*  Jallow Z et al. (2004), Specialized and redundant roles of TBP and a ve... - Xenbase Paper
The general transcription factor TATA-binding protein (TBP) is a key initiation factor involved in transcription by all three ... TBP2 may be a TBP replacement factor in oocytes, whereas in embryos both TBP and TBP2 are required even though they exhibit ... In addition, the related metazoan-specific TBP-like factor (TLF/TRF2) is essential for transcription of a distinct subset of ... In embryos, TBP2 protein is much less abundant than TBP, and moderate overexpression of TBP2 partially rescues an antisense ...
  http://www.xenbase.org/literature/article.do?method=display&articleId=3067
*  Mutations in the RNA Polymerase III Subunit Rpc11p That Decrease RNA 3′ Cleavage Activity Increase 3′-Terminal Oligo(U) Length...
Termination by RNA polymerase III (Pol III) produces RNAs whose 3′ oligo(U) termini are bound by La protein, a chaperone that ... The fission yeast TFIIB-related factor limits RNA polymerase III to a TATA-dependent pathway of TBP recruitment. Nucleic Acids ... The La protein. Annu. Rev. Biochem. 71:375-403. [PubMed]. 38. Yoo, C. J., and S. L. Wolin. 1997. The yeast La protein is ... Structure of a new nucleic-acid-binding motif in eukaryotic transcriptional elongation factor TFIIS. Nature 365:277-279. [ ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC543423/?lang=en-ca
*  TAF1 - Wikipedia
"The retinoblastoma-susceptibility gene product binds directly to the human TATA-binding protein-associated factor TAFII250". ... "The retinoblastoma-susceptibility gene product binds directly to the human TATA-binding protein-associated factor TAFII250". ... TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated ... TATA box binding protein (TBP)-associated factor, 250kDa". Sekiguchi T, Yoshida MC, Sekiguchi M, Nishimoto T (April 1987). " ...
  https://en.wikipedia.org/wiki/TAF1
*  TATA-binding protein - Wikipedia
The TATA-binding protein (TBP) is a general transcription factor that binds specifically to a DNA sequence called the TATA box ... "Transcription factor IIA derepresses TATA-binding protein (TBP)-associated factor inhibition of TBP-DNA binding". J. Biol. Chem ... Type 17 Interactive TBP Structure at massey.ac.nz PDB Molecule of the Month TATA-binding protein TATA-Box Binding Protein at ... this region binds to the TATA box and interacts with transcription factors and regulatory proteins . By contrast, the N- ...
  https://en.wikipedia.org/wiki/TATA-binding_protein
*  TERF2 - Wikipedia
"Human TATA-binding protein-related factor-2 (hTRF2) stably associates with hTFIIA in HeLa cells". Proc. Natl. Acad. Sci. U.S.A ... There are 4 domain categories on the TERF2 protein that allow it to bind to both other proteins in the shelterin protein ... Telomeric repeat-binding factor 2 is a protein that is present at telomeres throughout the cell cycle. It is also known as ... which is the binding site of TERF2 where it recruits client proteins. These client proteins also contain a TRFH binding motif, ...
  https://en.wikipedia.org/wiki/TERF2
*  GTF2A1 - Wikipedia
"Transcription factor IIA derepresses TATA-binding protein (TBP)-associated factor inhibition of TBP-DNA binding". The Journal ... "Transcription factor IIA derepresses TATA-binding protein (TBP)-associated factor inhibition of TBP-DNA binding". The Journal ... "An interplay between TATA box-binding protein and transcription factors IIE and IIA modulates DNA binding and transcription". ... GTF2A1 has been shown to interact with TATA binding protein and TBPL1. Transcription Factor II A Model organisms have been used ...
  https://en.wikipedia.org/wiki/GTF2A1
*  TBPL1 - Wikipedia
Chong JA, Moran MM, Teichmann M, Kaczmarek JS, Roeder R, Clapham DE (Apr 2005). "TATA-binding protein (TBP)-like factor (TLF) ... TATA box-binding protein-like protein 1 is a protein that in humans is encoded by the TBPL1 gene. Initiation of transcription ... TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated ... "TATA box-binding protein (TBP)-related factor 2 (TRF2), a third member of the TBP family". Proceedings of the National Academy ...
  https://en.wikipedia.org/wiki/TBPL1
*  GTF2F1 - Wikipedia
TATA binding protein, and Transcription Factor II B. Transcription factor II F GRCh38: Ensembl release 89: ENSG00000125651 - ... "Rb inhibits the intrinsic kinase activity of TATA-binding protein-associated factor TAFII250". Mol. Cell. Biol. 19 (1): 846-54 ... Fang SM, Burton ZF (May 1996). "RNA polymerase II-associated protein (RAP) 74 binds transcription factor (TF) IIB and blocks ... Fang SM, Burton ZF (1996). "RNA polymerase II-associated protein (RAP) 74 binds transcription factor (TF) IIB and blocks TFIIB- ...
