*  Interleukin 5 - Wikipedia
Interleukin 5 has been shown to interact with Interleukin 5 receptor alpha subunit. The IL-5 receptor is composed of an α and a ... "Binding interactions of human interleukin 5 with its receptor alpha subunit. Large scale production, structural, and functional ... is an interleukin produced by type-2 T helper cells and mast cells. Through binding to the interleukin-5 receptor, interleukin ... The α subunit is specific for the IL-5 molecule, whereas the βc subunit also recognised by interleukin 3 (IL3) and granulocyte- ...
  https://en.wikipedia.org/wiki/Interleukin_5
*  Interleukin 5 receptor alpha subunit - Wikipedia
Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 ... Interleukin 5 receptor alpha subunit has been shown to interact with: Interleukin 5, Janus kinase 2, Protein unc-119 homolog, ... The receptor is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for ... "Interleukin 5 regulates the isoform expression of its own receptor alpha-subunit". Blood. 95 (5): 1600-7. PMID 10688814. ...
  https://en.wikipedia.org/wiki/Interleukin_5_receptor_alpha_subunit
*  Genetic and Immunologic Biomarkers in Type 1 Diabetes
Use of an antibody against the soluble interleukin 2 receptor alpha subunit can modulate the stability and biodistribution of ... Serum levels of soluble interleukin 2 receptor alpha (sIL 2R alpha) as a predictor of outcome in brucellosis J Infect 2005, 51( ... 20 cells [ 53, 5860 ] The IL 2 receptor is composed of three subunits, an alpha chain (referenced as IL2r or CD25), a beta ... the alpha subunit of the IL 2 receptor, and IL 2 itself [ 29 33 ] HLA S pecific The HLA region, a 3.6 Mb 7.6 Mb region in ...
  http://ufdc.ufl.edu/UFE0045760/00001
*  Alpha-1B adrenergic receptor - Wikipedia
2003). "Genetic profiling of alpha 1-adrenergic receptor subtypes by oligonucleotide microarrays: coupling to interleukin-6 ... function of Gh/transglutaminase 2 inhibits cell migration through interaction with cytoplasmic tail of integrin alpha subunits ... 1994). "Cloning, expression and characterization of human alpha adrenergic receptors alpha 1a, alpha 1b and alpha 1c". Biochem ... The alpha-1B adrenergic receptor (α1B adrenoreceptor), also known as ADRA1B, is an alpha-1 adrenergic receptor, and also ...
  https://en.wikipedia.org/wiki/Alpha-1B_adrenergic_receptor
*  Interleukin 2 - Wikipedia
... termed alpha, beta and gamma. The gamma chain is shared by all family members. The IL-2 Receptor (IL-2R) α subunit has low ... Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a protein that ... Malek TR, Castro I (August 2010). "Interleukin-2 receptor signaling: at the interface between tolerance and immunity". Immunity ... This drug binds to IL-2 receptors and introduces the diphtheria toxin into cells that express those receptors, killing the ...
  https://en.wikipedia.org/wiki/Interleukin_2
*  Human Interleukin 2 (IL-2) Promotion of Immune Regulation and ClinicalOutcomes: A Review | OMICS International
Interleukin 2 (IL-2) is a monomeric glycoprotein that is primarily produced by activated CD4+ T cells, CD8+ T cells and ... 1989) Interleukin 2 receptor beta chain gene: generation of the three receptor forms by cloned human alpha and beta chain DNAs ... Cytokine receptor subunit expression differs among various cell types. These subunits may be shared by different cytokines, ... Subunits β and γ are located in regions close to subunit α, which is the subunit that selectively binds IL-2. The gene that ...
  https://www.omicsonline.org/open-access/human-interleukin-2-il2-promotion-of-immune-regulation-and-clinicaloutcomes-a-review-.php?aid=77536
*  IL3RA - Wikipedia
Milatovich A, Kitamura T, Miyajima A, Francke U (1993). "Gene for the alpha-subunit of the human interleukin-3 receptor (IL3RA ... The receptor is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for ... "Structure of the gene encoding the alpha subunit of the human interleukin 3 receptor". Biochem. Biophys. Res. Commun. 208 (1): ... Interleukin 3 receptor, alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123), is a human gene. ...
  https://en.wikipedia.org/wiki/IL3RA
*  Interleukin-6 receptor - Wikipedia
IL6R subunit is also shared by many other cytokines. Interleukin-6 receptor has been shown to interact with Interleukin 6 and ... The interleukin-6 receptor can serve as an alpha-receptor for CTNF". J. Biol. Chem. 278 (11): 9528-35. doi:10.1074/jbc. ... The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer ... Interleukin 6 receptor (IL6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. Interleukin 6 ...
  https://en.wikipedia.org/wiki/Interleukin-6_receptor
*  David B. McKay | Stanford Medicine Profiles
The high affinity receptor for interleukin-2 (IL-2) contains three subunits called IL-2R alpha, beta and gamma. A biological ... DEFINITION AND SPATIAL LOCATION OF MOUSE INTERLEUKIN-2 RESIDUES THAT INTERACT WITH ITS HETEROTRIMERIC RECEPTOR EMBO JOURNAL ... The alpha-carbon positions of 241 pairs of amino acid residues that are structurally equivalent within the two proteins can be ... The domain is built around a core scaffold, a parallel alpha-beta motif with five beta strands, that is found in other RNA and ...
