Because both SREBP-1 and -2 protein are portrayed generally in most cell and tissue types, the function from the homo- versus ... Keywords: glycosylphosphatidylinositol phospholipase D, diet, obesity, insulin sensitivity, women Introduction Insulin ... Weight loss with either diet did not alter plasma glycosylphosphatidylinositol-specific phospholipase D levels. However, ... Context Although circulating glycosylphosphatidylinositol-specific phospholipase D, a minor high density lipoprotein-associated ...http://www.techtasys.com/category/mglu2-receptors/
PLA2G2A - Wikipedia
"Binding of human phospholipase A2 type II to proteoglycans. Differential effect of glycosaminoglycans on enzyme activity". J. ... Phospholipase A2, membrane associated is an enzyme that in humans is encoded by the PLA2G2A gene. Phospholipase A2 GRCh38: ... 1995). "The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal ... "Entrez Gene: PLA2G2A Phospholipase A2, group IIA (platelets, synovial fluid)". Kramer RM, Johansen B, Hession C, Pepinsky RB ( ...https://en.wikipedia.org/wiki/PLA2G2A
ASMscience | Defensins and Other Anti
Secretion of type II phospholipase A2 and cryptdin by rat small intestinal Paneth cells. Infect. Immun. 64:5161-5165.. ... Bactericidal group IIA phospholipase A2 in serum of patients with bacterial infections. J. Infect. Dis. 185:1767-1772.. ... Group II phospholipase A2 in nasal fluid, mucosa and paranasal sinuses. Acta Otolaryngol. 117:860-863.. ... Defensin modulates tissue-type plasminogen activator and plasminogen binding to fibrin and endothelial cells. J. Biol. Chem. ...http://www.asmscience.org/content/book/10.1128/9781555817619.chap2
Regulation of phospholipase D activity in neuroblastoma cells
type. Contribution to journal publication status. published. subject. *Cancer and Oncology. keywords. Calmidazolium, Muscarinic ... Thus, the cholinergic activation of phospholipase D in SH-SY5Y cells is... (More). The regulation of phospholipase D was ... Regulation of phospholipase D activity in neuroblastoma cells. Gustavsson, Lena; Boyano-Adanez, Maria del Carmen; Larsson, ... The regulation of phospholipase D was studied in human neuroblastoma cells using phosphatidylethanol as a marker of the enzyme ...https://lup.lub.lu.se/search/publication/1109867
Versican - Wikipedia
Sartipy P, Bondjers G, Hurt-Camejo E (1999). "Phospholipase A2 type II binds to extracellular matrix biglycan: modulation of ... "Binding of human phospholipase A2 type II to proteoglycans. Differential effect of glycosaminoglycans on enzyme activity". J. ... The C-terminal (G3) globular domain consists of one or two Epidermal growth factor (EGF) repeats, a C-type lectin domain and ... Aspberg A, Miura R, Bourdoulous S, Shimonaka M, Heinegârd D, Schachner M, Ruoslahti E, Yamaguchi Y (1997). "The C-type lectin ...https://en.wikipedia.org/wiki/Versican
A Drosophila Model of Multiple Endocrine Neoplasia Type 2 | Genetics
... a docking site for phospholipase Cgamma. Mol. Cell. Biol. 16: 2151-2163. ... Menko, F. H., R. B. van der Luijt, I. A. de Valk, A. W. Toorians, J. M. Sepers et al., 2002 Atypical MEN type 2B associated ... 2001 Guidelines for diagnosis and therapy of MEN type 1 and type 2. J. Clin. Endocrinol. Metab. 86: 5658-5671. ... O'Riordain, D. S., T. O'Brien, T. B. Crotty, H. Gharib, C. S. Grant et al., 1995 Multiple endocrine neoplasia type 2B: more ...http://www.genetics.org/content/171/3/1057
Angiotensin II Type 2 Receptor Stimulation of Neuronal Delayed-Rectifier Potassium Current Involves Phospholipase A2 and...
