*  Recombinant Human Bone Morphogenetic Protein 2 in Augmentation Procedures: Case Reports
... Jaques Luiz, DDS, MSc/Luis Eduardo ... An alternative is to use recombinant human bone morphogenetic protein 2 (rhBMP-2), which is able to support bone regeneration ... Several techniques have been proposed for augmentation of sites with insufficient bone volume. Although autogenous bone has ... To successfully rehabilitate edentulous patients using endosseous implants, there must be enough available bone. ...
  http://www.quintpub.com/journals/omi/abstract.php?iss2_id=1254&article_id=14738&article=26&title=Recombinant%20Human%20Bone%20Morphogenetic%20Protein%202%20in%20Augmentation%20Procedures:%20Case%20Reports
*  Patent US5631142 - Compositions comprising bone morphogenetic protein-2 (BMP-2) - Google Patents
The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair. ... Purified BMP-2 proteins and processes for producing them are disclosed. ... wherein BMP is bone morphogenic protein) proteins and processes for obtaining them. These proteins may be used to induce bone ... Pharmaceutical compositions comprising bone morphogenetic protein monomers for inhibiting bone formation. US7371377. Jun 19, ...
  http://www.google.com/patents/US5631142?dq=5,072,412
*  TGF beta 2 - Wikipedia
"Bone morphogenetic protein-2 and transforming growth factor-beta2 interact to modulate human bone marrow stromal cell ... A heterogeneously glycosylated protein with high affinity and selectivity for TGF-beta ligands". J. Biol. Chem. 270 (6): 2747- ... There are two named isoforms of this protein, created by alternative splicing of the same gene. Clark DA, Coker R (1998). " ... 1990). "Transforming growth factor-beta bound to soluble derivatives of the beta amyloid precursor protein of Alzheimer's ...
  https://en.wikipedia.org/wiki/TGF_beta_2
*  Human embryonic stem cells: prospects for development | Development
Bone morphogenetic protein (BMP) 2 or BMP4, under serum-free culture conditions and in cooperation with an active gp130 ... Differentiation of human pluripotent teratocarcinoma stem cells induced by bone morphogenetic protein-2. Reprod. Fertil. Dev. ... Ying, Q. L., Nichols, J., Chambers, I. and Smith, A. (2003). BMP induction of Id proteins suppresses differentiation and ... ImaEdge - a platform for quantitative analysis of the spatiotemporal dynamics of cortical proteins during cell polarization. ...
  http://dev.biologists.org/content/131/22/5515
*  Stem cell marker - Wikipedia
"Differentiation of human pluripotent teratocarcinoma stem cells induced by bone morphogenetic protein-2". Reproduction, ... Below is a list of genes/protein products that can be used to identify various types of stem cells, or functional assays that ... Perry SS, Wang H, Pierce LJ, Yang AM, Tsai S, Spangrude GJ (April 2004). "L-selectin defines a bone marrow analog to the thymic ... Stahl J, Wobus AM, Ihrig S, Lutsch G, Bielka H (September 1992). "The small heat shock protein hsp25 is accumulated in P19 ...
  https://en.wikipedia.org/wiki/Stem_cell_marker
*  Three-Dimensional Porous Biodegradable Polymeric Scaffolds Fabricated with Biodegradable Hydrogel Porogens
Sustained release emphasizing recombinant human bone morphogenetic protein-2. Adv Drug Delivery Rev. 1998;31:303. [PubMed] ... J Bone Miner Res. 1989;4:3. [PubMed]. 24. Hanson D.P. Robb R.A. Aharon S. Augustine K.E. Cameron B.M. Camp J.J. Karwoski R.A. ... 3. Lutolf M.R. Weber F.E. Schmoekel H.G. Schense J.C. Kohler T. Muller R. Hubbell J.A. Repair of bone defects using synthetic ... The clinical needs for bone regeneration are diverse, and there are roughly one million patients who have skeletal defects each ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2819712/
*  KAKEN - Research Projects | BIOMOLECULAR STUDY ON DEGENERATION OF INTERVERTEBRAL DISK OF SENESCENCE-ACCELERATED MICE (KAKENHI...
