*  Homology of Dipteran Bristles and Lepidopteran Scales: Requirement for the Bombyx mori achaete-scute Homologue ASH2 | Genetics
Development of the Drosophila bristle is regulated by the basic helix-loop-helix (bHLH) transcription factors of the Achaete- ... we decided to investigate the potential involvement of these bHLH-type of transcription factors in the etiology of this mutant ... Zhou, Y., Q. Xiao, Z. Zhang, J. He and Y. Zhang, 2002 Foreign insect hormones stimulating the transcription of the ie-1 ... findings support our hypothesis that loss of expression of the Bm-ASH2 underlies the sl phenotype and that this bHLH factor ...
  http://www.genetics.org/content/183/2/619
*  John B. Hogenesch - Wikipedia
... studying transcription factors with basic helix-loop-helix (BHLH) and PAS protein domains. Hogenesh was mentored by Chris ... when he discovered five transcription factors in the basic helix-loop-helix-PAS (bHLH-PAS) domain superfamily during his thesis ... BMAL1 and CLOCK are now the two most well recognized bHLH-PAS domain transcription factors. Later work revealed that BMAL1 is ... These transcription factors were initially named MOP1-5. Hogenesch's later characterization of MOP3, better known as BMAL1 or ...
  https://en.wikipedia.org/wiki/John_B._Hogenesch
*  Frontiers | Carbon Monoxide Interacts with Auxin and Nitric Oxide to Cope with Iron Deficiency in Arabidopsis | Plant Science
... and the expression of Fe-uptake genes including basic helix-loop-helix transcription factor (FIT) and the ferric reduction ... and the expression of Fe-uptake genes including basic helix-loop-helix transcription factor (FIT) and the ferric reduction ... Fe-Deficiency Induced Transcription Factor 1 (FIT1) forms heterodimers with basic Helix-Loop-Helix (bHLH) 38 and bHLH39 to ... Posttranslational regulation of the iron deficiency basic helix-loop-helix transcription factor FIT is affected by iron and ...
  https://www.frontiersin.org/articles/10.3389/fpls.2016.00112/full
*  ATOH1 - Wikipedia
This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent ... "Basic helix-loop-helix transcription factor profiling of lung tumors shows aberrant expression of the proneural gene atonal ... "The intestine-specific homeobox gene Cdx2 induces expression of the basic helix-loop-helix transcription factor Math1". ... Leow CC, Polakis P, Gao WQ (Nov 2005). "A role for Hath1, a bHLH transcription factor, in colon adenocarcinoma". Annals of the ...
  https://en.wikipedia.org/wiki/ATOH1
*  Pho4 - Wikipedia
Pho4 is a basic helix-loop-helix (bHLH) transcription factor found in S. cerevisiae and other yeasts. The Pho4 homodimer binds ... Berben G, Legrain M, Gilliquet V, Hilger F (1990). "The yeast regulatory gene PHO4 encodes a helix-loop-helix motif". Yeast. 6 ... "A cysteine residue in helixII of the bHLH domain is essential for homodimerization of the yeast transcription factor Pho4p". ... "Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition". EMBO J. 16 (15): 4689-97. doi:10.1093/emboj/ ...
  https://en.wikipedia.org/wiki/Pho4
*  Meteorin: a secreted protein that regulates glial cell differentiation and promotes axonal extension | The EMBO Journal
One such mechanism is the expression of neurogenic basic helix-loop-helix (bHLH) transcription factors such as neurogenin1 and ... specific basic helix-loop-helix transcription factors. Neuron 25: 331-343. ... Several factors act in various combinations to elicit different effects on neurons. For example, hepatocyte growth factor ... Almost all cells of neurospheres maintained in the presence of fibroblast growth factor 2 (FGF2) and epidermal growth factor ( ...
  http://emboj.embopress.org/content/23/9/1998
*  Pancreas and beta-cell development: from the actual to the possible | Development
Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor. Genes Dev. 9,1009 -1019. ... This conversion is also reflected in the dynamic expression of the bHLH transcription factor neurogenin 3 (Neurog3, also known ... The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein. ... Promoter-mapping has identified putative activators of Pdx1, including the winged-helix transcription factor forkhead box A2 ( ...
  http://dev.biologists.org/content/134/3/427?ijkey=1f73b1dadaf89ac92942db940487758fe2ae15ea&keytype2=tf_ipsecsha
*  PTF1A - Wikipedia
"The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein". ... "The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine ... "Role of the basic helix-loop-helix transcription factor p48 in the differentiation phenotype of exocrine pancreas cancer cells ... McLellan AS, Langlands K, Kealey T (Dec 2002). "Exhaustive identification of human class II basic helix-loop-helix proteins by ...
  https://en.wikipedia.org/wiki/PTF1A
*  Class A basic helix-loop-helix protein 15 - Wikipedia
Pin CL, Rukstalis JM, Johnson C, Konieczny SF (2001). "The bHLH transcription factor Mist1 is required to maintain exocrine ... Class A basic helix-loop-helix protein 15 (bHLHa15) also known as class B basic helix-loop-helix protein 8 (bHLHb8) or muscle, ... 2006). "Identification of a basic helix-loop-helix transcription factor expressed in mammary gland alveolar cells and required ... 1997). "Mist1: a novel basic helix-loop-helix transcription factor exhibits a developmentally regulated expression pattern". ...
