hypoxia-inducible factor; MMP, matrix metalloproteinase; mRNA, messenger RNA; MVD, microvessel ... Glucose transporter: 1 A transmembrane glycoprotein involved in passive transport of glucose through cellular membranes ... 3 pg/ml predicts worse prognosis. Dosquet et al. (1997)[59] 117. Yes. Serum bFGF, VEGF, SF, E-selectin, and TNF-α. TNF-α ... 2006;3(3):157-169. © 2006 Nature Publishing Group Cite this: Mechanisms of Disease: Angiogenesis In Urologic Malignancies - ...
Publication Detail
Glucose - MeSH - NCBI
Glucose Transporter Type 1. A ubiquitously expressed glucose transporter that is important for constitutive, basal GLUCOSE ... Glucose Transporter Type 4. A glucose transport protein found in mature MUSCLE CELLS and ADIPOCYTES. It promotes transport of ... Glucose Transporter Type 2. A glucose transport facilitator that is expressed primarily in PANCREATIC BETA CELLS; LIVER; and ... Glucose Transporter Type 5. A hexose transporter that mediates FRUCTOSE transport in SKELETAL MUSCLE and ADIPOCYTES and is ...
SLC2A3 - Early...
glucose transporter type 3, brain. *solute carrier family 2 (facilitated glucose transporter), member 3 ... glucose binding activity; and glucose transmembrane transporter activity. Involved in glucose import across plasma membrane and ... solute carrier family 2, facilitated glucose transporter member 3. Description. From NCBI Gene: Enables dehydroascorbic acid ... Biomarker of Alzheimers disease; acanthosis nigricans; diabetes mellitus; and type 2 diabetes mellitus. [provided by Alliance ...
Biomarkers Search
2. Pharmacodynamics, efficacy and safety of sodium-glucose co-transporter type 2 (SGLT2) inhibitors for the treatment of type 2 ... The potential role of sodium glucose co-transporter 2 inhibitors in combination therapy for type 2 diabetes mellitus.. Lajara R ... Development of the sodium-glucose co-transporter 2 inhibitor dapagliflozin for the treatment of patients with type 2 diabetes ... 9. Sodium glucose co-transporter 2 inhibitors: blocking renal tubular reabsorption of glucose to improve glycaemic control in ...
Propranolol Inhibits Glucose Metabolism and 18F-FDG Uptake of Breast Cancer Through Posttranscriptional Downregulation of...
Relationship between FDG uptake and expressions of glucose transporter type 1, type 3, and hexokinase-II in Reed-Sternberg ... The tuberous sclerosis complex regulates trafficking of glucose transporters and glucose uptake. Am J Pathol. 2008;172:1748- ... can be an excellent tracer to visualize glucose metabolism and cancer lesions in the clinic. Glucose transporter-1 (GLUT-1) and ... 18F-FDG-PET of musculoskeletal tumors: a correlation with the expression of glucose transporter 1 and hexokinase II. Ann Nucl ...
Effect of ipragliflozin on liver function in Japanese type 2 diabetes mellitus patients: subgroup analysis of a 3-year post...
The STELLA-LONG TERM prospective post-marketing surveillance study assessed ipragliflozin in Japanese patients with type 2 ... diabetes mellitus (T2DM). This subgroup analysis of patients with liver impairment used the final 3-year results. Data on ... Sodium-Glucose Transporter 2 Inhibitors / administration & dosage* * Sodium-Glucose Transporter 2 Inhibitors / therapeutic use ... Effect of ipragliflozin on liver function in Japanese type 2 diabetes mellitus patients: subgroup analysis of a 3-year post- ...
Nerve tissue protein - Wikipedia
Dopamine and cAMP-Regulated Phosphoprotein 32 Fragile X Mental Retardation Protein GAP-43 Protein Glucose Transporter Type 3 Hu ... There are two types of myelin. The first is oligodendrocyte, which can be found in the mammalian Central Nervous System (CNS). ... In caspase-3 the hook and sinker attach. Both the BIR2 and BIR3 have a groove that is predominately negatively charged. ... 3 (6): 401-10. doi:10.1038/nrm830. PMID 12042762. S2CID 15238683. Lindholm, Dan; Mercer, Eric A; Yu, Li-Ying; Chen, Yuming; ...
