*  Interleukin 5 - Wikipedia
Interleukin 5 has been shown to interact with Interleukin 5 receptor alpha subunit. The IL-5 receptor is composed of an α and a ... "Binding interactions of human interleukin 5 with its receptor alpha subunit. Large scale production, structural, and functional ... is an interleukin produced by type-2 T helper cells and mast cells. Through binding to the interleukin-5 receptor, interleukin ... The α subunit is specific for the IL-5 molecule, whereas the βc subunit also recognised by interleukin 3 (IL3) and granulocyte- ...
  https://en.wikipedia.org/wiki/Interleukin_5
*  Genetic and Immunologic Biomarkers in Type 1 Diabetes
Use of an antibody against the soluble interleukin 2 receptor alpha subunit can modulate the stability and biodistribution of ... Serum levels of soluble interleukin 2 receptor alpha (sIL 2R alpha) as a predictor of outcome in brucellosis J Infect 2005, 51( ... 20 cells [ 53, 5860 ] The IL 2 receptor is composed of three subunits, an alpha chain (referenced as IL2r or CD25), a beta ... the alpha subunit of the IL 2 receptor, and IL 2 itself [ 29 33 ] HLA S pecific The HLA region, a 3.6 Mb 7.6 Mb region in ...
  http://ufdc.ufl.edu/UFE0045760/00001
*  Interleukin 5 receptor alpha subunit - Wikipedia
Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 ... Interleukin 5 receptor alpha subunit has been shown to interact with: Interleukin 5, Janus kinase 2, Protein unc-119 homolog, ... The receptor is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for ... "Interleukin 5 regulates the isoform expression of its own receptor alpha-subunit". Blood. 95 (5): 1600-7. PMID 10688814. ...
  https://en.wikipedia.org/wiki/Interleukin_5_receptor_alpha_subunit
*  Human Interleukin 2 (IL-2) Promotion of Immune Regulation and ClinicalOutcomes: A Review | OMICS International
Interleukin 2 (IL-2) is a monomeric glycoprotein that is primarily produced by activated CD4+ T cells, CD8+ T cells and ... 1989) Interleukin 2 receptor beta chain gene: generation of the three receptor forms by cloned human alpha and beta chain DNAs ... Cytokine receptor subunit expression differs among various cell types. These subunits may be shared by different cytokines, ... Subunits β and γ are located in regions close to subunit α, which is the subunit that selectively binds IL-2. The gene that ...
  https://www.omicsonline.org/open-access/human-interleukin-2-il2-promotion-of-immune-regulation-and-clinicaloutcomes-a-review-.php?aid=77536
*  Alpha-1B adrenergic receptor - Wikipedia
2003). "Genetic profiling of alpha 1-adrenergic receptor subtypes by oligonucleotide microarrays: coupling to interleukin-6 ... function of Gh/transglutaminase 2 inhibits cell migration through interaction with cytoplasmic tail of integrin alpha subunits ... 1994). "Cloning, expression and characterization of human alpha adrenergic receptors alpha 1a, alpha 1b and alpha 1c". Biochem ... The alpha-1B adrenergic receptor (α1B adrenoreceptor), also known as ADRA1B, is an alpha-1 adrenergic receptor, and also ...
  https://en.wikipedia.org/wiki/Alpha-1B_adrenergic_receptor
*  Interleukin 2 - Wikipedia
... termed alpha, beta and gamma. The gamma chain is shared by all family members. The IL-2 Receptor (IL-2R) α subunit has low ... Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a protein that ... Malek TR, Castro I (August 2010). "Interleukin-2 receptor signaling: at the interface between tolerance and immunity". Immunity ... This drug binds to IL-2 receptors and introduces the diphtheria toxin into cells that express those receptors, killing the ...
  https://en.wikipedia.org/wiki/Interleukin_2
*  IL3RA - Wikipedia
Milatovich A, Kitamura T, Miyajima A, Francke U (1993). "Gene for the alpha-subunit of the human interleukin-3 receptor (IL3RA ... The receptor is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for ... "Structure of the gene encoding the alpha subunit of the human interleukin 3 receptor". Biochem. Biophys. Res. Commun. 208 (1): ... Interleukin 3 receptor, alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123), is a human gene. ...
