Aminopropionitrile, also known as β-aminopropionitrile (BAPN), is an organic compound with both amine and nitrile functional ... Beta-amino-propionitrile (BAPN) found in lathyrus odoratus (common garden sweet pea) is thought to be responsible for ... Aminopropionitrile is prepared by the reaction of ammonia with acrylonitrile. Kashin-Beck disease Lysyl oxidase Marfan syndrome ... "Aminopropionitrile - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 25 March 2005. ...
Wound contraction is a clinically important biological process because it frequently results in contractures, strictures, and stenosis. If Collagen synthesis could be altered to minimize the contracture, then the outcome could be improved. Lathyrism produces poorly cross-linked Collagen in healing anastomosis, keeping a larger portion of the synthesized Collagen soluble. Ultimately, the amount of contracting Collagen is reduced, lowering the bulk and lessening the contracture. The aim of this study was to observe the effects of a lathyrogen, beta-aminoproplonitrile (BAPN), on the healing of colonic anastomosis. Thirty rats were divided into three groups. Colostomy and anastomosis were performed on all rats. Intraperitoneal saline solution (control) and either intraperitoneal (ip) or oral (po) BAPN were administered. The rats were killed I week later. Anastomotic healing was assessed by bursting pressure and the hydroxyproline content of the anastomotic tissues. Granulation tissue thickness ...
β-Aminopropionitrile-Induced Reduction in Enzymatic Crosslinking Causes In Vitro Changes in Collagen Morphology and Molecular ... a step which can be disrupted using β-aminopropionitrile (BAPN). Murine in vivo studies have confirmed effects of BAPN on ...
3-Aminopropionitrile 151-18-8. Inquire. 1,2-Epoxycyclododecane 286-99-7. Inquire. ...
8. Inhibition of Lysyl Oxidase with β-aminopropionitrile Improves Venous Adaptation after Arteriovenous Fistula Creation. ...
For this function, we have examined the effect of -aminopropionitrile (BAPN), a particular and irreversible inhibitor of LOX ... In obese rats, the inhibition of LOX activity through -aminopropionitrile (BAPN, a particular inhibitor of LOX activity) ...
Mechanical and matrix effects of short and long-duration exposure to beta-aminopropionitrile in elastase-induced model ...
... β-aminopropionitrile (BAPN) for six weeks. BAPN is a chemical lathyrogen known to interfere with the formation of elastin and ...
... beta-aminopropionitrile]] (BAPN), which inhibits the copper-containing enzyme [[lysyl oxidase]], responsible for cross-linking ... caused by the toxin beta-amino-propionitrile (BAPN) because it affects the bones and connecting tissues, instead the nervous ...
Integrative cartilage repair: inhibition by beta-aminopropionitrile. J Orthop Res. 1999 Nov; 17(6):850-7. Ahsan T, Lottman LM, ... Treatment of cartilage with beta-aminopropionitrile accelerates subsequent collagen maturation and modulates integrative repair ... modulation of balance between proteoglycan and collagen network in vitro with beta-aminopropionitrile. Osteoarthritis Cartilage ...
... who induced arterial wall weakening in rats by ingestion of three-beta-aminopropionitrile, a poisonous agent extracted from the ...
5E). Use of the LOX inhibitor, β-aminopropionitrile (BAPN), demonstrated LOX-substrate specificity, whereas recombinant active ...
Native type II collage, isolated from sternal cartilage of chicks rendered lathyritic by administration of 8-aminopropionitrile ...
InChI=1S/C16H14O5/c1-11(17)20-13-8-4-3-7-12(13)16(18)21-15-10-6-5-9-14(15)19-2/h3-10H,1- ...
Mathieu P, Villemot JP, Stoltz JF, Scheck F, Garnier LF (June 1996). "[Antiaggregant effect and tolerance of calcium carbasalate administrated immediately after aorto-coronary bypass. Results of a double-blind versus placebo study]". Pathologie-Biologie. 44 (6): 571-80. PMID 8977914 ...
Aminopropionitrile - Preferred Concept UI. M0000960. Scope note. Reagent used as an intermediate in the manufacture of beta- ...
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Aminopropionitrile. Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.. ... 2-Oxoglutarate 5-DioxygenaseProlineAminopropionitrileDecorinCell AdhesionTransforming Growth Factor betaCollagen Type XIII ... 2-Oxoglutarate 5-DioxygenaseProlineAminopropionitrileDecorinTransforming Growth Factor betaCollagen Type XIIIIntegrin ...
Herchenhan, A., Uhlenbrock, F. K., Eliasson, P., Weis, M., Eyre, D., Kadler, K. E., Magnusson, S. P. & Kjaer, M., 26 Jun 2015, In: Journal of Biological Chemistry. 290, 26, p. 16440-50 11 p.. Research output: Contribution to journal › Journal article › Research › peer-review ...
Khalkhali-Ellis, Z., Seftor, E. A., Nieva, D. R. C., Handa, R. J., Price, R. H., Kirschmann, D. A., Baragi, V. M., Sharma, R. V., Bhalla, R. C., Moore, T. L. & Hendrix, M. J. C., 2000, In: Journal of Rheumatology. 27, 7, p. 1622-1631 10 p.. Research output: Contribution to journal › Article › peer-review ...
Sweet peas contain a poison called 3-aminopropionitrile. This is not a protein poison, and the toxicity is not inactivated by ...
The enzyme was fully inhibited in vivo by beta-aminopropionitrile.... journal_title:International journal of experimental ...
METHODS: ß-aminopropionitrile monofumarate was administrated in mice to induce TAD. NE deficiency mice, pharmacological ... RESULTS: NE aortic gene expression and plasma activity was significantly increased during ß-aminopropionitrile monofumarate- ... NE deficiency prevents ß-aminopropionitrile monofumarate-induced TAD onset/development, and GW311616A administration ...
Rats administered beta-aminopropionitrile developed aneurysmal-like bone cysts in the mandible. These formulas are mostly water ...
Fenproporex (d,l-3-[(α-methylphenethyl)amino]propionitrile) and any salt thereof. *. 22 ...
Side effects of phenylbutazone are similar to that of other NSAIDs. Overdose or prolonged use can cause gastrointestinal ulcers, blood dyscrasia, kidney damage, oral lesions, and internal hemorrhage, especially pronounced in young, ill, or stressed horses. Effects of gastrointestinal damage include edema of the legs and belly secondary to leakage of blood proteins into the intestines, resulting in decreased appetite, excessive thirst, weight loss, weakness, and in advanced stages, kidney failure and death. Phenylbutazone should not be used in combination with blood thinners (e.g., Coumadin), as it amplifies the anticoagulant effects of these drugs; with other NSAIDs (all NSAIDs are additive); or in horses with known kidney or liver problems. Periodic blood tests are recommended when using phenylbutazone as Agranulocytosis can occur. Periodically testing the blood may catch this issue before it is too late. Phenylbutazone should be used cautiously in pregnant or nursing mares, as it may be toxic ...
This flowering plant contains a toxin called aminopropionitrile, which can cause the following aftermath in your dogs: ...
Aminopropionitrile. *Amygdalin. *Carbonyl Cyanide m-Chlorophenyl Hydrazone. *Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone ...
Three weeks later, angiotensin II (Ang II) and β-aminopropionitrile (BAPN), a lysyl oxidase inhibitor, were administered with ...