1998 - 1999, Research Category:Grant-in-Aid for Scientific Research (C), Section:一般, Research Field:Orthopaedic surgery ... bone morphogenetic protein. Research Abstract. Temporal and spatial immunolocalization of TGF-βs, bone morphogenetic protein ( ... Publications] R.Takae,S.matunaga,N.origuchi,t.Yamamoto,N.morimoto,S.Suzuki: 'Immunolocalization of bone morphogenetic protein ... Publications] R. takae, S. Matsunaga et al.: 'Immunolocalization of bone morphogenetic protein and its receptors in ...
  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10671369/
*  The Wnt/β-catenin pathway directs neuronal differentiation of cortical neural precursor cells | Development
... bone morphogenetic protein 2 (Li et al., 1998) and erythropoietin (Shingo et al., 2001) have been implicated in the regulation ... C overnight to induce the dissociation of proteins from DNA. The proteins were eliminated by digestion with proteinase K at 45° ... In addition, the percentage of cells positive for the neuron-specific RNA-binding protein HuC/D (Sakakibara and Okano, 1997) ... Sakakibara, S. and Okano, H. (1997). Expression of neural RNA-binding proteins in the postnatal CNS: implications of their ...
  http://dev.biologists.org/content/131/12/2791
*  HOXA13 regulates the expression of bone morphogenetic proteins 2 and 7 to control distal limb morphogenesis | Development
Characterization of receptors for osteogenic protein-1/bone morphogenetic protein-7 (OP-1/BMP-7) in rat kidneys. Kidney Int. 58 ... Dudley, A. T., Lyons, K. M. and Robertson, E. J. (1995). A requirement for bone morphogenetic protein-7 during development of ... Francis, P. H., Richardson, M. K., Brickell, P. M. and Tickle, C. (1994). Bone morphogenetic proteins and a signalling pathway ... Zou, H., Wieser, R., Massague, J. and Niswander, L. (1997). Distinct roles of type I bone morphogenetic protein receptors in ...
  http://dev.biologists.org/content/131/18/4581
*  Dally regulates Dpp morphogen gradient formation in the Drosophila wing | Development
Decapentaplegic (Dpp), a Drosophila TGFβ/bone morphogenetic protein homolog, functions as a morphogen to specify cell fate ... a homolog of vertebrate bone morphogenetic proteins (BMPs). Dpp is expressed in a stripe of cells adjacent to the anterior (A)- ... a homolog of bone morphogenetic proteins 2 and 4. J. Biol. Chem. 273,29052 -29065. ... a potential mechanism for shaping bone morphogenetic protein gradients. J. Biol. Chem. 277,2089 -2096. ...
  http://dev.biologists.org/content/130/8/1515
*  A translational block to HSPG synthesis permits BMP signaling in the early Drosophila embryo | Development
... and Bone morphogenetic proteins (BMPs). Here, we show that, in Drosophila, loss of HSPGs differentially affects embryonic Hh, ... a homolog of bone morphogenetic proteins 2 and 4. J. Biol. Chem. 273,29052 -29065. ... Cleavages within the prodomain direct intracellular trafficking and degradation of mature bone morphogenetic protein-4. Mol. ... Cell-surface heparan sulfate proteoglycans potentiate chordin antagonism of bone morphogenetic protein signaling and are ...
  http://dev.biologists.org/content/135/6/1039
*  Patent US6280191 - Distractor suitable for permanent implantation into bone - Google Patents
... of bone and a means for facilitating movement of one section of anchored bone relative to another section of anchored bone. ... Furthermore, the continuous tension on the bone produced by the distractor may facilitate stimulation of osteogenesis around ... present invention relates to an osteogenic distractor suitable for indexed osteotomy following permanent implantation into bone ... Bostrom, M.P.; Camacho, N.P.; "Potential role of bone morphogenetic proteins in fracture healing."; Clin Orthop Oct. 1998; (355 ...