  https://med.stanford.edu/profiles/david-mckay
*  Plus it
... alpha; Ccnd1, cyclin D1; Cd151, CD151 antigen; Cox6a2, cytochrome c oxidase subunit VIa polypeptide 2; Ctsd, cathepsin D ( ... interleukin 4 receptor; Ins2, insulin; Itgam, Integrin-αM; Mgmt, O6-methylguanine-DNA methyltranferase; Mt1p1, metallothionein; ... fibroblast growth factor receptor 2; Fkh15, HNF3/forkhead homolog 5; Gal, galanin; Gstp1, glutathione-S-transferase, placental ... receptor type, epsilon polypeptide; Pygm, phosphorylase, glycogen muscle; Rnh, ribonuclease inhibitor; Scnn1b, sodium channel, ...
  http://physiolgenomics.physiology.org/content/8/1/15
*  Separating Transrepression and Transactivation: A Distressing Divorce for the Glucocorticoid Receptor? | Molecular Pharmacology
Induction of the E-selectin promoter by interleukin 1 and tumour necrosis factor alpha, and inhibition by glucocorticoids. ... and functional antagonism between the P65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor. Proc Natl ... Ito K, Barnes PJ, and Adcock IM (2000) Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta- ... The glucocorticoid-inducible type II IL-1 receptor (IL-1R) acts as a decoy receptor to prevent activation of the cell by IL-1. ...
  http://molpharm.aspetjournals.org/content/72/4/799.long
*  Interleukin-12 subunit beta - Wikipedia
Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and ... priming for IL-12 and tumor necrosis factor alpha production". J. Exp. Med. 181 (2): 537-46. doi:10.1084/jem.181.2.537. PMC ... IL-12B is a common subunit of interleukin 12 and Interleukin 23. This gene encodes a subunit of interleukin 12, a cytokine that ... Interleukin-12 p40 also serves as a subunit of Interleukin 23. GRCh38: Ensembl release 89: ENSG00000113302 - Ensembl, May 2017 ...
  https://en.wikipedia.org/wiki/Interleukin-12_subunit_beta
*  Interleukin 11 - Wikipedia
As a signaling molecule, interleukin 11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; ... Signal specificity is provided by the IL-11Rα subunit. Signal transduction is initiated upon binding of IL-11 to IL-11Ralpha ... receptor alpha and stoichiometry of in vitro IL-11 receptor complexes with gp130". J. Biol. Chem. 271 (48): 30986-91. doi: ... Sims NA, Jenkins BJ, Nakamura A, Quinn JM, Li R, Gillespie MT, Ernst M, Robb L, Martin TJ (July 2005). "Interleukin-11 receptor ...
  https://en.wikipedia.org/wiki/Interleukin_11
*  Daniel Tenen | Harvard Catalyst Profiles | Harvard Catalyst
Interleukin-5 receptor alpha subunit gene regulation in human eosinophil development: identification of a unique cis-element ... Amino acid sequence of the alpha subunit of human leukocyte adhesion receptor Mo1 (complement receptor type 3). J Cell Biol. ... Identification and characterization of a functional promoter region in the human eosinophil IL-5 receptor alpha subunit gene. J ... Identification of Sp1-binding sites in the CD11c (p150,95 alpha) and CD11a (LFA-1 alpha) integrin subunit promoters and their ...
  https://connects.catalyst.harvard.edu/Profiles/display/Person/63164
*  Strategic gene transfer into the kidney: Current status and prospects | SpringerLink
In the kidney, the first trial of gene transfer was reported in 1991, and several... ... Cloning of cDNA for the alpha subunit of mouse insulin-like growth factor I receptor and the role of the receptor in ... Yokoo T, Kitamura M. Gene transfer of interleukin-1 receptor antagonist into the renal glomerulus via a mesangial cell vector. ... Isaka Y, Akagi Y, Kaneda Y, Yamauchi A, Orita Y, Ueda N, Imai E. Gene therapy by TGF-β-receptor-IgG Fc chimera inhibited ...
  https://link.springer.com/article/10.1007/BF02480692
*  Warner Greene, MD, PhD | UCSF-Gladstone Center for AIDS Research (CFAR)
Regulation of interleukin 2 receptor alpha subunit (Tac or CD25 antigen) gene expression: binding of inducible nuclear proteins ... Unexpected effects of the IL-2 receptor alpha subunit on high affinity IL-2 receptor assembly and function detected with a ... Contrasting interleukin 2 binding properties of the alpha (p55) and beta (p70) protein subunits of the human high-affinity ... Activation of the interleukin-2 receptor alpha gene: regulatory role for DNA-protein interactions flanking the kappa B enhancer ...