  https://en.wikipedia.org/wiki/GTF2F1
*  The multicoloured world of promoter recognition complexes | The EMBO Journal
Crowley TE, Hoey T, Liu JK, Jan YN, Jan LY, Tjian R (1993) A new factor related to TATAbinding protein has highly restricted ... Mitsuzawa H, Seino H, Yamao F, Ishihama A (2001) Two WD repeat‐containing TATAbinding protein‐associated factors in fission ... Tora L (2002) A unified nomenclature for TATA box binding protein (TBP)‐associated factors (TAFs) involved in RNA polymerase II ... The shift from utilisation of a TATA‐containing promoter to a TATA‐less promoter of the protein translation initiation factor ...
  http://emboj.embopress.org/content/23/1/2
*  TAF9 - Wikipedia
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa, also known as TAF9, is a protein that in ... TATA binding protein, Transcription initiation protein SPT3 homolog, and Transformation/transcription domain-associated protein ... TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated ... TATA box binding protein (TBP)-associated factor, 32kDa". Evans SC, Foster CJ, El-Naggar AK, Lozano G (April 1999). "Mapping ...
  https://en.wikipedia.org/wiki/TAF9
*  TAF6 - Wikipedia
"Entrez Gene: TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa". Hsieh YJ, Kundu TK, Wang Z ... TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated ... and transactivation-defective mutants of human immunodeficiency virus type 1 Tat protein bind human TATA-binding protein in ... The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position ...
  https://en.wikipedia.org/wiki/TAF6
*  PAX5 - Wikipedia
... is an interaction motif for the retinoblastoma and TATA-binding proteins". Cancer Research. 59 (7 Suppl): 1716s-1724s; ... "Id helix-loop-helix proteins antagonize pax transcription factor activity by inhibiting DNA binding". Molecular and Cellular ... Paired box protein Pax-5 is a protein that in humans is encoded by the PAX5 gene. The PAX5 gene is a member of the paired box ( ... PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, ...
  https://en.wikipedia.org/wiki/PAX5
*  The TATAbinding protein regulates maternal mRNA degradation and differential zygotic transcription in zebrafish | The EMBO...
Chong JA, Moran MM, Teichmann M, Kaczmarek JS, Roeder R, Clapham DE (2005) TATAbinding protein (TBP)‐like factor (TLF) is a ... Persengiev SP, Zhu X, Dixit BL, Maston GA, Kittler EL, Green MR (2003) TRF3, a TATA‐box‐binding protein‐related factor, is ... A human TATA binding protein‐related protein with altered DNA binding specificity inhibits transcription from multiple ... Human TATAbinding protein‐related factor‐2 (hTRF2) stably associates with hTFIIA in HeLa cells. Proc Natl Acad Sci USA 96: ...
  http://emboj.embopress.org/content/26/17/3945
*  Selective factor 1 - Wikipedia
SL1 is composed of the TATA-binding protein and three TAF (TATA box-binding protein-associated factor) subunits (TAF1A, TAF1B, ... "Patent US5637686 - Tata-binding protein associated factor, nucleic acids - Google Patents". Google.com. Retrieved 2014-08-10. ... This binding is not due to polymerase I itself but to a transcription factor called upstream binding factor, UBF. SLI functions ... "The species-specific RNA polymerase I transcription factor SL-1 binds to upstream binding factor" (PDF). Molecular and Cellular ...
  https://en.wikipedia.org/wiki/Selective_factor_1
*  Retinoblastoma protein - Wikipedia
"The retinoblastoma-susceptibility gene product binds directly to the human TATA-binding protein-associated factor TAFII250". ... "Differential specificity for binding of retinoblastoma binding protein 2 to RB, p107, and TATA-binding protein". Mol. Cell. ... Rb binds and inhibits E2 promoter-binding-protein-dimerization partner (E2F-DP) dimers, which are transcription factors of the ... "Rb Inhibits the Intrinsic Kinase Activity of TATA-Binding Protein-Associated Factor TAFII250". Mol. Cell. Biol. 19 (1): 846-54 ...
  https://en.wikipedia.org/wiki/Retinoblastoma_protein
*  Retinoblastoma: Mutation of Rb-1 Protein
Amino Acid Sequence Two binding sites ( aa 389-580 & 614-892) bind the transcription factor and the transcription factor s ... is an interaction motif for the retinoblastoma and TATA-binding Proteins. Cancer Research. 59:1716s-1725s.. Lai, A., Marcellus ... The Rb-1 protein s effect is seen during the G1 phase proceeding the restriction point. During the G1 phase, Rb is bound to the ... The Rb gene is an important factor in this disease. Rb-1 is a tumor suppressor gene. It s found in all cells of the body and ...
