*  Colloidal gold - Wikipedia
"Staphylococcal protein a bound to colloidal gold: A useful reagent to label antigen-antibody sites in electron microscopy". ... The biocompatibility and high surface energy of Au allow it to bind to a large amount of protein without altering its activity ... To prevent this, one can add a stronger binding agent, like a thiol (in particular, alkanethiols), which will bind to gold, ... effects on particle size and analysis of plasma protein binding profiles". Nanomedicine: Nanotechnology, Biology and Medicine. ...
  https://en.wikipedia.org/wiki/Colloidal_gold
*  RNA-induced silencing complex - Wikipedia
TRBP is a protein with three double-stranded RNA-binding domains. Argonaute 2 is an RNase and is the catalytic centre of RISC. ... Tudor-staphylococcal nuclease; Vig, vasa intronic gene. Regardless, it is apparent that Argonaute proteins are present and are ... The RLC consists of dicer, the human immunodeficiency virus transactivating response RNA-binding protein (TRBP) and Argonaute 2 ... preventing the binding of the 60S ribosomal subunit binding to the mRNA can repress translation. Translation can be regulated ...
  https://en.wikipedia.org/wiki/RNA-induced_silencing_complex
*  Frontiers | Molecular Recognition of Gangliosides and Their Potential for Cancer Immunotherapies | Immunology
In this review, we describe how proteins recognize gangliosides, focusing on the molecular recognition of gangliosides ... In this review, we describe how proteins recognize gangliosides, focusing on the molecular recognition of gangliosides ... and also by regulating signaling proteins through lateral interaction in the membrane. Through both mechanisms, tumor- ... and also by regulating signaling proteins through lateral interaction in the membrane. Through both mechanisms, tumor- ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2014.00325/full
*  Patent US7687069 - Time release patch containing phage associated lytic enzymes for treating ... - Google Patents
Immunoglobulin a binding protein. US5571667. Jul 8, 1993. Nov 5, 1996. Chu; Albert E.. Elongated membrane flow-through ... Method of treating mastitis and other staphylococcal infections. EP0510907A2. Apr 21, 1992. Oct 28, 1992. Agricultural And Food ... Bacterial plasmin binding protein and methods of use thereof. US6238661. Apr 18, 2000. May 29, 2001. New Horizons Diagnostics ... Streptococcal immunoglobulin a binding protein encoded by emmL2.2. US5360617. Mar 13, 1991. Nov 1, 1994. Agricultural And Food ...
  http://www.google.com/patents/US7687069?dq=6948823
*  Patent US6685937 - Chewing gum containing phage associated lytic enzymes for treating ... - Google Patents
Bacterial plasmin binding protein and methods of use thereof. US6238661 *. Apr 18, 2000. May 29, 2001. New Horizons Diagnostics ... Method of treating mastitis and other staphylococcal infections. EP0510907A2. Apr 21, 1992. Oct 28, 1992. Agricultural And Food ... Fibronectin and fibrinogen binding protein from group A streptococci. US6399097 *. Sep 1, 2000. Jun 4, 2002. New Horizons ... Immunoglobulin a binding protein. US5571667. Jul 8, 1993. Nov 5, 1996. Chu; Albert E.. Elongated membrane flow-through ...
  http://www.google.com/patents/US6685937?dq=6,272,646
*  Yeast Nucleoporins Involved in Passive Nuclear Envelope Permeability | JCB
1987) A synthetic IgG-binding domain based on staphylococcal protein A. Protein Eng 1:107-113, pmid:3507693.. ... Nuclear localization signals in mRNA-binding proteins and the role of Ran and RNA. J. Biol. Chem. 274:29031-29037, pmid: ... Signal-bearing proteins are bound by soluble targeting receptors, most of which belong to the karyopherin/importin (Kap) β ... 1988) Nuclear protein migration involves two stepsrapid binding at the nuclear envelope followed by slower translocation ...
