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*  Arrhythmogenic right ventricular cardiomyopathy: Treatment and prognosis
Lemery R, Brugada P, Janssen J, et al. Nonischemic sustained ventricular tachycardia: clinical outcome in 12 patients with ... Atrial fibrillation: Anticoagulant therapy to prevent embolization. *Cardiac implantable electronic devices: Long-term ... Task Force 4: HCM and other cardiomyopathies, mitral valve prolapse, myocarditis, and Marfan syndrome. J Am Coll Cardiol 2005; ... patients with recurrent ventricular fibrillation/malignant ventricular arrhythmia syndromes besides congenital long-QT syndrome ...
  https://www.uptodate.com/contents/arrhythmogenic-right-ventricular-cardiomyopathy-treatment-and-prognosis
*  Flecainide - Wikipedia
In individuals suspected of having the Brugada syndrome, the administration of flecainide may help reveal the ECG findings that ... "Mechanism of flecainide's rate-dependent actions on action potential duration in canine atrial tissue". J Pharmacol Exp Ther. ... "Flecainide test in Brugada syndrome: a reproducible but risky tool". Pacing Clin Electrophysiol. 26 (1 Pt 2): 338-41. doi: ... and Wolff-Parkinson-White syndrome (WPW). This is because of the action of flecainide on the His-Purkinje system. It also has ...
  https://en.wikipedia.org/wiki/Flecainide
*  Brugada Syndrome Medication: Antiarrhythmic Drugs
Brugada syndrome is a disorder characterized by sudden death associated with one of several ECG patterns characterized by ... Atrial fibrillation in patients with Brugada syndrome relationships of gene mutation, electrophysiology, and clinical ... Antzelevitch C, Brugada P, Brugada J, Brugada R. Brugada syndrome: from cell to bedside. Curr Probl Cardiol. 2005 Jan. 30(1):9- ... Guideline] Antzelevitch C, Brugada P, Borggrefe M, Brugada J, Brugada R, Corrado D, et al. Brugada syndrome: report of the ...
  https://emedicine.medscape.com/article/163751-medication
*  KAKEN - Research Projects | The Mechanism of Ventricular Repolarization Abnormality and Acquired Long QT Syndrome in Chronic...
Atrial fibrillation and atrial vulnerability in patients with Brugada syndrome.'J Am Coll Cardiol. 40. 1437-1444 (2002). *. ... Atrial fibrillation and atrial vulnerability in patients with Brugada syndrome.'J Am Coll Cardiol. 40. 1437-1444 (2002). *. ... QT intervals / I(Kr) / Early afterdepolarization / extrasystoles / T wave / action potentials / Brugada syndrome / Atrial ... Publications] Morita H, Kusano-F K, Emori T et al.: 'Atrial fibrillation and atrial vulnerability in patients with Brugada ...
  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13670714/
*  Masonic Medical Research Laboratory - Wikipedia
... including sudden cardiac death syndromes such as the Long QT syndrome, Short QT syndrome, Brugada syndrome and Early ... J wave syndromes. Heart Rhythm 2010;7:549-558. Burashnikov A, Petroski A, Hu D, Barajas-Martinez H, Antzelevitch C. Atrial- ... The MMRL named this the Brugada syndrome in 1996, after Josep and Pedro Brugada, who first described this as a new clinical ... 31, 2015 "Brugada syndrome delved into in the New York Times". Medscape, Michael O'Riordan February 10, 2004 Inborn Genetic ...
  https://en.wikipedia.org/wiki/Masonic_Medical_Research_Laboratory
*  News :: Cambridge Neuroscience
... atrial and ventricular arrhythmic disorders, findings applicable to the human, arrhythmogenic, Brugada and Long QT3 syndromes ( ... Martin et al., 2012; Matthews et al., 2012), with implications for management of patients with sinus node dysfunction, atrial ... channel activation and recovery properties in producing sino-atrial pacemaker (Lei et al., 2005), ... 1992). This led to the recent view of a rapid surface action potential propagation along the muscle fibre length with only its ...
