What is the definition of Eukaryotic initiation factor 2b? | Dictionary.net
A guanine nucleotide exchange factor that acts to restore EIF-2 to its GTP bound form. ... EUKARYOTIC INITIATION FACTOR 2B \jˌuːkɐɹɪˈɒtɪk ɪnˌɪʃɪˈe͡ɪʃən fˈaktə tˈuː bˈiː], \jˌuːkɐɹɪˈɒtɪk ɪnˌɪʃɪˈeɪʃən fˈaktə tˈuː bˈiː ... eukaryotic initiation factor 2 * eukaryotic initiation factor 2alpha kinase *Eukaryotic Initiation Factor 2B ... A guanine nucleotide exchange factor that acts to restore EIF-2 to its GTP bound form. ...
EIF2B1 - Wikipedia
"Entrez Gene: EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa". Ewing RM, Chu P, Elisma F, Li H, ... "A novel interaction between adrenergic receptors and the alpha-subunit of eukaryotic initiation factor 2B". J. Biol. Chem. 272 ... "Ovarian Failure Related to Eukaryotic Initiation Factor 2B Mutations". Am. J. Hum. Genet. 72 (6): 1544-50. doi:10.1086/375404. ... ɛ Subunit of Eukaryotic Translation Initiation Factor 2B (eIF2Bɛ) Required for Guanine Nucleotide Exchange Reveals a Novel ...
EIF2B5 gene: MedlinePlus Genetics
eukaryotic translation initiation factor 2B, subunit 5 (epsilon, 82kD). *eukaryotic translation initiation factor 2B, subunit 5 ... Mutations linked to leukoencephalopathy with vanishing white matter impair the function of the eukaryotic initiation factor 2B ... Under other conditions, it slows protein synthesis by binding tightly to the initiation factor, which converts the eIF2B ... The eIF2 protein is called an initiation factor because it is involved in starting (initiating) protein synthesis. ...
Richardson JP, et al. (2004) | SGD
2004) Mutations causing childhood ataxia with central nervous system hypomyelination reduce eukaryotic initiation factor 2B ... is a fatal brain disorder caused by mutations in eukaryotic initiation factor 2B (eIF2B). eIF2B is essential for protein ... performed mutagenesis to introduce changes equivalent to 12 human CACH/VWM mutations in three subunits of the equivalent factor ...
Leukoencephalopathy with vanishing white matter: MedlinePlus Genetics
Mutations linked to leukoencephalopathy with vanishing white matter impair the function of the eukaryotic initiation factor 2B ... The eIF2 protein is called an initiation factor because it is involved in starting (initiating) protein synthesis. Proper ... or make it more difficult for the protein to attach to the initiation factor. ... Defective translation initiation causes vanishing of cerebral white matter. Trends Mol Med. 2006 Apr;12(4):159-66. doi: 10.1016 ...
MPD: Genes and genomic regions
Cell Biology: Less translational control, more memory | eLife
2011) The alpha subunit of eukaryotic initiation factor 2B (eIF2B) is required for eIF2-mediated translational suppression of ... 2012) Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism Adv Nutr 3:307-321. ... 2010) The mechanism of eukaryotic translation initiation and principles of its regulation Nat Rev Mol Cell Biol 11:113-127. ... Phosphorylation of the α-subunit of initiation factor 2 (eIF2) controls protein synthesis by a conserved mechanism. In metazoa ...
ELM - Detail for DOC PP2A B56 1
MIF4G domain-like, found in eukaryotic initiation factor eIF4G, translation initiation factor eIF-2b epsilon and nuclear cap- ... The N-terminal domain of eukaryotic translation initiation factor 3 subunit 12. The C-terminal domain of leukotriene A4 ... HEAT repeat domain, found in protein phosphatase 2a and initiation factor eIF4G. PHAT domain, found in the RNA-binding protein ... Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738) ELM data can be downloaded & distributed for ...
Results and submissions : REF 2021
Radiography - McMaster Experts
Ovarian Failure Related to Eukaryotic Initiation Factor 2B Mutations Academic Article * PRIMARY ANGIOSARCOMA OF THE BRAIN IN A ... Identifying factors likely to influence compliance with diagnostic imaging guideline recommendations for spine disorders among ... Prognostic Factors for Predicting Outcomes After Intramedullary Nailing of the Tibia Academic Article ... Changes in biomechanical risk factors for knee osteoarthritis and their association with 5-year clinically important ...
Neurofibromatosis (NF) Center - Research output
- Research Profiles at Washington University School of Medicine
Eukaryotic Initiation Factor-2B 26% * Medical Genetics 20% * Children with supratentorial midline pilocytic astrocytomas ... Estrogen hormone is an essential sex factor inhibiting inflammation and immune response in COVID-19. Li, F., Boon, A. C. M., ... An exploration of factors impacting implementation of a multisystem hospital-based violence intervention program. Mueller, K. L ... Examining the factor structure and discriminative utility of the Infant Behavior Questionnaire-Revised in infant siblings of ...
SMART: Pfam domain IF-2B
Initiation factor 2 binds to Met-tRNA, GTP and the small ribosomal subunit. The eukaryotic translation initiation factor EIF-2B ... This family includes initiation factor 2B alpha, beta and delta subunits from eukaryotes; related proteins from archaebacteria ... Many of these proteins were initially annotated as putative translation initiation factors despite the fact that there is no ... IF-2B. PFAM accession number:. PF01008. Interpro abstract (IPR000649):. ...
Blanc P
DeCS 2003 - Changed terms
DeCS 2003 - Changed terms
DeCS 2003 - Changed terms
DeCS 2003 - Changed terms
DeCS 2003 - Changed terms
DeCS 2003 - Changed terms
DeCS 2003 - Changed terms
DeCS 2003 - Changed terms
DeCS 2003 - Changed terms
DeCS 2003 - Changed terms
DeCS 2003 - Changed terms
DeCS 2003 - Changed terms
EIF2B2 gene mutation causing early onset vanishing white matter disease: a case report | Italian Journal of Pediatrics | Full...
Disease is caused by mutations in five genes encoding subunits of the translation initiation factor eIF2B. We know five ... Eukaryotic initiation factor 2B. WES:. Whole exome sequencing. EEG:. Electroencephalogram. MRI:. Magnetic Resonance imaging ... Disease is caused by mutations in five genes encoding subunits of the translation initiation factor eIF2B. We know five ... It is caused by mutations in the genes EIF2B1-5 that are involved in initiation and regulation of protein synthesis. VWMD is ...
Lilianna Solnica-Krezel - Research output
- Research Profiles at Washington University School of Medicine
Mouse Retina SAGE Library
Astrocytes are central in the pathomechanisms of vanishing white matter<...
... is a fatal leukodystrophy that is caused by mutations in genes encoding subunits of eukaryotic translation initiation factor 2B ... is a fatal leukodystrophy that is caused by mutations in genes encoding subunits of eukaryotic translation initiation factor 2B ... is a fatal leukodystrophy that is caused by mutations in genes encoding subunits of eukaryotic translation initiation factor 2B ... is a fatal leukodystrophy that is caused by mutations in genes encoding subunits of eukaryotic translation initiation factor 2B ...