  http://jcb.rupress.org/content/149/5/1027.long
*  Viruses | Free Full-Text | Molecular Signatures of Hepatitis C Virus (HCV)-Induced Type II Mixed Cryoglobulinemia (MCII) | HTML
... the involvement of complement factors and the specific role of some HCV proteins. In this review, we will analyze the host and ... In particular, IgM molecules are good acceptors of C1q and indeed can favor indirect binding of HCV core protein to endothelial ... Domiati-Saad, R.; Attrep, J.F.; Brezinschek, H.P.; Cherrie, A.H.; Karp, D.R.; Lipsky, P.E. Staphylococcal enterotoxin d ... Ghebrehiwet, B.; Peerschke, E.I. Structure and function of gc1q-r: A multiligand binding cellular protein. Immunobiology 1998, ...
  http://www.mdpi.com/1999-4915/4/11/2924/htm
*  Virulence factors of Staphylococcus aureus strains causing infective endocarditis : a comparison with strains from skin...
... production and binding capacity to the extracellular matrix proteins: fibronectin, collagen type I, collagen type II and bone ... The potential virulence factors studied were Staphylococcal enterotoxin A-D (SEA, SEB, SEC, SED) and toxic shock syndrome toxin ... BSP binding was more often found in the control group with skin infections. Endocarditis patients with previous damage of the ... infective endocarditis, S-aureus, enterotoxin, extracellular matrix proteins, virulence factors National Category Medical and ...
  http://uu.diva-portal.org/smash/record.jsf?pid=diva2:83306
*  Patent US7078492 - Human antipneumococcal antibodies from non-human animals - Google Patents
The invention described herein provides human antibodies produced in non-human animals that specifically bind to Streptococcus ... We also screened the hybridoma supernatants for binding to staphylococcal protein A (SPA; ... protein glycosylation, protein cleavage, protein secretion, intracellular protein localization and extracellular protein homing ... "Fusion proteins" refer to chimeric proteins comprising amino acid sequences of two or more different proteins. Typically, ...
  http://www.google.com/patents/US7078492?dq=5910382
*  KAKEN - Research Projects | Elucidation of mechanisms of molecular recognition and signal transduction of immunoglobulin-Fc...
1998, Research Category:Grant-in-Aid for Scientific Research (C), Section:一般, Research Field:Physical pharmacy ... Publications] H.Gouda et al.: 'NMR study of the interaction between the B domain of Staphylococcal protein A and the Fc portion ... has completely lost the ability to bind to sFcgammaRII.We have investigated binding to sFcgammaRII of a variety of Fc analogs ... Publications] H.Gouda etal.: 'NMR study of the interaction between the B domain of Staphylococcal protein A and the Fc portion ...
  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09672186/
*  Desmoglein-1 - Wikipedia
Chen X, Bonne S, Hatzfeld M, van Roy F, Green KJ (March 2002). "Protein binding and functional characterization of plakophilin ... Hanakawa Y, Schechter NM, Lin C (2002). "Molecular mechanisms of blister formation in bullous impetigo and staphylococcal ... Chen X, Bonne S, Hatzfeld M (2002). "Protein binding and functional characterization of plakophilin 2. Evidence for its diverse ... The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus ...
  https://en.wikipedia.org/wiki/Desmoglein-1
*  Static Biofilm Cultures of Gram‐Positive Pathogens Grown in a Microtiter Format Used for Anti‐Biofilm Drug Discovery - Current...
An in vitro assay is presented for culturing staphylococcal biofilms and biofilms of nonmotile Gram‐positive bacteria under ... A novel Staphylococcus aureus biofilm phenotype mediated by the fibronectin‐binding proteins, FnBPA and FnBPB. J. Bacteriol. ... An in vitro assay is presented for culturing staphylococcal biofilms and biofilms of nonmotile Gram‐positive bacteria under ... Role of the accessory gene regulator (agr) in pathogenesis of staphylococcal osteomyelitis. Infect. Immun. 63:3373‐3380. ...
  http://www.currentprotocols.com/WileyCDA/CPUnit/refId-ph13a08.html?quicktabs_cp=abstract
*  Frontiers | Staphylococcus aureus Quorum Regulator SarA Targeted Compound, 2-[(Methylamino)methyl]phenol Inhibits Biofilm and...