  https://en.wikipedia.org/wiki/IL3RA
*  David B. McKay | Stanford Medicine Profiles
The high affinity receptor for interleukin-2 (IL-2) contains three subunits called IL-2R alpha, beta and gamma. A biological ... DEFINITION AND SPATIAL LOCATION OF MOUSE INTERLEUKIN-2 RESIDUES THAT INTERACT WITH ITS HETEROTRIMERIC RECEPTOR EMBO JOURNAL ... The alpha-carbon positions of 241 pairs of amino acid residues that are structurally equivalent within the two proteins can be ... The domain is built around a core scaffold, a parallel alpha-beta motif with five beta strands, that is found in other RNA and ...
  https://med.stanford.edu/profiles/david-mckay
*  Separating Transrepression and Transactivation: A Distressing Divorce for the Glucocorticoid Receptor? | Molecular Pharmacology
Induction of the E-selectin promoter by interleukin 1 and tumour necrosis factor alpha, and inhibition by glucocorticoids. ... and functional antagonism between the P65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor. Proc Natl ... Ito K, Barnes PJ, and Adcock IM (2000) Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta- ... The glucocorticoid-inducible type II IL-1 receptor (IL-1R) acts as a decoy receptor to prevent activation of the cell by IL-1. ...
  http://molpharm.aspetjournals.org/content/72/4/799.long
*  Plus it
... alpha; Ccnd1, cyclin D1; Cd151, CD151 antigen; Cox6a2, cytochrome c oxidase subunit VIa polypeptide 2; Ctsd, cathepsin D ( ... interleukin 4 receptor; Ins2, insulin; Itgam, Integrin-αM; Mgmt, O6-methylguanine-DNA methyltranferase; Mt1p1, metallothionein; ... fibroblast growth factor receptor 2; Fkh15, HNF3/forkhead homolog 5; Gal, galanin; Gstp1, glutathione-S-transferase, placental ... receptor type, epsilon polypeptide; Pygm, phosphorylase, glycogen muscle; Rnh, ribonuclease inhibitor; Scnn1b, sodium channel, ...
  http://physiolgenomics.physiology.org/content/8/1/15
*  Interleukin-6 receptor - Wikipedia
IL6R subunit is also shared by many other cytokines. Interleukin-6 receptor has been shown to interact with Interleukin 6 and ... The interleukin-6 receptor can serve as an alpha-receptor for CTNF". J. Biol. Chem. 278 (11): 9528-35. doi:10.1074/jbc. ... The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer ... Interleukin 6 receptor (IL6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. Interleukin 6 ...
  https://en.wikipedia.org/wiki/Interleukin-6_receptor
*  Mediators of Inflammation and Injury | Springer for Research & Development
Interleukin-4 down-regulates both forms of tumor necrosis factor receptor and receptor-mediated apoptosis, NF-kappaB, AP-1, and ... evidence for differential receptor subunit utilization associated with stimulation or inhibition. J Immunol 1997;159:2941-2951. ... Disparate roles for TNF-alpha and Fas ligand in convanavalin A-induced hepatitis. J Immunol 1998;160:4082-4089.PubMedGoogle ... Generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor ...
  https://rd.springer.com/chapter/10.1007/978-0-387-68113-9_4
*  Complement Receptors | Springer for Research & Development
Amino acid sequence of the alpha subunit of human leukocyte adhesion receptor Mol (complement receptor type 3), J. Cell Biol. ... Habicht, G. S., Beck, G., and Ghebrehiwet, B., 1987, C lq inhibits the expression of B lymphoblastoid cell line interleukin 1 ( ... Homology to the alpha subunits of the vitronectin and fibronectin membrane receptors, J. Biol. Chem. 262: 8476-8482.PubMed ... cDNA sequence for the aM subunit of the human neutrophil adherence receptor indicates homology to integrin a subunits, Proc. ...