  http://www.neuroscience.cam.ac.uk/news/article.php?permalink=ade9028d8c
*  Frontiers | Bridging the gap between computation and clinical biology: validation of cable theory in humans | Physiology
... in inherited arrhythmia syndromes such as Brugada or LQT syndromes). Though simulation has been very successful at bridging a ... Final diagnoses were atrioventricular re-entrant tachycardia (5 patients), paroxysmal atrial fibrillation (1). No arrhythmia ... Brugada syndrome. Eur. Heart J. 31, 330-339. doi: 10.1093/eurheartj/ehp423 ... 2009). High-density substrate mapping in Brugada syndrome: combined role of conduction and repolarization heterogeneities in ...
  https://www.frontiersin.org/articles/10.3389/fphys.2013.00213/full
*  Burr W. Hall, M.D. - University of Rochester Medical Center
Vorobiof, G; Kroening, D; Hall, BW; Brugada, R; Huang, DT. "Brugada Syndrome with Marked Conduction Disease:Dual Implications ... He specializes in treatment of patients with atrial fibrillation, especially ablation for atrial fibrillation. He is board ... "Surgical atrial fibrillation ablation: a review of contemporary techniques and energy sources." Cardiology journal.. 2008 15(1 ... Hall graduated from Emory University in 1992, received his MD from the University of Rochester School of Medicine and Dentistry ...
  https://www.urmc.rochester.edu/people/20692353-burr-w-hall
*  Short QT Syndrome | Circulation
Brugada R, Tapscott T, Czernuszewicz GZ, et al. Identification of a genetic locus for familial atrial fibrillation. N Engl J ... Gussak I, Brugada P, Brugada J, et al. Idiopathic short QT interval: a new clinical syndrome? Cardiology. 2000; 94: 99-102. ... atrial fibrillation was induced in the patient with history of spontaneous atrial arrhythmias. In the other patient, atrial ERP ... such as congenital long QT syndrome and Brugada syndrome.2,9-11 ... Brugada J, Brugada P, Antzelevich C, et al. Long-term follow up ...
  http://circ.ahajournals.org/content/108/8/965
*  Brugada Syndrome: Current Perspectives | Springer for Research & Development
Brugada syndrome was first reported as a distinct entity in 1992. It is diagnosed by signature EKG changes including at least 2 ... Atrial fibrillation and atrial vulnerability in patients with Brugada syndrome. J Am Coll Cardiol. 2002a;40:1437-44.PubMed ... Brugada J, Brugada R, Brugada P. Electrophysiologic testing predicts events in Brugada syndrome patients. Heart Rhythm. 2011;8: ... Long-term prognosis of patients diagnosed with Brugada syndrome: results from the FINGER Brugada Syndrome Registry. Circulation ...
  https://rd.springer.com/chapter/10.1007%2F978-3-319-77812-9_8
*  Brugada syndrome - Wikipedia
The changes in heart rate induced by atrial pacing are accompanied by changes in the degree of ST segment elevation. When the ... Brugada syndrome: clinical and genetic findings. Sarquella-Brugada G1, Campuzano O2, Arbelo E3, Brugada J4, Brugada R5. Hedley ... Brugada J, Brugada P, Brugada R (July 1999). "The syndrome of right bundle branch block ST segment elevation in V1 to V3 and ... arrhythmias in Brugada syndrome patients. Patients with Brugada syndrome can prevent arrhythmias by avoiding these drugs or ...
  https://en.wikipedia.org/wiki/Brugada_syndrome
*  Sudden Cardiac Death | Circulation
A fascinating recent discovery is that the gene responsible for the Brugada syndrome, the cardiac sodium channel gene SCN5A on ... Cesium-induced atrial tachycardia degenerating into atrial fibrillation: atrial torsades de pointes? J Cardiovasc ... Brugada P, Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical ... Syndromes LQT1 through LQT5 are inherited as autosomal dominants, whereas the Jervell-Lange-Nielsen syndrome, dominant for the ...
  http://circ.ahajournals.org/content/98/21/2334.long
*  Dr. Dwain Coggins, MD - San Jose, CA - Clinical Cardiac Electrophysiology & Cardiology | Healthgrades.com
Atrial Fibrillation. *Atrial Flutter. *Autonomic Disorders. *Bradycardia. *Brugada Syndrome. *Cardiac Arrest. *Carotid Artery ... Atrial Fibrillation. Atrial Fibrillation. includes other areas of care:. - Familial Atrial Fibrillation. ... His care for my atrial flutter and later my atrial fibrillation was perfect. The two procedures were 13 years apart as they ...