  http://cfar.ucsf.edu/people/warner-greene?qt-admin_staff_mgnt_profile_tabs=8
*  Estrogen receptor alpha - Wikipedia
Stein B, Yang MX (Sep 1995). "Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa B and C/EBP ... complex interacts directly with estrogen receptors α and β through the TRAP220 subunit and directly enhances estrogen receptor ... "The aryl hydrocarbon receptor interacts with estrogen receptor alpha and orphan receptors COUP-TFI and ERRalpha1". Arch. ... Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types ...
  https://en.wikipedia.org/wiki/Estrogen_receptor_alpha
*  Gene and Protein Expression Profiles in a Mouse Model of Collagen-Induced Arthritis
The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the ... T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. The Journal of experimental ... NOD-like receptor signaling pathway. 4. Irf7, Oas3, Ifi204. Ccl5. , 0.01. 9. RIG-I-like receptor signaling pathway. 3. Irf7, ... ECM-receptor interaction. 4. Fn1, Itga2, Vwf, Thbs1. , 0.001. 19. Cytokine-cytokine receptor interaction. 4. Il7r, Il2rb, Ccl5 ...
  http://www.medsci.org/v15p0077.htm
*  Ubiquitin C - Wikipedia
"Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB ... Kawahara K, Hashimoto M, Bar-On P, Ho GJ, Crews L, Mizuno H, Rockenstein E, Imam SZ, Masliah E (March 2008). "alpha-Synuclein ... Raikwar NS, Thomas CP (May 2008). "Nedd4-2 isoforms ubiquitinate individual epithelial sodium channel subunits and reduce ... "Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles from Mdm2 in receptor ...
  https://en.wikipedia.org/wiki/Ubiquitin_C
*  Calcineurin - Wikipedia
... cell receptor-induced calcineurin activation regulates T helper type 2 cell development by modifying the interleukin 4 receptor ... calcineurin A and a 19-kD Ca2+-binding regulatory subunit, calcineurin B. There are three isozymes of the catalytic subunit, ... Wang MG, Yi H, Guerini D, Klee CB, McBride OW (1996). "Calcineurin A alpha (PPP3CA), calcineurin A beta (PPP3CB) and ... Liu L, Zhang J, Yuan J, Dang Y, Yang C, Chen X, Xu J, Yu L (March 2005). "Characterization of a human regulatory subunit of ...
  https://en.wikipedia.org/wiki/Calcineurin
*  Method for treating a metastatic carcinoma using a conditionally lethal gene - Patent # 5997859 - PatentGenius
... alpha. or .beta. globinpromoter, T-cell receptor promoter, the osteocalcin promoter the IL-2 promoter, IL-2 receptor promoter, ... subunit of the human and mouse CD3/T-cell antigen receptor complexes," Immunogenetics 26: 258-266, 1987... Ledley, "Somatic ... An Intracellular Protein From Helper/Inducer T Cells That Regulates Gene Expression of Interleukin 2 Receptor and human ... acetyl-choline receptor promoter, alcohol dehydrogenase promoter, .alpha. or .beta. globin promoters, T-cell receptor promoter ...
  http://www.patentgenius.com/patent/5997859.html
*  Ion channels in inflammation | SpringerLink
Interleukin-1 beta decreases expression of the epithelial sodium channel alpha-subunit in alveolar epithelial cells via a p38 ... The cytokine TNF-alpha increases the proportion of DRG neurons expressing the TRPV1 receptor via the TNFR1 receptor and ERK ... Bode H, Schmitz H, Fromm M, Scholz P, Riecken E-O, Schulzke J-D (1998) IL-1 beta and TNF alpha but not IFN-alpha, interferon- ... Zund G, Madara JL, Dzus AL, Awtrey CS, Colgan SP (1996) Interleukin-4 and interleukin-13 differentially regulate epithelial ...
  https://link.springer.com/article/10.1007%2Fs00424-010-0917-y
*  US Patent # 6,326,472. Human receptor proteins; related reagents and methods - Patents.com
... human receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also ... Typically, it will bind to its corresponding biological ligand, perhaps in a dimerized state with an alpha receptor subunit, ... "Cloning of a Novel Receptor Subunit, AcPL, Required for Interleukin-18 Signaling". .. D. Buck, GenBank, Accession No. Z68328, ... The IL-1.alpha. and IL-1.beta. ligands bind an IL-1 receptor type I (IL-1RD1) as the primary receptor and this complex then ...
  http://patents.com/us-6326472.html
*  ADCY8 - Wikipedia
"HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and ... Patke CL, Shearer WT (May 2000). "gp120- and TNF-alpha-induced modulation of human B cell function: proliferation, cyclic AMP ... that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase. GRCh38: Ensembl ... Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) ...
  https://en.wikipedia.org/wiki/ADCY8
*  PRKACB - Wikipedia
Four different regulatory subunits and three catalytic subunits of PKA have been identified in humans. The protein encoded by ... PRKACB has been shown to interact with Ryanodine receptor 2 and Low affinity nerve growth factor receptor. GRCh38: Ensembl ... Chen P, Mayne M, Power C, Nath A (1997). "The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications ... 1998). "Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via ...
  https://en.wikipedia.org/wiki/PRKACB