Isolation, characterization and expression analysis of a hypoxia-responsive glucose transporter gene from the grass carp,...
2017-2021 NIDCD Strategic Plan | NIDCD
Glucose transporters and ATP-gated K+ (KATP) metabolic sensors are present in type 1 taste receptor 3 (T1r3)-expressing taste ... These types of communication problems are a strong predictor of increased isolation and poor quality of life.208 The NIDCD ... However, other types of odors also affect the way humans interact. For example, people with smell loss may exhibit poor hygiene ... Unmyelinated type II afferent neurons report cochlear damage. Proc Natl Acad Sci U S A. 2015;112(47):14723-7. doi: 10.1073/pnas ...
Association Between Anthropometric Risk Factors and Metabolic Syndrome Among Adults in India: A Systematic Review and Meta...
... and in the enhancement of glucose transporter type 4 translocation and glucose transport during the stimulation of skeletal ... Fasting blood glucose: ≥5.6 mmol/L, treatment for elevated blood glucose, or previously diagnosed type 2 diabetes ... Fasting blood glucose: ≥5.6 mmol/L, treatment for elevated blood glucose, or previously diagnosed type 2 diabetes ... Author, year, typea. State, region, type. Setting, participant sexb. Age, y. Sample size. Criteria for exposure (criteria for ...
DeCS
Glucose Transporter Type 3 Entry term(s). GLUT 3 Protein GLUT-3 Protein GLUT3 Protein SLC2A3 Protein Solute Carrier Family 2, ... 2006; GLUCOSE TRANSPORTER TYPE 3 was indexed under MONOSACCHARIDE TRANSPORT PROTEINS & NERVE TISSUE PROTEINS 2005, & under ... Transporteur de glucose de type 3 Entry term(s):. GLUT 3 Protein. GLUT-3 Protein. GLUT3 Protein. SLC2A3 Protein. Solute Carrier ... A major glucose transporter found in NEURONS.. Allowable Qualifiers:. AD administration & dosage. AE adverse effects. AG ...
MeSH Browser
A major glucose transporter found in NEURONS.. Terms. Glucose Transporter Type 3 Preferred Term Term UI T629090. Date01/28/2005 ... Glucose Transport Proteins, Facilitative [D12.776.157.530.500.500] * Glucose Transporter Type 1 [D12.776.157.530.500.500.500] ... Glucose Transport Proteins, Facilitative [D12.776.157.530.937.563] * Glucose Transporter Type 1 [D12.776.157.530.937.563.500] ... Glucose Transport Proteins, Facilitative [D12.776.543.585.500.500] * Glucose Transporter Type 1 [D12.776.543.585.500.500.500] ...
MeSH Browser
A major glucose transporter found in NEURONS.. Terms. Glucose Transporter Type 3 Preferred Term Term UI T629090. Date01/28/2005 ... Glucose Transport Proteins, Facilitative [D12.776.157.530.500.500] * Glucose Transporter Type 1 [D12.776.157.530.500.500.500] ... Glucose Transport Proteins, Facilitative [D12.776.157.530.937.563] * Glucose Transporter Type 1 [D12.776.157.530.937.563.500] ... Glucose Transport Proteins, Facilitative [D12.776.543.585.500.500] * Glucose Transporter Type 1 [D12.776.543.585.500.500.500] ...
Insulin Resistance and Environmental Pollutants: Experimental Evidence and Future Perspectives | Environmental Health...
... "adipose-type" and "brain-type" glucose transporters in mice. Mol Pharmacol 47:65-737530807. Medline, Google Scholar ... Bisphenol A affects glucose transport in mouse 3T3-F442A adipocytes. Br J Pharmacol 141:209-21414707028. Crossref, Medline, ... Cadmium induces impaired glucose tolerance in rat by down-regulating GLUT4 expression in adipocytes. Arch Biochem Biophys 413: ... Environmental pollutants and type 2 diabetes: a review of mechanisms that can disrupt beta cell function. Diabetologia 54:1273- ...
