H3K27me1 is essential for MMP-9-dependent H3N-terminal tail proteolysis during osteoclastogenesis, Epigenetics & Chromatin | 10...
Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Bergers, G; Brekken, R; McMahon, G; Vu, TH; ... Vargova V, Pytliak M, Mechirova V. Matrix metalloproteinases. Exs. paper. Additional data and materials are available from the ... Vargova V, Pytliak M, Mechirova V. Matrix metalloproteinases. Exs. paper. Additional data and materials are available from the ... ated H3K18ac neutralizes the charged lysine residue at Matrix metalloproteinases (MMPs) are a large family the primary cleavage ...https://www.deepdyve.com/lp/springer_journal/h3k27me1-is-essential-for-mmp-9-dependent-h3n-terminal-tail-LLChzJb0j9
Expression of Matrix Metalloproteinases and Their Inhibitor TIMP-1 in the Rat Carotid Artery After Balloon Injury |...
Matrix metalloproteinases and tissue inhibitor of metalloproteinases: a review of their role in tumorigenesis and tissue ... Galis ZS, Sukhova GK, Lark MW, Libby P. Increased expression of matrix metalloproteinases and matrix degrading activity in ... Matrix metalloproteinases of vascular wall cells are increased in balloon-injured rat carotid artery. J Vasc Surg. 1994;20:209- ... Expression of Matrix Metalloproteinases and Their Inhibitor TIMP-1 in the Rat Carotid Artery After Balloon Injury. Karen E. ...http://atvb.ahajournals.org/content/17/9/1837
Requirement for Matrix Metalloproteinase Stromelysin-3 in Cell Migration and Apoptosis during Tissue Remodeling in Xenopus...
... we demonstrate here that ST3 protein is specifically expressed in the cells adjacent to the remodeling extracellular matrix ( ... The matrix metalloproteinase (MMP) stromelysin-3 (ST3) was originally discovered as a gene whose expression was associated with ... Characterization of Xenopus Tissue Inhibitor of Metalloproteinases-2: A Role in Regulating Matrix Metalloproteinase Activity ... Laminin and Matrix metalloproteinase 11 regulate Fibronectin levels in the zebrafish myotendinous junction. *Molly H. Jenkins, ...https://www.semanticscholar.org/paper/Requirement-for-Matrix-Metalloproteinase-in-Cell-in-Ishizuya-Oka-Li/302620954a0feb622a9f99b5a7c9d50a5300b9a2
Matrix Metalloproteinase Inhibition Alters Functional and Structural Correlates of Deafferentation-Induced Sprouting in the...
Molecules comprising the extracellular matrix (ECM), and the family of matrix metalloproteinases (MMPs) that regulate them, ... Oligodendrocytes utilize a matrix metalloproteinase, MMP-9, to extend processes along an astrocyte extracellular matrix. Glia ... Wang X, Jung J, Asahi M, Chwang W, Russo L, Moskowitz M, Dixon CE, Fini ME, Lo EH ( 2000) Effects of matrix metalloproteinase-9 ... Yong VW, Krekoski CA, Forsyth PA, Bell R, Edwards DR ( 1998) Matrix metalloproteinases and disease of the CNS. Trends Neurosci ...http://www.jneurosci.org/content/23/32/10182?ijkey=82538be133b20d6f0a7c917eac7fc186aee84f41&keytype2=tf_ipsecsha
CiNii 論文 - Expression of matrix metalloproteinase (gelatinase) in T1 adenocarcinoma of the...
Matrix metalloproteinase 2 (MMP-2) and matrix metalloproteinase 9 (MMP-9) type IV collagenases in colorectal cancer LIABAKK N ... Complex regulation of membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation by ... Production of matrix metalloproteinase-2 and metalloproteinase-3 related to malignant behavior of esophageal carcinoma : A ... Expression of matrix metalloproteinase (gelatinase) in T1 adenocarcinoma of the lung * * Kodate Mantaro KODATE Mantaro ...https://ci.nii.ac.jp/naid/10008338797
Genetically Determined Resistance to Collagenase Action Augments Interstitial Collagen Accumulation in Atherosclerotic Plaques ...
