*  Antibody for PRG2 (Eosinophil Major Basic Protein) [BMK-13] - Quicktech
Eosinophil major basic protein, proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic ... Proteoglycan 2 (PRG2, also known as eosinophil major basic protein) is a protein encoded by this gene as the predominant ... and eosinophil cationic protein (EG1 and EG2) for quantifying eosinophils in bronchial biopsies from atopic asthma, Clinical ... Antibody for PRG2 (Eosinophil Major Basic Protein) [BMK-13]. Monoclonal antibody detecting PRG2, raised in mice. ...
  http://quicktech.imperialinnovations.co.uk/i/Antibodies/BMK13.html
*  Leukotriene B4 Induces Release of Antimicrobial Peptides in Lungs of Virally Infected Mice | The Journal of Immunology
Eosinophil granule proteins in peripheral blood granulocytes. J. Leukocyte Biol. 52: 611-618. ... Localization of eosinophil-derived neurotoxin and eosinophil cationic protein in neutrophilic leukocytes. J. Leukocyte Biol. 63 ... EDN is a protein of the RNase A family mostly present in eosinophils but also detected in neutrophils (29). It can be ... Eosinophil cationic protein/RNase 3 is another RNase A-family ribonuclease with direct antiviral activity. Nucleic Acids Res. ...
  http://www.jimmunol.org/content/180/9/6211
*  Mouse Eosinophils: Identification, Isolation, and Functional Analysis - Current Protocols
Eosinophils are bone marrow-derived cells that differentiate in the bone marrow and migrate into the peripheral blood primarily ... Deposition of eosinophil granule major basic protein in eosinophil gastroenteritis and celiac disease. Gastroenterology, 102, ... Tajima, K., & Katagiri, T. (1996). Deposits of eosinophil granule proteins in eosinophilic cholecystitis and eosinophilic ... Activation of basophil and mast cell histamine release by eosinophil granule major basic protein. Journal of Experimental ...
  http://www.currentprotocols.com/WileyCDA/CPUnit/refId-im1443.html?quicktabs_cp=cited
*  EP0107498A2 - Synergistic human interferon activity - Google Patents
Distinctive cationic proteins of the human eosinophil granule: major basic protein, eosinophil cationic protein, and eosinophil ... Release of granule proteins from eosinophils cultured with IL-5.. Holtmann et al. 1987. Down regulation of the receptors for ... Antiproliferative activity of a pregnancy recognition hormone, ovine trophoblast protein-1. Vadhan-Raj et al. 1986. Phase I ... The proteins in the alpha series have been shown to possess both antiviral and cell growth inhibitory effects (1-10). Similarly ...
  https://patents.google.com/patent/EP0107498A2/en
*  WAO Journal | Full text | ICON: Eosinophil Disorders
Plager DA, Stuart S, Gleich GJ: Human eosinophil granule major basic protein and its novel homolog. Allergy 1998, 53:33-40. ... including eosinophil cationic protein (ECP), eosinophil major basic proteins (MBP1 and MBP2), eosinophil peroxidase (EPO), and ... Kita H, Weiler DA, Abu-Ghazaleh R, Sanderson CJ, Gleich GJ: Release of granule proteins from eosinophils cultured with IL-5. J ... Antibacterial properties of eosinophil major basic protein and eosinophil cationic protein. J Immunol 1989, 142:4428-4434. ...
  http://www.waojournal.org/content/5/12/174
*  Eosinophil-derived neurotoxin - Wikipedia
1993). "Eosinophil granule proteins in peripheral blood granulocytes". J. Leukoc. Biol. 52 (6): 611-8. PMID 1464733. Sakakibara ... The protein encoded by this gene is found in eosinophil granulocytes. It is closely related to the eosinophil cationic protein ... 1989). "Eosinophil cationic protein cDNA. Comparison with other toxic cationic proteins and ribonucleases". J. Immunol. 143 (3 ... 1998). "Localization of eosinophil-derived neurotoxin and eosinophil cationic protein in neutrophilic leukocytes". J. Leukoc. ...
  https://en.wikipedia.org/wiki/Eosinophil-derived_neurotoxin
*  WikiGenes - Thromboembolism
Eosinophil cationic granule proteins impair thrombomodulin function. A potential mechanism for thromboembolism in ... Risk of venous thromboembolism and clinical manifestations in carriers of antithrombin, protein C, protein S deficiency, or ... Risk of venous thromboembolism and clinical manifestations in carriers of antithrombin, protein C, protein S deficiency, or ... Recurrent venous thromboembolism in patients with a partial deficiency of protein S. Comp, P.C., Esmon, C.T. N. Engl. J. Med. ( ...
  https://www.wikigenes.org/e/mesh/e/6947.html
*  Method for eliciting an immune response to human telomerase reverse transcriptase - Patent # 8709995 - PatentGenius
... the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for ... "Elevated serum levels in human pregnancy of a molecule immunochemically similar to eosinophil granule major basic protein," J. ... "A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye ... "A Human Telomeric Protein", Science, Dec. 1995, pp. 1663-1667, vol. 270. cited by applicant.. Colbere-Garapin et al., "A new ...
  http://www.patentgenius.com/patent/8709995.html
*  Intestinal Macrophage/Epithelial Cell-Derived CCL11/Eotaxin-1 Mediates Eosinophil Recruitment and Function in Pediatric...