  http://www.webclearinghouse.net/volume/3/KELLY-Retinoblas.php
*  Networks in Cell Biology | SpringerLink
A neurological disease caused by an expanded cag trinucleotide repeat in the tata-binding protein gene: a new polyglutamine ... Davidson, I. (2003). The genetics of tbp and tbp-related factors. Trends Biochem. Sci., 28(7):391-8.PubMedCrossRefGoogle ... complex protein formation or DNA-protein binding. Erom these interactions large-scale systems emerge as a mesh of relations: ... Sonnhammer, E.L. and Kahn, D. (1994). Modular arrangement of proteins as inferred from analysis of homology. Protein Sci., 3(3 ...
  https://link.springer.com/chapter/10.1007/978-0-387-47509-7_10
*  Splicing-transcription connectors - Biology Online
... as a TATA binding protein (TBP)-associated factor; that is, as a component of transcription factor TFIID (Bertolotti et al. ... One of these proteins, HPV-5 E2, interacts, via this RS domain-like region, with splicing factors, including SR proteins, and ... The human papillomavirus (HPV) E2 protein provides an example of a sequence-specific DNA binding protein that may also serve to ... Although nothing definitive is known regarding such hypothetical protein linkers, several proteins, or protein families, merit ...
  http://www.biology-online.org/articles/rna_polymerase_ii_integration/splicing-transcription_connectors.html
*  TAF5 - Wikipedia
"Entrez Gene: TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa". Tao Y, Guermah M, Martinez ... TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated ... and transactivation-defective mutants of human immunodeficiency virus type 1 Tat protein bind human TATA-binding protein in ... The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position ...
  https://en.wikipedia.org/wiki/TAF5
*  High affinity binding of proteins HMG1 and HMG2 to semicatenated DNA loops | BMC Molecular Biology | Full Text
... such as the sex-determination factor Sry and the Sox family of proteins. In vitro studies of interactions of HMG1/2 with DNA ... have shown that these proteins can bind to many unusual DNA structures, in particular to four-way junctions, with binding ... The binding constant of HMG1 to Form X is higher than 5 × 1012 M-1, and the half-life of the complex is longer than one hour in ... This suggests that, if similar structures exist in the cell nucleus, one of the functions of these proteins might be linked to ...
  https://bmcmolbiol.biomedcentral.com/articles/10.1186/1471-2199-1-1
*  Heterogeneous nuclear ribonucleoprotein D0B is a sequence-specificDNA-binding protein | Biochemical Journal
Co-precipitation of a complex formed in vivo between hnRNP D0B and the TATA-binding protein demonstrates that hnRNP D0B ... and single-stranded DNA sequences in a specific manner and functioning as a transcription factor. ... The intranuclear concentration of sequence-specific protein was estimated to be 250-400 nM, indicating that the protein binds ... Heterogeneous nuclear ribonucleoprotein D0B is a sequence-specificDNA-binding protein. Mate TOLNAY, Lyudmila A. VERESHCHAGINA, ...
  http://www.biochemj.org/content/338/2/417
*  IJMS | Free Full-Text | Tailoring the Models of Transcription | HTML
The understanding of promoter complexity and transcription factor structure offers an insight into the mechanisms of ... as well as transcription factors in order to examine their function. ... on some of the many applications of molecular cut-and-paste tools for the manipulation of promoters and transcription factors ... Transcription is the first step in protein expression and the major point of regulation of the components that determine the ...
  http://mdpi.com/1422-0067/14/4/7583/htm
*  Two distinct domains of Bicoid mediate its transcriptional downregulation by the Torso pathway | Development
Bicoid functions without its TATA-binding protein-associated factor interaction domains. Proc. Natl. Acad. Sci. USA 96, 4461- ... It is probable that the transcription factors binding in the proximity of the Bcd protein in these control regions might have ... 3B, lane 4). In contrast, a protein containing only the DNA-binding and the ST domains (HD/ST, Fig. 3A) was as potent as ΔQAC ( ... Several Gal4 fusion proteins containing the Gal4 DNA-binding domain and the Bcd domains were expressed in transgenic animals as ...
  http://dev.biologists.org/content/128/12/2281
*  TBP Gene - GeneCards | TBP Protein | TBP Antibody
Protein Coding), TATA-Box Binding Protein, including: function, proteins, disorders, pathways, orthologs, and expression. ... The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position ... The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition. ( ... Protein Symbol:. P20226-TBP_HUMAN. Recommended name:. TATA-box-binding protein Protein Accession:. P20226. Secondary Accessions ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=TBP
*  Transcription factor IIIB 50 kDa subunit - Wikipedia
2003). "The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box ... Transcription factor IIIB 50 kDa subunit (TFIIIB50) also known as b-related factor 2 (BRF-2) is a protein that in humans is ... to the TATA box of polymerase III small nuclear RNA gene promoters through its interaction with the TATA-binding protein. ... recruited to the TATA-box of polymerase III small nuclear RNA gene promoters through its interaction with TATA-binding protein ...
  https://en.wikipedia.org/wiki/Transcription_factor_IIIB_50_kDa_subunit