Degradation of extracellular matrix by matrix metalloproteinases (MMPs) may play various critical roles in the progression and ... Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic ... Matrix metalloproteinases: a tail of a frog that became a prince. Nat Rev Mol Cell Biol. 2002; 3: 207-214. ... Effect of matrix metalloproteinase inhibition on progression of atherosclerosis and aneurysm in LDL receptor-deficient mice ...http://circ.ahajournals.org/content/110/14/1953
Protease-Activated Drug Development
Matrix metalloproteinase expression increases after cerebral focal ischemia in rats - inhibition of matrix metalloproteinase-9 ... methotrexate conjugates for tumor targeting via mediation by matrix metalloproteinase ii and matrix metalloproteinase ix. ... Myocardial matrix remodeling and the matrix metalloproteinases: Influence on cardiac form and function. Physiol Rev. 2007;87: ... Matrix metalloproteinases in neuroinflammation. Glia. 2002;39:279-91 211. Egeblad M, Werb Z. New functions for the matrix ...http://thno.org/v02p0156.htm
Matrix metalloproteinase - Wikipedia
MBInfo - Matrix metalloproteinases (MMPs) facilitate extracellular matrix disassembly The Matrix Metalloproteinase Protein ... "Cysteine array matrix metalloproteinase (CA-MMP)/MMP-23 is a type II transmembrane matrix metalloproteinase regulated by a ... a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase ... Matrix Metalloproteinases: Its implications in cardiovascular disorders Van Lint P, Libert C (December 2007). "Chemokine and ...https://en.wikipedia.org/wiki/Matrix_metalloproteinase
Relation of Plaque Lipid Composition and Morphology to the Stability of Human Aortic Plaques | Arteriosclerosis, Thrombosis,...
Galis ZS, Sukhova GK, Lark MW, Libby P. Increased expression of matrix metalloproteinases and matrix degrading activity in ... potential role of matrix-degrading metalloproteinases and implications for plaque rupture. Circulation. 1995;92:1565-1569. ... 18 Further dissolution of structural proteins may occur because of the release of matrix metalloproteinases from macrophage- ... may further contribute to connective tissue degradation by activating macrophages and stimulating matrix metalloproteinase ...http://atvb.ahajournals.org/content/17/7/1337.long
Anti-invasive and antiangiogenic effects of MMI-166 on malignant glioma cells | Springer for Research & Development
Background The constitutive overexpression of matrix metalloproteinases (MMPs) is frequently observed in malignant tumours. In ... Haas TL, Madri JA: Extracellular matrix-driven matrix metalloproteinase production in endothelial cells: implications for ... Bramhall SR: The matrix metalloproteinases and their inhibitors in pancreatic cancer. Int J Pancreatol. 1997, 21: 1-12.PubMed ... Tonn JC, Kerkau S, Hanke A, Bouterfa H, Mueller JG, Wagner S, Vince GH, Roosen K: Effect of synthetic matrix-metalloproteinase ...https://rd.springer.com/article/10.1186/1471-2407-10-339
Increased Secretion of Tissue Inhibitors of Metalloproteinases 1 and 2 From the Aortas of Cholesterol Fed Rabbits Partially...
Galis ZS, Sukhova GK, Lark MW, Libby P. Increased expression of matrix metalloproteinases and matrix degrading activity in ... Involvement of extracellular-matrix-degrading metalloproteinases in rabbit aortic smooth muscle cell proliferation. Biochem J. ... Expression of matrix metalloproteinases and their inhibitor TIMP-1 in the rat carotid artery after balloon injury. Arterioscler ... Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix associated protein with a distinctive pattern of ...http://atvb.ahajournals.org/content/19/7/1700
Adiponectin Specifically Increased Tissue Inhibitor of Metalloproteinase-1 Through Interleukin-10 Expression in Human...
The present study was designed to elucidate the effects of adiponectin on matrix metalloproteinases (MMPs) and tissue inhibitor ... potential role of matrix degrading metalloproteinases and implication for plaque rupture. Circulation. 1995; 92: 1565-1569. ... 1 The balance between MMPs and TIMPs determines the actual metalloproteinase activities and controls the extracellular matrix ... which are controlled by the balance between matrix metalloproteinases (MMPs) and their inhibitors (tissue inhibitor of ...http://circ.ahajournals.org/content/109/17/2046
Use of an antibody against the matrix metalloproteinasegenerated aggrecan neoepitope fvdipen-cooh to assess the effects...