  https://www.healthgrades.com/physician/dr-dwain-coggins-x3t2s?leave-review
*  ST segment elevation in the right precordial leads following administration of class Ic antiarrhythmic drugs | Heart
1999) The Brugada syndrome: clinical, electrophysiologic and genetic aspects. J Am Coll Cardiol 5:5-15. ... were administered orally for the treatment of symptomatic paroxysmal atrial fibrillation or premature atrial contractions. The ... Recently, Brugada and colleagues4 demonstrated that class I drugs could identify patients in whom the syndrome is concealed, by ... 1998) Dynamic changes of 12-lead electrocardiograms in patients with Brugada syndrome. J Cardiovasc Electrophysiol 9:508-512. ...
  http://heart.bmj.com/content/85/1/e3
*  Augmented ST-Segment Elevation During Recovery From Exercise Predicts Cardiac Events in Patients With Brugada Syndrome | JACC:...
atrial fibrillation. BrS. Brugada syndrome. ECG. electrocardiogram. EPS. electrophysiologic study. HRR. heart rate recovery. ... 2010) Long-term prognosis of patients diagnosed with Brugada syndrome: results from the FINGER Brugada syndrome registry. ... testing in group 1 Brugada syndrome patients (squares)and group 2 Brugada syndrome patients (triangles), and in control ... Brugada J.. (2003) Natural history of Brugada syndrome: the prognostic value of programmed electrical stimulation of the heart ...
  http://www.onlinejacc.org/content/56/19/1576
*  The Brugada Syndrome
... is a hereditary arrhythmic syndrome manifesting as syncope or sudden cardiac death (SCD) in individuals without overt ... Atrial fibrillation and atrial vulnerability in patients with Brugada syndrome. J Am Coll Cardiol 2002;40:1437-44.. Crossref , ... Brugada J, Brugada R, Brugada P. Electrophysiologic testing predicts events in Brugada syndrome Patients. Heart Rhythm 2011; 8: ... Rivero-Ayerza M, Brugada R, Brugada J, et al. Electrocardiogram of Brugada Syndrome and its Dynamic Patterns. In: Malik M, Camm ...
  https://www.radcliffecardiology.com/articles/brugada-syndrome-diagnosis-clinical-implications-and-risk-stratification
*  Short QT syndrome | CMAJ
Gussak I, Brugada P, Brugada J, et al. Idiopathic short QT interval: a new clinical syndrome? Cardiology 2000;94:99-102. ... Short QT syndrome and atrial fibrillation caused by mutation in KCNH2. J Cardiovasc Electrophysiol 2005;16:394-6. ... However, our understanding of cardiac arrhythmias predisposing to sudden death, like long QT syndrome, Brugada syndrome and ... Brugada R, Hong K, Dumaine R, et al. Sudden death associated with short-QT syndrome linked to mutations in HERG. Circulation ...
  http://www.cmaj.ca/content/173/11/1349.full
*  Frontiers | Mutations in the Voltage Sensors of Domains I and II of Nav1.5 that are Associated with Arrhythmias and Dilated...
Nav1.5 dysfunctions result in cardiac pathologies such as Brugada syndrome, type 3 Long QT syndrome, sick sinus syndrome, and ... Atrial flutter and non-sustained ventricular tachycardia were reported for the patient carrying the R814W mutation (Olson et al ... Nav1.5 mutations are involved in pure electrical disorders such as Brugada syndrome, type 3 long QT syndrome, and cardiac ... 2012). Mexiletine differentially restores the trafficking defects caused by two brugada syndrome mutations. Front. Pharmacol. 3 ...
  https://www.frontiersin.org/articles/10.3389/fphar.2015.00301/full
*  Antiarrhythmic agent - Wikipedia
... such as atrial fibrillation, atrial flutter, ventricular tachycardia, and ventricular fibrillation. Many attempts have been ... Brugada P (July 2000). "Magnesium: an antiarrhythmic drug, but only against very specific arrhythmias". Eur. Heart J. 21 (14): ... "Optimal administration dosage of magnesium sulfate for torsades de pointes in children with long QT syndrome". J Am Coll Nutr. ... With regards to management of atrial fibrillation, classes I and III are used in rhythm control as medical cardioversion agents ...