  https://en.wikipedia.org/wiki/Class_A_basic_helix-loop-helix_protein_15
*  In Vitro Generation of Early-Born Neurons from Late Retinal Progenitors | Journal of Neuroscience
Math5 encodes a murine basic helix-loop-helix transcription factor expressed during early stages of retinal neurogenesis. ... Ath5, a bHLH transcription factor, is required for the genesis of RGCs (Brown et al., 2001) and regulates Brn3b, a POU domain ... Roztocil T, Matter-Sadzinski L, Alliod C, Ballivet M, Matter JM (1997) NeuroM, a neural helix-loop-helix transcription factor, ... Vetter ML, Brown NL (2001) The role of basic helix-loop-helix genes in vertebrate retinogenesis. Semin Cell Dev Biol12 : 491- ...
  http://www.jneurosci.org/content/23/23/8193.long
*  Plus it
Neural basic helix-loop-helix (bHLH) transcription factors are crucial in regulating the differentiation and neuronal subtype ... First discovered in Drosophila, neural-specific basic-helix-loop-helix (bHLH) transcription factors are crucial for determining ... 2007) Proneural basic helix-loop-helix proteins and epidermal growth factor receptor signaling coordinately regulate cell type ... 1996) Neuronal type information encoded in the basic-helix-loop-helix domain of proneural genes. Proc Natl Acad Sci U S A 93: ...
  http://www.jneurosci.org/content/31/30/10859
*  http://ufdc.ufl.edu/UFE0021436/00001
box motif, a consensus hexanucleotide sequence found in basic helix-loop-helix (bHLH). transcriptional factors (Fairman et al ... transcription factors but are unique in that they only possess a single MYB repeat sequence. whereas other myb transcription ... a consensus hexanucleotide sequence found in basic helix-loop-helix (bHLH) transcriptional factors (Fairman et al ., 1993). ... activators are basic helix loop helix (bHLH) proteins which contain a specific region which binds. to DNA (Gekakis et al., 1998 ...
  http://ufdc.ufl.edu/UFE0021436/00001
*  ID4 - Wikipedia
Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number ... dominant negative helix-loop-helix protein". Loveys DA, Streiff MB, Kato GJ (1996). "E2A basic helix-loop-helix transcription ... Jögi A, Persson P, Grynfeld A, Påhlman S, Axelson H (2002). "Modulation of basic helix-loop-helix transcription complex ... "Helix-loop-helix proteins in Schwann cells: a study of regulation and subcellular localization of Ids, REB, and E12/47 during ...
  https://en.wikipedia.org/wiki/ID4
*  NEUROD4 gene - Semantic Scholar
Neuronal basic helix-loop-helix (bHLH) transcription factors such as neuroD and neurogenin have been shown to play important… ( ... The basic helix-loop-helix (bHLH) family of transcription factors plays an important role in the normal development and ... The NEUROGENINS (NGNs) are neural-specific basic helix-loop-helix (bHLH) transcription factors. Mouse embryos lacking ngn1 fail ... Basic helix-loop-helix transcription factor profiling of lung tumors shows aberrant expression of the proneural gene atonal ...
  https://www.semanticscholar.org/topic/NEUROD4-gene/1747726
*  Mouse Monoclonal anti-MiTF (Microphthalmia Transcription Factor) (MITF/915) | Biotium
MITF (microphthalmia transcription factor) is a basic helix-loop-helix-leucine-zipper (bHLH-Zip) transcription factor. It ... MITF (microphthalmia transcription factor) is a basic helix-loop-helix-leucine-zipper (bHLH-Zip) transcription factor that ... BHLHE32; Class E basic helix-loop-helix protein 32 (bHLHe32); CMM8; Mi; Microphthalmia-associated transcription factor; MITF; ... Age-resolving osteopetrosis: a rat model implicating microphthalmia and the related transcription factor TFE3. J. Exp.Med. 1998 ...
  https://biotium.com/product/monoclonal-anti-mitf-microphthalmia-transcription-factor-mitf915/
*  Ectopic Myf5 or MyoD prevents the neuronal differentiation program in addition to inducing skeletal muscle differentiation, in...