Stromelysin is a matrix metalloproteinase (MMP) that has been implicated in the turnover of aggrecan from articular cartilage. ... Inhibition of matrix metalloproteinases by N-carboxyalkyl peptides. J Med Chem 36:42934301, 1993 McLean IW, Nakane PK: ... Quantification of a matrix metalloproteinase-generated aggrecan GI fragment using monospecific anti-peptide serum. Biochem J ... and to determine whether the stromelysin-generated neoepitope can be used as a marker of matrix metalloproteinase (MMP) ...https://www.docme.ru/doc/2182765/use-of-an-antibody-against-the-matrix-metalloproteinasege..
Treating Wrinkles with Dimethylaminoethanol, Retinol and Mineral Salts
16. J Varani et al, Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and ... 25. B Dreno, Oligoéléments et peau, Cosmétologie 8 44-47 (1995). 26. G Brooks, The importance of zinc in the ageing process and ... The effects of the DRMC treatment lasted until the end of the study: reductions in wrinkle grades were recorded at 17% in the ... 17. C Bertin et al, Retinol + Melibiose: An innovative anti-aging combination, 20th IFSCC Congress (1998) ...http://www.cosmeticsandtoiletries.com/formulating/function/active/219659391.html
Handling Metalloproteinases - Current Protocols
Substrate cleavage by metalloproteinases involves nucleophilic attack on the scissile peptide bond by a water molecule that is ... Control of matrix metalloproteinase catalytic activity. Matrix Biol. 26:587‐596. doi: 10.1016/j.matbio.2007.07.001. ... Matrix metalloproteinases and tissue inhibitors of metalloproteinases: Structure, function, and biochemistry. Circulation Res. ... A principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase ...http://www.currentprotocols.com/WileyCDA/CPUnit/refId-ps2116.html
Matrix Metalloproteinase-2 | SpringerLink
Type IV collagenase Matrix metalloproteinase-2 (MMP-2), previously named 72 kDa type IV collagenase or gelatinase A, belongs to ... Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function. Physiol Rev. 2007;87: ... Visse R, Nagase H. Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry ... a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase ...https://link.springer.com/referenceworkentry/10.1007%2F978-3-319-67199-4_101708
Tissue Inhibitor of Metalloproteinase-1 ( TIMP-1) Polymorphisms in a Caucasian Population with Abdominal Aortic Aneurysm |...
... is explained by the remodeling of the extracellular matrix (ECM) and breakdown of structural components of the vascular wall ... Matrix metalloproteinases are the principal matrix-degrading proteases and are known to play a major role in the remodeling of ... 1998) Matrix metalloproteinase-2 production and its binding to the matrix are increased in abdominal aortic aneurysms. Thromb ... 2006) Matrix metalloproteinase 2 polymorphisms in a caucasian population with abdominal aortic aneurysm. J Surg Res 133:121-128 ...https://link.springer.com/article/10.1007%2Fs00268-007-9209-x
Chlamydia pneumoniae and Atherosclerosis: Mechanisms of Vascular Damage | Springer for Research & Development
Galis ZS, Sukhova GK, Lark MW et al (1994) Increased expression of matrix metalloproteinases and matrix degrading activity in ... Matrix metalloproteinases and cardiovascular disease. Circ Res 77: 863-868PubMedGoogle Scholar ... Davies MJ (1998) Reactive oxygen species, metalloproteinases and plaque stability. Circulation 97: 2382-2383PubMedGoogle ... shock protein 60 localises in human atheroma and regulates macrophage tumour necrosis factor-α and matrix metalloproteinase ...https://rd.springer.com/chapter/10.1007/978-88-470-2280-5_17
Matrix Metalloproteinase-2 Production and Its Binding to the Matrix Are Increased in Abdominal Aortic Aneurysms |...
