Acinar cell carcinoma of the pancreas, also acinar cell carcinoma, is a rare malignant exocrine tumour of the pancreas. It ... Feb 2010). "[A case of acinar cell carcinoma of pancreas, manifested by subcutaneous nodule as initial clinical symptom]". ... Klimstra, DS.; Heffess, CS.; Oertel, JE.; Rosai, J. (Sep 1992). "Acinar cell carcinoma of the pancreas. A clinicopathologic ... Light microscopy of an acinar cell carcinoma biopsy typically shows granular appearance. Immunohistochemistry is usually ...

Comparative profiling of single-cell transcriptome reveals heterogeneity of tumor microenvironment between solid and acinar ... Immunologically, solid LUADs are characterized by a predominance of exhausted T cells and immunosuppressive myeloid cells, ... Discrepancies in stromal cell function, evidenced by varying degrees of stromal remodeling and fibrosis, may also contribute to ... Remarkably, tumor cells from solid LUADs upregulate energy and substance metabolic activities, particularly the folate-mediated ...

Cell Type. pancreatic acinar cell Cellular Component. nucleus nucleolus chromatin rough endoplasmic reticulum ribosome nuclear ... from: Don W. Fawcett M.D The Cell 2nd edition, W.B. Saunders Chapter 4 (Nucleus) Link. ASCB BioEDUCATE Program ... Image extracted from .pdf file of The Cell Data Qualifiers. processed data ... Don W. Fawcett (2011) CIL:10976, Myotis lucifugus, pancreatic acinar cell. CIL. Dataset. https://doi.org/doi:10.7295/W9CIL10976 ...

Cell Culture. The 293H cells were obtained from Invitrogen/Life Technologies, and are documented by Gibcos Master Cell Bank. ... Cell Viability and Growth Inhibition Assays. Cells were seeded at 3,000 cells per well (GTL16.903.R1 drug treatments in ... 14 mixed acinar/neuroendocrine, 6 mixed acinar/ductal, 2 mixed acinar/neuroendocrine/ductal, and 6 samples with incomplete ... Cell Signaling Technology; #9154), total MEK1/2 (Cell Signaling Technology; #9126), phospho-ERK1/2 (Thr202/Tyr204; Cell ...

miR-352 participates in the regulation of trypsinogen activation in pancreatic acinar cells by influencing the function of ... The results of the verification experiment showed that in the TLC-S-treated AR42J (pancreatic cell line) cells, miR-352 ... The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed ... In the miR-352 mimic-transfected cells, miR-352 expression increased, expression levels of LAMP2 and CTSL1 were significantly ...

Cells lining the saclike dilatations known as acini of various glands or the lungs.. ...

Representative examples include the acinar cell carcinoma of the pancreas and the acinar adenocarcinoma of the prostate gland. ... A malignant glandular epithelial neoplasm consisting of secretory cells forming acinar patterns. ... Acinar Carcinoma; Acinar Carcinomas; Acinar Cell Adenocarcinoma; Acinar Cell Adenocarcinomas; Acinar Cell Carcinoma; Acinar ... Acinar Cell; Carcinoma, Acinic Cell; Carcinomas, Acinar; Carcinomas, Acinar Cell; Carcinomas, Acinic Cell; Tumor, Acinic Cell; ...

Salem, M. S., S. S. Hassan, T. McGarvey, and R. Rachakatla, Histological changes in the rat acinar cells of the submandibular ... Histological changes in the rat acinar cells of the submandibular gland consequent to oxybutynin and the reversible effect of ... Histological changes in the rat acinar cells of the submandibular gland consequent to oxybutynin and the reversible effect of ...

Cholinergic Intrapancreatic Neurons Induce Ca2+ Signaling and Early-Response Gene Expression in Pancreatic Acinar Cells. ... Cholinergic Intrapancreatic Neurons Induce Ca2+ Signaling and Early-Response Gene Expression in Pancreatic Acinar Cells. ...

Overlap of CD44 expression between prostatic small cell carcinoma and acinar adenocarcinoma. Human pathology. 2015 Apr 1;46(4): ... Overlap of CD44 expression between prostatic small cell carcinoma and acinar adenocarcinoma. / Wang, Chung Chieh; De Marzo, ... Overlap of CD44 expression between prostatic small cell carcinoma and acinar adenocarcinoma. In: Human pathology. 2015 ; Vol. ... keywords = "Acinar adenocarcinoma, CD44, Immunohistochemistry, Prostate cancer, Small cell carcinoma",. author = "Wang, {Chung ...