Type Ib Glycogen Storage Disease Treatment & Management: Medical and Surgical Care, Diet
These enzymes normally catalyze reactions that ultimately convert glycogen compounds to glucose. ... Glycogen storage disease type Ib: role of glucose-6-phosphate transporter in cell metabolism and function. FEBS Lett. 2020 Jan ... encoded search term (Type Ib Glycogen Storage Disease) and Type Ib Glycogen Storage Disease What to Read Next on Medscape ... Structure-function study of the glucose-6-phosphate transporter, an eukaryotic antiporter deficient in glycogen storage disease ...
Nicholas Davidson - Research output - Research Profiles at Washington University School of Medicine
Human intestinal glucose transporter expression and localization of GLUT5. Davidson, N. O., Hausman, A. M. L., Ifkovits, C. A. ... Increased Risk of Colorectal Cancer in Type 2 Diabetes Is Independent of Diet Quality. Jarvandi, S., Davidson, N. O. & ... GLUT3 glucose transporter isoform in rat testis: Localization, effect of diabetes mellitus, and comparison to human testis. ... Influence of lifestyle factors on inflammation in men and women with type 2 diabetes: Results: From the national health and ...
Red rice|em| koji|/em| extract alleviates hyperglycemia by increasing glucose uptake and glucose transporter type 4 levels in...
The protein expression levels of glucose transporter type 4 (GLUT4) in the skeletal muscle and glucose transporter type 2 ( ... Red rice koji extract alleviates hyperglycemia by increasing glucose uptake and glucose transporter type 4 levels in skeletal ... extract alleviates hyperglycemia by increasing glucose uptake and glucose transporter type 4 levels in skeletal muscle in two ... Level of skeletal muscle glucose transporter protein correlates with insulin-stimulated whole body glucose disposal in man. ...
Leukocyte Adhesion Deficiency - Immunology; Allergic Disorders - MSD Manual Professional Edition
Type 2 results from mutations in the glucose diphosphate (GDP)-fucose transporter gene. Type 3 is caused by mutations in the ... Type 1 results from mutations in the integrin beta-2 gene (ITGB2), encoding CD18 beta-2 integrins. ... For patients with type 2 leukocyte adhesion deficiency, correcting the underlying defect with fucose supplementation should be ... Leukocyte adhesion deficiency 3: Defective activation of all beta integrins (1, 2, and 3) ...
Type Ib Glycogen Storage Disease Differential Diagnoses
These enzymes normally catalyze reactions that ultimately convert glycogen compounds to glucose. ... Glycogen storage disease type Ib: role of glucose-6-phosphate transporter in cell metabolism and function. FEBS Lett. 2020 Jan ... encoded search term (Type Ib Glycogen Storage Disease) and Type Ib Glycogen Storage Disease What to Read Next on Medscape ... Structure-function study of the glucose-6-phosphate transporter, an eukaryotic antiporter deficient in glycogen storage disease ...
The Role of Dysregulated Glucose Metabolism in Epithelial Ovarian Cancer
Preliminary reports suggest that these drugs not only reduce available plasma glucose, but also have direct effects on cancer ... The Warburg Effect describes the ability of fast-growing cancer cells to preferentially metabolize glucose via anaerobic ... which are associated with dysglycemia and increased blood glucose. ... H. K. Shim, W. W. Lee, S. Y. Park, H. Kim, Y. So, and S. E. Kim, "Expressions of glucose transporter types 1 and 3 and ...