Thus, inhibiting the production or blocking SarA protein might influence the down regulation of biofilm and virulence factors. ... Thus, inhibiting the production or blocking SarA protein might influence the down regulation of biofilm and virulence factors. ... Fibronectin binding protein (FnBP) is one of the essential virulence factors that favor S. aureus for its anchorage with ... Staphylococcal α-hemolysin toxins are secreted as an outcome of virulence mechanisms that are under the QS control in S. aureus ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2017.01290/full
*  Enterotoxin type B - Wikipedia
Additionally, this protein is one of the causative agents of toxic shock syndrome. The function of this protein is to ... "eMedicine - CBRNE - Staphylococcal Enterotoxin B". eMedicine. Retrieved 2011-02-06. Nema V, Agrawal R, Kamboj DV, Goel AK, ... The N-terminal domain is also referred to as OB-fold, or in other words the oligonuclucleotide binding fold. This region ... Each superantigen possesses slightly different binding mode(s) when it interacts with MHC class II molecules or the T-cell ...
  https://en.wikipedia.org/wiki/Enterotoxin_type_B
*  A Mutational Analysis of the Binding of Staphylococcal Enterotoxins B and C3 to the T Cell Receptor β Chain and Major...
1996) A mutational analysis of the binding of two different proteins to the same antibody. Biochemistry 35:9667-9776, pmid: ... staphylococcal enterotoxin A. SEB. staphylococcal enterotoxin B. SEC. staphylococcal enterotoxin C. SED. staphylococcal ... 1991) Staphylococcal toxins bind to different sites on HLA-DR. J Immunol 147:3876-3881, pmid:1940373.. ... As in the case of the wild-type proteins, the binding of all SEC3 and SEB mutants tested was characterized by very fast on- and ...
  http://jem.rupress.org/content/187/6/823
*  JCI - Antimicrobial resistance: the example of Staphylococcus aureus
I. The DNA-binding protein BlaI binds to the operator region, thus repressing RNA transcription from both blaZ and blaR1-blaI. ... Changing staphylococci and staphylococcal infections. A ten-year study of bacteria and cases of bacteremia. N. Engl. J. Med. ... mecA is responsible for synthesis of penicillin-binding protein 2a (PBP2a; also called PBP2′) a 78-kDa protein (43-45). PBPs ... Utsui, Y, Yokota, T. Role of an altered penicillin-binding protein in methicillin- and cephem-resistant Staphylococcus aureus. ...
  https://www.jci.org/articles/view/18535
*  SprD - Wikipedia
June 2008). "Interaction of human complement with Sbi, a staphylococcal immunoglobulin-binding protein: indications of a novel ... sbi protein interferes with the host's innate immune response by binding Factor H, Complement component 3 and IgG. Protein A ... SprD binds with sbi (Staphylococcus aureus binder of IgG) mRNA which encodes an immune evasion protein. It occludes the Shine- ... March 2008). "S. aureus IgG-binding proteins SpA and Sbi: host specificity and mechanisms of immune complex formation". Mol. ...
  https://en.wikipedia.org/wiki/SprD
*  Dalfopristin - Wikipedia
... conformational alterations in ribosomal target binding sites. Enzymatic drug inactivation may occur in staphylococcal and ... This complex inhibits protein synthesis through prevention of peptide-chain formation and blocking the extrusion of newly ... Initial dalfopristin binding results in a conformational change of the ribosome, allowing for increased binding by quinupristin ... Both dalfopristin and quinupristin bind to sites located on the 50S subunit of the ribosome. ...
