Dibucaine number - Wikipedia
Typical measurement of dibucaine number in the United States yields values of 80 and above for wild type homozygotes (normal), ... measured 24,830 Dibucaine numbers over a period of four years in a European trial. Numbers below 30 (atypical homozygous) were ... Dibucaine numbers from 30 to 70 (atypical heterozygous) were found in 1.23% (n=306). On the basis of identification of the ... Dibucaine, also known as cinchocaine, is an amino amide local anesthetic. When administered to humans intravenously, it is ...
Dibucaine and Tetracaine Inhibit the Activation of Mitogen-activated Protein Kinase Mediated by L-type Calcium Channels in PC12...
Effects of Dibucaine and Tetracaine on MAP Kinase Phosphorylation Induced by Potassium Chloride To confirm that dibucaine and ... Effects of Dibucaine and Tetracaine on MAP Kinase Activation Induced by Potassium Chloride Dibucaine and tetracaine suppressed ... Although dibucaine and tetracaine inhibited the activation of MAP kinase induced by KCl and ionomycin, IC50values for dibucaine ... dibucaine, mitogen-activated protein kinases, potassium chloride, tetracaine, pc12 cells, calcium channels, l-type ...
Dibucaine Mitigates Spreading Depolarization in Human Neocortical Slices and Prevents Acute Dendritic Injury in the Ischemic...
Hence, dibucaine is a promising candidate to protect the brain from ischemic injury with an approach that does not rely on the ... Hence, dibucaine is a promising candidate to protect the brain from ischemic injury with an approach that does not rely on the ... Potent inhibition of anoxic depolarization by the sodium channel blocker dibucaine. * Authors: Douglas HA, Callaway JK, Sword J ... Dibucaine Mitigates Spreading Depolarization in Human Neocortical Slices and Prevents Acute Dendritic Injury in the Ischemic ...
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Our patients had both a decreased serum cholinesterase level and dibucaine number. The low dibucaine numbers confirm that both ... Determination of Dibucaine numbers. Can J. Biochem 1957; 35:339-46. 3. Barash PG, Cullen BF, Stoelting RK. Malignant ... This data led to the development of the utilization of a "dibucaine number" to represent the percentage of the enzyme reaction ... A fluoride number (analogous to dibucaine number) will demonstrate the percent inhibition of the enzyme to fluoride. When the ...
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Cholinesterase
Tests: Dibucaine Inhibition; Liver Panel. Suxamethonium Apnoea. Elsewhere On The Web. Wikipedia: Cholinesterase. MedicAlert ... This involves incubating the enzyme under standardised conditions with inhibitory agents such as dibucaine and fluoride and ... This involves incubating the enzyme under standardised conditions with inhibitory agents such as dibucaine and fluoride and ...
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Ten kinds of dibucaine salts were prepared. Effects of some counter ions on effective duration of surface anesthesia with ... Solvent affinity of dibucaine base, especially solubility in water and distribution ratio between chloroform and water were ... It seemed that entropy change of the interaction of dibucaine base and albumin was responsible for effective duration and half- ... It seemed that the change in solvent affinity was influenced by the change of hydrolytic constant of dibucaine salts. ...
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Inhibition of Bax-Induced Cytochrome c Release from Neural Cell and Brain Mitochondria by Dibucaine and Propranolol Brian M. ... Inhibition of Bax-Induced Cytochrome c Release from Neural Cell and Brain Mitochondria by Dibucaine and Propranolol Brian M. ... Inhibition of Bax-Induced Cytochrome c Release from Neural Cell and Brain Mitochondria by Dibucaine and Propranolol Brian M. ... Inhibition of Bax-Induced Cytochrome c Release from Neural Cell and Brain Mitochondria by Dibucaine and Propranolol Brian M. ...
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Where unusual dibucaine inhibition levels were observed, inhibition by 50 μM sodium fluoride was measured to distinguish ... Inhibition of activity by dibucaine was used to identify "atypical" (A) and fluoride-resistant (F) phenotypes. ... Identification of the structural mutation responsible for the dibucaine-resistant (atypical) variant form of human serum ...