Volume 28 (2015): Issue 3 (September 2015)
... sodium-glucose co-transporter type 1 (SGLT1), and sodium-glucose co-transporter type type 2 (SGLT2) - this being located in the ... sodium-glucose co-transporter type 1 (SGLT1), and sodium-glucose co-transporter type type 2 (SGLT2) - this being located in the ... Flozins, inhibitors of type 2 renal sodium-glucose co-transporter - not only antihyperglycemic drugs. Grzegorz Mizerski, ... Flozins, inhibitors of type 2 renal sodium-glucose co-transporter - not only antihyperglycemic drugs. Grzegorz Mizerski, ...
Type Ib Glycogen Storage Disease: Practice Essentials, Background, Pathophysiology
These enzymes normally catalyze reactions that ultimately convert glycogen compounds to glucose. ... type Ia and type Ib. GSD type Ib is caused by a mutation in the glucose-6-phosphate transporter gene (G6PT1, also known as ... GSD type Ia, glucose-6-phosphatase deficiency or type Ib, glucose-6-phosphate transporter mutation). The remaining GSDs are not ... GSD type Ib is an autosomal recessive condition caused by a mutation in the glucose-6-phosphate transporter gene (G6PT1, also ...
Cells | Free Full-Text | Hypoxia Dictates Metabolic Rewiring of Tumors: Implications for Chemoresistance
... increased expression of drug efflux transporters, stemness maintenance, and epithelial-mesenchymal transition) cooperate in ... The increase in glucose and amino acid uptake, glycolytic flux, and lactate production; the alterations in glutamine metabolism ... and urokinase-type plasminogen activator (uPA) [46,47], the glucose-metabolizing enzymes-glucose transporters 1 and 3 (GLUT1 ... Na+-coupled glucose transporters (SGLTs) contribute to glucose uptake in non-transformed cells, but they are not modified by ...
S100 Proteins | Harvard Catalyst Profiles | Harvard Catalyst
Search All Tech Briefings - Page 3 - NIHR
Glucose transporter type 1 deficiency syndrome Glycogen storage disease type 1a GM1 gangliosidosis GM2 gangliosidosis Graft ... Type 1 diabetes Type 2 diabetes Ulcerative colitis Ulcerative proctitis Uncontrolled bleeding Upper limb spasticity Urinary ... Molybdenum cofactor deficiency Type A Monocarboxylate transporter 8 deficiency (Allan-Herndon-Dudley syndrome) Motor neurone ... Mucopolysaccharidosis type IIIB (Sanfilippo B syndrome) Mucopolysaccharidosis type VII Multiple myeloma (MM) Multiple sclerosis ...
Diabetes, Obesity and Metabolism: Vol 23, No 3
... a dual sodium-glucose co-transporter (SGLT)1 and SGLT2 inhibitor, to optimized insulin therapy in adults with type 1 diabetes ... safety of sodium-glucose co-transporter-2 inhibitors compared with dipeptidyl peptidase-4 inhibitors in older adults with type ... Comparative efficacy and safety of glucose-lowering drugs as adjunctive therapy for adults with type 1 diabetes: A systematic ... The cover image is based on the Original Article Dose-dependent accumulation of glucose in the intestinal wall and lumen ...
Role of PI3K/AKT Pathway in Insulin-Mediated Glucose Uptake | IntechOpen
This powerful anabolic hormone regulates the transport of glucose into the cell through translocation of glucose transporter ... We will present regulatory mechanisms and modulators of insulin-mediated glucose uptake. ... Glucose uptake is regulated by several mechanisms, where insulin plays the most prominent role. ... starting with activation of insulin receptors through signaling cascade involving phosphatidylinositol 3-kinase (PI3K) and ...
SLC2A1 gene: MedlinePlus Genetics
The SLC2A1 gene provides instructions for producing a protein called the glucose transporter protein type 1 (GLUT1). Learn ... Klepper J. Impaired glucose transport into the brain: the expanding spectrum of glucose transporter type 1 deficiency syndrome ... Phenotypic spectrum of glucose transporter type 1 deficiency syndrome (Glut1 DS). Curr Neurol Neurosci Rep. 2013 Apr;13(4):342 ... The SLC2A1 gene provides instructions for producing a protein called the glucose transporter protein type 1 (GLUT1). The GLUT1 ...