Increased intraluminal release of eosinophil granule proteins EPO, ECP, EPX, and cytokines in ulcerative colitis and proctitis ... eosinophil peroxidase (EPO) and eosinophil-associated ribonucleases, i.e., eosinophil cationic protein (ECP) and eosinophil- ... Ultrastructural evidence for release of major basic protein-containing crystalline cores of eosinophil granules in vivo: ... Eosinophil activation in ulcerative colitis: studies on mucosal release and localization of eosinophil granule constituents. ...
  http://www.jimmunol.org/content/181/10/7390.long
*  Pemirolast - Wikipedia
... on leukotriene C4 and granule protein release from human eosinophils". Int. Arch. Allergy Immunol. 103 (4): 405-9. doi:10.1159/ ... June 1992). "Pemirolast, a new oral nonbronchodilator drug for chronic asthma". Ann Allergy. 68 (6): 488-91. PMID 1610024. ...
  https://en.wikipedia.org/wiki/Pemirolast
*  Lens and Cataract | 京都府立医科大学眼科学教室
Association of eosinophil granule major basic protein with atopic cataract. Am J Ophthalmol 122:825‐829,1996. (Yokoi N, Hirano ...
  http://www.ophth.kpu-m.ac.jp/actual_results/1992-1997/jpub7/
*  WikiGenes - GATA1 - GATA binding protein 1 (globin...
... and C/EBPepsilon isoforms regulate transcription of the gene encoding eosinophil granule major basic protein. Du, J., ... Expression of mRNA for the GATA-binding proteins in human eosinophils and basophils: potential role in gene transcription. Zon ... Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1. ... A T-cell specific TCR delta DNA binding protein is a member of the human GATA family. Joulin, V., Bories, D., Eléouet, J.F., ...
  https://www.wikigenes.org/e/gene/e/2623.html
*  Eosinophil cationic protein - Wikipedia
Eosinophil cationic protein is localized to the granule matrix of the eosinophil. The ribonuclease activity of ECP is not ... Eosinophil Cationic Protein (ECP) also known as ribonuclease 3 is a basic protein located in the eosinophil primary matrix. In ... "Antibacterial properties of eosinophil major basic protein and eosinophil cationic protein". Journal of Immunology. 142 (12): ... Nielsen LP, Peterson CG, Dahl R (2009). "Serum eosinophil granule proteins predict asthma risk in allergic rhinitis". Allergy. ...
  https://en.wikipedia.org/wiki/Eosinophil_cationic_protein
*  Automated quantitation of circulating neutrophil and eosinophil activation in asthmatic patients | Thorax
... major basic protein (MBP), and eosinophil cationic protein (ECP).4 Serum levels of these granule proteins have been used as a ... blood eosinophils, serum eosinophil cationic protein, and serum eosinophil protein X. Allergy 48:377-382, . ... Because of the highly toxic nature of the eosinophil granule proteins, excessive eosinophil activation in the circulation could ... 1988) Eosinophil granule proteins in serum after allergen challenge of asthmatic patients and the effects of anti-asthmatic ...
  http://thorax.bmj.com/content/55/6/471
*  Tissue eosinophilia in head and neck squamous neoplasia: an update | Experimental oncology
Eosinophils are multifunctional granulocytes that play an imperative role in health and disease. They have also been found to ... Eosinophils can amend the tissue remodeling process through the release of their distinct granule proteins. Eosinophil cationic ... Eosinophil fibroblast interactions granule major basic protein interacts with interleukin 1 and transforming growth -factor-b ... The role of eosi-nophils and eosinophil cationic protein in oral cancer: A review. Arch Oral Biol 2010; 56: 353-8.. 21. ...
  http://exp-oncology.com.ua/article/7060/tissue-eosinophilia-in-head-and-neck-squamous-neoplasia-an-update
*  Atopic Dermatitis - The Skin Manifestation of Atopy | Springer for Research & Development
Kapp A (1993) The role of eosinophils in the pathogenesis of atopic dermatitis - eosinophil granule proteins as markers of ... Dermal deposition of eosinophil-granule major basic protein in atopic dermatitis. Comparison with onchocerciasis. N Engl J Med ... Eosinophil cationic proteins (ECP and EPX) in health and disease. In: Yoshida T, Torisu M (eds) Immunobiology of the eosinophil ... Eosinophil involvement in atopic dermatitis as reflected by elevated serum levels of eosinophil cationic protein. J Dermatol ( ...
  https://rd.springer.com/chapter/10.1007/978-3-642-79446-9_8
*  Cutaneous Reactions to Granulocyte-Monocyte Colony-Stimulating Factor | JAMA Dermatology | JAMA Network
Staining for eosinophil granule major basic protein showed infiltration by eosinophils and extracellular deposition of major ... Eosinophils, known to release toxic products after being activated, may have a role in these skin reactions through stimulation ... eosinophils, and monocytes. We reviewed the cutaneous reactions that developed in 26 patients who received GMCSF as part of a ... Arch Dermatol. 1992;128(8):1055-1059. doi:10.1001/archderm.1992.01680180049004. Download citation file:. RIS (Zotero) EndNote ...