  http://www.google.com/patents/US6280191?dq=645576
*  PRRX1 - Wikipedia
... in developing and adult tissues in mice and regulation of its mRNA expression in osteoblasts by bone morphogenetic protein 2 ... The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus ... The protein functions as a transcription coactivator, enhancing the DNA-binding activity of serum response factor, a protein ... PRRX1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from ...
  https://en.wikipedia.org/wiki/PRRX1
*  Patent US4789732 - Bone morphogenetic protein composition - Google Patents
... and the use of such factors and compositions to induce bone formation in animals. ... for separating bone morphogenetic protein (BMP) from bone tissue. The process steps comprise demineralizing bone tissue; ... and 14-kDa associated proteins do not induce bone formation. The 17.5-kDa protein from human bone and the 18.5-kDa protein from ... Bone morphogenetic protein-3 and compositions. US6444803. 27 Nov 2000. 3 Sep 2002. Emory University. Bone mineralization ...
  http://www.google.ca/patents/US4789732
*  Patente US7429488 - Method for processing lipoaspirate cells - Google Patentes
1995). "Bone morphogenetic proteins inhibit adipocyte differentiation by bone marrow stromal cells." J Cell Biochem 58(3): 393- ... "Sequential Progression of the Differentiation Program by Bone Morphogenetic Protein-2 in Chondrogenic Cell Line ATDC5," 241:1- ... "Cellular Expression of Bone-Related Proteins During In Vitro Ostegenesis in Rat Bone Marrow Stromal Cell Culture," 158:555-572 ... Stimulatory effects of basic fibroblast growth factor and bone morphogenetic protein-2 on osteogenic differentiation of rat ...
  http://www.google.es/patents/US7429488?dq=flatulence
*  Bone Morphogenetic Protein Signaling Suppresses Tumorigenesis at Gastric Epithelial Transition Zones in Mice | Cancer Research
Bone morphogenetic protein 2 is expressed by, and acts upon, mature epithelial cells in the colon. Gastroenterology 2004; 126: ... Bone morphogenetic protein (BMP) signaling is known to suppress oncogenesis in the small and large intestine of mice and humans ... Bone Morphogenetic Protein Signaling Suppresses Tumorigenesis at Gastric Epithelial Transition Zones in Mice. Sylvia A. ... Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis. Nat Genet 2001; 28: 184-7 ...
  http://cancerres.aacrjournals.org/content/67/17/8149
*  Bone morphogenetic protein 6 - Wikipedia
Bone morphogenetic protein 6 is a protein that in humans is encoded by the BMP6 gene. The protein encoded by this gene is a ... Bone morphogenetic proteins are known for their ability to induce the growth of bone and cartilage. BMP6 is able to induce all ... The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. BMPs ... 2001). "Effect of bone morphogenetic protein-6 on haemopoietic stem cells and cytokine production in normal human bone marrow ...
  https://en.wikipedia.org/wiki/Bone_morphogenetic_protein_6
*  Bone morphogenetic protein 1 - Wikipedia
Bone morphogenetic protein 1, also known as BMP1, is a protein which in humans is encoded by the BMP1 gene. There are seven ... Although other bone morphogenetic proteins are members of the TGF-beta superfamily, BMP1 encodes a protein that is not closely ... 1993). "Mapping of the bone morphogenetic protein 1 gene (BMP1) to 8p21: removal of BMP1 from candidacy for the bone disorder ... BMP1 belongs to the peptidase M12A family of bone morphogenetic proteins (BMPs). It induces bone and cartilage development. ...
  https://en.wikipedia.org/wiki/Bone_morphogenetic_protein_1
*  Microsoft word - tepper.doc
1995) Immunolocalization and expression of bone morphogenetic proteins 2 and 4 in fracture healing. J. Orthop. Res. 13, 357-367 ... including bone morphogenetic proteins 2 and 4 and transforming growth factor-β (5, 6). However, more direct barometers of ... Pulsed electromagnetic fields simultaneously induce osteogenesis and up-regulate transcription of bone morphogenetic proteins 2 ... double-blind trial of electrical capacitive coupling in the treatment of non-union of long bones. J. Bone Joint Surg. Am. 76, ...
  http://hmamedicalclinic.com/s/sthetica.pl1.html
*  Therapeutic Relevance of Osteoprotegerin Gene Therapy in Osteosarcoma: Blockade of the Vicious Cycle between Tumor Cell...