Angiotensin II Type 2 Receptor Stimulation of Neuronal Delayed-Rectifier Potassium Current Involves Phospholipase A2 and ... Angiotensin II Type 2 Receptor Stimulation of Neuronal Delayed-Rectifier Potassium Current Involves Phospholipase A2 and ... Angiotensin II Type 2 Receptor Stimulation of Neuronal Delayed-Rectifier Potassium Current Involves Phospholipase A2 and ... Angiotensin II Type 2 Receptor Stimulation of Neuronal Delayed-Rectifier Potassium Current Involves Phospholipase A2 and ...http://www.jneurosci.org/content/18/2/679
ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type Iγ |...
... phosphatidylinositol 4-phosphate 5-kinase type Iγ; PLD, phospholipase D; SV, synaptic vesicles. ... Addition of wild-type ARF6-GTP resulted in an intermediate stimulation of PIP2 formation (Fig. 7 D). Collectively, our data ... Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi coated vesicles. J. Cell Biol. 134: ... Wild-type or mutant ARF6 or ARF1 GST fusion proteins were purified from bacteria according to the manufacturer's instructions ( ...http://jcb.rupress.org/content/162/1/113
Relationship between Phospholipase D Activation and Endothelial Vasomotor Dysfunction in Rabbit Aorta. David A. Cox and Marlene ... directly and potently blocks L-type Ca channels. Am. J. Physiol. 270:C1293-C1299. ... Relationship between Phospholipase D Activation and Endothelial Vasomotor Dysfunction in Rabbit Aorta. David A. Cox and Marlene ... Relationship between Phospholipase D Activation and Endothelial Vasomotor Dysfunction in Rabbit Aorta. David A. Cox and Marlene ...http://jpet.aspetjournals.org/content/283/1/305
Biosynthesis of an Endogenous Cannabinoid Precursor in Neurons and its Control by Calcium and cAMP | Journal of Neuroscience
... cleavage of NAPE by a D-type phosphodiesterase activity [phospholipase D (PLD)] may give rise to multipleN-acylethanolamines ( ... which activates CB2-type receptors in certain cell types). Although cannabimimetic NAEs may be recovered in the extracellular ... NAEs), including anandamide (which activates cannabinoid CB1-type receptors) andN-palmitoylethanolamine ( ... Journal of Neuroscience 15 June 1996, 16 (12) 3934-3942; DOI: 10.1523/JNEUROSCI.16-12-03934.1996 ...http://www.jneurosci.org/content/16/12/3934/tab-figures-data
Purification and biochemical characterization of a secreted group IIA chicken intestinal phospholipase A2 | Springer for...
Background Secretory phospholipase A2 group IIA (IIA PLA2) is a protein shown to be highly expressed in the intestine of ... Yoshikawa T, Naruse S, Kitagawa M, Ishiguro H, Nakae Y, Ono T, Hayakawa T: Effect of a new inhibitor of type II phospholipase ... Qu XD, Lloyd KC, Walsh JH, Lehrer RI: Secretion of type II phospholipase A2 and cryptdin by rat small intestinal Paneth cells. ... Bidgood MJ, Jamal OS, Cunningham AM, Brooks PM, Scott KF: Type IIA secretory phospholipase A2 up-regulates cyclooxygenase-2 and ...https://rd.springer.com/article/10.1186/1476-511X-10-27
Main Types of Clinical Appearance of Thrombophilic States During Pregnancy - Target Groups for Thrombophilia Testing |...
Main Types of Clinical Appearance of Thrombophilic States During Pregnancy - Target Groups for Thrombophilia Testing , ... "Some antiphospholipid antibodies inhibit phospholipase A2 activity." J Lab Clin Med, 1992: 67-77. ... Main Types of Clinical Appearance of Thrombophilic States During Pregnancy - Target Groups for Thrombophilia Testing. By ... Main Types of Clinical Appearance of Thrombophilic States During Pregnancy - Target Groups for Thrombophilia Testing. Ricardo ...https://www.intechopen.com/books/pregnancy-thrombophilia-the-unsuspected-risk/main-types-of-clinical-appearance-of-thrombophilic-states-during-pregnancy-target-groups-for-thrombo/
D2 Dopamine Receptors in Striatal Medium Spiny Neurons Reduce L-Type Ca2+ Currents and Excitability via a Novel PLCβ1-IP3...