  https://rd.springer.com/chapter/10.1007/978-1-4757-9534-9_9
*  Strategic gene transfer into the kidney: Current status and prospects | SpringerLink
In the kidney, the first trial of gene transfer was reported in 1991, and several... ... Cloning of cDNA for the alpha subunit of mouse insulin-like growth factor I receptor and the role of the receptor in ... Yokoo T, Kitamura M. Gene transfer of interleukin-1 receptor antagonist into the renal glomerulus via a mesangial cell vector. ... Isaka Y, Akagi Y, Kaneda Y, Yamauchi A, Orita Y, Ueda N, Imai E. Gene therapy by TGF-β-receptor-IgG Fc chimera inhibited ...
  https://link.springer.com/article/10.1007/BF02480692
*  Daniel Tenen | Harvard Catalyst Profiles | Harvard Catalyst
Interleukin-5 receptor alpha subunit gene regulation in human eosinophil development: identification of a unique cis-element ... Amino acid sequence of the alpha subunit of human leukocyte adhesion receptor Mo1 (complement receptor type 3). J Cell Biol. ... Identification and characterization of a functional promoter region in the human eosinophil IL-5 receptor alpha subunit gene. J ... Identification of Sp1-binding sites in the CD11c (p150,95 alpha) and CD11a (LFA-1 alpha) integrin subunit promoters and their ...
  https://connects.catalyst.harvard.edu/Profiles/display/Person/63164
*  WikiGenes - CSF2RA - colony stimulating factor 2 receptor,...
Gene for the alpha-subunit of the human interleukin-3 receptor (IL3RA) localized to the X-Y pseudoautosomal region. Milatovich ... Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors. ... The human pseudoautosomal GM-CSF receptor alpha subunit gene is autosomal in mouse. Disteche, C.M., Brannan, C.I., Larsen, A., ... Expression and function of the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit. Jubinsky, P.T., ...
  https://www.wikigenes.org/e/gene/e/1438.html
*  Interleukin-12 subunit beta - Wikipedia
Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and ... priming for IL-12 and tumor necrosis factor alpha production". J. Exp. Med. 181 (2): 537-46. doi:10.1084/jem.181.2.537. PMC ... IL-12B is a common subunit of interleukin 12 and Interleukin 23. This gene encodes a subunit of interleukin 12, a cytokine that ... Interleukin-12 p40 also serves as a subunit of Interleukin 23. GRCh38: Ensembl release 89: ENSG00000113302 - Ensembl, May 2017 ...
  https://en.wikipedia.org/wiki/Interleukin-12_subunit_beta
*  Ion channels in inflammation | SpringerLink
Interleukin-1 beta decreases expression of the epithelial sodium channel alpha-subunit in alveolar epithelial cells via a p38 ... The cytokine TNF-alpha increases the proportion of DRG neurons expressing the TRPV1 receptor via the TNFR1 receptor and ERK ... Bode H, Schmitz H, Fromm M, Scholz P, Riecken E-O, Schulzke J-D (1998) IL-1 beta and TNF alpha but not IFN-alpha, interferon- ... Zund G, Madara JL, Dzus AL, Awtrey CS, Colgan SP (1996) Interleukin-4 and interleukin-13 differentially regulate epithelial ...
  https://link.springer.com/article/10.1007%2Fs00424-010-0917-y
*  Warner Greene, MD, PhD | UCSF-Gladstone Center for AIDS Research (CFAR)
Regulation of interleukin 2 receptor alpha subunit (Tac or CD25 antigen) gene expression: binding of inducible nuclear proteins ... Unexpected effects of the IL-2 receptor alpha subunit on high affinity IL-2 receptor assembly and function detected with a ... Contrasting interleukin 2 binding properties of the alpha (p55) and beta (p70) protein subunits of the human high-affinity ... Activation of the interleukin-2 receptor alpha gene: regulatory role for DNA-protein interactions flanking the kappa B enhancer ...
