*  Homology of Dipteran Bristles and Lepidopteran Scales: Requirement for the Bombyx mori achaete-scute Homologue ASH2 | Genetics
Development of the Drosophila bristle is regulated by the basic helix-loop-helix (bHLH) transcription factors of the Achaete- ... we decided to investigate the potential involvement of these bHLH-type of transcription factors in the etiology of this mutant ... Zhou, Y., Q. Xiao, Z. Zhang, J. He and Y. Zhang, 2002 Foreign insect hormones stimulating the transcription of the ie-1 ... findings support our hypothesis that loss of expression of the Bm-ASH2 underlies the sl phenotype and that this bHLH factor ...
  http://www.genetics.org/content/183/2/619
*  Plus it
... basic helix-loop-helix transcription factors expressed at high levels in the developing nervous system and in morphogenetically ... It interacts with the intracellular domain of Notch1 and inhibits the action of neurogenic basic helix-loop-helix (bHLH) ... Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors. Neuron 25: ... Transcription factor 12 (Htf4/Heb/Reb), Stra13 (bHlhb2/Clast5/Sharp2/Dec1), and Olig2, belong to the helix-loop-helix class. ...
  http://www.jneurosci.org/content/24/26/5982
*  Frontiers | Identification of Norway Spruce MYB-bHLH-WDR Transcription Factor Complex Members Linked to Regulation of the...
... in particular bHLH or WDR members, has not yet been revealed. To gain knowledge about MYB-bHLH-WDR transcription factor ... in particular bHLH or WDR members, has not yet been revealed. To gain knowledge about MYB-bHLH-WDR transcription factor ... While MYB transcription factors have been previously shown to control specialized metabolism in gymnosperms, the identity of ... While MYB transcription factors have been previously shown to control specialized metabolism in gymnosperms, the identity of ...
  https://www.frontiersin.org/articles/10.3389/fpls.2017.00305/full
*  Frontiers | Carbon Monoxide Interacts with Auxin and Nitric Oxide to Cope with Iron Deficiency in Arabidopsis | Plant Science
... and the expression of Fe-uptake genes including basic helix-loop-helix transcription factor (FIT) and the ferric reduction ... and the expression of Fe-uptake genes including basic helix-loop-helix transcription factor (FIT) and the ferric reduction ... Fe-Deficiency Induced Transcription Factor 1 (FIT1) forms heterodimers with basic Helix-Loop-Helix (bHLH) 38 and bHLH39 to ... Posttranslational regulation of the iron deficiency basic helix-loop-helix transcription factor FIT is affected by iron and ...
  https://www.frontiersin.org/articles/10.3389/fpls.2016.00112/full
*  Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6 | Development
Here, the microphthalmia-associated transcription factor Mitf, which belongs to the family of basic helix-loop-helix (bHLH)/ ... Pax transcription factors as regulators of bHLH transcription factors in cellular determination. Mitf is not the first bHLH ... bHLH factors Mash1 and Math5 are not expressed (Marquardt et al., 2001). Another bHLH transcription factor, Neurod1 (previously ... During muscle development, Pax3 is involved in the activation of MyoD, a myogenic bHLH transcription factor (Maroto et al., ...
  http://dev.biologists.org/content/130/13/2903
*  John B. Hogenesch - Wikipedia
... studying transcription factors with basic helix-loop-helix (BHLH) and PAS protein domains. Hogenesh was mentored by Chris ... when he discovered five transcription factors in the basic helix-loop-helix-PAS (bHLH-PAS) domain superfamily during his thesis ... BMAL1 and CLOCK are now the two most well recognized bHLH-PAS domain transcription factors. Later work revealed that BMAL1 is ... These transcription factors were initially named MOP1-5. Hogenesch's later characterization of MOP3, better known as BMAL1 or ...
  https://en.wikipedia.org/wiki/John_B._Hogenesch
*  Meteorin: a secreted protein that regulates glial cell differentiation and promotes axonal extension | The EMBO Journal
One such mechanism is the expression of neurogenic basic helix-loop-helix (bHLH) transcription factors such as neurogenin1 and ... specific basic helix-loop-helix transcription factors. Neuron 25: 331-343. ... Several factors act in various combinations to elicit different effects on neurons. For example, hepatocyte growth factor ... Almost all cells of neurospheres maintained in the presence of fibroblast growth factor 2 (FGF2) and epidermal growth factor ( ...
  http://emboj.embopress.org/content/23/9/1998
*  ATOH1 - Wikipedia
This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent ... "Basic helix-loop-helix transcription factor profiling of lung tumors shows aberrant expression of the proneural gene atonal ... "The intestine-specific homeobox gene Cdx2 induces expression of the basic helix-loop-helix transcription factor Math1". ... Leow CC, Polakis P, Gao WQ (Nov 2005). "A role for Hath1, a bHLH transcription factor, in colon adenocarcinoma". Annals of the ...