  https://jamanetwork.com/journals/jamadermatology/article-abstract/554285
*  Eosinophil - Wikipedia
Eosinophils produce and store many secondary granule proteins prior to their exit from the bone marrow. After maturation, ... eosinophil peroxidase, and eosinophil cationic protein are toxic to many tissues. Eosinophil cationic protein and eosinophil- ... These include: major basic protein (MBP) eosinophil cationic protein (ECP) eosinophil peroxidase (EPX) eosinophil-derived ... Following activation, eosinophils effector functions include production of: cationic granule proteins and their release by ...
  https://en.wikipedia.org/wiki/Eosinophil
*  WikiGenes - Database [Publication Type]
A novel and highly divergent homolog of human eosinophil granule major basic protein. Plager, D.A., Loegering, D.A., Weiler, D. ... An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins. Bork, P., ... hMBPH was isolated from human eosinophil granule lysates, and its identity was verified by amino acid sequencing and by mass ... The 220-kDa rim protein of retinal rod outer segments is a member of the ABC transporter superfamily. Illing, M., Molday, L.L ...
  http://www.wikigenes.org/e/mesh/e/22496.html
*  Method for treating a metastatic carcinoma using a conditionally lethal gene - Patent # 5997859 - PatentGenius
Wasmoen et al., "Biochemical and Amino Acid Sequence Analysis of Human Eosinophil Granule Major Basic Protein," J. Biol. Chem ... 255:6947-6953, 1980), pokeweed antiviral protein (Irvin, Pharmac. Ther. 21:371-387,1983), antiviral protein (Barbieri et al., ... and/or CD26 protein in their cell membrane, or from any cell type "engineered" to express such proteins. The resultant virions ... Thissurface protein can be recognized by a cytotoxic agent, such as antibodies for the reporting protein, or by cytotoxic T- ...
  http://www.patentgenius.com/patent/5997859.html
*  Major basic protein - Wikipedia
"Eosinophil granule cationic proteins: major basic protein is distinct from the smaller subunit of eosinophil peroxidase". J. ... eosinophil granule major basic protein), also known as PRG2, is a protein which in humans is encoded by the PRG2 gene. The ... 1990). "Evidence of eosinophil granule major basic protein in human placenta". J. Exp. Med. 170 (6): 2051-2063. doi:10.1084/jem ... PRG2 is a 117-residue protein that predominates in eosinophil granules. It is a potent enzyme against helminths and is toxic ...
  https://en.wikipedia.org/wiki/Major_basic_protein
*  Interleukin 5 - Wikipedia
... is the elimination of antibody bound parasites through the release of cytotoxic granule proteins. Given that eosinophils are ... "Interleukin 5 synthesis by eosinophils: association with granules and immunoglobulin-dependent secretion". J. Exp. Med. 179 (2 ... and induced sputum eosinophils have been observed. Given the high concordance of eosinophils and, in particular, allergic ... IL-5 was originally discovered as an eosinophil colony-stimulating factor, is a major regulator of eosinophil accumulation in ...
  https://en.wikipedia.org/wiki/Interleukin_5
*  Cellular and immunological markers of allergic and intrinsic bronchial asthma | SpringerLink
Eosinophil-derived products, particularly eosinophil granule proteins, have been investigated as markers of eosinophil ... Purification and characterization of a new cationic protein-eosinophil protein-X (EPX)-from granules of human eosinophils. ... Dor PJ, Ackerman SJ, Gleich GJ (1984) Charcot-Leyden crystal protein and eosinophil granule major basic protein in sputum of ... serum eosinophil cationic protein and eosinophil protein X in childhood asthma: Relation to disease status and therapy. Clin ...
  https://link.springer.com/article/10.1007%2FBF00172846
*  US Patent # 9,593,320. Proteases with modified pro regions - Patents.com
"Elevated Serum Levels in Human Pregnancy of a Molecule Immunochemically Similar to Eosinophil Granule Major Basic Protein", J. ... Variant proteins encompass naturally-occurring variants and genetically engineered variant proteins. A variant protein in the ... The terms "pro-protein", "pro-polypeptide" and "pro-protease", herein refer to a protein comprising the mature form operably ... Protein secretion across the Bacillus sp. cell envelope is a complex process that includes insertion of the precursor protein ...
  http://patents.com/us-9593320.html
*  Pregnancy-associated plasma protein A - Wikipedia
... plasma protein-A and colocalization of pregnancy-associated plasma protein-A messenger ribonucleic acid and eosinophil granule ... "Complex of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein. Disulfide structure and ... "Messenger ribonucleic acid levels of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein: ... "Circulating human pregnancy-associated plasma protein-A is disulfide-bridged to the proform of eosinophil major basic protein ...
  https://en.wikipedia.org/wiki/Pregnancy-associated_plasma_protein_A