The Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer is a free access database devoted to chromosomes, ... It was first published in 1983 as a book named "Catalog of Chromosome aberrations in Cancer" in the Journal of Cytogenetics and ... ISBN 0-8451-4248-8. Mitelman, Felix (1991). Catalog of chromosome aberrations in cancer (4th ed.). New York: Wiley-Liss. p. ... ISBN 0-471-56087-1. Mitelman, Felix (1994). Catalog of chromosome aberrations in cancer (5th ed.). New York: Wiley-Liss. p. ...
Patterns of chromosome abnormality: The key to cancer?. , January 24, 2012 , 0 responses ... A healthy genome is characterized by 23 pairs of chromosomes, and even a small change in this structure - such as an extra copy ... of a single chromosome - can lead to severe physical impairment. So it\s no surprise that when it comes to cancer, chromosomal ...
Furthermore, the RBE values for the induction of the two types of chromosome aberrations are similar to those establ … ... Chromosome aberration frequencies were determined by scoring fragments and translocations using premature chromosome ... Comparison of RBE values of high-LET α-particles for the induction of DNA-DSBs, chromosome aberrations and cell reproductive ... Furthermore, the RBE values for the induction of the two types of chromosome aberrations are similar to those established for ...
Mitelman, F. 1994: Catalog of chromosome aberrations in cancer, Fifth edition Chromosomes 1-12 Chromosomes 13-22, X, Y Mitelman ... Mitelman, F. 1991: Catalog of chromosome aberrations in cancer fourth edition chromosomes 1 12 chromosomes 13 22 x y references ... F Catalog of chromosome aberrations in cancer, Fifth edition: Chromosomes 1-12 (Part 1) Chromosomes 13-22, X, Y (Part 2) xxix+ ... F Catalog Of Chromosome Aberrations in Cancer, Fourth Edition; Chromosomes 1-12; Chromosomes 13-22, X, Y, References Xxxiv+998p ...
Gain of chromosome 1, the aberration most often seen in VIN III (67%), was not seen in HPV-positive or -negative VSCCs (0%). ... The most common chromosome aberration detected by high-resolution comparative genomic hybridization in vulvar intraepithelial ...
Herbert, Anthony (1982) Sister chromatid exchange and chromosome aberrations in human lymphocytes vs point-mutational damage in ... Sister chromatid exchange and chromosome aberrations in human lymphocytes vs point-mutational damage in bacteria : a study ... Sister chromatid exchange and chromosome aberrations in human lymphocytes vs point-mutational damage in bacteria : a study ... Sister chromatid exchange and chromosome aberrations in human lymphocytes vs point-mutational damage in bacteria : a study ...
Genotoxicity Testing of Neem Plant (Azadirachta indica A. Juss.) Using the Allium cepa Chromosome Aberration Assay. Journal of ... Genotoxicity Testing of Neem Plant (Azadirachta indica A. Juss.) Using the Allium cepa Chromosome Aberration Assay table, th, ...
... ... dose-response relationship by the method of maximum-likelihood and estimating a dose from the number of aberrations observed ...
Aberrations involving the number 5 chromosomes were identified using mBAND. Exchanges involving aberrant chromosomes 5 were ... Characterisation and transmissibility of α-particle-induced chromosome aberrations. J. Tawn1, C. Whitehouse2 and H. Thierens3 ... In recent years, in vitro studies have highlighted the complexity of chromosome aberrations induced by α-irradiation. Moreover ... the relationship between chromosome aberration frequencies in blood lymphocytes and dose is more difficult to establish. ...
... next-generation sequencing and arrays enable cytogenomic analysis of chromosome aberrations for constitutional and cancer ... Understanding chromosome aberrations through cytogenetic analysis is an integral part of current genomic medicine, playing a ... Illumina offers high-quality microarrays designed to detect chromosome aberrations and provide accurate, reliable cytogenomic ... Cytogenomic microarrays offer a simple, reliable method for assessing chromosomal aberrations at a higher resolution. ...
Kromosoomide ebanormaalne struktuur või nende arvu muutus rakus. Näiteks kromosoomsed puudujäägid (deletsioonid), duplikatsioonid, inversioonid, translokatsioonid, aneuploidsus, polüploidsus jt.. ...
It was long believed that there were 48 chromosomes in total, but no one was sure because it was difficult to obtain good ... Albert Levan, a researcher at Lund University, was the first to establish how many chromosomes there are in the human genome. ...
DNA and Chromosome Aberrations Branch. This branch administers extramural grants for studies in cancer genetics and epigenetics ...
The information in the Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer relates cytogenetic changes and ... The Clinical Associations Searcher searches studies pertaining to clinical associations of cytogenetic aberrations and/or gene ...
The nature of structural X chromosome aberrations in Turners syndrome as revealed by quinacrine mustard fluorescence analysis ... DNA CONTENT AND AREA OF SEX CHROMATIN IN SUBJECTS WITH STRUCTURAL AND NUMERICAL ABERRATIONS OF THE X CHROMOSOME ... The nature of structural X chromosome aberrations in Turners syndrome as revealed by quinacrine mustard fluorescence analysis ... Identification of the abnormal B group chromosome in the "cri du chat" syndrome by QM-fluorescence ...