  http://cfar.ucsf.edu/people/warner-greene?qt-admin_staff_mgnt_profile_tabs=8
*  Gene and Protein Expression Profiles in a Mouse Model of Collagen-Induced Arthritis
The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the ... T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. The Journal of experimental ... NOD-like receptor signaling pathway. 4. Irf7, Oas3, Ifi204. Ccl5. , 0.01. 9. RIG-I-like receptor signaling pathway. 3. Irf7, ... ECM-receptor interaction. 4. Fn1, Itga2, Vwf, Thbs1. , 0.001. 19. Cytokine-cytokine receptor interaction. 4. Il7r, Il2rb, Ccl5 ...
  http://www.medsci.org/v15p0077.htm
*  Interleukin 11 - Wikipedia
As a signaling molecule, interleukin 11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; ... Signal specificity is provided by the IL-11Rα subunit. Signal transduction is initiated upon binding of IL-11 to IL-11Ralpha ... receptor alpha and stoichiometry of in vitro IL-11 receptor complexes with gp130". J. Biol. Chem. 271 (48): 30986-91. doi: ... Sims NA, Jenkins BJ, Nakamura A, Quinn JM, Li R, Gillespie MT, Ernst M, Robb L, Martin TJ (July 2005). "Interleukin-11 receptor ...
  https://en.wikipedia.org/wiki/Interleukin_11
*  Physiopathology, Diagnosis, and Treatment of Secondary Female Hypogonadism | SpringerLink
Usefulness of the free alpha-subunit to diagnose hypogonadotropic hypogonadism. Clin Endocrinol. 2003;59:307-13.CrossRefGoogle ... Human peripheral blood mononuclear cells express gonadotropin-releasing hormone (GnRH), GnRH receptor, and interleukin-2 ... Mijiddorj T, Kanasaki H, Sukhbaatar U, Oride A, Kyo S. DS1, delta subunit-containing GABA(a) receptor agonist, increases ... inhibits steroid biosynthesis by cultured human granulosa-lutein cells in a CRH and interleukin-1 receptor-mediated fashion. ...
  https://link.springer.com/referenceworkentry/10.1007/978-3-319-44444-4_9
*  Method for treating a metastatic carcinoma using a conditionally lethal gene - Patent # 5997859 - PatentGenius
... alpha. or .beta. globinpromoter, T-cell receptor promoter, the osteocalcin promoter the IL-2 promoter, IL-2 receptor promoter, ... subunit of the human and mouse CD3/T-cell antigen receptor complexes," Immunogenetics 26: 258-266, 1987... Ledley, "Somatic ... An Intracellular Protein From Helper/Inducer T Cells That Regulates Gene Expression of Interleukin 2 Receptor and human ... acetyl-choline receptor promoter, alcohol dehydrogenase promoter, .alpha. or .beta. globin promoters, T-cell receptor promoter ...
  http://www.patentgenius.com/patent/5997859.html
*  Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof - Patent # 6410294 ...
... alpha subunit andtwo non-catalytic beta and gamma subunits that are believed to regulate the activity of the alpha subunit. ... form complexes with the intracellular regions of cell surface receptors. Such receptors that function through non-receptor PTKs ... and interleukin-1 (IL- 1).. PRK (proliferation-related kinase) is a serum/cytokine inducible STK that is involved in regulation ... receptor PTKs and nontransmembrane, non-receptor PTKs. Transmembrane protein-tyrosine kinases arereceptors for most growth ...
  http://www.patentgenius.com/patent/6410294.html
*  Supraspinal Glial-Neuronal Interactions Contribute to Descending Pain Facilitation
Ohtori S, Bluethmann H, Gentz R, Lesslauer W, Steinmetz M. TNF-alpha and TNF-alpha receptor type 1 upregulation in glia and ... Intrathecal interleukin-1 receptor antagonist in combination with soluble tumor necrosis factor receptor exhibits an anti- ... We have shown that glutamate receptor subunit NMDARs are widely expressed in rat RVM neurons and are upregulated and ... Interleukin-1beta enhances NMDA receptor-mediated current but inhibits excitatory synaptic transmission. Brain Res. 2005;1034: ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2660868/?lang=en-ca