  https://en.wikipedia.org/wiki/ATOH1
*  Pho4 - Wikipedia
Pho4 is a basic helix-loop-helix (bHLH) transcription factor found in S. cerevisiae and other yeasts. The Pho4 homodimer binds ... Berben G, Legrain M, Gilliquet V, Hilger F (1990). "The yeast regulatory gene PHO4 encodes a helix-loop-helix motif". Yeast. 6 ... "A cysteine residue in helixII of the bHLH domain is essential for homodimerization of the yeast transcription factor Pho4p". ... "Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition". EMBO J. 16 (15): 4689-97. doi:10.1093/emboj/ ...
  https://en.wikipedia.org/wiki/Pho4
*  Pancreas and beta-cell development: from the actual to the possible | Development
Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor. Genes Dev. 9,1009 -1019. ... This conversion is also reflected in the dynamic expression of the bHLH transcription factor neurogenin 3 (Neurog3, also known ... The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein. ... Promoter-mapping has identified putative activators of Pdx1, including the winged-helix transcription factor forkhead box A2 ( ...
  http://dev.biologists.org/content/134/3/427?ijkey=1f73b1dadaf89ac92942db940487758fe2ae15ea&keytype2=tf_ipsecsha
*  PTF1A - Wikipedia
"The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein". ... "The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine ... "Role of the basic helix-loop-helix transcription factor p48 in the differentiation phenotype of exocrine pancreas cancer cells ... McLellan AS, Langlands K, Kealey T (Dec 2002). "Exhaustive identification of human class II basic helix-loop-helix proteins by ...
  https://en.wikipedia.org/wiki/PTF1A
*  Plus it
Neural basic helix-loop-helix (bHLH) transcription factors are crucial in regulating the differentiation and neuronal subtype ... First discovered in Drosophila, neural-specific basic-helix-loop-helix (bHLH) transcription factors are crucial for determining ... 2007) Proneural basic helix-loop-helix proteins and epidermal growth factor receptor signaling coordinately regulate cell type ... 1996) Neuronal type information encoded in the basic-helix-loop-helix domain of proneural genes. Proc Natl Acad Sci U S A 93: ...
  http://www.jneurosci.org/content/31/30/10859
*  Class A basic helix-loop-helix protein 15 - Wikipedia
Pin CL, Rukstalis JM, Johnson C, Konieczny SF (2001). "The bHLH transcription factor Mist1 is required to maintain exocrine ... Class A basic helix-loop-helix protein 15 (bHLHa15) also known as class B basic helix-loop-helix protein 8 (bHLHb8) or muscle, ... 2006). "Identification of a basic helix-loop-helix transcription factor expressed in mammary gland alveolar cells and required ... 1997). "Mist1: a novel basic helix-loop-helix transcription factor exhibits a developmentally regulated expression pattern". ...
  https://en.wikipedia.org/wiki/Class_A_basic_helix-loop-helix_protein_15
*  In Vitro Generation of Early-Born Neurons from Late Retinal Progenitors | Journal of Neuroscience
Math5 encodes a murine basic helix-loop-helix transcription factor expressed during early stages of retinal neurogenesis. ... Ath5, a bHLH transcription factor, is required for the genesis of RGCs (Brown et al., 2001) and regulates Brn3b, a POU domain ... Roztocil T, Matter-Sadzinski L, Alliod C, Ballivet M, Matter JM (1997) NeuroM, a neural helix-loop-helix transcription factor, ... Vetter ML, Brown NL (2001) The role of basic helix-loop-helix genes in vertebrate retinogenesis. Semin Cell Dev Biol12 : 491- ...
  http://www.jneurosci.org/content/23/23/8193.long
*  Mouse Monoclonal anti-MiTF (Microphthalmia Transcription Factor) (MITF/915) | Biotium
MITF (microphthalmia transcription factor) is a basic helix-loop-helix-leucine-zipper (bHLH-Zip) transcription factor. It ... MITF (microphthalmia transcription factor) is a basic helix-loop-helix-leucine-zipper (bHLH-Zip) transcription factor that ... BHLHE32; Class E basic helix-loop-helix protein 32 (bHLHe32); CMM8; Mi; Microphthalmia-associated transcription factor; MITF; ... Age-resolving osteopetrosis: a rat model implicating microphthalmia and the related transcription factor TFE3. J. Exp.Med. 1998 ...
  https://biotium.com/product/monoclonal-anti-mitf-microphthalmia-transcription-factor-mitf915/
*  http://ufdc.ufl.edu/UFE0021436/00001
box motif, a consensus hexanucleotide sequence found in basic helix-loop-helix (bHLH). transcriptional factors (Fairman et al ... transcription factors but are unique in that they only possess a single MYB repeat sequence. whereas other myb transcription ... a consensus hexanucleotide sequence found in basic helix-loop-helix (bHLH) transcriptional factors (Fairman et al ., 1993). ... activators are basic helix loop helix (bHLH) proteins which contain a specific region which binds. to DNA (Gekakis et al., 1998 ...
  http://ufdc.ufl.edu/UFE0021436/00001
*  ID4 - Wikipedia
Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number ... dominant negative helix-loop-helix protein". Loveys DA, Streiff MB, Kato GJ (1996). "E2A basic helix-loop-helix transcription ... Jögi A, Persson P, Grynfeld A, Påhlman S, Axelson H (2002). "Modulation of basic helix-loop-helix transcription complex ... "Helix-loop-helix proteins in Schwann cells: a study of regulation and subcellular localization of Ids, REB, and E12/47 during ...