Genes Chromosomes Cancer 58: 607-611, 2019.. Mitelman F, Johansson B, Mertens F, Schyman T, Mandahl N. Cancer chromosome ... The Database of Chromosome Aberrations and Gene Fusions in Cancer, established in 1980, is an attempt to register ... the role chromosome aberrations play in the formation of fusion genes, and the mechanisms by which gene fusions exert their ... Genes Chromosomes Cancer 55:291-310, 2016.. Mertens F, Johansson B, Fioretos T, Mitelman F. The emerging complexity of gene ...
Genes Chromosomes Cancer 58: 607-611, 2019.. Mitelman F, Johansson B, Mertens F, Schyman T, Mandahl N. Cancer chromosome ... The Database of Chromosome Aberrations and Gene Fusions in Cancer, established in 1980, is an attempt to register ... the role chromosome aberrations play in the formation of fusion genes, and the mechanisms by which gene fusions exert their ... Genes Chromosomes Cancer 55:291-310, 2016.. Mertens F, Johansson B, Fioretos T, Mitelman F. The emerging complexity of gene ...
These results strongly suggest that NS is mainly caused by structural aberrations in the nucleus during interphase of the cell ... Since nuclear swelling (NS hereafter) has been frequently observed in chromosomal aberration (CA hereafter) tests (in vitro), ... Table 2 Clastogens induced chromosome aberrations and nuclear swelling in CHL cells. Full size table. ... Takeshita, K., Ogawa, H.I. & Maeda, T. Structural chromosome aberrations cause swelling of the nucleus. Genes and Environ 38, ...
... but that they were associated with either chromosome aberrations or normal chromosome profiles. Multiple imprinted methylation ... Both Epimutations and Chromosome Aberrations Affect Multiple Imprinted Loci in Aggressive Wilms Tumors. Authors: L. Pignata, O ... Both Epimutations and Chromosome Aberrations Affect Multiple Imprinted Loci in Aggressive Wilms Tumors ... Link: Both Epimutations and Chromosome Aberrations Affect Multiple Imprinted Loci in Aggressive Wilms Tumors ...
A proposed system for scoring structural aberrations detected by chromosome painting. J. D. Tucker, W. F. Morgan, A. A. Awa, M ... The advent of chromosome painting has brought the realization that structural aberrations can be far more complicated than ... A proposed system for scoring structural aberrations detected by chromosome painting. / Tucker, J. D.; Morgan, W. F.; Awa, A. A ... A proposed system for scoring structural aberrations detected by chromosome painting. Cytogenetics and Cell Genetics. 1995;68(3 ...
Cells containing aberrations involving painted chromosomes (FISH aberrations) were further classified according to cell ... to paint chromosomes 1, 3 and 5. The whole genome was analyzed for unstable aberrations to derive aberration frequencies and ... The Characterization and Transmissibility of Chromosome Aberrations Induced in Peripheral Blood Lymphocytes by In Vitro α- ... The Characterization and Transmissibility of Chromosome Aberrations Induced in Peripheral Blood Lymphocytes by In Vitro α- ...
Associated defects and complications - Generally unknown; potential chromosome aberrations. * Clinical considerations: There ... Studies have demonstrated less-than-normal numbers of chromosomes and damage to the structure of chromosomes in the sperm of ...
DNA cytometry and chromosome 9 aberrations by fluorescence in situ hybridization of irrigation specimens from bladder cancer ... DNA cytometry and chromosome 9 aberrations by fluorescence in situ hybridization of irrigation specimens from bladder cancer ... DNA cytometry and chromosome 9 aberrations by fluorescence in situ hybridization of irrigation specimens from bladder cancer ... DNA cytometry and chromosome 9 aberrations by fluorescence in situ hybridization of irrigation specimens from bladder cancer ...
SKY and FISH analysis of radiation-induced chromosome aberrations: A comparison of whole and partial genome analysis ... SKY and FISH analysis of radiation-induced chromosome aberrations: A comparison of whole and partial genome analysis. Mutation ...
... in humans two chromosomes fused to form chromosome 2. Aberrations[edit]. In Down syndrome, there are three copies of chromosome ... Human chromosomes[edit]. Chromosomes in humans can be divided into two types: autosomes (body chromosome(s)) and allosome (sex ... Chromosome numbers in other organisms Species. Large. chromosomes. Intermediate. chromosomes. Microchromosomes Trypanosoma ... Chromosomes can also be fused artificially. For example, the 16 chromosomes of yeast have been fused into one giant chromosome ...
"Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer". cgap.nci.nih.gov. Retrieved 2018-11-27. Nathanson, ... Fikes, Bradley J. (9 February 2017). "Cancer genes hide outside chromosomes". sandiegouniontribune.com. Retrieved 2019-01-31. " ...