RANKL directly induces bone morphogenetic protein-2 expression in RANK-expressing POS-1 osteosarcoma cells. Int J Oncol 2006; ... Osteoprotegerin inhibits osteoclast formation and bone resorbing activity in giant cell tumor of bone. Bone 2001; 28: 370-7. ... a naturally occurring protein that inhibits bone resorption, is very promising in blocking the vicious cycle between bone ... and the long bones exhibited high bone density as observed on radiographies, reflecting decreased bone resorption. These ...
  http://cancerres.aacrjournals.org/content/67/15/7308
*  JCI - Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter
Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter. Yoichi Miyazaki,1 Keisuke Oshima,1 ... Bone morphogenetic protein-4 is required for mesodermal formation and patterning in the mouse. Genes Dev 1995. 9:2105-2116. ... Involvement of bone morphogenetic protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse. Development 1991 ... Bone morphogenetic protein 4 (BMP4), a member of the TGF-β superfamily of secretory signaling molecules, has been implicated in ...
  https://www.jci.org/articles/view/8256
*  Expression survey of genes critical for tooth development in the human embryonic tooth germ - Lin - 2007 - Developmental...
Bone morphogenetic protein 4 is involved in cusp formation in molar tooth germ of mice. Eur J Oral Sci 110: 114-120.. Direct ... bone morphogenetic protein 2, 4, and 6) during human tooth morphogenesis. J Dent Res 73: 590-597.. *PubMed, ... 1998. A new human homeobox gene OGI2X is a member of the most conserved homeobox gene family and is expressed during heart ... 1998. The teeth as models for studies on the molecular basis of the development and evolution of organs. In: ChuongC-M, editor ...
  http://onlinelibrary.wiley.com/doi/10.1002/dvdy.21127/references
*  ̕ q ݌v w Q ƐтP X X W
Cell Res., 241, 1-11; Sequential progression of the differentiation program by bone morphogenetic protein-2 in chondrogenic ... 2. h m A ?? V A R A J S i. Chondromodulin-I ̔ p ^ [ Ƃ ̍ ` ɂ ?? . Connective Tissue, 29: 285-290, 1998.. ... Guiming Cai, Masahiro Nakayama, Yuji Hiraki, and Keiichi Ozono (1998) Am. J. Med. Gene., 78 (1), 58-60; Mutational analysis of ... Hideshi Satoh, Masakazu Susaki, Chisa Shukunami, Ken-ichi Iyama, Takaharu Negoro, and Yuji Hiraki (1998) J. Biol. Chem., 273, ...
  http://www.frontier.kyoto-u.ac.jp/te01/cd_gyouseki98.htm
*  MMP-2 plays an essential role in producing epithelial-mesenchymal transformations in the avian embryo - Duong - 2003 -...
Bone morphogenetic proteins induce apoptosis and growth factor dependence of cultured sympathoadrenal progenitor cells. Dev ... One morphogenetic event during development that is likely regulated in part by proteases is the epithelial-mesenchymal ... Proteases of cell adhesion proteins in cancer (see comments). Semin Cancer Biol 4: 251-258.. *PubMed , ... ADAM, a widely distributed and developmentally regulated gene family encoding membrane proteins with a disintegrin and ...
  http://onlinelibrary.wiley.com/doi/10.1002/dvdy.10465/full
*  Durotaxis - Wikipedia
Wang, YK; Yu, X; Cohen, DM; Wozniak, MA; Yang, MT; Gao, L; Eyckmans, J; Chen, CS (1 May 2012). "Bone morphogenetic protein-2- ... For example, bone morphogenetic protein (BMP) - a growth factor - is unable to induce osteogenesis under insufficient ... However, focal adhesions are quite more than simple anchors - their proteins have many roles in signaling. These proteins, such ... Elastin - as its name suggests - is a highly elastic protein with an important role in tissues that need to return to their ...
  https://en.wikipedia.org/wiki/Durotaxis