Skeletal muscle differentiation is crucially dependent on four basic-helix-loop-helix (bHLH) transcription factors, Myf5, MyoD ... Molecular distinction between specification and differentiation in the myogenic basic helix-loop-helix transcription factor ... neuronal bHLH transcription factors, the myogenic factor is stronger than the proneural gene in imposing its downstream ... a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD. Development 120,2385 ...
  http://dev.biologists.org/content/131/4/713
*  The bHLH-Zip transcription factor Tfeb is essential for placental vascularization | Development
Tfeb is a member of the basic Helix-Loop-Helix-Zipper family of transcription factors. In vitro studies have shown that TFEB ... The bHLH-Zip transcription factor Tfeb is essential for placental vascularization. E. Steingrimsson, L. Tessarollo, S.W. Reid, ... The bHLH-Zip transcription factor Tfeb is essential for placental vascularization Message Subject (Your Name) has sent you a ... The bHLH-Zip transcription factor Tfeb is essential for placental vascularization. E. Steingrimsson, L. Tessarollo, S.W. Reid, ...
  http://dev.biologists.org/content/125/23/4607
*  TFAP4 - Wikipedia
Transcription factor AP4 is a member of the basic helix-loop-helix (bHLH) transcription factors, which bind to the E-box ... King-Jones K, Korge G, Lehmann M (1999). "The helix-loop-helix proteins dAP-4 and daughterless bind both in vitro and in vivo ... Transcription factor AP-4 (activating enhancer binding protein 4), also known as TFAP4, is a protein which in humans is encoded ... 1991). "Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity". Genes Dev. 4 (10): ...
  https://en.wikipedia.org/wiki/TFAP4
*  ASCL2 - Wikipedia
This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by ... "A novel type of calmodulin interaction in the inhibition of basic helix-loop-helix transcription factors". Biochemistry. 39 (15 ... possible role of placenta-specific basic helix-loop-helix transcription factor, human achaete-scute homologue-2". Journal of ... Miyamoto T, Jinno Y, Miura K, Sengoku K, Soejima H, Yun K, Yaginuma Y, Niikawa N, Ishikawa M (1998). "A SacII polymorphism in ...
  https://en.wikipedia.org/wiki/ASCL2
*  A pancreatic exocrine-like cell regulatory circuit operating in the upper stomach of the sea urchin Strongylocentrotus...
Mist1: a novel basic helix-loop-helix transcription factor exhibits a developmentally regulated expression pattern. Dev Biol. ... Two members of the basic helix-loop-helix (bHLH) family of protein are known to be critical for the exocrine pancreas ... The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein. ... The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity. J ...
  https://0-bmcevolbiol-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/s12862-016-0686-0
*  TCF12 - Wikipedia
2000). "Role of the basic helix-loop-helix transcription factor p48 in the differentiation phenotype of exocrine pancreas ... The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the ... "Entrez Gene: TCF12 transcription factor 12 (HTF4, helix-loop-helix transcription factors 4)". Bain G, Murre C (1998). "The role ... a novel basic helix-loop-helix transcription factor expressed in activated B lymphocytes". Mol. Cell. Biol. 18 (6): 3130-9. PMC ...
  https://en.wikipedia.org/wiki/TCF12
*  Plus it
The bHLH (basic helix-loop-helix) transcription factor Mash1 is best known for its role in the regulation of neurogenesis. ... with the discovery of the bHLH (basic helix-loop-helix) transcription factors Olig1 and Olig2. Mice mutant for Olig2 completely ... 2000) Basic helix-loop-helix proteins and the timing of oligodendrocyte differentiation. Development 127:2989-2998. ... 2004) bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS. Science 306:2111-2115. ...
  http://www.jneurosci.org/content/27/16/4233
*  Msx1 and Msx2 act as essential activators of Atoh1 expression in the murine spinal cord | Development
... basic helix-loop-helix (bHLH) proneural TFs are induced within stripes organized along the dorsoventral axis of the neural tube ... patterns the dorsal and intermediate neural tube via regulation of homeobox and helix-loop-helix transcription factors. ... two homeodomain transcription factors (TFs), are induced earlier than bHLH neuralizing TFs. Whereas bHLH TFs have been shown to ... 2005). The bHLH factor Olig3 coordinates the specification of dorsal neurons in the spinal cord. Genes Dev. 19, 733-743. doi: ...
  http://dev.biologists.org/content/141/8/1726
*  Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons | Development
This process is regulated by the activity of transcription factors with basic helix-loop-helix (bHLH) motifs, including the ... Miyoshi, G., Bessho, Y., Yamada, S. and Kageyama, R. (2004). Identification of a novel basic helix-loop-helix gene, Heslike, ... Molecular characterization of a rat negative regulator with a basic helix-loop-helix structure predominantly expressed in the ... The HMG-box transcription factor Sox2 is expressed by most progenitors of the developing CNS, and is generally downregulated by ...
  http://dev.biologists.org/content/133/3/495
*  The three basic DNA-binding domain mutations from the associated transcription factor | High-Throughput Screen for the Chemical...
situated on murine chromosome 6p, encodes for a simple helix-loop-helix leucine zipper (bHLH-Zip) transcription element known ... The three basic DNA-binding domain mutations from the associated transcription factor. October 21, 2017. Calcium Ionophore96574 ... The three basic DNA-binding domain mutations from the associated transcription factor (Mitf), Mitfmi/mi, Mitfwh/wh and Mitfor/ ... TfeB and TfeC bHLH-Zip transcription elements and binds to E-box components on promoters of focus on genes such as for example ...
  http://acancerjourney.info/index.php/2017/10/21/the-three-basic-dna-binding-domain-mutations-from-the-associated-transcription-factor/