Matrix Metalloproteinase-2 Production and Its Binding to the Matrix Are Increased in Abdominal Aortic Aneurysms. Valerie Davis ... Matrix Metalloproteinase-2 Production and Its Binding to the Matrix Are Increased in Abdominal Aortic Aneurysms ... Matrix Metalloproteinase-2 Production and Its Binding to the Matrix Are Increased in Abdominal Aortic Aneurysms ... Matrix Metalloproteinase-2 Production and Its Binding to the Matrix Are Increased in Abdominal Aortic Aneurysms ...http://atvb.ahajournals.org/content/18/10/1625
IGF-1 Regulates the Extracellular Level of Active MMP-2 and Promotes Müller Glial Cell Motility | IOVS | ARVO Journals
Protein kinase C-mediated regulation of matrix metalloproteinase and tissue inhibitor of metalloproteinase production in a ... Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3. ... The role of matrix metalloproteinases in tumor invasion, metastasis, and angiogenesis. Surg Oncol Clin N Am. 2001 ; 10: 383-392 ... Matrix metalloproteinase-2 (MMP-2) regulates astrocyte motility in connection with the actin cytoskeleton and integrins. Glia. ...https://iovs.arvojournals.org/article.aspx?articleid=2468289
Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) Is Induced Upon Monocyte Differentiation and Is Expressed in Human...
Stimulation of matrix metalloproteinase production by recombinant extracellular matrix metalloproteinase inducer from ... Galis ZS, Sukhova GK, Lark MW, Libby P. Increased expression of matrix metalloproteinases and matrix degrading activity in ... Objective- Because extracellular matrix metalloproteinase inducer (EMMPRIN), a tumor cell-derived protein, induces matrix ... Potential role of matrix-degrading metalloproteinases and implications for plaque rupture. Circulation. 1995; 92: 1565-1569. ...http://atvb.ahajournals.org/content/22/7/1200
The Novartis-ILAR Rheumatology Prize 2001 Osteoarthritis: from molecule to man | Springer for Research & Development
Coordinate regulation of matrix metallopro-teases and tissue inhibitors of metalloproteinase expression in human synovial ... Dean DD, Martel-Pelletier J, Pelletier JP, Howell DS, Woessner JF: Evidence for metalloproteinase and metalloproteinase ... Elevated metalloproteinase and tissue inhibitor of metalloproteinase mRNA in human osteoarthritic synovia. J Rheumatol. 1993, ... Caron JP, Tardif G, Martel-Pelletier J, Di Battista JA, Geng C, Pelletier JP: Modulation of matrix metalloproteases 13 ( ...https://rd.springer.com/article/10.1186/ar378
Effects of inflammatory cytokine IL-27 on the activation of fibroblast-like synoviocytes in rheumatoid arthritis
Bradley K, Scatizzi JC, Shamiyeh E. Retinoblastoma suppression of matrix metalloproteinase-1, but not interleukin-6, though a p ... CXCL10 and matrix metalloproteinase-1 of RA-FLS than that of control FLS (all P , 0.05). Moreover, an additive or synergistic ... and matrix metalloproteinase production by fibroblast-like synoviocytes from rheumatoid arthritis patients. Arthritis Rheum. ... FLS can mediate cartilage and bone destruction in RA mainly via the elucidation of matrix metalloproteinases (MMPs) such as MMP ...http://pubmedcentralcanada.ca/pmcc/articles/PMC2945019/
Y-box factor YB-1 predicts drug resistance and patient outcome in breast cancer independent of clinically relevant tumor...
Matrix metalloproteinase-2 immunoreactive protein: a marker of aggressiveness in breast carcinoma. Cancer 1998;83: 1153-62.. * ... Tissue distribution of major matrix metalloproteinases and their transcripts in human breast carcinomas. Anticancer Res 1999;19 ... YB-1 regulates transcription of the matrix metalloproteinase 2 (MMP-2)/gelatinase A gene, which encodes a protease facilitating ... Expression of tumorigenesis-associated factors in normal tissue adjacent to breast cancer has been described for major matrix ...http://onlinelibrary.wiley.com/doi/10.1002/ijc.1610/full
Frontiers | Extracellular environment contribution to astrogliosis-lessons learned from a tissue engineered 3D model of the...
Besides presenting the extracellular matrix as a key modulator of astrogliosis, this simple, controlled and reproducible 3D ... can diminish astrogliosis.Besides presenting the extracellular matrix as a key modulator of astrogliosis, this simple, ... shown that chemical inhibition of RhoA with ibuprofen or indirectly targeting RhoA by the induction of extracellular matrix ... shown that chemical inhibition of RhoA with ibuprofen or indirectly targeting RhoA by the induction of extracellular matrix ...https://www.frontiersin.org/articles/10.3389/fncel.2015.00377/full