Calnexin (CNX) is a 67kDa integral protein (that appears variously as a 90kDa, 80kDa, or 75kDa band on western blotting ... Calnexin at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Benyair R, Ron E, Lederkremer GZ (2011). ... Calnexin is a chaperone, characterized by assisting protein folding and quality control, ensuring that only properly folded and ... Calnexin associates with the protein folding enzyme ERp57 to catalyze glycoprotein specific disulfide bond formation and also ...

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Ca2+ regulates erp57-calnexin complex formation. / Tanikawa, Yuya; Kanemura, Shingo; Ito, Dai et al. In: Molecules, Vol. 26, No ... Ca2+ regulates erp57-calnexin complex formation. Yuya Tanikawa, Shingo Kanemura, Dai Ito, Yuxi Lin, Motonori Matsusaki, Kimiko ... Dive into the research topics of Ca2+ regulates erp57-calnexin complex formation. Together they form a unique fingerprint. ... Here, we present mechanisms by which Ca2+ regulates the formation of the ERp57-calnexin complex. Biochemical and isothermal ...

Here we show that HPV16 E5 down-regulates HLA-I surface expression in calnexin-containing but not in calnexin-deficient cells. ... Besides, we demonstrate that E5 forms a ternary complex with calnexin and the heavy chain of HLA-I, which is mediated by the ... Immunoprecipitation experiments reveal that calnexin and HPV16E5 can be co-precipitated and that this association depends on ... in which the first putative transmembrane helix had been disrupted was used for the transfections calnexin-E5 co-precipitation ...

Links to domain combinations containing the P-domain of calnexin/calreticulin superfamily in all genomes. Links for both groups ... Click on a genome below to view all domain combinations containing a P-domain of calnexin/calreticulin domain in that genome. ... Domain combinations for P-domain of calnexin/calreticulin superfamily in groups of genomes. Domain combinations in groups of ...

... calnexin, an endoplasmic reticular (ER) calcium-binding protein gene, is expressed in PLL neuromasts. Knockdown of calnexin ... These results suggest that calnexin is essential for neuromast formation during lateral line development in the zebrafish. ... calnexin morphants. Finally, we discovered that the reduced PLLP is associated with a reduction in cell proliferation and ... zebrafish, calnexin, lateral line, neuromast, ER stress. Full text in web format is not available for this article. Please ...

... membrane protein with sequence similarity to calnexin and calreticulin and functions as a constituent of the ER quality control ... Saccharomyces cerevisiae CNE1 encodes an endoplasmic reticulum (ER) membrane protein with sequence similarity to calnexin and ... Saccharomyces cerevisiae CNE1 encodes an endoplasmic reticulum (ER) membrane protein with sequence similarity to calnexin and ...

Frenkel, Z., Shenkman, M., Kondratyev, M., & Lederkremer, G. Z. (2004). Separate Roles and Different Routing of Calnexin and ... Frenkel, Z, Shenkman, M, Kondratyev, M & Lederkremer, GZ 2004, Separate Roles and Different Routing of Calnexin and ERp57 in ... However, H2b, which will exit to the Golgi, dissociated from calnexin and remained bound for a longer period to ERp57, whereas ... However, H2b, which will exit to the Golgi, dissociated from calnexin and remained bound for a longer period to ERp57, whereas ...

Cited in 1 publications. View Rabbit Polyclonal anti-SEC22B Antibody - Azide and BSA Free (NB100-91277). Validated Applications: WB, IHC. Validated Species: Human, Mouse, Rat. Sample size available.

As shown in Figure 4(a), the cytoplasmic vacuoles induced by 125I seeds radiation colocalized with ER detected by Calnexin ... The primary antibodies against Akt, p-Akt (Thr308), Calnexin, and p-Akt (Ser473) were purchased from CST (Cell Signaling ... To further investigate the origin of vacuoles, immunofluorescence staining with anti-TIM23 and anti-Calnexin antibody was ... a) Immunofluorescence images stained with anti-Calnexin and anti-TIM23 antibody. Cytoplasmic vacuoles were denoted by white ...