Rather, D2 receptor stimulation mobilizes intracellular Ca2+ stores via Gβ γ activation of a phospholipase Cβ1 pathway, leading ... One potential target of this type of modulation is the L-type Ca2+ channel, a channel that has a privileged association with ... Why? Unlike N- and P/Q-type voltage-dependent Ca2+ channels in medium spiny neurons, L-type channels are active in the ... Dephosphorylation by calcineurin has been shown to mediate reductions in L-type Ca2+ currents in a variety of cell types (Chad ...http://www.jneurosci.org/content/20/24/8987
Protein Kinase C Function in Muscle, Liver, and β-Cells and Its Therapeutic Implications for Type 2 Diabetes | Diabetes
Zawalich WS, Zawalich KC, Kelley GG: Regulation of insulin release by phospholipase C activation in mouse islets: differential ... As in many cell types, PKCδ exerts a pro-apoptotic role in pancreatic β-cells (95,109,110). This was first shown in cytokine- ... Much of the work described above is based on the premise that inhibition of PKCs could be of benefit in the treatment of type 2 ... Protein Kinase C Function in Muscle, Liver, and β-Cells and Its Therapeutic Implications for Type 2 Diabetes. Carsten Schmitz- ...http://diabetes.diabetesjournals.org/content/57/7/1774.full.print
Diverse Functions of Secretory Phospholipases A2
K. Kugiyama, Y. Ota, K. Takazoe et al., "Circulating levels of secretory type II phospholipase A2 predict coronary events in ... M. Romano, E. Romano, S. Björkerud, and E. Hurt-Camejo, "Ultrastructural localization of secretory type II phospholipase A2 in ... N. M. Muñoz, Y. J. Kim, A. Y. Meliton et al., "Human group V phospholipase A2 induces group IVA phospholipase A2-independent ... "HDL modification by secretory phospholipase A2 promotes scavenger receptor class B type I interaction and accelerates HDL ...https://www.hindawi.com/journals/avm/2014/689815/ref/
The Multifaceted Effects of Omega-3 Polyunsaturated Fatty Acids on the Hallmarks of Cancer
B. S. Reddy, B. Simi, N. Patel, C. Aliaga, and C. V. Rao, "Effect of amount and types of dietary fat on intestinal bacterial 7α ... and phosphatidylinositol-specific phospholipase C and colonic mucosal diacylglycerol kinase and PKC activities during different ... J. Singh, R. Hamid, and B. S. Reddy, "Dietary fat and colon cancer: modulating effect of types and amount of dietary fat on ras ... J. Singh, R. Hamid, and B. S. Reddy, "Dietary fat and colon cancer: modulation of cyclooxygenase-2 by types and amount of ...https://www.hindawi.com/journals/jl/2013/261247/ref/
Clostridium novyi - Wikipedia
The type A alpha-toxin is oedematising. It acts by causing morphological changes to all cell types especially endothelial cells ... "Inhibition of receptor signaling to phospholipase D by Clostridium difficile toxin B. Role of Rho proteins". The Journal of ... It is suggested that type C may be type B that forms spores more readily so does not go through the toxin-production stage. ... It comes in three types, labelled A, B, and a non-pathogenic type C distinguished by the range of toxins they produce. Some ...https://en.wikipedia.org/wiki/Clostridium_novyi
Anovel role of phospholipase A2 in mediating spinal cord secondary injury.
Diversity of group types, regulation, and function of phospholipase A2. J Biol Chem 1994;269:13057-13060. 30. Mayer RJ, ... Phospholipase A2 and its role in brain tissue. J Neurochem 1997; 69:889 -901. 7. Bonventre JV. Roles of phospholipases A2 in ... and that the two cell types may be more vulnerable to PLA2-mediated cell death than other cell types. Because both neurons and ... Anovel role of phospholipase A2 in mediating spinal cord secondary injury.. код для вставки. код для вставки на сайт или в блог ...https://www.docme.ru/doc/1901493/anovel-role-of-phospholipase-a2-in-mediating-spinal-cord-..