  https://en.wikipedia.org/wiki/Dalfopristin
*  Enterotoxin - Wikipedia
These toxins share the ability to bind to the major histocompatibility complex proteins of their hosts. A more distant relative ... Staphylococcal enterotoxins and streptococcal pyrogenic exotoxins constitute a family of biologically and structurally related ... Examples include enterotoxin type B. Each superantigen possesses slightly different binding mode(s) when it interacts with MHC ... The beta-grasp domain has some structural similarities to the beta-grasp motif present in immunoglobulin-binding domains, ...
  https://en.wikipedia.org/wiki/Enterotoxin
*  Jayakar V. Nayak, MD, PhD | Stanford Medicine Profiles
These studies document the immunodominance of the VH-restricted Fab binding site on staphylococcal protein A and demonstrate ... we treated neonatal BALB/c mice with a form of staphylococcal protein A (MS) devoid of Fcgamma binding activity, which retains ... In vitro studies of several naturally occurring proteins have characterized VH family-specific B lymphocyte binding and ... B cell superantigens are proteins that are capable of immunoglobulin variable region mediated binding interactions with the ...
  https://med.stanford.edu/profiles/jayakar-nayak
*  Manipulating and enhancing the RNAi response
... encode interacting proteins; rde-4 encodes a dsRNA binding protein and rde-1 encodes a PAZ-PIWI/Argonaute protein. RDE-4 ... TSN-1contains five staphylococcal/micrococcal nuclease domain repeats, the last of which is fused to a tudor domain. Although ... The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans. Cell. 2002; ... ERI-1 contains a SAP domain found in DNA binding proteins and a DEDDh-like 3′ → 5′ exonuclease domain, which is also found in ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2737212/
*  List of biophysically important macromolecular crystal structures - Wikipedia
It was used in Anfinsen's seminal research on protein folding which led to the concept that a protein's 3-dimensional structure ... Crystallographic refinement, calcium binding site and active site at pH 7.0". Journal of Molecular Biology. 98: 693-697. doi: ... 1971 - Staphylococcal nuclease 1971 - Cytochrome C 1974 - T4 phage lysozyme 1974 - Immunoglobulins 1975 - Cu,Zn Superoxide ... repeats 2003 TOP7 protein design 2004 Cyanobacterial Circadian clock proteins 2004 Riboswitch 2006 Human exosome 2007 G-protein ...
  https://en.wikipedia.org/wiki/List_of_biophysically_important_macromolecular_crystal_structures
*  Patent US20050031626 - Binding agents with differential activity - Google Patents
This is useful if the binding agent is intended to bind both an effector cell and a target to be destroyed, because the ... whereby certain activities of a first part of the binding agent are reduced or prevented until binding to a target occurs. ... Such binding agents are useful in the treatment of cancer, for example. ... Binding agents with differential activity can be provided, ... The staphylococcal protein will usually be coupled to a solid ...
  http://www.google.com/patents/US20050031626?dq=6272333
*  METHOD FOR DOUBLE STAINING IN IMMUNOHISTOCHEMISTRY - Patent application
... receptor domain Z of staphylococcal protein A (Nord et al., "Binding Proteins Selected from Combinatorial Libraries of an α- ... binds to a nuclear marker protein for a cancer cell and the second ligand binds to a nuclear cell cycle marker protein, and ... first ligand binds to a nuclear marker protein for a cancer cell and the second ligand binds to a nuclear cell cycle marker ... affibodies for specificity for binding to marker proteins of interest. [0037]The marker proteins of interest, which are to be ...
  http://www.patentsencyclopedia.com/app/20100151447
*  Waves of Resistance: Staphylococcus aureus in the Antibiotic Era
Carbapenems and cephalosporins that bind PBP 2a, the penicillin-binding protein that mediates methicillin resistance, with much ... Prophage ΦSa3 encodes staphylokinase, staphylococcal complement inhibitor (SCIN), and S. aureus chemotaxis inhibitory protein ( ... The innate immune modulators staphylococcal complement inhibitor and chemotaxis inhibitory protein of Staphylococcus aureus are ... the methicillin resistance determinant which encodes the low affinity penicillin binding protein, PBP 2a (also referred to as ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2871281/?lang=en-ca