Calnexin, calreticulin, and CypA are also involved; (4) Genome replication. HSP90, some members of HSP40 co-chaperones, TRiC/ ...

CANX: Calnexin; RTN4: Reticulon-4; MFN1: Mitofusin-1; OSBPL8: Oxysterol binding protein like 8; ABHD16A: Alpha/beta hydrolase ... Calnexin, ER), and supernatant containing cytosol (GAPDH, cytosol). (F) The 20,000× g pellet was solubilized and probed with ... Calnexin, calreticulin. Cytosol = GAPDH. Tom20, COXIV = mitochondria. (C) Top 50 protein candidates sorted by highest LFQ ...

Calnexin and Creb served as controls for membrane and nuclear proteins, respectively. (E) Total RNA was extracted from each ... Calnexin was used as an invariant control for membrane protein and was detected using a commercially available polyclonal ... and anti-calnexin primary antibodies were visualized using peroxidase-conjugated, affinity-purified, light-chain specific, goat ...

Apopro-MPO reversibly binds to chaperone proteins, calreticulin and calnexin, during protein maturation. This results in the ...

... the marker calnexin is commonly used. Rab proteins are specific markers of the endocytic route. Different proteins mark ...

Anti-Rab27a mouse mAb 4B12 (17), affinity-purified anti-Rab27b rabbit polyclonal Ab S086 (see below), anti-calnexin rabbit ... Anti-calnexin Ab recognizing a ubiquitous endoplasmic reticulum-membrane protein (ER-membrane protein) was used as a loading ... Anti-calnexin Ab recognizing a ubiquitous ER-membrane protein was used as a loading control. ...

Molecular Characterization and Identification of Calnexin 1 As a Radiation Biomarker from Tradescantia BNL4430 by Hye-Jeong Ha ... Calnexin (CNX) is an integral membrane protein that functions as a chaperone in the endoplasmic reticulum for the correct ... Calnexin (CNX) is an integral membrane protein that functions as a chaperone in the endoplasmic reticulum for the correct ... in which the Calnexin-1 gene was highly upregulated at 50 mGy treatment. TrCNX1 encodes a 61.4 kDa protein with conserved ...

Oda Y, Hosokawa N, Wada I, Nagata K . EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin. Science ... Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle. Science 2003; 299: 1397-1400. ...

... calnexin and albumin; C: Nanoparticle tracking analysis (NTA) plots for the size distribution and concentration of the isolated ...

Competition for Calnexin Binding Regulates Secretion and Turnover of Misfolded GPI-Anchored Proteins ...

Age-related decline in expression of calnexin Choi BH, Kim JS. *KMID: 1123772 ...

... calnexin (CANX) was not detected (Figure 4A and B). ...

A selective ER-phagy exerts procollagen quality control via a Calnexin-FAM134B complex.. Authors - Alison Forrester. View ...

UO126 was from Calbiochem; flavopiridol and anti-calnexin antibody was from Enzo Life Science (Farmingdale, NY); active CDK1- ... MEK1 as a cytoplasmic marker and calnexin as an ER marker, showing a separation of the membranes. As expected, in the control ...

Monitoring of S protein maturation in the endoplasmic reticulum by calnexin is important for the infectivity of severe acute ...

... and calnexin. Patricia Camacho Department of Neurosciences, University of Virginia, Charlottesville, VA, USA Luminal Control of ...

... oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin interacts transiently with ...

Role for N-glycans and calnexin-calreticulin chaperones in SARS-CoV-2 Spike maturation and viral infectivity. Sci Adv. 2022 09 ...

Clathrin, dynamin, calnexin, α-tubulin and Histone H3 were used as loading and purity controls for the NN and Nuc fractions, ... associated protein calnexin, were used to demonstrate nuclear fraction (Nuc) purity from other membrane-bound proteins and ER ...