PLCB4 - Wikipedia
"Exogenous human immunodeficiency virus type-1 Tat protein selectively stimulates a phosphatidylinositol-specific phospholipase ... "Entrez Gene: PLCB4 phospholipase C, beta 4". Cefai D, Debre P, Kaczorek M, et al. (1991). "Human immunodeficiency virus-1 ... "Genetic mapping of the human and mouse phospholipase C genes". Mamm. Genome. 7 (7): 501-4. doi:10.1007/s003359900151. PMID ... "cDNA sequence and gene locus of the human retinal phosphoinositide-specific phospholipase-C beta 4 (PLCB4)". Genomics. 29 (1): ...https://en.wikipedia.org/wiki/PLCB4
2005, November - Journal of Young Investigators
Type I Sec-Independent Pathway. In contrast to the type II and IV secretion pathways, type I and type III secretion are ... Shigella species, L.monocytogenes, and Rickettia have phospholipases that break down the vacuolar membrane. Once free in the ... Type II and Type IV Sec-Dependent Secretion Pathways. Type II and IV protein secretion pathways involve a separate step of ... Like the type I secretion pathway, type III secretion is independent of the sec system. (Assembly of the type III secretion ...https://www.jyi.org/2005-november
Sciorra V. A., Morris A. J. Sequential actions of Phospholipase D and type-2 phosphatidic acid phosphohydrolase generate ... role of phospholipase D and phospholipase A2. Clin. Cancer Res., 6: 2482-2491, 2000. ... Roberts R., Sciorra V. A., Morris A. J. Substrate specificity of the human type 2a, 2b and 2c and cell surface activity of the ... We and others (12 , 22) have implicated phospholipase D and cellular and secreted PLA2 in the production of LPA by ovarian ...http://clincancerres.aacrjournals.org/content/9/10/3534
PLCB1 - Wikipedia
"Exogenous human immunodeficiency virus type-1 Tat protein selectively stimulates a phosphatidylinositol-specific phospholipase ... "Entrez Gene: PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)". Runnels LW, Yue L, Clapham DE (May 2002). "The TRPM7 ... Tang Y, Tang J, Chen Z, Trost C, Flockerzi V, Li M, Ramesh V, Zhu MX (2000). "Association of mammalian trp4 and phospholipase C ... Xu A, Suh PG, Marmy-Conus N, Pearson RB, Seok OY, Cocco L, Gilmour RS (2001). "Phosphorylation of nuclear phospholipase C beta1 ...https://en.wikipedia.org/wiki/PLCB1
Denis EA (1994) Diversity of group types, regulation, and function of phospholipase A2. Journal of Biological Chemistry 269: ... Denis EA (1983) Phospholipases. In: Boyer PD (ed.) The Enzymes, 3rd edn., vol. 16, pp. 307-353. ... Fujii S, Ikeda K and Hayashi K (1998) Catalytic and toxicity mechanisms of secretory phospholipases A2. Journal of Toxicology. ... Ownby CL, Selistre de Araujo HS, White SP and Fletcher JE (1999) Lysine 49 phospholipase A2 proteins. Toxicon 37: 411-445. ...http://www.els.net/WileyCDA/ElsArticle/refId-a0000939.html
Angiotensin II Regulation of AT1 and D3 Dopamine Receptors in Renal Proximal Tubule Cells of SHR | Hypertension
Angiotensin II upregulates type-1 angiotensin II receptors in renal proximal tubule. J Clin Invest. 1995; 95: 2012-2019. ... Dopamine D1A receptor regulation of phospholipase C isoform. J Biol Chem. 1996; 271: 19503-19508. ... Dopamine decreases expression of type-1 angiotensin II receptors in renal proximal tubule. J Clin Invest. 1996; 97: 2745-2752. ... Adrenergic and endothelin B receptor-dependent hypertension in dopamine receptor type-2 knockout mice. Hypertension. 2001; 38: ...http://hyper.ahajournals.org/content/41/3/724
Cytosolic phospholipase A2 is required for cytokine-induced expression of type IIA secretory phospholipase A2 that mediates ... Dennis E. A. Diversity of group types, regulation, and function of phospholipase A2. J. Biol. Chem., 269: 13057-13060, 1994. ... Fourcade O., Le Balle F., Fauvel J., Simon M. F., Chap H. Regulation of secretory type-II phospholipase A2 and of ... Constitutive and Lysophosphatidic Acid (LPA)-induced LPA Production: Role of Phospholipase D and Phospholipase A2. Astrid M. ...http://clincancerres.aacrjournals.org/content/6/6/2482