... as compared to pcDNA cells and the wild-type cells. In conclusion, cerulein induces cytokine expression and apoptotic cell ... as compared to pcDNA cells and the wild-type cells. In conclusion, cerulein induces cytokine expression and apoptotic cell ... as compared to pcDNA cells and the wild-type cells. In conclusion, cerulein induces cytokine expression and apoptotic cell ... as compared to pcDNA cells and the wild-type cells. In conclusion, cerulein induces cytokine expression and apoptotic cell ...

Keating C, Orchard I. Dopamine induces hyperpolarization of locust salivary gland acinar cells via D1-like receptors. Journal ... Keating, C & Orchard, I 2001, Dopamine induces hyperpolarization of locust salivary gland acinar cells via D1-like receptors. ... Dopamine induces hyperpolarization of locust salivary gland acinar cells via D1-like receptors. / Keating, Christopher; Orchard ... Application of dopamine induced a reversible, dose-dependent hyperpolarization of the acinar cells, with an EC50 of 0.1 μM ...

Chao, K. C., Chao, K. F., Chuang, C. C., & Liu, S. H. (2006). Blockade of interleukin 6 accelerates acinar cell apoptosis and ... This study examined the effect of neutralizing antibody against IL-6 on the induction of pancreatic acinar cell apoptosis and ... Application of IL-6 neutralizing antibody caused the induction of apoptosis in the pancreatic acinar cells of mice with acute ... This study examined the effect of neutralizing antibody against IL-6 on the induction of pancreatic acinar cell apoptosis and ...

PACC is an epithelial neoplasm with evidence of acinar differentiation. Patients with acinar cell carcinoma have a better ... Clinical features and CT/MRI findings of pancreatic acinar cell carcinoma. Int J Clin Exp Med. 2015. 8 (9):14846-54. [QxMD ... Pancreatic acinar cell carcinomas (PACCs) constitute approximately 1% of exocrine pancreatic tumors. ... Many pancreatic tumors can become calcified, including adenocarcinoma (rare), islet cell tumor, microcystic adenoma-sunburst ...

A Betacellulin Mutant Promotes Differentiation of Pancreatic Acinar AR42J Cells into Insulin-Producing Cells with Low Affinity ... BTC promotes the differentiation of pancreatic acinar-derived AR42J cells into insulin-producing cells. It independently and ... A Betacellulin Mutant Promotes Differentiation of Pancreatic Acinar AR42J Cells into Insulin-Producing Cells with Low Affinity ... A Betacellulin Mutant Promotes Differentiation of Pancreatic Acinar AR42J Cells into Insulin-Producing Cells with Low Affinity ...

We now report that in mouse pancreatic acinar cells, cholecystokinin, but not acetylcholine, evokes rapid and transient ... pharmacological studies alone have implicated these molecules as intracellular second messengers for specific cell surface ... Role of NAADP and cADPR in the induction and maintenance of agonist-evoked Ca2+ spiking in mouse pancreatic acinar cells. ... Role of NAADP and cADPR in the induction and maintenance of agonist-evoked Ca2+ spiking in mouse pancreatic acinar cells. ...

Acinic cell carcinoma (ACC) is a low-grade malignant salivary neoplasm that constitutes approximately 17% of primary salivary ... Carcinoma, Acinar Cell / pathology* * Carcinoma, Acinar Cell / therapy * Humans * Salivary Gland Neoplasms / pathology* ... Acinic cell carcinoma of the salivary glands: a literature review Hematol Oncol Stem Cell Ther. 2009;2(1):259-64. doi: 10.1016/ ... Acinic cell carcinoma (ACC) is a low-grade malignant salivary neoplasm that constitutes approximately 17% of primary salivary ...