  https://en.wikipedia.org/wiki/ID4
*  NEUROD4 gene - Semantic Scholar
Neuronal basic helix-loop-helix (bHLH) transcription factors such as neuroD and neurogenin have been shown to play important… ( ... The basic helix-loop-helix (bHLH) family of transcription factors plays an important role in the normal development and ... The NEUROGENINS (NGNs) are neural-specific basic helix-loop-helix (bHLH) transcription factors. Mouse embryos lacking ngn1 fail ... Basic helix-loop-helix transcription factor profiling of lung tumors shows aberrant expression of the proneural gene atonal ...
  https://www.semanticscholar.org/topic/NEUROD4-gene/1747726
*  The bHLH-Zip transcription factor Tfeb is essential for placental vascularization | Development
Tfeb is a member of the basic Helix-Loop-Helix-Zipper family of transcription factors. In vitro studies have shown that TFEB ... The bHLH-Zip transcription factor Tfeb is essential for placental vascularization. E. Steingrimsson, L. Tessarollo, S.W. Reid, ... The bHLH-Zip transcription factor Tfeb is essential for placental vascularization Message Subject (Your Name) has sent you a ... The bHLH-Zip transcription factor Tfeb is essential for placental vascularization. E. Steingrimsson, L. Tessarollo, S.W. Reid, ...
  http://dev.biologists.org/content/125/23/4607
*  A pancreatic exocrine-like cell regulatory circuit operating in the upper stomach of the sea urchin Strongylocentrotus...
Mist1: a novel basic helix-loop-helix transcription factor exhibits a developmentally regulated expression pattern. Dev Biol. ... Two members of the basic helix-loop-helix (bHLH) family of protein are known to be critical for the exocrine pancreas ... The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein. ... The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity. J ...
  https://0-bmcevolbiol-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/s12862-016-0686-0
*  TFAP4 - Wikipedia
Transcription factor AP4 is a member of the basic helix-loop-helix (bHLH) transcription factors, which bind to the E-box ... King-Jones K, Korge G, Lehmann M (1999). "The helix-loop-helix proteins dAP-4 and daughterless bind both in vitro and in vivo ... Transcription factor AP-4 (activating enhancer binding protein 4), also known as TFAP4, is a protein which in humans is encoded ... 1991). "Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity". Genes Dev. 4 (10): ...
  https://en.wikipedia.org/wiki/TFAP4
*  ASCL2 - Wikipedia
This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by ... "A novel type of calmodulin interaction in the inhibition of basic helix-loop-helix transcription factors". Biochemistry. 39 (15 ... possible role of placenta-specific basic helix-loop-helix transcription factor, human achaete-scute homologue-2". Journal of ... Miyamoto T, Jinno Y, Miura K, Sengoku K, Soejima H, Yun K, Yaginuma Y, Niikawa N, Ishikawa M (1998). "A SacII polymorphism in ...
  https://en.wikipedia.org/wiki/ASCL2
*  A Role for Id-1 in the Aggressive Phenotype and Steroid Hormone Response of Human Breast Cancer Cells | Cancer Research
The helix-loop-helix protein Id-1 inhibits the activity of basic helix-loop-helix transcription factors, and is an important ... 4 The abbreviations used are: bHLH, basic HLH; HLH, helix-loop-helix; E2, estradiol; Pg, progesterone; ER, E2 receptor; PR, Pg ... Hxt encodes a basic helix-loop-helix transcription factor that regulates trophoblast cell development. Development (Camb.), 121 ... Tournay O., Benezra R. Transcription of the dominant-negative helix-loop-helix protein Id1 is regulated by a protein complex ...
  http://cancerres.aacrjournals.org/content/60/5/1332?ijkey=5f2caa5b49870a11f66eaf77bc6eab4e7070a98c&keytype2=tf_ipsecsha
*  Plus it
The bHLH (basic helix-loop-helix) transcription factor Mash1 is best known for its role in the regulation of neurogenesis. ... with the discovery of the bHLH (basic helix-loop-helix) transcription factors Olig1 and Olig2. Mice mutant for Olig2 completely ... 2000) Basic helix-loop-helix proteins and the timing of oligodendrocyte differentiation. Development 127:2989-2998. ... 2004) bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS. Science 306:2111-2115. ...
  http://www.jneurosci.org/content/27/16/4233
*  TCF12 - Wikipedia
2000). "Role of the basic helix-loop-helix transcription factor p48 in the differentiation phenotype of exocrine pancreas ... The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the ... "Entrez Gene: TCF12 transcription factor 12 (HTF4, helix-loop-helix transcription factors 4)". Bain G, Murre C (1998). "The role ... a novel basic helix-loop-helix transcription factor expressed in activated B lymphocytes". Mol. Cell. Biol. 18 (6): 3130-9. PMC ...
  https://en.wikipedia.org/wiki/TCF12