  https://en.wikipedia.org/wiki/Antiarrhythmic_agent
*  Gan-Xin Yan - Wikipedia
Antzelevitch C, Brugada P, Brugada J, Brugada R, Towbin JA, Nademanee K (2003). "Brugada syndrome: 1992-2002: a historical ... found that a combination of ranolazine and dronedarone can suppress atrial fibrillation. Yan played a role in the definition, ... Consisting of Brugada syndrome and early repolarization syndrome (ERS), J wave syndromes are characterized by an unusually ... Yan also published studies on the cellular basis of Brugada syndrome, potential linkages between Brugada and ERS, arrhythmic ...
  https://en.wikipedia.org/wiki/Gan-Xin_Yan
*  Cardiac Histological Substrate in Patients With Clinical Phenotype of Brugada Syndrome | Circulation
Sodium channel mutations and susceptibility to heart failure and atrial fibrillation. JAMA. 2005; 293: 447-454. ... Antzelevitch C, Brugada P, Brugada J, Brugada R, Shimizu W, Gussak I, Perez Riera AR. Brugada syndrome: a decade of progress. ... Chen Q, Kirsch GE, Zhang D, Brugada R, Brugada J, Brugada P, Potenza D, Moya A, Borggrefe M, Breithardt G, Ortiz-Lopez R, Wang ... Wilde AA, Antzelevitch C, Borggrefe M, Brugada J, Brugada R, Brugada P, Corrado D, Hauer RN, Kass RS, Nademanee K, Priori SG, ...
  http://circ.ahajournals.org/content/112/24/3680
*  The Role of Non-pore-Forming β Subunits in Physiology and Pathophysiology of Voltage-Gated Sodium Channels | SpringerLink
A missense mutation in the sodium channel beta2 subunit reveals SCN2B as a new candidate gene for Brugada syndrome. Hum Mutat ... Mutations of the SCN4B-encoded sodium channel beta4 subunit in familial atrial fibrillation. Int J Mol Med 32:144-150PubMed ... Riuro H, Beltran-Alvarez P, Tarradas A, Selga E, Campuzano O, Verges M, Pagans S, Iglesias A, Brugada J, Brugada P, Vazquez FM ... Prevalence of long-QT syndrome gene variants in sudden infant death syndrome. Circulation 115(3):361-367PubMedGoogle Scholar ...
  https://link.springer.com/chapter/10.1007/978-3-642-41588-3_4
*  The Brugada Syndrome | JACC: Journal of the American College of Cardiology
2002) Atrial fibrillation and atrial vulnerability in patients with Brugada syndrome. J Am Coll Cardiol 40:1437-1444. ... Genetic basis of Brugada syndrome. Roughly 15% to 20% of the patients with Brugada syndrome had mutations at the alpha subunit ... These studies have significantly advanced the understanding of Brugada syndrome.. Prevalence of Brugada syndrome. Though ... 2006) Atrial electrophysiological abnormality in patients with Brugada syndrome assessed by P-wave signal-averaged ECG and ...
  http://www.onlinejacc.org/content/51/12/1176
*  PPT - Cardiomyopathies PowerPoint Presentation - ID:4231242
LQTS and Brugada Syndrome are Ion Channel Disorders associated with sudden cardiac death in the young ... Biatrial enlargement with thrombi in atrial appendages common (1/3 of patients) ...
  https://www.slideserve.com/kent/cardiomyopathies
*  Pre-excitation syndrome (WPW) - Cancer Therapy Advisor
... atrial fibrillation, atrial flutter, focal atrial tachycardia, multifocal atrial tachycardia, macroreentrant atrial tachycardia ... Atié, J, Brugada, P, Brugada, J. "Clinical and electrophysiologic characteristics of patients with antidromic circus movement ... Syndromes of pre-excitation include Wolff-Parkinson-White (WPW) syndrome, concealed WPW syndrome, Lown-Ganong-Levine syndrome, ... is the most common and prototypical syndrome of the pre-excitation syndromes and from here on WPW syndrome and PES will be ...
  http://www.cancertherapyadvisor.com/hospital-medicine/pre-excitation-syndrome-wpw/article/599540/