A mathematical model of fluid secretion from a parotid acinar cell.﻽. Gin E, Crampin EJ, Brown DA, Shuttleworth TJ, Yule DI, ... Ultrastructure and cell-cell coupling of cardiac myocytes differentiating in embryonic stem cell cultures.﻽. Westfall MV, Pasyk ... In acinar cells the distribution of these receptors is tightly localized to an area associated with the actin cytoskeleton in ... A Model of [Formula: see text] Dynamics in an Accurate Reconstruction of Parotid Acinar Cells.﻽. Pages N, Vera-Sigüenza E, ...

Pancreas - Acinar cell hyperplasia. Strain. CBA. Tumor Inducing Agent(s). Radiation : radiofrequency (RF) radiation • ionizing ... Model DetailsPancreas - Acinar cell hyperplasia. Model Name. ... Pancreas - Acinar cell. Female. 10%. (5 of 50 mice) 81-83 weeks ...

Acinar cell carcinoma has been reported as the most common malignancy associated with PPP [3]. The pathophysiology of the ... Biopsy of the pancreatic and hepatic masses were positive for an acinar cell carcinoma. During initial treatment with ... Pancreatic Disease, Panniculitis, and Polyarthritis Syndrome: Initial Manifestation of Acinar Cell Carcinoma. ...

Regulation of acinar cell function in the pancreas. Curr Opin Gastroenterol. 2010;26:478-83. ... mechanisms activated by cholecystokinin-regulating synthesis and secretion of digestive enzymes in pancreatic acinar cells. ...

Exocrine Effects on Endocrine Cells: Protective Effects of Insulin on Acinar Cells During Pancreatitis. Jason Bruce. 2:20 p.m ... Assessing Acinar and Duct Cell Function: Gaps and Opportunities. Mark Lowe. 10:55 a.m. - 11:20 a.m.. Mechanisms and Biomarkers ... Exocrine Effects on Endocrine Cells: Lessons from Cystic Fibrosis-related Diabetes. John Englehardt. 1:55 p.m. - 2:20 p.m.. ...

... renal and transitional cell carcinomas were also positive. Knowledge of the expression patterns of HE4 in our survey is useful ... However, adenocarcinomas of the lung, and occasional breast, transitional cell and pancreatic carcinomas had moderate or high ... with weaker and focal staining of the acinar cells. Scattered cells in the anterior pituitary gland were strongly positive. ... Only one of 26 renal cell carcinomas, clear cell type, was positive, while five of 13 papillary renal cell carcinomas ...

Acinar cells of the lacrimal glands express thyroid-stimulating hormone (TSH) receptors. The TNF-alpha binds and results in ... In thyroid eye disease, the orbit is infiltrated by B and T cells and CD34+ fibrocytes from the bone marrow. These fibrocytes ... A subset of orbital fibroblasts in the orbit can differentiate into mature, lipid-accumulating cells or de novo adipogenesis. ... 2001/viewarticle/rethinking-approach-manage-fever-ed-children-sickle-cell-2023a1000o23. news Rethinking Approach to Manage ...

Loss of acinar cell VMP1 triggers spontaneous pancreatitis in mice. Title: Loss of acinar cell VMP1 triggers spontaneous ... Loss of acinar cell VMP1 triggers spontaneous pancreatitis in mice. Wang S, et al. Autophagy, 2022 Jul. PMID 34709991, Free PMC ... involved_in cell-cell adhesion ISO Inferred from Sequence Orthology. more info ... VMP1 prevents Ca2+ overload in endoplasmic reticulum and maintains naive T cell survival. Liu Y, et al. J Exp Med, 2023 Jun 5. ...

Acinar cell carcinoma *solid and papillary epithelial neoplasm *Pseudoaneurysm of the splenic artery from pancreatitis *Chronic ...

Fatal horse cases-pancreatic lesions (acinar cells), hematopoietic involvement with or without encephalitis. See Reference 27 ... Brain (M)(LV), liver (LV), kidney (LV), marrow (LV) and acinar cells of pancreas ...

In line with this, RBPJL is able to fully reconstitute transcriptional repression at Notch target genes in cells lacking RBPJ. ... RBPJL is specifically expressed in the exocrine pancreas, whereas it is mostly undetectable in pancreatic tumour cell lines. ... Together, RBPJL can act as an antagonist of RBPJ, which renders cells unresponsive to the activation of Notch. ... can bind to canonical RBPJ DNA elements and shows migration dynamics comparable to that of RBPJ in the nuclei of living cells. ...